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| 1 | Challenges in diagnosing mesenteric ischemia显示文摘Early identification of acute mesenteric ischemia (AMI) is challenging. The wide variability in clinical presentation challenges providers to make an early accurate diagnosis. Despite major diagnostic and treatment advances over the past decades, mortality remains high. Arterial embolus and superior mesenteric artery thrombosis are common causes of AMI. Non-occlusive causes are less common, but vasculitis may be important, especially in younger people. Because of the unclear clinical presentation and non-specific laboratory findings, low clinical suspicion may lead to loss of valuable time. During this diagnostic delay, progression of ischemia to transmural bowel infarction with peritonitis and septicemia may further worsen patient outcomes. Several diagnostic modalities are used to assess possible AMI. Multi-detector row computed tomographic angiography is the current gold standard. Although computed tomographic angiography leads to an accurate diagnosis in many cases, early detection is a persistent problem. Because early diagnosis is vital to commence treatment, new diagnostic strategies are needed. A non-invasive simple biochemical test would be ideal to increase clinical suspicion of AMI and would improve patient selection for radiographic evaluation. Thus, AMI could be diagnosed earlier with follow-up computed tomographic angiography or high spatial magnetic resonance imaging. Experimental in vitro and in vivo studies show promise for alpha glutathione S transferase and intestinal fatty acid binding protein as markers for AMI. Future research must confirm the clinical utility of these biochemical markers in the diagnosis of mesenteric ischemia. | Teun C van den Heijkant Bart AC Aerts Joep A Teijink Wim A Buurman Misha DP Luyer | 2013 | World Journal of Gastroenterology2013，19，9： | 31 |
| 2 | Progression From Paroxysmal to Persistent Atrial Fibrillation显示文摘 | Cees B. de Vos Ron Pisters Robby Nieuwlaat Martin H. Prins Robert G. Tieleman Robert-Jan S. Coelen Antonius C. van den Heijkant Maurits A. Allessie Harry J.G.M. Crijns | 2010 | Journal of the American College of Cardiology2010，，8： | 4 |
| 3 | Presence and mechanism of knee articular cartilage degeneration after meniscal reconstruction in dogs显示文摘 | Van Tienen TG Heijkants RG de Groot JH | 2003 | Osteoarthritis Cartilage2003，11，1： | 1 |
| 4 | Randomized clinical trial of the effect of gum chewing on postoperative ileus and inflammation in colorectal surgery 显示文摘 | Van den Heijkant TC Costes LM van der Lee DG | 2015 | Br J Surg2015，102，3： | 1 |
| 5 | Bowen's disease:A six-year retrospective study of treatment with emphasis on resection margins显示文摘 | Westers-Attema A van den Heijkant F Lohman BG | 2014 | Acta Derm Venereol2014，94，4： | 1 |
| 6 | Replacement of the knee meniscus by a porous polymer implant:a study in dogs显示文摘 | Tienen T G Heijkants R G de Groot J H | 2006 | Am J Sports Med2006，34，1： | 1 |
| 7 | Replacement of the knee meniscus by a porous polymer implant - A study in dogs显示文摘 | TIENEN T G HEIJKANTS R G GROOT J H | 2006 | American Journal of Sports Medicine2006，34，1： | 1 |
| 8 | Randomized clinical trial of the effect of gum chewing on postoperative ileus and inflammation in eolorectal surgery显示文摘 | van den Heijkant TC Costes LM van der Lee DG | 2015 | Br J Surg2015，102，3： | 1 |
| 9 | Preparation of a polyurethane scaffold for tissue engineering made by a combination of salt leaching and freeze-drying of dioxane显示文摘 | HEIJKANTS R G J C Tienen T G GROOT J H | 2006 | Journal of Materials Science2006，41，8： | 1 |
| 10 | Polyurethane scaffold formation via a combination of salt leaching and thermally induced phase separation显示文摘 | Heijkants RGJC van Calck RV van Tienen TG | 2008 | J Biomed Mater Res2008，，： | 1 |
| 11 | Randomized clinical trial of the effect of gum chewing on postoperative ileus and inflammation in colorectal surgery显示文摘 | Van Den Heijkant TC Costes LM Van Der Lee DG | 2015 | Br J Surg2015，102，3： | 1 |
| 12 | Replacement of the knee meniscus by a porous polymer implant: a study in dogs显示文摘 | Tienen TG Heijkants RG Groot JH | 2006 | Am J Sports Med2006，34，： | 1 |
| 13 | Uncatalyzed synthesis, thermal and mechanical properties of polyurethanes based on poly( E - caprolactone) and 1,4-butane diisocyanate with uniform hard segment显示文摘 | Ralf G J C Heijkants Ralph V van Calck Tony G van Tienen | 2005 | Biomaterials2005，26，20： | 1 |
| 14 | Temperature - pro- grammed sulfiding of catalysts 显示文摘 | Arnoldy P Heijkant J A Bok G D D | 1985 | Journal of Catalysis1985，92，1： | 1 |
| 15 | Tissue ingrowth and degradution of two biodegradable porous polymers with different porosities and pore sizes显示文摘 | Van Tienen TG Heijkants RGJC Buma P | 2002 | Biomaterials2002，23，8： | 1 |
| 16 | Replacement of the knee meniscus by a porous polymer implant:a study in dogs显示文摘 | Tienen TG Heijkants RG de Groot JH | 2006 | Am J Sorts Med2006，34，： | 1 |
| 17 | Efficacy of bladder irrigation and surveillance program in prevention of urinary tract infections and bladder calculi in children with an ileocystoplasty and bladder neck repair显示文摘 | Van den Heijkant M Haider N Taylor C | 2011 | Pediatr Surg Int2011，27，7： | 1 |
| 18 | Temperature-Programmed Sulfiding of MoO3/A1203 Catalysts 显示文摘 | Arnoldy P van den Heijkant J A M de Bok G D | 1985 | JCatal1985，92，1： | 1 |
| 19 | Efficacy of bladder irrigation and surveillance program in prevention of u- rinary tract infections and bladder calculi in children with an ileocystoplasty and bladder neck repair显示文摘 | van den Heijkant M Haider N Taylor C | 2011 | Pediatr Surq Int2011，27，7： | 1 |
| 20 | Photodynamic therapy in bowenrs disease: influence of histological features and clinical characteristics on its suc- eess显示文摘 | Westers-Attema A Lohman BG Van Den Heijkant F | 2015 | Dermatology2015，230，1： | 1 |
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