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| 1 | Cytomegalovirus frequency in neonatal intrahepatic cholestasis determined by serology, histology, immunohistochemistry and PCR显示文摘AIM: To determine cytomegalovirus (CMV) frequency in neonatal intrahepatic cholestasis by serology, histological revision (searching for cytomegalic cells), immunohistochemistry, and polymerase chain reaction (PCR), and to verify the relationships among these methods.METHODS: The study comprised 101 non-consecutive infants submitted for hepatic biopsy between March 1982 and December 2005. Serological results were obtained from the patient's f iles and the other methods were performed on paraffin-embedded liver samples from hepatic biopsies. The following statistical measures were calculated: frequency, sensibility, specif ic positive predictive value, negative predictive value, and accuracy.RESULTS: The frequencies of positive results were as follows: serology, 7/64 (11%); histological revision, 0/84; immunohistochemistry, 1/44 (2%), and PCR, 6/77 (8%). Only one patient had positive immunohistochemical fi ndings and a positive PCR. The following statistical measures were calculated between PCR and serology: sensitivity, 33.3%; specificity, 88.89%; positive predictive value, 28.57%; negative predictive value, 90.91%; and accuracy, 82.35%. CONCLUSION: The frequency of positive CMV varied among the tests. Serology presented the highest positive frequency. When compared to PCR, the sensitivity and positive predictive value of serology were low. | Maria Angela Bellomo-Brandao Paula D Andrade Sandra CB Costa Cecilia AF Escanhoela Jose Vassallo Gilda Porta Adriana MA De Tommaso Gabriel Hessel | 2009 | World Journal of Gastroenterology2009，15，27： | 8 |
| 2 | Urinary biomarkers for prostate cancer: a review显示文摘尽管测试的前列腺特定的抗原(PSA ) 无疑增加了的浆液的平淡的使用前列腺癌症(PCa ) 察觉,它的主要缺点之一是它特性的缺乏。作为后果,许多人为懒惰的瘤经历不必要的活体检视或治疗。PCa 特定的标记为疾病和一个前列腺瘤的攻击性的预言的早察觉被需要。因为 PCa 是异构的疾病,瘤标记的一块面板为更精确的诊断是基本的。几 biomarkers 由于他们为在组织的疾病的特性是有希望的。然而,织物是象一个可能的屏蔽工具不合适。因为尿能容易以一种非侵略的方式被获得,它是为测试的 biomarker 的有希望的底层。这篇文章为在尿的 PCa 的非侵略的测试考察 biomarkers。 | Daphne Hessels Jack A Schalken | 2013 | Asian Journal of Andrology2013，15，3： | 5 |
| 3 | Plasma-electrochemical synthesis of europium doped cerium oxide nanoparticles显示文摘In the present study,a plasma-electrochemical method was demonstrated for the synthesis of europium doped ceria nanoparticles.Ce(NO3)3· 6H2O and Eu(NO3)3·5H2O were used as the starting materials and being dissolved in the distilled water as the electrolyte solution.The plasma-liquid interaction process was in-situ investigated by an optical emission spectroscopy,and the obtained products were characterized by complementary analytical methods.Results showed that crystalline cubic CeO2:Eu3+ nanoparticles were successfully obtained,with a particle size in the range from 30 to 60 nm.The crystal structure didn't change during the calcination at a temperature from 400℃ to 1000℃,with the average erystallite size being estimated to be 52 nm at 1000℃.Eu3+ ions were shown to be effectively and uniformly doped into the CeO2 lattices.As a result,the obtained nanophosphors emit apparent red color under the UV irradiation,which can be easily observed by naked eye.The photoluminescence spectrum further proves the downshift behavior of the obtained products,where characteristic 5Do → 7F1,2,3 transitions of Eu3+ ions had been detected.Due to the simple,flexible and environmental friendly process,this plasma-electrochemical method should have great potential for the synthesis of a series of nanophosphors,especially for bio-application purpose. | Liangliang Lin Xintong Ma Sirui Li Marly Wouters Volker Hessel | 2019 | Frontiers of Chemical Science and Engineering2019，13，3： | 3 |
