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	题名	作者	年代	出处	被引量
1	The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells显示文摘Streptococcus mitis(S. mitis) is a pioneer commensal bacterial species colonizing many of the surfaces of the oral cavity in healthy individuals. Yet, not much information is available regarding its interaction with the host. We used examination of its transcriptional regulation in oral keratinocytes to elucidate some of its potential roles in the oral cavity. Transcription factor analysis of oral keratinocytes predicted S. mitis-mediated activation of aryl hydrocarbon receptor(Ah R). Activation and functionality of Ah R was confirmed through nuclear translocation determined by immunofluorescence microscopy and real-time polymerase chain reaction with reverse transcription analysis of CYP1A1, the hallmark gene for Ah R activation. Addition of Streptococcus mutans or Streptococcus gordonii did not induce CYP1A1 transcription in the keratinocyte cultures. Introduction of an Ah R-specific inhibitor revealed that S. mitis-mediated transcription of CXCL2 and CXCL8 was regulated by Ah R. Elevated levels of prostaglandin E2(enzyme-linked immunosorbent assay) in supernatants from S. mitis-treated oral epithelial cells were also attenuated by inhibition of Ah R activity. The observed Ah R-regulated activities point to a contribution of S. mitis in the regulation of inflammatory responses and thereby to wound healing in the oral cavity. The concept that the oral commensal microbiota can induce Ah R activation is important, also in view of the role that Ah R has in modulation of T-cell differentiation and as an anti-inflammatory factor in macrophages.	stian a engen gro h rørvik olav schreurs inger js blix karl schenck	2017	International Journal of Oral Science2017，9，3：	2
2	Can the Proximal Femoral Nail be Improved?显示文摘	Inger B. 1 8 Phone Fax e-mail: Schipper MD PhD Roger K. J. Simmermacher Tobias Hüttl R?bi Frigg Peter Messmer Michael Schütz Andreas Lenich Chris Werken	2005	European Journal of Trauma2005，，3：	1
3	Identification and characterization of pathogenic Aerornonas veronii biovar, sobria associated with epizootic ulcerative syndrome in fish in Bangladesh显示文摘	MOKHLASUR R PATRICIA C INGER K	2002	Appl Environ Microbiol2002，68，2：	1
4	Increased plasma endothelin - 1 in acute ischemic stroke显示文摘	Ziv Flem inger G D jalaetti R et a\|	1992	Stroke1992，23，7：	1
5	Source partitioning using stable isotopes: coping with too muchvariation 显示文摘	Parnell A C Inger R Bearhop S	2010	PLoS ONE2010，5，3：	1
6	The Uniform Commercial Code in the of Comparative Law 显示文摘	SCHLES INGER R B	1959	Inter - American Law Review1959，18，1：	1
7	Source partitioning using stable isotopes: coping with too much variation显示文摘	Parnell A C Inger R Bearhop S	2010	PLoS One2010，5，3：	1
8	Leaf composition in relation to smoking quality and aroma显示文摘	Enzell C R Inger W	1980	Rec Adv Tob Sci1980，，6：	1
9	Tobacco isoprenoids-precursors of important aroma constituents显示文摘	Curt R Enzell Inger Wahlberg	1990	Pure&Appl Chem1990，62，7：	1
10	Source Partitioning Using Stable Isotopes: Coping with Too Much Variation显示文摘	Parnell A C Inger R Bearhop S Jackson AL	2010	PLoS ONE2010，5，3：	1
11	Leaf composition in relation to smoking quality and aroma显示文摘	Enzell C R Inger W	1997	Rec AdvTob Sci1997，，3：	1
12	Evolution of pancreas transplantation:long-term results and perspectives from a high-volume center显示文摘	Ol inger R Margreiter C B?smül er C		0，，05：	1
13	Nonequilibrium viscous shock-layer heat transfer with arbitrary surface catalycit显示文摘	Inger G R	2005	Journal of Spacecraft and Rockets2005，42，2：	1
14	Leaf composition in relation to smoking quality and aroma显示文摘	ENZELL C R INGER W	1980	Rec Adv Tob Sci1980，，6：	1
15	Effect of feeding different levels of foliage of Moringa oleifera to creole dairy cows on intake,digestibility, milk production and composition显示文摘	NADIR R S EVA S INGER L	2006	Livestock Science2006，10，1：	1
16	Properties of CsI(Tl)crystals and their optimization for calorimetry of high energy photon显示文摘	BROSE J DA HL INGER G SCHUBERT K R	1998	Nucl Instrum Methods A1998，417，：	1
17	Creating a manufacturing environment that is in harmony with the market-the 'how' of supply chain management显示文摘	Inger R Braithwaite A Christopher M	1995	Production Planning and Control1995，6，3：	1
18	Surviving sepsis Campaign guidelines for management of severe sepsis and septic shock显示文摘	Phil ip-Del inger R Jean-Carlet M Henry M		0，，03：	1
19	Differential immediate early gene expression in conditional hepatitis B virus pXtransforming versus nontransfonning hepatocyte cell hrms显示文摘	TARN C BILODEAU M L HUI J INGER R L	1999	J Biol Chem1999，274，4：	1
20	Source parti- tioning using stable isotopes:Coping with too much variation 显示文摘	PARNELL A C INGER R BEARHOP S	2010	PLOS ONE2010，5，3：	1

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