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| 1 | The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53显示文摘 | Hiroaki Higashitsuji Hisako Higashitsuji Katsuhiko Itoh Toshiharu Sakurai Toshikazu Nagao Haruhiko Sumitomo Tomoko Masuda Simon Dawson Yutaka Shimada R. John Mayer Jun Fujita | 2005 | Cancer Cell2005，，： | 2 |
| 2 | Cloning and characterization of human CIRP (cold-inducible RNA- binding protein) cDNA and chromosomal assignment of the gene显示文摘 | Nishiyama H Higashitsuji H Yokoi H | 1997 | Gene1997，204，12： | 1 |
| 3 | Cloning and characterization of human CIRP ( cold - inducible RNA - binding protein) cDNA and chromosomal assignment of the gene显示文摘 | NISHIYAMA H HIGASHITSUJI H YOKOI H | 1997 | Gene1997，204，12： | 1 |
| 4 | Reduced stability of retinoblastoma protein by gankyrin,an oncogenic ankyrin-repeat protein overexpressed in hepatomas显示文摘 | Higashitsuji H Itoh K Nagao T | 2000 | Nat Med2000，6，1： | 1 |
| 5 | A cleaved form of MAGE- A4 binds to Miz-1 and induces apoptosis in human cells显示文摘 | Sakurai T Itoh K Higashitsuji H | 2004 | J Bi- d Chem2004，279，15： | 1 |
| 6 | MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity显示文摘 | Nagao T Higashitsuji H Nonoguchi K | 2003 | J Biol Chem2003，278，10： | 1 |
| 7 | The crystal structure of gankyrin,an oncoprotein found in complexes with cyclin-dependent kinase 4,a 19S proteasomal ATPase regulator,and the tumor suppressors Rb and p53显示文摘 | Krzywda S Brzozowski A M Higashitsuji H | 2004 | J Boil chem2004，279，2： | 1 |
| 8 | The crys- tal structure of gankyrin,an oncoprotein found in com- plexes with cyclin-dependent kinase 4,a 19 S proteaso- mal ATPase regulator,and the tumor suppressors Rb and p53显示文摘 | Krzywda S Brzozowski AM Higashitsuji H | 2004 | J Biol Chem2004，279，2： | 1 |
| 9 | Reduced stability of retino- blastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas显示文摘 | Higashitsuji H Itoh K Nagao T | 2000 | Nat Med2000，6，1： | 1 |
| 10 | The crystal structure of gankyrin, an oncoprotein found in complexes with eye- lin-dependent kinase 4, a 19 S pruteasomal ATPase regulator, and the tumor suppressors Rb and p53 显示文摘 | Krzywda S Brzozowski AM Higashitsuji H | 2004 | J Biol Chem2004，279，2： | 1 |
| 11 | The onco- protein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53显示文摘 | Higashitsuji H Higashitsuji H Itoh K | 2005 | Cancer Cell2005，8，1： | 1 |
| 12 | The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of pS3显示文摘 | Higashitsuji H Higashitsuji H Itoh K | 2005 | Cancer Cell2005，，： | 1 |
| 13 | Apg-2 has a chap- erone-like activity similar to HspllO and is overexpressed in hepatocellular carcinomas 显示文摘 | Gotoh K Nonoguchi K Higashitsuji H | 2004 | FEBS Left2004，560，13： | 1 |
| 14 | The oneoprotein gankyrin negatively regulates both p53 and RB by enhancing preteasomal degradation显示文摘 | Higashitsuji H Liu Y Mayer R J | 2005 | Cell Cycle2005，4，10： | 1 |
| 15 | The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53 显示文摘 | Higashitsuji H Higashitsuji H Itoh K | 2005 | Cancer Cell2005，8，1： | 1 |
| 16 | Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice显示文摘 | Tomoko Masuda Katsuhiko Itoh Hiroaki Higashitsuji Hisako Higashitsuji Noa Nakazawa Toshiharu Sakurai Yu Liu Hiromu Tokuchi Takanori Fujita Yan Zhao Hiroyuki Nishiyama Takashi Tanaka Manabu Fukumoto Masahito Ikawa Masaru Okabe Jun Fujita | 2012 | Proceedings of the National Academy of Sciences2012，，27： | 1 |
| 17 | The Oncoprotein Gankyrin Negatively Regulates Both p53 and RB by Enhancing Proteasomal Degradation显示文摘 | Hiroaki Higashitsuji Yu Liu R. John Mayer Jun Fujita | 2005 | Cell Cycle2005，，10： | 1 |
| 18 | Cirp protects against tumor necrosis factor-α-induced apoptosis via activation of extracellular signal-regulated kinase显示文摘 | Toshiharu Sakurai Katsuhiko Itoh Hiroaki Higashitsuji Kohsuke Nonoguchi Yu Liu Hirohiko Watanabe Tadasu Nakano Manabu Fukumoto Tsutomu Chiba Jun Fujita | 2006 | BBA - Molecular Cell Research2006，，3： | 1 |
| 19 | Apg-2 has a chaperonelike activity similar to Hsp110 and is overexpressed in hepatocellular carcinomas 显示文摘 | Gotoh K Nonoguchi K Higashitsuji H | 2004 | FEBS Letters2004，560，13： | 1 |
| 20 | MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity 显示文摘 | Nagao T Higashitsuji H Nonoguchi K | 2003 | J Biol Chem2003，278，10： | 1 |
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