| 4 | Cabozantinib in Progressive Medullary Thyroid Cancer显示文摘 | Rossella Elisei Martin J. Schlumberger Stefan P. Müller Patrick Sch?ffski Marcia S. Brose Manisha H. Shah Lisa Licitra Barbara Jarzab Viktor Medvedev Michael C. Kreissl Bruno Niederle Ezra E.W. Cohen Lori J. Wirth Haythem Ali Colin Hessel Yifah Yaron Doug | 2013 | Journal of Clinical Oncology2013，，29： | 3 |
| 5 | Mixers with Microstructured Foils for Chemical Production Purposes显示文摘约翰威立出版公司是世界知名的出版集团,出版、发行许多著名学术、技术期刊和书籍。《化工进展》编辑部从2005年第5期起,与新加坡约翰威立股份有限公司合作,不定期刊登其出版、发行的知名化工期刊的原版文章。欢迎读者提出宝贵意见。 | Bernd Werner Volker Hessel Patrick Lb | 2005 | 化工进展2005，24，5： | 3 |
| 6 | Heating and Cooling Performance of Earth-Tube Heat Exchanger in a Mechanical Ventilated Farrowing House显示文摘 | E. F. Hessel C. Zurhake H. F. Van den Weghe | 2011 | Journal of Agricultural Science and Technology(A)2011，1，2X： | 3 |
| 7 | DD3 PCA3 -based Molecular Urine Analysis for the Diagnosis of Prostate Cancer显示文摘 | Daphne Hessels Jacqueline M.T. Klein Gunnewiek Inge van Oort Herbert F.M. Karthaus Geert J.L. van Leenders Bianca van Balken Lambertus A. Kiemeney J.Alfred Witjes Jack A. Schalken | 2003 | European Urology2003，，1： | 2 |
| 8 | Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists显示文摘 | KANZLER H BARRAT FJ HESSEL EM | 2007 | Nat Med2007，13，5： | 1 |
| 9 | Optimal perfusion during cardiopulmonary bypass: an evidence based approach 显示文摘 | Murphy GS Hessel EA 2nd Groom RC | 2009 | Anesth Analg2009，108，5： | 1 |
| 10 | DD3 (PCA3)-based molecular urine analysis for the diagosis of prostate cancer显示文摘 | Hessels D klein Gunnewiek JMT Van Oort I | 2003 | Eur Urol2003，44，1： | 1 |
| 11 | Patellar dislocation:cylinder cast,splint or brace:An evidence-based review of the liter-ature显示文摘 | van Gemert JP de Vree LM Hessels RA | 2012 | Int J Emerg Med2012，5，1： | 1 |
| 12 | Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A显示文摘 | Kiefer C Hessel S Lampert J M etal | 2001 | Journal of Biological Chemistry2001，17，14： | 1 |
| 13 | Passive micromixer for applications in the microreactor andμTAS fields显示文摘 | HARDT S DRESE K S HESSEL F | 2005 | Microfluidics and Nanofluidics2005，1，2： | 1 |
| 14 | The occurrence of polyeylie sesqui-, tri-, and oligoterpe- noids derived from a resinous polymeric eadinene in crude oils from southeast Asia 显示文摘 | Van Aarssen B G K Hessels J K C Abbink O A De Leeuw J W | 1992 | Geoehim Cosmoehim Aeta1992，56，3： | 1 |
| 15 | DD3(PCA3)-based molecular urine analysis for the diagnosis of prostate cancer显示文摘 | HESSELS D KLEIN GUNNEWIEK J M AN OORTI | 2003 | Eur Urol2003，44，： | 1 |
| 16 | The time -resolved fluorescencc- based PCA3 test on urinary sediments after digital rectal examination; a Dutch multicenter validation of the diagnostic performance 显示文摘 | Van Gils MP Hessels D van Hooij O | 2007 | Clin Cancer Res2007，13，： | 1 |
| 17 | Economic evaluation and survial analysis of immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy 显示文摘 | Hessel FP Wegner C Muller J | 2004 | Eur J Health Econom2004，5，1： | 1 |
| 18 | Chemistry in microstructured reactors显示文摘 | Jahnisch K Hessel V Lowe H | 2004 | Angew Chem Int Ed2004，43，： | 1 |
| 19 | Interferon-gamma release assays and childhood tuberculosis: systematic review and recta-analysis显示文摘 | Mandalakas A M Detjen A K Hesseling A C | 2011 | The International Journal of Tuberculosis and Lung Disease2011，15，8： | 1 |
| 20 | Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor 显示文摘 | Lee JE Fusco ML Hessell AJ et O1 | 2008 | Nature2008，454，7201： | 1 |
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