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| 1 | Comparison of split-dosing vs non-split(morning) dosing regimen for assessment of quality of bowel preparation for colonoscopy显示文摘AIM: To compare(using the Ottawa Bowel Preparation Scale) the efficacy of split-dose vs morning administration of polyethylene glycol solution for colon cleansing in patients undergoing colonoscopy, and to assess the optimal preparation-to-colonoscopy interval.METHODS: Single-centre, prospective, randomized, investigator-blind stud in an academic tertiarycare centre. Two hundred patients requiring elective colonoscopy were assigned to receive one of the two preparation regimens(split vs morning) prior to colonoscopy. Main outcome measurements were bowel preparation quality and patient tolerability.RESULTS: Split-dose regimen resulted in better bowel preparation compared to morning regimen [Ottawascore mean 5.52(SD 1.23) vs 6.02(1.34); P = 0.017]. On subgroup analysis, for afternoon procedures, both the preparations were equally effective(P = 0.756). There was no difference in tolerability and compliance between the two regimens.CONCLUSION: Overall, previous evening- same morning split-dosing regimen results in better bowel cleansing for colonoscopy compared to morning preparation. For afternoon procedures, both schedules are equally effective; morning preparation may be more convenient to the patient. | Hardik Shah Devendra Desai Hrishikesh Samant Sandeep Davavala Anand Joshi Tarun Gupta Philip Abraham | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，12： | 8 |
| 2 | 搅拌摩擦对接焊6061铝合金的高周疲劳行为(英文)显示文摘对6061铝合金进行搅拌摩擦对接焊,其焊接工艺参数为:旋转速度600、800、1000、1200 r/min,前进速度80、100 mm/min,探针插入深度1.85 mm。基于搅拌摩擦焊参数计算得到的能量输入结果表明,在输入能量为196~405 kJ的情况下,接头在297~354 kJ的输入能量范围内有最大的抗拉强度。在不同的应力比(R=0.5,0.3,0.1,-0.3,-0.5)下,将高强度、低强度2种焊接头进行疲劳测试。结果表明,对于这2种焊接头,显微组织特征明显影响其疲劳性能,比如搅拌区、热力影响区(TMAZ)和热影响区。从接头的显微组织、裂纹扩展路径和断裂表面观察等方面对其疲劳强度进行讨论。 | Hrishikesh DAS Debayan CHAKRABORTY Tapan KUMAR PAL | 2014 | Transactions of Nonferrous Metals Society of China2014，24，3： | 7 |
| 3 | Cholestatic liver diseases:An era of emerging therapies显示文摘Recently the field of cholestasis has expanded enormously reflecting an improved understanding of the molecular mechanisms underlying bile secretion and its perturbation in chronic cholestatic disease. Novel anti-cholestatic therapeutic options have been developed for patients not favorably responding to ursodeoxycholic acid (UDCA), the current standard treatment for cholestatic liver disease. Important novel treatment targets now also include nuclear receptors involved in bile acid (BA) homoeostasis like farnesoid X receptor and G proteincoupled receptors e.g., the G-protein-coupled BA receptor “transmembrane G coupled receptor 5”. Fibroblast growth factor-19 and enterohepatic BA transporters also deserve attention as additional drug targets as does the potential treatment agent norUDCA. In this review, we discuss recent and future promising therapeutic agents and their potential molecular mechanisms in cholestatic liver disorders. | Hrishikesh Samant Wuttiporn Manatsathit David Dies Hosein Shokouh-Amiri Gazi Zibari Moheb Boktor Jonathan Steve Alexander | 2019 | World Journal of Clinical Cases2019，7，13： | 6 |
| 4 | Microcellular injection molding process for producing lightweight thermoplastic polyurethane with customizable properties显示文摘 | Thomas ELLINGHAM Hrishikesh KHARBAS Mihai MANITIU Guenter SCHOLZ Lih-Sheng TURNG | 2018 | Frontiers of Mechanical Engineering2018，13，1： | 2 |
| 5 | Efficacy and safety of standard and anti-reflux self-expanding metal stent: A systematic review and meta-analysis of randomized controlled trials显示文摘BACKGROUND Self-expanding metal stents are the main palliative treatment modality for unresectable esophageal cancer. Gastroesophageal reflux is a common adverse outcome after placement of esophageal stent for cancer involving the gastroesophageal junction and the gastric cardia. Anti-reflux stents with valve have been designed to prevent the acid reflux. The superiority of anti-reflux stent over standard stent in preventing gastroesophageal reflux has not been established well. This study compares the anti-reflux stent and the standard stent in terms of their efficacy to prevent acid reflux.AIM To compare the standard and the anti-reflux stents in terms of their efficacy,safety, and complications.METHODS The meta-analysis included 8 randomized clinical trials(RCTs) to compare pooled outcomes of total 395 patients. Primary outcomes include improvement in reflux