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| 1 | Gastric emptying, postprandial blood pressure, glycaemia and splanchnic flow in Parkinson's disease显示文摘AIM: To determine gastric emptying, blood pressure, mesenteric artery blood flow, and blood glucose responses to oral glucose in Parkinson's disease. METHODS: Twenty-one subjects(13 M, 8 F; age 64.2 ± 1.6 years) with mild to moderate Parkinson's disease(Hoehn and Yahr score 1.4 ± 0.1, duration of known disease 6.3 ± 0.9 years) consumed a 75 g glucose drink, labelled with 20 MBq 99mTc-calcium phytate. Gastric emptying was quantified with scintigraphy, blood pressure and heart rate with an automated device, superior mesenteric artery blood flow by Doppler ultrasonography and blood glucose byglucometer for 180 min. Autonomic nerve function was evaluated with cardiovascular reflex tests and upper gastrointestinal symptoms by questionnaire. RESULTS: The mean gastric half-emptying time was 106 ± 9.1 min, gastric emptying was abnormally delayed in 3 subjects(14%). Systolic and diastolic blood pressure fell(P < 0.001) and mesenteric blood flow and blood glucose(P < 0.001 for both) increased, following the drink. Three subjects(14%) had definite autonomic neuropathy and 8(38%) had postprandial hypotension. There were no significant relationships between changes in blood pressure, heart rate or mesenteric artery blood flow with gastric emptying. Gastric emptying was related to the score for autonomic nerve function(R = 0.55, P < 0.01). There was an inverse relationship between the blood glucose at t = 30 min(R =-0.52, P < 0.05), while the blood glucose at t = 180 min was related directly(R = 0.49, P < 0.05), with gastric emptying. CONCLUSION: In mild to moderate Parkinson's disease, gastric emptying is related to autonomic dysfunction and a determinant of the glycaemic response to oral glucose. | Laurence G Trahair Thomas E Kimber Katerina Flabouris Michael Horowitz Karen L Jones | 2016 | World Journal of Gastroenterology2016，22，20： | 5 |
| 2 | Variation in the prothrombin time ratio during oral anticoagulation显示文摘 | Horowitz G | 1994 | N Engl J Med1994，330，： | 1 |
| 3 | Quasinormal modes of AdS black holes and the approach to thermal equilibrium显示文摘 | HOROWITZ G T HUBENY V E | 2000 | Phys Rev D2000，62，02： | 1 |
| 4 | Endometriosis in adolescence: along- term follow -up fecundability assessment 显示文摘 | Ventolini G Horowitz GM Long R | 2005 | Reprod Biol Endocrinol2005，96，3： | 1 |
| 5 | Sleep deprivation impairs long-term potentiation in rat hippocampal slices显示文摘 | Campbell I G Guinan M J Horowitz J M | | 0，，02： | 1 |
| 6 | Some applications of phasor measurements to adaptive protection显示文摘 | Thorp J S Phadke A G Horowitz S H | 1988 | IEEE Transactions on Power Systems1988，3，2： | 1 |
| 7 | Multicast-based lossinference with missing data显示文摘 | DUFFIELD N G HOROWITZ J TOWSLEY D | 2002 | IEEE Journal on Selected Areasin Communications2002，20，4： | 1 |
| 8 | Optimal freeway ramp metering using the asymmetric cell transmission model显示文摘 | Gomes G Horowitz R | 2006 | Transportation Research Part C2006，14，： | 1 |
| 9 | Retrospective analysis of hip frctures显示文摘 | Horowitz B G | 1966 | Surg Gynecol Obstet1966，，123： | 1 |
| 10 | Differen- tial expression and localization of de-novo synthesized endometfiotic haptoglobin in endometrium and endometfiotic lesions 显示文摘 | Sharpe-Timms K L Rieke E A Piva M Horowitz G M | 2000 | Hum Reprod2000，15，10： | 1 |
| 11 | Prolonged grief deisorder Psychometric validation of criteria proposed for DSM-V and ICD-11 显示文摘 | Prigerson H G Horowitz M J Jacobs S C | 2009 | PLoS Med2009，6，10： | 1 |
| 12 | Explicit Loss Inference in Multicast Tomography 显示文摘 | DUFFIELD N G HOROWITZ J LO PRESTI F | 2006 | IEEE Transactions on Information Theory2006，52，8： | 1 |
| 13 | Recent progress in polymers tbr clcctrolumincsccncc: microcavity devices and electrontransport polymers显示文摘 | WEAVER M S SAKAMATO Y HOROWITZ G | 1996 | Thin Solid Films1996，273，： | 1 |
| 14 | Surgical management of tumors involving the orbit显示文摘 | Weizman N Horowitz G Gil Z | 2013 | JAMA Otolaryngol Head Neck Surg2013，139，8： | 1 |
| 15 | Cocaethylene:effects on brain systems and behavior显示文摘 | Horowitz JM Torres G | 1999 | Addict Biol1999，4，2： | 1 |
| 16 | Multicast-based inference of network-internal delay distributions显示文摘 | Lo P F Duffield N G Horowitz J | 2002 | IEEE/ACM Transactions on Networking2002，10，6： | 1 |
| 17 | Taste and structure in phenolic glycosides显示文摘 | HOROWITZ R M BRUNO G | 1969 | J Agric Food Chern1969，17，4： | 1 |
| 18 | Syndrome of inappropriate antidiuretic hormone or arginine vasopressin secretion in patients fol- lowing neck dissection 显示文摘 | Zacay G Bedrin L Horowitz Z | 2002 | Laryngoscope2002，112，11： | 1 |
| 19 | Analysis of Potential Field Data in the Wavelet Domain显示文摘 | HORNBY P BOSCHETTI F HOROWITZ F G | 1999 | Geophysical Journal International1999，137，1： | 1 |
| 20 | No dy- namics in the extremal Kerr throat显示文摘 | Amsel A J Horowitz G T Marolf D | 2009 | JHEP2009，，9： | 1 |
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