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| 1 | Serum leptin levels and insulin resistance are associated with gallstone disease in overweight subjects显示文摘AIM: To establish an association between the serum leptin levels and the development of gallstone disease (GD).METHODS: We carried out a non-matched case-controlled study in a university hospital in Mexico City. Two hundred and eighty-seven subjects were included: 97 cases with gallstones and 190 controls. Body mass index (BMI), fasting plasma leptin, insulin, serum lipid, and lipoprotein levels were measured. Insulin resistance was calculated by homeostasis model assessment (HOMA-IR). Unconditional logistic regression analysis (univariate and multivariate)stratified by BMI was used to calculate the risk of GD.RESULTS: The multivariate conditional regression analysis revealed a model for those patients with BMI <30. The selected variables in the model were HOMA-IR index with OR = 1.31, P= 0.02 and leptin higher than median with OR = 2.11, P= 0.05. In the stratum of BMI ≥30, we did not find a useful model.CONCLUSION: We concluded that insulin resistance and the development of GD appears to be associated with serum leptin levels in subjects with overweight, but not in obese subjects with similar metabolic profiles. | Nahum Méndez-Sánchez Luisa B Bermejo-Martínez Yolanda Vi(n|~)als Norberto C Chavez-Tapia Irina Vander Graff Guadalupe Ponciano-Rodríguez Martha H Ramos Misael Uribe | 2005 | World Journal of Gastroenterology2005，11，39： | 11 |
| 2 | Panax ginseng natural populations: their past, current state and perspectives显示文摘瞄准:人参属人参,遗传和它 Primorye (俄国) 的自然人口的个体发生的结构的交配系统被调查。方法:基因差异用紧密相联的酶和荧光灯地基于的自动化放大碎片长度多型性(AFLP ) 和简单顺序被估计重复(SSR ) 标记。结果:在种类水平的全部的基因差异与紧密相联的酶是低的试金(0.023 ) ,和有 AFLP (0.255 ) 和 SSR (0.259 ) 的高度方法。它根据紧密相联的酶(>99%) 在人口以内被观察, AFLP (>85%) ,和 SSR (>73%) 试金。基因可变性分发的索引指出开拓殖民地在早 Holocene 在温暖的时期期间从南部的避难处由人参的 Sikhote-Alin 种。到异花受粉和自花传粉的人参植物的能力被显示出,人参属人参是容许的单性生殖的植物的假设被证实。人参的繁殖系统拥有授精进程的高粘性和稳定性帮助种类处于压力条件幸存。外部或内部的因素引起的骚乱能由于人参小卵或单性生殖的胚胎开发的形态基因的潜力被减少。因为一些生活阶段是不在的或很少发生,人参人口的生活阶段结构的分析证明所有他们不是完整成分的。结论:在所有 3 张人口,处女和年轻生产个人是占优势的。人口学习了的这个工具是可行的,自然人参人口的再介绍还是可能的。 | Yuri N ZHURAVLEV Olga G KOREN Galina D REUNOVA Tamara I MUZAROK Tatiyana Yu GORPENCHENKO Irina L KATS Yuliya A KHROLENKO | 2008 | Acta Pharmacologica Sinica2008，29，9： | 3 |
| 3 | 16S rRNA targeted sandwich hybridization method for direct quantification of mycobacteria in soils 显示文摘 | Timo N Jaakko P Irina T | 2004 | Journal of Microbiological Methods2004，67，： | 1 |
| 4 | presynaptic remodeling contributes to activity dependent synaptogenesis显示文摘 | Irina N Pascal J Dominique M | 2003 | Neuroscience2003，23，24： | 1 |
| 5 | Presynaptic remodeling contributes to activity-dependen, synaptogenesis显示文摘 | Irina N Pascal J Dominique M | 2003 | Neuroscience2003，23，24： | 1 |
| 6 | Anthocyanins from black soybean seed coats stimulate wound healing in fibroblasts and keratinocytes and prevent inflammation in endothelial cells显示文摘 | IRINA T N YOUNG M K CHUNG J | 2009 | Food and Chemical Toxicology2009，47，11： | 1 |
| 7 | 显示文摘 | Savina Irina N Mattiasson Bo Galaeva Igor Yu | 2005 | Polymer2005，46，23： | 1 |
| 8 | Investigation of contact phenomena at cubic boron nitride-filler metal interface during electron beam brazing显示文摘 | Igor L P Alexey A S Irina G N | 1997 | Diamond and Related Materials1997，6，8： | 1 |
| 9 | Deoxygenation of dodecanoic acid under inert atmosphere显示文摘 | Heidi Bernas Kari Er?nen Irina Simakova Anne-Riikka Leino Krisztián Kordás Jukka Myllyoja P?ivi M?ki-Arvela Tapio Salmi Dmitry Yu. Murzin | 2009 | Fuel2009，，8： | 1 |
| 10 | The microRNA miR-181 targets the homeobox protein Hox-All during mammalian myoblast differentiation 显示文摘 | IRINA N MAYA A ANNA P | 2006 | Nature Cell Biol- ogy2006，8，3： | 1 |
| 11 | Comparative analysis of support mechanisms for renewable energy technologies using probability distributions 显示文摘 | Irina F Ken N | 2010 | Renewable Energy2010，35，6： | 1 |
| 12 | Studies on the biocompatibility of bacterial cellulose 显示文摘 | Fabia K Andrade N A Irina A | 2013 | Journal of Bioactive and Compatible Polymers2013，28，1： | 1 |
| 13 | Electrochemical and thermal properties of graphite electrodes with imidazolium- and piperi- dinium-based ionic liquids显示文摘 | Irina P A Choi N Roh S | 2009 | Power Sources2009，192，： | 1 |
| 14 | The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus显示文摘 | BERNADEYr B STEFANO A IRINA N | 2004 | The Journal of Neuroscience2004，24，10： | 1 |
| 15 | Mutants and intersexual heterokaryons of blakesleatrispora for production ofβ-carotene and lycopene显示文摘 | Bina J Mehta Irina N Obraztsova Enrique Cerdá-Olme-do | 2003 | Appl Environ Microbiol2003，69，7： | 1 |
