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| 1 | Pre-and postoperative systemic hemodynamic evaluation in patients subjected to esophagogastric devascularization plus splenectomy and distal splenorenal shunt:A comparative study in schistomomal portal hypertension显示文摘AIM: To investigate the systemic hemodynamic effects of two surgical procedures largely employed for treatment of schistosomal portal hypertension. METHODS: Thirty-six patients undergoing elective surgical treatment of portal hypertension due to hepatosplenic mansonic schistosomiasis were prospectively evaluated. All patients were subjected to preoperative pulmonary artery catheterization; 17 were submitted to esophagogastric devascularization and splenectomy (EGDS) and 19 to distal splenorenal shunt (DSRS). The systemic hemodynamic assessment was repeated 4 d after the surgical procedure. RESULTS: Preoperative evaluation revealed (mean ± SD) an increased cardiac index (4.78 ± 1.13 L/min per m2),associated with a reduction in systemic vascular resistance index (1457 ± 380.7 dynes.s/cm5.m2). The mean pulmonary artery pressure (18 ± 5.1 mmHg) as well as the right atrial pressure (7.9 ± 2.5 mmHg) were increased,while the pulmonary vascular resistance index (133 ± 62 dynes.s/cm5.m2) was decreased. Four days after EGDS,a significant reduction in cardiac index (3.80 ± 0.4 L/min per m2,P < 0.001) and increase in systemic vascular resistance index (1901.4 ± 330.2 dynes.s/cm5. m2,P < 0.001) toward normal levels were observed. There was also a significant reduction in pulmonary artery pressure (12.65 ± 4.7 mmHg,P < 0.001) and no significant changes in the pulmonary vascular resistance index (141.6 ± 102.9 dynes.s/cm5.m2). Four days after DSRS,a non-significant increase in cardiac index (5.2 ± 0.76 L/min per m2) and systemic vascular resistance index (1389 ± 311 dynes.s/cm5.m2) was observed. There was also a non-significant increase in pulmonary artery pressure (19.84 ± 5.2 mmHg),right cardiac work index (1.38 ± 0.4 kg.m/m2) and right ventricular systolic work index (16.3 ± 6.3 g.m/m2),without significant changes in the pulmonary vascular resistance index (139.7 ± 67.8 dynes.s/cm5.m2). CONCLUSION: The hyperdynamic circulatory state observed in mansonic schistosomiasis was corrected by EGDS,but was maintained in patients who underwent DSRS. Similarly,the elevated mean pulmonary artery pressure was corrected after EGDS and maintained after DSRS. EGDS seems to be the most physiologic surgery for patients with schistosomal portal hypertension. | Roberto de Cleva Paulo Herman Luis Augusto Carneiro D’albuquerque Vincenzo Pugliese Orlando Luis Santarem William Abro Saad | 2007 | World Journal of Gastroenterology2007，13，41： | 9 |
| 2 | Absence of CNTNAP2 leads to epilepsy,neuronal migration abnormalities,and core autism-related deficits显示文摘 | Pe(n)agarikano O Abrahams BS Herman EI | | 0，，01： | 1 |
| 3 | Follow up and outcome of pregnancy located in a previous caesarean section scar显示文摘 | Weinraub Z Avrech O | 1995 | Br J Obstet Gynaecol1995，102，8： | 1 |
| 4 | Follow up and outcome of isthmic pregnancy located in a previous caesarean sectopm Scar显示文摘 | Herman A Weinraub Z Avrech O | 1995 | Br J Obstet Gynecol1995，102，10： | 1 |
| 5 | MPP+ induces the endoplasmic reticulum stress response in rabbit brain involving activation of the ATF-6 and NF-κB signaling pathways显示文摘 | Ghribi O Herman MM Pramoonjago P | 2003 | J Neuropathol Exp Neurol2003，62，： | 1 |
| 6 | Sulfur and iron speciation in surface sediments along the northwestern margin of the Black Sea显示文摘 | Wijsman J W Herman P M J B(o)ttcher M E | 2001 | Marine Chemistry2001，74，： | 1 |
| 7 | Mechanisms of aluminum-induced neurodegeneration in animals:Implications for Alzheimer's disease显示文摘 | Savory J Herman MM Ghribi O | 2006 | J Alzheimers Dis2006，10，23： | 1 |
| 8 | Mechanisms of a- luminum-induced neurodegeneration in animals: impli- cations for Alzheimer's disease显示文摘 | Savory J Herman M M Ghribi O | 2006 | J Alzheimers Dis2006，10，23： | 1 |
| 9 | Mechanisms of aluminum-in- duced neurodegeneration in animals: implications for Alzheimer's disease显示文摘 | Savory J Herman MM Ghribi O | 2006 | J Alzbeimers Dis2006，10，23： | 1 |
| 10 | Board practices of especially effective and less effective local nonProfit or ganizations显示文摘 | ROBERT D HERMAN DAVID O RENZ | 2000 | American Review of Public Administration2000，30，2： | 1 |
| 11 | Pyrite oxidation at circumneutral pH 显示文摘 | Moses C O Herman J S | 1991 | Geochim Cosmochim Acta1991，55，2： | 1 |
| 12 | Variability of sea ice deformation rates in the Arctic and their relationship with basin-scale wind forcing显示文摘 | Herman A Glowacki O | 2012 | The Cro- sphere2012，6，： | 1 |
| 13 | Abeta (1-42) and aluminum induce stress in endoplasimic reticular in rabbit hippocampus, involving nuclear translocation of gad 153 and NF- kappaB显示文摘 | Ghribi O Herman MM | 2001 | Brain Res Mol Brain Res2001，96，12： | 1 |
| 14 | Methylation-specific PCR:a novel PCR assay for methylation status of CpG islands显示文摘 | HERMAN J G GRAFF J R MY(O)H(A)NEN S | 1996 | Proc Natl Acad Sci U S A1996，93，18： | 1 |
| 15 | Aqueous pyrite oxidation by dissolved oxygen and by ferric iron 显示文摘 | Moses C O Nordstrom D K Herman J S | 1987 | Geochimica et Cosmochimica Acta1987，51，： | 1 |
| 16 | Ki67 as a biologic marker of basal cell carcinoma:a retrospective study显示文摘 | Karmer E Herman O Frand J | 2014 | Isr Med Assoc J2014，16，4： | 1 |
| 17 | The findings and se- quence of events leading to termination of pregnancy due to Down's syndrome-before and after the verge of viability: 10 years experi- ence at a single medical center 显示文摘 | Baruchin O Maymon R Herman A | 2012 | Harefuah2012，151，60： | 1 |
| 18 | The fundamental role of epigenet-ics in hematopoietic malignnancies显示文摘 | Galm O Herman JG Baylin SB | | 0，，01： | 1 |
| 19 | Effect of repeated lipopolysaccharide administration on tissue cytokine expression and hypothalamic-pituitary-adrenal axis activity in rats显示文摘 | Herman JP Jezava O | 2001 | J Neuroendocrinology2001，13，8： | 1 |
| 20 | Follow up and outcome of isthmic pregnancy located in a previous caesarean section scar显示文摘 | Herman A Weinraub Z Avrech O | 1995 | Br J Obstet Gynecol1995，102，： | 1 |
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