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| 1 | Does Helicobacter pylori infection eradication modify peptic ulcer prevalence? A 10 years' endoscopical survey显示文摘瞄准:为了在病人比较消化性溃疡流行,在根除治疗的进步散开以后在 pre-Helicobacter 时代和十年在二所意大利的医院里为上面的胃肠的内视镜检查法参考了。方法:我们检查了连续地在 1992 和 2002 期间在 1986-1987 和 1995-1996 期间在 Padova 的肠胃病学单位,并且在 Parma 的肠胃病学单位执行的所有内视镜的考试。迟平方测试被用于统计分析。结果:从两个的数据内视镜的中心在溃疡的流行显示出统计上重要的减少:从 12.7% ~ 6.3%(P<0.001 ) 在 Padova 并且从 15.6% ~ 12%(P<0.001 ) 在 Parma。减少两个都是重要的为十二指肠(从 8.8% ~ 4.8% , P<0.001 ) 并且胃溃疡(3.9% ~ 1.5% , P<0.001 ) 在 Padova,并且仅仅为在 Parma 的十二指肠溃疡(9.2% ~ 6.1% , P<0.001;胃溃疡:6.3% ~ 5.8% , NS ) 。结论:在征兆的病人的根除在消化性溃疡流行导致了重要减小的广泛的 Helicobacter pylori (H pylori ) 的十年。这减小在 Padova 是特别地明显的,在为在一般 practioners 之中的 H pylori 根除的致敏的一个工程在 1990 和 1992 之间被执行的地方。假如我们的假设应该是真的, H pylori 根除可能在未来导致是的消化性溃疡一稀罕内视镜的发现。 | Giorgio Nervi Stefania Liatopoulou Lucas Giovanni Cavallaro Alessandro Gnocchi Nadia Dal Bò Massimo Rugge Veronica Iori Giulia Martina Cavestro Marta Maino Giancarlo Colla Angelo Franzè Francesco Di Mario | 2006 | World Journal of Gastroenterology2006，12，15： | 5 |
| 2 | Efficacy of a therapeutic strategy for eradication of Helicobacter pylori infection显示文摘AIM: To determine the efficacy of our therapeutic strategy for Helicobacter pylori (H. pylori) eradication and to identify predictive factors for successful eradication. METHODS: From April 2006 to June 2010, we retrospectively assessed 2428 consecutive patients (1025 men, 1403 women; mean age 55 years, age range 18-92 years) with gastric histology positive for H. pylori infection referred to our unit for 13-C urea breath test(UBT), after first-line therapy with proton pump inhibitor (PPI) b.i.d. + amoxicillin 1 g b.i.d. + clarithromycin 500 mg b.i.d. for 7 d. Patients who were still positive to UBT were recommended a second-line therapy (PPI b.i.d. + amoxicillin 1 g b.i.d. + tinidazole 500 mg b.i.d. for 14 d). Third choice treatment was empirical with PPI b.i.d. + amoxicillin 1 g b.i.d. + levofloxacin 250 mg b.i.d. for 14 d. RESULTS: Out of 614 patients, still H. pylori-positive after first-line therapy, only 326 and 19 patients respectively rechecked their H. pylori status by UBT after the suggested second and third-line regimens. 'Per protocol' eradication rates for first, second and thirdline therapy were 74.7% (95% CI: 72.7%-76.4%), 85.3% (95% CI: 81.1%-89.1%) and 89.5% (95% CI: 74.9%-103%) respectively. The overall percentage of patients with H. pylori eradicated after two treatments was 97.8% (95% CI: 97.1%-98.4%), vs 99.9% (95% CI: 99.8%-100%) after three treatments. The study found that eradication therapy was most effective in patients with ulcer disease (P < 0.05, P = 0.028), especially in those with duodenal ulcer. Smoking habits did not significantly affect the eradication rate. CONCLUSION: First-line therapy with amoxicillin and clarithromycin produces an H. pylori eradication rate comparable or superior to other studies and secondline treatment can still be triple therapy with amoxicillin and tinidazole. | Giuliana Sereni Francesco Azzolini Lorenzo Camellini Debora Formisano Francesco Decembrino Veronica Iori Cristiana Tioli Maurizio Cavina Francesco Di Mario Giuliano Bedogni Romano Sassatelli | 2012 | World Journal of Gastroenterology2012，18，33： | 4 |
| 3 | miR147b:白细胞介素-1β介导的人类星形胶质细胞炎症中的新型关键调节因子显示文摘星形胶质细胞是大脑炎症过程的重要介质,可能在包括癫痫在内的几种神经系统疾病中起重要作用。星形胶质细胞中可生产几种miRNA,是炎症通路的关键调节因子,还可能用作治疗靶标。本研究将探索在体外IL-1β介导的炎症条件下,星形胶质细胞内生成的miRNA及其功能,并在人癫痫脑组织中验证。我们通过测序评估IL-1β刺激的人胎儿星形胶质细胞培养物中的miRNA和mRNA表达。使用miRNA模拟物在细胞培养物中过表达miRNA。使用原位杂交技术检测患有结节性硬化症复合体或颞叶癫痫伴海马硬化患者的切除脑组织中miRNA的表达。我们发现了2种差异表达的miRNA:miR146a和miR147b,它们与免疫/炎症反应相关基因的表达增加有关。既往有研究报道,在星形胶质细胞和结节性硬化复合细胞培养物中使用IL-1β刺激后,miR147b的过表达降低了促炎介质IL-6和COX-2的表达。miR146a和miR147b过表达降低了星形胶质细胞的增殖并促进人神经干细胞的神经元分化。miR147b在致癫痫脑中的星形胶质细胞中表达增加。由于其抗炎和恢复异常星形细胞增殖和促进神经元分化的能力,miR146a和miR147b作为与炎症相关的神经疾病(例如癫痫)的潜在治疗靶标值得进一步研究。 | van Scheppingen J Mills JD Zimmer TS Broekaart DWM Iori V Bongaarts A Anink JJ Iyer AM Korotkov A Jansen FE van Hecke W Spliet WG van Rijen PC Baayen JC Vezzani A van Vliet EA Aronica E 聂昊 | 2018 | 神经损伤与功能重建2018，13，12： | 3 |
