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| 1 | Prevalence and Early Signs of Autism Spectrum Disorder(ASD) among 18-36 Month Old Children in Tianjin of China显示文摘Objective The aim of this study is to estimate the prevalence of autism spectrum disorder(ASD) among 18-36 month old children in the Tianjin Municipality of China, and to identify early signs of autistic children and the predictability of each individual symptom. Methods A total of 8 000 children were screened to do a questionnaire based on CHAT modified to include more early signs of autism at the age of 18-36 months. Then the at-risk children were reexamined 1.5 years later and ASD children were identified based on DSM-IV. Early signs of autism were analyzed retrospectively by using discriminant function analysis performed among ASD children, children not followed up and children followed up but failing to meet ASD criteria. Results Three hundred and sixty seven children were screened as being at-risk to ASD, and 22 of them were identified as having ASD in the subsequent diagnosis. The prevalence of ASD was 27.5 per 10 000 in Tianjin of China with a male to female ratio of 4:1. Items addressing social interactions and communications had higher predictability than other items to distinguish autistic children from non-autistic ones. Pretend play, functional play, showing and reading parents' facial expressions distinguished autistic children from those not followed up, nevertheless those followed up but failing to meet ASD criteria were not included. Conclusion The prevalence of ASD found in our study was lower than that reported in some studies by western researchers. Autism has its specific symptoms, such as deficits in social awareness, social relatedness, and social referencing. | HUANG Jun Ping CUI Shan Shan HAN Yu IRVA Hertz-Picciotto QI Li Hong ZHANG Xin | 2014 | Biomedical and Environmental Sciences2014，27，6： | 7 |
| 2 | Prenatal and Perinatal Risk Factors for Autism in China显示文摘 | Xin Zhang Cong-Chao Lv Jiang Tian Ru-Juan Miao Wei Xi Irva Hertz-Picciotto Lihong Qi | 2010 | Journal of Autism and Developmental Disorders2010，，11： | 1 |
| 3 | Blood lead levels measured prospectively and risk of spontaneous abortion显示文摘 | Borja Aburto VH Irva HP Lopez MR | 1999 | Am J Epidemiol1999，150，： | 1 |
| 4 | Prenatal Vitamins, One-carbon Metabolism Gene Variants, and Risk for Autism显示文摘 | Rebecca J. Schmidt Robin L. Hansen Jaana Hartiala Hooman Allayee Linda C. Schmidt Daniel J. Tancredi Flora Tassone Irva Hertz-Picciotto | 2011 | Epidemiology2011，，4： | 1 |
| 5 | Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome显示文摘 | Paul Ashwood Paula Krakowiak Irva Hertz-Picciotto Robin Hansen Isaac Pessah Judy Van de Water | 2010 | Brain Behavior and Immunity2010，，1： | 1 |
| 6 | Maternal Immune-Mediated Conditions, Autism Spectrum Disorders, and Developmental Delay显示文摘 | Kristen Lyall Paul Ashwood Judy Water Irva Hertz-Picciotto | 2014 | Journal of Autism and Developmental Disorders2014，，7： | 1 |
| 7 | Increased Anti-Phospholipid Antibodies in Autism Spectrum Disorders显示文摘 | Milo Careaga Robin L. Hansen Irva Hertz-Piccotto Judy Van de Water Paul Ashwood Giuseppe Valacchi | 2013 | Mediators of Inflammation2013，，： | 1 |
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