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| 1 | Mycoplasma infections and different human carcinomas显示文摘AIM To explore relationships between human carcinomas and mycoplasma infection.METHODS Monoclonal antibody PD4, which specifically recognizes a distinct protein from mycoplasma hyorhinis, was used to detect mycoplasma infection in different paraffinembedded carcinoma tissues with immunohistochemistry. PCR was applied to amplify the mycoplasma DNA from the positive samples for confirming immunohistochemistry.RESULTS Fifty of 90 cases (56%) of gastric carcinoma were positive for mycoplasma hyorhinis. In other gastric diseases, the mycoplasma infection ratio was 28% (18/49) in chronic superficial gastritis, 30% (14/ 46) in gastric ulcer and 37% (18/ 49) in intestinal metaplasia. The difference is significant with gastric cancer (X2=12.06, P<0.05). In colon carcinoma, the mycoplasma infection ratio was 55.1% (32/58), but it was 20.9% (10/49) in adenomarous polyp (X2=13.46, P<0.005).Gastric and colon cancers with high differentiation had a higher mycoplasma infection ratio than those with low differentiation (P< 0.05). Mycoplasma infection in esophageal cancer, lung cancer, breast cancer and glioma was 50.9% (27/53), 52.6% (31/ 59), 39.7%(25/63) and 41% (38/91), respectively. The mycoplasma DNA was successfully amplified with the DNA extracted from the cancer tissues that were positive for mycoplasma infection (detected with antibody PD4).CONCLUSION There was high correlation between mycoplasma infection and different cancers, which suggests the possibility of an association between the two. The mechanism involved in oncogenesis by mycoplasma remains unknown. | Su Huang Ji You Li Jan Wu Lin Meng Cheng Chao Shou Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100034. ChinaSu Huang, received B. A from Jiangxi Medical College of China in 1994. Now she is a graduate student pursuing a Ph. D degree at the Peking University School of Oncology. | 2001 | World Journal of Gastroenterology2001，7，2： | 18 |
| 2 | 一种解列车控制问题的新算法显示文摘本文提出一种解列车控制问题的新算法。该算法基于遗传算法、罚函数法和RungaKuta法。 | CHENG JinSong (Dept. of Computer, Anhui University, Hefei AH,230039) In this paper, we present a new algorithm for solving train control problem. The algorithm is based on genetic algorithm, penalty function method and the RungaKutta method. | 1999 | 微机发展1999，9，4： | 4 |
| 3 | Modulation of C -reactive protein mediated monocyte chemoattraetaut protein-1 induction inhuman endothelial cells by antiathemsele rosis drugs显示文摘 | Paseeri V Cheng IS Willerson IT | 2001 | Circula- tion2001，103，21： | 1 |
| 4 | Secondary metabolites isolated from the fungus Monascus Pilosus显示文摘 | Cheng MJ Wu MD Chen IS | | 0，，5： | 1 |
| 5 | Regulation of cell prolifera- tion by the opioid growth factor receptor is dependent on karyo- pherin beta and Ran for nucleocytoplasmic afficking 显示文摘 | Cheng F McLaughlin PJ Zagon IS | 2010 | Exp Biol Med (Maywood)2010，235，9： | 1 |
| 6 | Clinical application prospects of gastric pacing for treating postoperative gastric motility disorders 显示文摘 | Li FY Jiang IS Cheng JQ | 2007 | J Gastroenterol Hepatol2007，22，12： | 1 |
| 7 | Study on Eposy compound fixation显示文摘 | Sung HW Cheng WH Chiu IS | 1996 | Biomed Mater Rearch1996，33，： | 1 |
| 8 | Coincident linkage of fasting plasma insulin and blood pressure to chromosome 7q in hypertensive Hispanic families 显示文摘 | Cheng IS Davis RC Raffel LJ | 2001 | Circulation2001，104，11： | 1 |
| 9 | Involvement of the PI3K/ Akt signaling pathway in platelet-derived growth factor-inducedmigration of human lens epithelial cells 显示文摘 | Xiong W Cheng BH Jia SB Tang IS | 2010 | Curr Eye Res2010，35，5： | 1 |
| 10 | Potential side effects of renin inhibitors-meehanisms based on comparison with other renin-angiotension bockers显示文摘 | CHENG HF HARR IS RC | 2006 | Expert Opin D rug Saf2006，5，5： | 1 |
| 11 | Supplementation of eleutherococcus senticosus (CIWUJIA) on anti-fatigue function in human 显示文摘 | J Kuo HC Yang IS Cheng | 2005 | The 18th International Congress of Nutrition in South Africa2005，11，： | 1 |
| 12 | Purification,antioxidant activity and antiglycation of polysaccharides from Polygonum muhiflorum Thunb显示文摘 | Lv IS Cheng YH Zheng TS | 2014 | Carbohydr Polym2014，99，： | 1 |
| 13 | Acute renal failure associated with Yersinia pseudotuberculosis 显示文摘 | Cheng HI Choi EH Ha IS | 1995 | Nephron1995，70，： | 1 |
| 14 | Effect of postexercise carbohydrate supplementation on glucose uptake-associated gene expression in the human skeletal muscle显示文摘 | Cheng IS Lee NY Liu KL Liao SF Huang CH Kuo CH | 2005 | J Nutr Biochem2005，16，5： | 1 |
| 15 | Contribution and regulation ofTRPC channels in store-operated Ca2+ entry显示文摘 | Cheng KT Ong HL Ambudkar IS | 2013 | Curr Top Membr2013，71，： | 1 |
| 16 | Evaluation of the Bruker Bioty- per matrix-assisted laser desorption ionization-time of flight mass spec- trometry system for identification of blood isolates of Vibrio species 显示文摘 | Cheng WC Jan IS Chen JM | 2015 | J Clin Microbiol2015，53，5： | 1 |
| 17 | Studies on epoxy compound fixation显示文摘 | Sung HW Cheng WH Chiu IS | 1996 | J Biomed Mater Res1996，33，3： | 1 |
| 18 | G-CSF prevents progression of diabetic nephropathy in rat显示文摘 | Byung IS Yi SS Cheng HF | 2013 | PLOS ONE2013，8，77： | 1 |
| 19 | Evaluation of the Bruker Bioty- per matrix-assisted laser desorption ionization-time of flight mass spectrometry system for identification of blood isolates of Vibrio spe- cies显示文摘 | Cheng WC Jan IS Chen JM | 2015 | Clin Microbiol2015，53，5： | 1 |
| 20 | The opioid growth factor (OGF)-OGF receptor axis uses the p16 pathway to inhibit head and neck cancer显示文摘 | Cheng F Zagon IS Verderame MF | 2007 | Cancer Res2007，67，10： | 1 |
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