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| 1 | Complete laparoscopic resection of the rectum using natural orifice specimen extraction显示文摘AIM: To investigate how complete laparoscopic anterior resection with natural orifice specimen extraction(NOSE), as a novel minimally invasive surgery, compares to conventional laparoscopic surgery.METHODS: Twenty patients who underwent complete laparoscopic anterior resection with NOSE and 50 patients who underwent laparoscopic assisted anterior resection by the conventional method between 2011 and 2012 were studied. Selection for complete laparoscopic anterior resection with NOSE was decided on the basis of tumor size, localization of the tumor, and body mass index. Outcomes related to surgery, including operation time, postoperative wound pain, hospital stay after surgery, the number of totally dissected lymph nodes, postoperative complications(suture failure and wound infection), and anal function, were reviewed retrospectively. Anal function was assessed at 3 and 6 mo after surgery using the Wexner fecal incontinence scoring system.RESULTS: Complete laparoscopic resection with NOSE was performed to completion in all 20 patients. There was no patient emergency that required conversion to conventional laparoscopic surgery or open surgery. The comparison between complete laparoscopic resection with NOSE and conventional laparoscopic surgery showed no significant differences in the maximal diameter of the tumor, number of totally dissected lymph nodes, bleeding volume, mean operation time, time to start of oral ingestion, postoperative hospital stay, and postoperative complications. On the other hand, with regard to pain after epidural anesthesia, the total usage of analgesia in this novel surgical technique was 1.85 ± 1.8 times, whereas it was 5.89 ± 2.86 in conventional laparoscopic surgery(P < 0.001). The postoperative pain period was 1.9 ± 1.9 d in this novel surgical technique, whereas it was 3.43 ± 1.41 d in conventional laparoscopic surgery(P < 0.004). In complete laparoscopic surgery with NOSE, the mean postoperative follow-up period was 20 mo(range: 12-30 mo). Neither local recurrence nor remote metastasis was observed during the follow-up period.CONCLUSION: Complete laparoscopic anterior resection using NOSE does not require any incision and has excellent cosmetic properties, with mitigated postoperative pain. | Masayuki Hisada Kenji Katsumata Tetsuo Ishizaki Masanobu Enomoto Takaaki Matsudo Kazuhiko Kasuya Akihiko Tsuchida | 2014 | World Journal of Gastroenterology2014，20，44： | 45 |
| 2 | Recovery of rare-earth metal neodymium from aqueous solutions by poly-γ-glutamic acid and its sodium salt as biosorbents:Effects of solution pH on neodymium recovery mechanisms显示文摘For recovery of metals from low-concentration sources, biosorption is one of promising technologies and poly-γ-glutamic acid(γ-PGA) has been known as a potential biosorbent for recovery of heavy metals from aqueous solutions. Effects of solution pH on recovery of rare-earth metal Nd are systematically examined to clarify mechanisms of Nd recovery by y-PGA and its sodium salt(y-PGANa). The recovery efficiency of Nd by y-PGA increases from 2.4 to 19.6% as pH increases from 2 to 4. Subsequently the Nd recovery efficiencies for y-PGA and y-PGANa remain almost constant in the range of pH from 4 to 7. For pH > 7 the increase in Nd recovery is significant and 100% recovery of Nd is achieved at pH 9. The pH dependency on Nd recovery by y-PGANa is similar to that by y-PGA. Contributions of adsorption and precipitation/coagulation to Nd recovery process are quantified. Whereas the adsorption dominates Nd recovery at lower pH(<~4), the precipitation/coagulation controls Nd recovery process for pH > 7. At higher pH, purple gel precipitates are observed. The maximum adsorption capacities for γ-PGA and yPGANa are 215 mg-Nd/(g-γ-PGA) at pH 4 and 305 