| 16 | Ecological Momentary Assessment with smartphones for measuring mental health problems in adolescents显示文摘AIM To analyze the viability of Ecological Momentary Assessment(EMA) for measuring the mental states associated with psychopathological problems in adolescents.METHODS In a sample of 110 adolescents,a sociodemographic data survey and an EMA Smartphone application over a oneweek period(five times each day),was developed to explore symptom profiles,everyday problems,coping strategies,and the contexts in which the events take place.RESULTS The positive response was 68.6%.Over 2250 prompts about mental states were recorded.In 53% of situations the smartphone was answered at home,25.5% of casesthey were with their parents or with peers(20.3%).Associations were found with attention,affective and anxiety problems(P < 0.001) in the participants who took longer to respond to the EMA app.Anxious and depressive states were highly interrelated(rho = 0.51,P < 0.001),as well as oppositional defiant problems and conduct problems(rho = 0.56,P < 0.001).Only in 6.2% of the situations the subjects perceived they had problems,mainly associated with inter-relational aspects with family,peers,boyfriends or girlfriends(31.2%).We also found moderate-high reliability on scales of satisfaction level on the context,on positive emotionality,and on the discomfort index associated with mental health problems.CONCLUSION EMA methodology using smartphones is a useful tool for understanding adolescents' daily dynamics.It achieved moderate-high reliability and accurately identified psychopathological manifestations experienced by community adolescents in their natural context. | Ernesto Magallón-Neri Teresa Kirchner-Nebot Maria Forns-Santacana Caterina Calderón Irina Planellas | 2016 | World Journal of Psychiatry2016，6，3： | 1 |
| 17 | Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy显示文摘 | Sabine H Irina O Dan N | 2004 | J Allergy Clin Immunol2004，113，3： | 1 |
| 18 | Effects of glucagon-like peptide 1 analogs in combination with insulin on myocardial infarct size in rats with type 2 diabetes mellitus显示文摘AIM To evaluate the effects of glucagon-like peptide-1 analogs(GLP-1 a) combined with insulin on myocardial ischemiareperfusion injury in diabetic rats.METHODS Type 2 diabetes mellitus(T2 DM) was induced in maleWistar rats with streptozotocin(65 mg/kg) and verified using an oral glucose tolerance test. After anesthesia, the left coronary artery was occluded for 40 min followed by 80 min reperfusion. Blood glucose level was measured during surgery. Rats were randomized into six groups as follows:(1) control rats;(2) insulin(0.1 U/kg) treated rats prior to ischemia;(3) insulin(0.1 U/kg) treated rats at reperfusion;(4) GLP-1 a(140 mg/kg) treated rats prior to ischemia;(5) GLP-1 a(140 mg/kg) treated rats at reperfusion; and(6) rats treated with GLP-1 a(140 mg/kg) prior to ischemia plus insulin(0.1 U/kg) at reperfusion. Myocardial area at risk and infarct size was measured planimetrically using Evans blue and triphenyltetrazolium chloride staining, respectively.RESULTS There was no significant difference in the myocardial area at risk among groups. Insulin treatment before ischemia resulted in a significant increase in infarct size(34.7% ± 3.4% vs 18.6% ± 3.1% in the control rats, P < 0.05). Post-ischemic administration of insulin or GLP-1 a had no effect on infarct size. However, pre-ischemic administration of GLP-1 a reduced infarct size to 12% ± 2.2%(P < 0.05). The maximal infarct size reduction was observed in the group treated with GLP-1 a prior to ischemia and insulin at reperfusion(8% ± 1.6%, P < 0.05 vs the control and GLP-1 a alone treated groups).CONCLUSION GLP-1 a pre-administration results in myocardial infarct size reduction in rats with T2 DM. These effects are maximal in rats treated with GLP-1 a pre-ischemia plus insulin at reperfusion. | Vladislav A Zykov Taisiia P Tuchina Denis A Lebedev Irina B Krylova Alina Y Babenko Elvira V Kuleshova Elena N Grineva Alekber A Bayramov Michael M Galagudza | 2018 | World Journal of Diabetes2018，9，9： | 1 |
| 19 | Near-infrared laser photothermal therapy of cancer by using gold nanoparticles: computer simulations and experiment 显示文摘 | Irina L M Garif G A Boris N K | 2007 | Med Laser Appl2007，22，： | 1 |
| 20 | Fluores cence polarisation immunoassay based on a monoclonal antibody for the detection of sulphan-lethazine in chicken muscle显示文摘 | ZHANG S X WANG Z H IRINA S N | 2007 | IntJ FoodSciTech2007，42，1： | 1 |
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