| 4 | Bipolar transurethral resection of prostate: clinical and urodynamic evaluation显示文摘 | Iori F Franco G Leonardo C Laurenti C Tubaro A D-Amico F | 2008 | Urology2008，71，： | 1 |
| 5 | Bipolar transurethral resection of prostate: clinical and urodynamic evaluation 显示文摘 | IORI F FRANCO G LEONARDO C | 2008 | Urology2008，71，2： | 1 |
| 6 | A hybrid genetic algorithm for the two-dimensional single large object placement problem显示文摘 | ELENI Hadjiconstantinou MANUEL Iori | 2007 | European Journal of Op erational Research2007，183，3： | 1 |
| 7 | In situ protein Kinase C activity is increased in cultured fibroblasts from Type 1 diabetic patients with nephropathy显示文摘 | E. Iori M. C. Marescotti M. Vedovato G. Ceolotto A. Avogaro A. Tiengo S. Del Prato R. Trevisan Dr | 2003 | Diabetologia2003，，4： | 1 |
| 8 | Clinical and pressure-flow chan-ges after long-term treatment with alfuzosin SR显示文摘 | DeNunzio C Franco G Iori F | 2003 | Urol Int2003，71，1： | 1 |
| 9 | Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures显示文摘 | Iori V Maroso M Rizzi M | 2013 | Neurobiol Dis2013，58，： | 1 |
| 10 | IMAT-SIM : a new method for the clinical dosimetry of intensity-modulated arc therapy (IMAT)显示文摘 | Iori M Cagni E Nahum AE | 2007 | Med Phys2007，34，7： | 1 |
| 11 | Introduction to Needs Analysis 显示文摘 | Son^iori MH | 2008 | ESPWorld2008，，4： | 1 |
| 12 | Bipolar transurethral resection of prostate : clinical and urodynamic evaluation 显示文摘 | IORI F FRANCO G LEONARDO C | 2008 | J Urol2008，71，2： | 1 |
| 13 | Acute effects of non-invasive ventilatory support on functional mitral regurgitation in patients with exacerbation of congestive heart failure显示文摘 | Andrea Bellone Andrea Barbieri Caterina Ricci Emilio Iori Mario Donateo Monica Massobrio Stefano Bendinelli | 2002 | Intensive Care Medicine2002，，9： | 1 |
| 14 | Proven Epstein-Barrencephalitis with negative EBV-DNA load in cerebrospi-nal fluid after allogeneic hematopoietic stem cell trans-plantation in a child with acute lymphoblastic leukemia显示文摘 | Barberi W Perrone S Iori AP | 2015 | Pediatr Transplant2015，19，1： | 1 |
| 15 | Idarubicin intensified BUCY2 regimen in allogeneic unmanipulated transplant for high-risk hematological malignancies 显示文摘 | Mengarelli A Iori AP Guglielmi C | 2000 | Leukemia2000，14，12： | 1 |
| 16 | 64-detector row CT cystography with virtual cystoscopy in the detection of bladder carcinoma: preliminary experience in selected patients显示文摘 | V. Panebianco M. Osimani D. Lisi E. Santucci M. Ciccariello S. Iori C. Catalano R. Passariello | 2009 | La radiologia medica2009，，1： | 1 |
| 17 | High-mobility group box- 1 impairs memory in mice through both toll-like receptor 4 and Receptor for Advanced Glycation End Products显示文摘 | Mazarati A Maroso M Iori V | 2011 | Exp Neurol2011，232，2： | 1 |
| 18 | (RS)-glucoraphanin purified from Tuscan black kale and bioactivated with myrosinase enzyme protects against cerebral ischemia/reperfusion injury in rats显示文摘 | Giacoppo S Galuppo M Iori R | 2014 | Fitoterapia2014，99，12： | 1 |
| 19 | Young women, cervical intraepithelial neoplasia and human papillomavirus: risk factors for persistence and recurrence 显示文摘 | Frega A Stentella P De Ioris A | 2003 | Cancer Lett2003，196，： | 1 |
| 20 | A micro-simulation traders' activity in the stock market: the rule of heterogeneity, agents' interactions and trade friction显示文摘 | Iori G | 2002 | Journal of Economic Behaviour and Organization2002，49，： | 1 |
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