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| 1 | Fe_3O_4@C nanoparticles as high-performance Fenton-like catalyst for dye decoloration显示文摘Water pollution has become serious environmental problem nowadays. Advanced oxidation processes(AOP) have been widely applied in water treatment.However, traditional Fenton reaction based on Fe2﹢-H2O2 system has obvious drawbacks, which limit its applications In this study, magnetic Fe3O4core-C shell nanoparticles(Fe3O4@C NPs) were prepared for the decoloration of methylene blue(MB) via the co-precipitation followed by the hydrothermal dehydrogenation of glucose. Fe3O4@C NPs showed high catalytic activity of the decoloration of MB through the decomposition of H2O2 in Fenton-like reactions. Fe3O4@C NPs had much higher activity than bare Fe3O4 cores, suggesting the coating of carbon enhanced the catalytic activity. The performance of Fe3O4@C NPs was better at lower pH and higher temperature, but was significantly inhibited in the presence of radical scavenger tertiary butanol. Fe3O4@C NPs could be magnetic separated and regenerated, and maintained with very good catalytic activity. The implication for the applications of Fe3O4@C NP-catalyzed Fenton-like reactions in water treatment was discussed. | Xiaoliang Zhang Manli He Jia-Hui Liu Rong Liao Lianqin Zhao Jingru Xie Ruijue Wang Sheng-Tao Yang Haifang Wang Yuanfang Liu | 2014 | Chinese Science Bulletin2014，59，27： | 8 |
| 2 | Containment of soft wall casing wrapped with Kevlar fabric显示文摘Aramid fabrics have been commonly used in the civil turbofan engine fan blade containment system for its excellent performance. To investigate the behavior and capability of soft wall containment casing, a series of fan blade released tests were conducted on the high-speed spin tester.The soft wall casing was fabricated by wrapping multiple layers of Kevlar49 plain woven fabric around a thin steel ring. Casings with different inner metal ring and outer fabric layers number were compared. The method of using the explicit dynamic software LS-DYNA to establish the finite element analysis model for the quantitative analysis of the containment process was developed and conducted. The simulation results are in good agreement with the test results. It is shown that the containment process of the soft wall casing can be divided into three impact stages. The casing with low-stiffness inner metal ring will get severe overall deformation and lose the structural integrity when it suffers the blade impact. Kevlar fabric layers will appear large bulge on outside surface and absorb the most impact dynamic energy of the high speed released fan blade. By summing up the results of the test and simulation, an empirical critical equation was derived to describe the relationship between the released blade dynamic energy and the Kevlar fabric thickness. | Zekan HE Haijun XUAN Conger BAI Manli SONG Zhuoshen ZHU | 2019 | Chinese Journal of Aeronautics2019，32，4： | 5 |
| 3 | Rapid isolation and immune profiling of SARS-CoV-2 specific memory B cell in convalescent COVID-19 patients via LIBRA-seq显示文摘B cell response plays a critical role against SARS-CoV-2 infection.However,little is known about the diversity and frequency of the paired SARS-CoV-2 antigen-specific BCR repertoire after SARS-CoV-2 infection.Here,we performed single-cell RNA sequencing and VDJ sequencing using the memory and plasma B cells isolated from five convalescent COVID-19 patients,and analyzed the spectrum and transcriptional heterogeneity of antibody immune responses.Via linking BCR to antigen specificity through sequencing(LIBRA-seq),we identified a distinct activated memory B cell subgroup(CD11c^(high) CD95^(high))had a higher proportion of SARS-CoV-2 antigen-labeled cells compared with memory B cells.Our results revealed the diversity of paired BCR repertoire and the non-stochastic pairing of SARS-CoV-2 antigen-specific immunoglobulin heavy and light chains after SARS-CoV-2 infection.The public antibody clonotypes were shared by distinct convalescent individuals.Moreover,several antibodies isolated by LIBRA-seq showed high binding affinity against SARS-CoV-2 receptor-binding domain(RBD)or nucleoprotein(NP)via ELISA assay.Two RBD-reactive antibodies C14646P3S and C2767P3S isolated by LIBRA-seq exhibited high neutralizing activities against both pseudotyped and authentic SARS-CoV-2 viruses in vitro.Our study provides fundamental insights into B cell response following SARS-CoV-2 infection at the single-cell level. | Bing He Shuning Liu Yuanyuan Wang Mengxin Xu Wei Cai Jia Liu Wendi Bai Shupei Ye Yong Ma Hengrui Hu Huicui Meng Tao Sun Yanling Li Huanle Luo Mang Shi Xiangjun Du Wenjing Zhao Shoudeng Chen Jingyi Yang Haipeng Zhu Yusheng Jie Yuedong Yang Deyin Guo Qiao Wang Yuwen Liu Huimin Yan Manli Wang Yao-Qing Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 2 |
