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| 1 | Ultra-thin, planar, Babinet-inverted plasmonic metalenses显示文摘We experimentally demonstrate the focusing of visible light with ultra-thin,planar metasurfaces made of concentrically perforated,30-nm-thick gold films.The perforated nano-voids—Babinet-inverted(complementary)nano-antennas—create discrete phase shifts and form a desired wavefront of cross-polarized,scattered light.The signal-to-noise ratio in our complementary nano-antenna design is at least one order of magnitude higher than in previous metallic nano-antenna designs.We first study our proof-of-concept‘metalens’with extremely strong focusing ability:focusing at a distance of only 2.5 mm is achieved experimentally with a 4-mm-diameter lens for light at a wavelength of 676 nm.We then extend our work with one of these‘metalenses’and achieve a wavelength-controllable focal length.Optical characterization of the lens confirms that switching the incident wavelength from 676 to 476 nm changes the focal length from 7 to 10 mm,which opens up new opportunities for tuning and spatially separating light at different wavelengths within small,micrometer-scale areas.All the proposed designs can be embedded on-chip or at the end of an optical fiber.The designs also all work for two orthogonal,linear polarizations of incident light. | Xingjie Ni Satoshi Ishii Alexander V Kildishev Vladimir M Shalaev | 2013 | Light(Science & Applications)2013，2，1： | 20 |
| 2 | 脑缺血后N-myc下游调控基因2保护血脑屏障完整性显示文摘脑缺血后血脑屏障(BBB)的破坏与外周细胞向脑内浸润、病孔损形成与进展、以及临床病程恶化密切相关。目前BBB完整性的调控机制,尤其是在永久性缺血后的调控机制尚未明确。本研究使用小鼠永久性脑缺血模型进行相关研究,结果显示,星形胶质细胞N-myc下游调控基因2(NDRG2)可能是缺血性脑卒中后BBB通透性的调控分子,该分子与分化和应激相关。免疫组化显示,在永久性大脑中动脉闭塞(MCAO)后,NDRG2在星形胶质细胞中的表达显著增加。敲除NDRG2基因,脑梗死体积增加,免疫细胞在缺血同侧大脑半球积聚增加。MCAO后,NDRG2基因敲除小鼠缺血侧皮质的缺血灶内及灶周血管周围区域内的血清蛋白(包括纤维蛋白原和免疫球蛋白)的外渗增强此之,MCAO后NDRG2基因敲除小鼠体内基质金属蛋白酶(MMPs)的表达也显著增加。在细胞培养中,NDRG2-/-星形胶质细胞中MMP-3的表达和分泌增加,这种增加可被腺病毒介导的NDRG2再表达所逆转。综上所述,脑缺血后,星形胶质细胞内的NDRG2可能通过调节MMP的表达,而在BBB通透性的调节和免疫细胞浸润中起到重要作用。 | Takarada-Iemata M Yoshikawa A Ta HM Okitani N Nishiuchi T Aida Y Kamide T Hattori T Ishii H Tamatani T Le TM Roboon J Kitao Y Matsuyama T Nakada M Hori O 聂昊 | 2018 | 神经损伤与功能重建2018，13，4： | 4 |
| 3 | Callus induction and somatic embryogenesis of Phalaenopsis显示文摘 | Ishii Y Takamura T Goi M | 1998 | Plant Cell Reports1998，17，67： | 2 |
| 4 | Cloning and sequencing of the gene encoding Toho-2, a class A β-lactamase preferentially inhibited by tazobactam 显示文摘 | Ma L Ishii Y Ishiguro M | 1998 | Antimicrob Agents Chemotherapy1998，42，5： | 2 |
| 5 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 6 | Gastric acid stimulating action of cysteamine in the rat 显示文摘 | Ishii Y Fujii Y Hoa M | 1976 | Eur J Pharmacol1976，36，： | 2 |
| 7 | Design for variety:developing standardized and modularized product platform architectures显示文摘 | MARTIN M V ISHII K | 2002 | Research in Engineering Design2002，13，4： | 1 |
| 8 | High serum levels of thrombospondin-1 in patients with idiopathic interstitial pneumonia 显示文摘 | Ide M Ishii H Mukae H | 2008 | Respir Med2008，102，11： | 1 |
| 9 | Rhamnogalacturonan II: structure and function of a borate cross-linked cell wall pectic pelysaccharide显示文摘 | O'Neill M A Ishii T Albersheim P | 2004 | Armu Rev Plant Biol2004，55，： | 1 |
| 10 | Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha synuelein: Implication for alpha-synueleinopathies显示文摘 | ISHII A NONAKA T TANIGUCHI S SAOTO T ARAI T MANN D IWATSUBO T HISANAQA S GOEDERT M HASEQAWA M | 2007 | FEBS Lett2007，581，24： | 1 |
| 11 | Short-term of high glucose concen-tration induces generation of reactive species in endothelial cells:impli-cation for the oxidative stress associated with postprandial hypcrglycemi-a显示文摘 | Hasegawa G Ishii M et ol | 2004 | Redox Rep2004，9，2： | 1 |
| 12 | Structure of neutral branched xylooligosaccharides produced by xylanase from in situ reduced hardwood xylan显示文摘 | NISHIMURA T ISHIHARA M ISHII T | 1998 | Carbohydrate Research1998，308，12： | 1 |
| 13 | Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase 显示文摘 | Watashi K Ishii N Hijikata M | 2005 | Mol Cell2005，19，1： | 1 |
| 14 | Quantitation of the global right ventricular function in children with normal heart and congenital heart disease: a right ventricular myocardial performance index显示文摘 | Ishii M Eto G Tei C | 2000 | Pediatr Cardiol2000，21，5： | 1 |
| 15 | 显示文摘 | Hayekawa M Karaguchi S Ishii S | 1997 | Int J Cancer1997，71，6： | 1 |
| 16 | Searless endoscopic thyroidectomy: breastapproach for better cosmesis显示文摘 | Ohgarni M Ishii S Arisawa Y | 2000 | Surg Laparosc Endosc Percutan Tech2000，10，1： | 1 |
| 17 | Immunotherapeutic utility of stimulatory and suppressive oligodeoxynucleotides显示文摘 | Ishii KJ Gursel I Gursel M | 2004 | Curr Opin Mol Ther2004，6，2： | 1 |
| 18 | Scarless endoscopic thyroidectomy:breast approach for better cosmesis显示文摘 | Ohgami M Ishii S Arisawa Y | 2000 | Surg Laparosc Endosc2000，10，1： | 1 |
| 19 | Sequential follow-up results of catheter intervention for coronary artery lesions after Kawasaki disease:quantitative comary artery angiography and intravascular ultrasound imaging study 显示文摘 | Ishii M Ueno T Ikeda H | 2002 | Circulation2002，105，25： | 1 |
| 20 | The fine structure in the field change produced by positive ground stroke 显示文摘 | Hojo J Ishii M Kawamura T | 1985 | J Geo- physRes1985，90，： | 1 |
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