symptoms and dysphagia score. Secondary outcomes include complications of stent migration, occlusion, and bleeding.RESULTS A total of eight RCTs were included in the meta-analysis. Compared to the standard stent, the anti-reflux stent showed a trend towards reduction in the dysphagia score without reaching a statistical significance [Standardized mean difference(SMD):-0.33(-0.71, 0.05); P = 0.09, I2: 37%]. There was no statistical difference in the gastrointestinal reflux(GER) scores between the two types of stents [SMD:-0.17(-0.78, 0.45); P = 0.008, I2: 74%]. Compared to standard stent,anti-reflux stent showed no difference in the risk of stent migration [OR: 1.37(0.66, 2.83); P = 0.40, I2: 0 %], bleeding [OR: 1.43(0.40, 5.13); P = 0.59, I2: 0 %], and obstruction [OR: 1.66(0.60, 4.60); P = 0.33, I2: 0 %].CONCLUSION Traditional self-expanding standard esophageal stent and anti-reflux stent with valve are similar in terms of outcomes and complications. | Sudha Pandit Hrishikesh Samant James Morris Steven J Alexander | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 2 |
| 6 | Probabilistic Demand Model and Performance Based Fragility Estimates for Rc Column Subject to Vehicle Collision显示文摘 | Hrishikesh Sharma Paolo Cardoni Stefan Hurlebaus | 2014 | Engineering Structures2014，74，： | 1 |
| 7 | lntracluster correlation adjustments to maintain power in cluster trials for binary outcomes显示文摘 | Hrishikesh Chakraborty Janet Moore Tyler D Hartwell | 2009 | Contemp Clin Trials2009，30，5： | 1 |
| 8 | Solid phase extraction, preconcetraction and sequential separation of U ( VI ), Th ( IV ),La(III) and Ce(III) by Octa-O-met hoxy resorcin arene based Amberlite XAD -4 chelating resin 显示文摘 | Keyur D Bhatt Disha J Vyas Hrishikesh S Gupte | 2014 | World Journal of Analy-tical Chemistry2014，2，： | 1 |
| 9 | A New Combination Rule for Conflict Problem of Dempster-Shafer Evidence Theory 显示文摘 | TAZID Ali PALASH Dutta HRISHIKESH Boru- ah | 2012 | International Journal of Energy Information and Communications2012，3，1： | 1 |
| 10 | Variation of physiological and antioxidative responses in tea cultivars subjected to ele- vated water stress followed by rehydration recovery显示文摘 | Hrishikesh U Sanjib K P Biman K D | 2008 | Acta Physiologiae Plantarum2008，30，： | 1 |
| 11 | Angiotensin II sustains brain inflammation in mice via TGF-[Beta]显示文摘 | Lanz Tobias V Ding Zhaoqing Ho Peggy P Luo Jian Agrawal Ankur N Srinagesh Hrishikesh Axtell Robert Zhang Hui Platten Michael Wyss-Coray Tony Steinman Lawrence | 2010 | Journal of Clinical Investigation2010，，8： | 1 |
| 12 | Variation of physiological and antioxidative responses in tea cultivars subjected to ele-vated water stress followed by rehydration recovery显示文摘 | Hrishikesh U Sanjib K P Biman K D | | 0，，： | 1 |
| 13 | Tensile testing of materials at high temperatures above 1 700℃ with in situ synchrotron X-ray miero-tomography 显示文摘 | Abdel H Hrishikesh A B James R N | 2014 | Review of Scientif- ic Instruments2014，85，08： | 1 |
| 14 | Effects of Nano - Fillers and Process Conditions on the Micrestrueture and Mechanical Properties of Mierecellular Injection Molded Polyamide Nanocomposites 显示文摘 | Hrishikesh Kharhas Paul Nelson Mingjun Yuan Shaoqin Gong Lib- sheng Tumg | 2003 | Polymer Composites2003，24，： | 1 |
| 15 | DRP: An Efficient Directional Routing Protocol for Mobile hd Hoc Networks显示文摘 | Hrishikesh Gossain Tarun Joshi Carlos De Morais Cordeiro | 2006 | IEEE TRANSACTIONS ON PARALLEL AND DISTRIBUTED SYSTEMS2006，17，12： | 1 |
| 16 | Human capital and economic growth:evidence from developing countries显示文摘 | Hrishikesh D V Surendra K K | 2007 | The American Economist2007，51，1： | 1 |
| 17 | Effects of nanofillers and process conditions on the microstructure and mechnical properties of microcellular injection molded polyamide nanocomposites 显示文摘 | Hrishikesh K Paul N Mingjun Y | 2003 | Polymer Compsoites2003，24，6： | 1 |
| 18 | Thermalconductivities of naked and monolayer protected metal nanoparticlebased nanofluids: manifestation of a nomalous enhancement andchemical effects显示文摘 | Hrishikesh E Patel Sarit K Das T Sundararajanl | 2003 | Applied Physics Letter2003，83，14： | 1 |
| 19 | Case report: aneurysmal bone cyst of the ethmoid bone显示文摘 | Hrishikesh KA Narlawar RS Deasi SB | 2002 | Br J Radiot2002，75，899： | 1 |
| 20 | Effect of process conditions on the weld line strength and microcellular injection molded parts显示文摘 | Turng L S Hrishikesh K | 2003 | Polymer Engineering Sci2003，43，1： | 1 |
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