mg-Nd/(g-y-PGANa) at pH 3, respectively. From the spectra of FT-IR and XPS, the biosorption of Nd onto y-PGA and y-PGANa via electrostatic interaction with carboxylate anions at pH 3 is verified. The Nd complexation with amide and carboxylate anion groups on γ-PGA and γ-PGANa may also contribute to the Nd recovery. The biosorption isotherms for Nd recovery by γ-PGA and γ-PGANa can be satisfactorily fitted by the Langmuir model. The thermodynamic studies suggest that the biosorptions of Nd by γ-PGA and γ-PGANa are endothermic. The utilization of γ-PGA and γ-PGANa as potential and eco-friendly biosorbents for the highly effective recovery of Nd from aqueous solution is confirmed. | Misaki Hisada Yoshinori Kawase | 2018 | Journal of Rare Earths2018，36，5： | 5 |
| 3 | Rehabilitation of concrete cracks by electrodeposition显示文摘 | Nobuaki Otsuki Makoto Hisada Ryu Jae-Suk | 1999 | Concrete International1999，21，6： | 2 |
| 4 | Activation of transcription factor NF-κB in experimental glomerulonephritis in rats显示文摘 | Sakurai H Hisada Y Ueno M | 1996 | Biochim Biophys Acta1996，1316，2： | 1 |
| 5 | Angiotensin Ⅱ plays a pathogenic role in immune-mediated renal injury in mice显示文摘 | Sugaya T Yamanouchi M | 1999 | J Clin Invest1999，103，： | 1 |
| 6 | An investigation of the morphological changes in poly (ethylene terephthalate) fiber treated with supercritical carbon diox- ide under various conditions 显示文摘 | HIROGAKI K TABATA I HISADA K | 2006 | J Supercrit Fluids2006，38，3： | 1 |
| 7 | Cardiovascular safety of the dipetidyl peptidase‐4 inhibitor alogliptin in type 2 diabetes mellitus显示文摘 | W. B. White R. Pratley P. Fleck M. Munsaka M. Hisada C. Wilson V. Menon | 2013 | Diabetes Obes Metab2013，，： | 1 |
| 8 | P- T-fluid Evolution in the Mahalapye Complex, Limpopo High-grade Terrane, Eastern Botswana 显示文摘 | HISADA K PERCHUK L L GERYA T V | 2005 | Journal of Metamorphic Geology2005，23，5： | 1 |
| 9 | An experimental study on the fluidity of antiwashout concrete显示文摘 | Otsuki N Hisada M Nagataki S | 1996 | ACI Materials Journal1996，93，1： | 1 |
| 10 | Activation of transcription factor NF-KB in experimental glomerulonephritis in rats显示文摘 | Sakurai H Hisada Y UenoM Suqiura M Kawashima K Suqita T | 1996 | Biochim Biophys Acta1996，1316，2： | 1 |
| 11 | Potent antitumor activity of interleukin-27显示文摘 | Hisada M Kamiya S Fujita K | 2004 | Cancer Res2004，64，3： | 1 |
| 12 | Helicobacter pylori associated global gastric cancer burden显示文摘 | Mbulaiteye SM Hisada M E1-Omar EM | 2009 | Front Biosci2009，1，14： | 1 |
| 13 | 13C NMR analysis of symplocosin and (+)-epipinoresinol glucoside显示文摘 | Chiba M Hisada S Nishibe S 1980 | 1980 | Phytochemistry1980，19，2： | 1 |
| 14 | A theoretical omega-square model considering the spatial variation in slip and rupture velocity 显示文摘 | Hisada Y | 2000 | Bulletin of the Seismological Society of America2000，90，： | 1 |
| 15 | Resolvin El as a novel agent for the treatment of asthma 显示文摘 | Hisada T Ishizuka T Aoki H | 2009 | Expert Opin Ther Targets2009，13，5： | 1 |
| 16 | Glutathione redox regulates airway hyperresponsiveness and airway inflammation in mice显示文摘 | Koike Y Hisada T Utsugi M | | 0，，03： | 1 |
| 17 | A theoretical omega-square model considering the spatial variation in slip and rupture velocity, part 2 : Case for a two dimensional souree model显示文摘 | Hisada Y | 2001 | Bulletin of the Seismological Society of America2001，91，： | 1 |
| 18 | Depositional and compositional controls on sandstone diagenesis, the Tetori Group(Middle Jurassic-Early Cretaceous), central Japan显示文摘 | Kim J C Lee Y I Hisada K | 2007 | Sedimentary Geology2007，195，： | 1 |
| 19 | Potent antitumor activity of inter-leukin-27显示文摘 | Hisada M Kamiya S Fujita K | | 0，，3： | 1 |
| 20 | Theoretical evaluation of diffusion coefficient of chloride ion in mortar from moility显示文摘 | OTSUKI N HISADA M OTANI T | 1999 | ACI Materials Journal1999，96，6： | 1 |
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