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43篇 您的检索式:作者名="IRINA R"
    题名 作者 年代 出处 被引量
1Immunopathogenesis of chronic hepatitis B显示文摘Chronic hepatitis B(CHB) is a widespread infectious disease with unfavorable outcomes and life-threatening consequences for patients, in spite of modern vaccination and antiviral treatment modalities. Cutting-edge experimental approaches have demonstrated key pathways that involve cross-talk between viral particles and host immune cells. All events, including penetration of hepatitis B virus(HBV) particles into host cells, establishing persistence, and chronization of CHB infection, and possibility of complete elimination of HBV particles are controlled by the immune system. Researchers have paid special attention to the replication capacity of HBV in host cells, which is associated with cellular changes that reflect presentation of viral antigens and variability of HBV antigen features. In addition, specific HBV proteins have an immune-modulating ability to initiate molecular mechanisms that 'avoid' control by the immune system. The relationship between immunological shifts and chronic infection stages has been intensively studied since it was recognized that the immune system is a direct participant in the recurrent(cyclic) nature of CHB. Understanding the wide diversity of molecular pathways and the crosstalk between innate and adaptive immune system components will provide fresh insight into CHB immune pathogenesis and the possibilities of developing new treatment strategies for this disease.Irina P Balmasova Nikolay D Yushchuk Ospan A Mynbaev Nageswara R Alla Elena S Malova Zhongjie Shi Chang-Lu Gao 2014World Journal of Gastroenterology2014,20,39:15
2Laparoscopic resection of exocrine carcinoma in central and distal pancreas results in a high rate of radical resections and long postoperative survival显示文摘Irina Pavlik Marangos Trond Buanes B?rd I. R?sok Airazat M. Kazaryan Arne R. Rosseland Krzysztof Grzyb Olaug Villanger ?ystein Mathisen Ivar P. Gladhaug Bj?rn Edwin 2012Surgery2012,,5:3
3Hydroxyethyl Starch Reduces Coagulation Competence and Increases Blood Loss During Major Surgery: Results From a Randomized Controlled Trial显示文摘Kirsten C. Rasmussen P?r I. Johansson Michael H?jskov Irina Kridina Thomas Kistorp Peter Thind Henning B. Nielsen Birgitte Ruhnau Tom Pedersen Niels H. Secher 2014Annals of Surgery2014,,2:2
4Long-Term Outcome of Laparoscopic Surgery for Pancreatic Neuroendocrine Tumors显示文摘Sven-Petter Haugvik Irina Pavlik Marangos B?rd Ingvald R?sok Ewa Pomianowska Ivar Prydz Gladhaug ?ystein Mathisen Bj?rn Edwin 2013World Journal of Surgery2013,,3:2
5Structure of antigenic sites on the haemagglutinin molecule of H5 avian influenza virus and phenotypic variation of escape mutants显示文摘Nikolai V K Irina A R Natalia A I 2002J Gen Virol2002,83,:1
6Epitope mapping of the hemagglutinin molecule of a highly pathogenic HSN1 influenza virus by using monoclonal antibodies显示文摘Nikolai V K Irina A R Elena A G 2007J Virol2007,81,12:1
7Biodegradation of organophosphorus pestiddea by surface-expressed organophosphorus hydrolase显示文摘Richard D R Irina K Wilfred C 1997Nature Bioteehnology1997,15,10:1
8Structure of anti- gen-ic sites on the haemagglutinin molecule of H5 avian influen- za v-irus and phenotypic variation of escape mutants 显示文摘Nikolai V K Irina A R Natalia A I 2002J Gen Virol2002,83,:1
9Sparse signal reconstruction from limited data using focus: a re-weighted minimum norm al- gorithm 显示文摘IRINA F G BHASKAR D R 1997IEEE Transactions on Signal Processing1997,45,3:1
10Oxidative-nitrosative stress and poly(ADP-ribose)polymerase(PARP)ac-tivation in experimental diabetic neuropathy:the relation is revisi-ted显示文摘Irina G Obrosova Viktor R Drel 2005Diabetes2005,54,12:1
11In stiu polymerized polyaniline films 显示文摘Anarea R Martin H Irina S 2002Journal of Colloid and Interface Science2002,248,:1
12CD4+ T cells inhibit growth of Epstein-Barr virus-transformed B cells through CD95-CD9s ligand-mediated apoptosis显示文摘Wilson AD Irina R Williams NA 1998Int Immunol1998,10,8:1
13Exploring anisotropy in removal rate for single crystal sapphire using MRF显示文摘Kozhinova Irina A Arrasmith Steven R Lambropoulos John C 2001The international society for optical engineering2001,4451,:1
14Structure-based design and synthesis of series of hydroxamic acids with a quaternary-hydroxy group in P1 as inhibitors of matrix 显示文摘Irina C J Prabhakar G R 1998Bioorganic & Medicinal Chemistry Letters1998,,6:1
15CD4 + T cells inhibit growth of Epstein-Barr virus-transformed B cells through CD95-CD95 ligand mediated apoptosis显示文摘WILSON AD IRINA R WILLIAMS NA 1998Int Immunol1998,10,8:1
16Synthetic strategy for Fe - MCM -41 catalyst: A key factor for homogeneous or heterogeneous phenol ox- idation 显示文摘SERGEY V S IRINA 1c M BORIS V R 2011Catal Sci Technol2011,1,6:1
17Exploring anisotropy in removal rate for single crystal sapphire using MRF显示文摘Kozhinova Irina A Arrasmith Steven R Lambropoulos John C 2001The International Society for Optical Engineering2001,4451,:1
18Robe~Ackrill EU rural development policy in the new member states 显示文摘Irina R^muiceanua 2007Promoting multifunctionality2007,23,4:1
19Synthesis and evaluation of caffeic acid amides as antioxidants 显示文摘Padinchare R Irina V Paul C 2001Bioorg Med Chem Lett2001,11,:1
20Chromatin acetylation status in the manifestation of neurodegenerative diseases: HDAC inhibitors as therapeutic tools 显示文摘Anne- Laurence B Caroline R Irina P 2007Subcell Biochem2007,41,:1
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