| 4 | Steered molecular dynamics simulations on the binding of the appendant structure and helix-b2 in domain - swapped human cystatin C dimer 显示文摘 | Shen Manli Guan Jing Xu Linan Yu Yuan He Jianwei Jones Gary W and Song Youtao | 2012 | Journal of Biomolecular Structure and Dynamics2012，30，6： | 1 |
| 5 | Characterization of GMZbentonite and its application in the adsorption of Pb(II)from aqueoussolutions显示文摘 | Wang Suowei Dong Yunhui He Manli | 2009 | Appl Clay Sci2009，43，2： | 1 |
| 6 | Analysis of parental genetic diversity and its impact on grain yield and quality of japonica hybrid rice in northern China显示文摘The relationship between parental genetic differences and the quality and yield of japonica hybrid rice strongly influences japonica hybrid rice breeding.In this study,137 parental lines of japonica hybrid rice were genotyped using 8 K rice SNP-Chips to characterize their genetic diversity,population structure,and indica-genotype proportion.The genetic diversity of total parental lines averaged 0.264,with values of0.287 for restorer lines and 0.148 for the sterile lines.The introduction of indica lineage increased the genetic diversity of restorer lines relative to that of sterile lines.By model-based population structure analysis,the 137 lines were divided into 14 groups.According to the grouping results,eight restorer lines and five sterile lines were selected from different groups for cross breeding,yielding 40 japonica hybrid rice combinations(F1).Investigation of the yield and quality of these combinations showed that highyield combinations could be obtained by increasing parental genetic distance to 0.8–0.9,a result accomplished largely by the introduction of indica genomic components of restorer lines.To further improve grain quality,the genetic distance between parents should be reduced to 0.4–0.5,suggesting an indicagenotype proportion of 30%–40%for restorer lines.This study may provide a reference for breeding of japonica hybrid rice. | Hong Gao Zuobin Ma Yuanzheng Wang Manli Zhang Xianju Wang Changhua Wang Zhiqiang Tang Liying Zhang Liang Fu Na He Hui Wang Yongan Yin Yuanjun Bai Guomin Sui Wenjing Zheng | 2022 | The Crop Journal2022，10，3： | 1 |
| 7 | Functional Characterization of the Group Ⅰ Alphabaculovirus Specific Gene ac73显示文摘Baculoviridae is a family of large DNA viruses that specifically infect insects.It contains four genera,Alpha-,Beta-,Gamma-,and Deltabaculovirus.Alphabaculovirus is further divided into Group I and II,and Group I appears to be emerged most recently among all baculoviruses.Interestingly,there are 12 Group I specific genes that are only found in this lineage.Studying these genes is helpful to understand how baculoviruses evolved.Here,we reported the functional analyzing results of ac73y a function unknown Group I specific gene of Autographa califomica multiple nucleopolyhedrovirus(AcMNPV)which is the type species of baculovirus.The AC73 protein encoded by ac73 was found to be expressed during the late stage of infection and incorporated into the nucleocapsids of budded virus(BV)and occlusionderived virus(ODV).In infected cells,AC73 resided mainly in the ring zone region of the nucleus,and appeared to be assembled into occlusion bodies(OBs).The ac73 knockout and repaired viruses were constructed and studied by in vitro and in vivo infection.Although ac73 was not essential for BV and ODV or OB formation,the BV titer and viral infectivity in insect larvae of ac73 knockout AcMNPV decreased by about 5-8 and 3-4 fold compared to those of wild type virus,respectively,suggesting ac73 contributed to infectious BV production and viral infectivity in vivo.This research provides new insight into the function of this Group I specific gene. | Wei Shao Lihong He Qingxiu Chen Jiang Li Fei Deng Hualin Wang Zhihong Hu Manli Wang | 2019 | Virologica Sinica2019，34，6： | 0 |
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