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| 1 | Notch signaling:Its essential roles in bone and craniofacial development显示文摘Notch is a cellecell signaling pathway that is involved in a host of activities including development,oncogenesis,skeletal homeostasis,and much more.More specifically,recent research has demonstrated the importance of Notch signaling in osteogenic differentiation,bone healing,and in the development of the skeleton.The craniofacial skeleton is complex and understanding its development has remained an important focus in biology.In this review we briefly summarize what recent research has revealed about Notch signaling and the current understanding of how the skeleton,skull,and face develop.We then discuss the crucial role that Notch plays in both craniofacial development and the skeletal system,and what importance it may play in the future. | Mikhail Pakvasa Pranav Haravu Michael Boachie-Mensah Alonzo Jones Elam Coalson Junyi Liao Zongyue Zeng Di Wu Kevin Qin Xiaoxing Wu Huaxiu Luo Jing Zhang Meng Zhang Fang He Yukun Mao Yongtao Zhang Changchun Niu Meng Wu Xia Zhao Hao Wang Linjuan Huang Deyao Shi Qing Liu Na Ni Kai Fu Michael J.Lee Jennifer Moriatis Wolf Aravind Athiviraham Sherwin S.Ho Tong-Chuan He Kelly Hynes Jason Strelzow Mostafa El Dafrawy Russell R.Reid | 2021 | Genes & Diseases2021，8，1： | 4 |
| 2 | Benzimidazolium Functionalized Polysulfone-based Anion Exchange Membranes with Improved Alkaline Stability显示文摘The stability of anion exchange membranes(AEMs) is an important feature of alkaline exchange membrane fuel cells(AEMFCs), which has been extensively studied. However it remains a real challenge due to the harsh working condition. Herein, we developed a novel type of polysulfone-based AEMs with three modified 1,2-dimethylbenzimidazoliums containing different substitutes at C4-and C7-position. The results showed that the introduction of the substitutes could obviously improve the dimensional and alkaline stabilities of the corresponding membranes. The swelling ratios of resultant AEMs were all lower than 10% after water immersion. The membrane with 4,7-dimethoxy-1,2-dimethylbenzimidazolium group exhibited the highest alkaline stability. Only 9.2% loss of hydroxide conductivity was observed after treating the membrane in 1 mol·L^(-1) KOH solution at 80 °C for 336 h. Furthermore, the density functional theory(DFT) study on the three functional group models showed that the substitutes at C4-and C7-position affected the lowest unoccupied molecular orbital(LUMO) energies of the different 1,2-dimethylbenzimidazolium groups. | Yu Pan Ting-Yun Wang Xiao-Ming Yan Xiao-Wei Xu Qi-Dong Zhang Bao-Lin Zhao Issam El Hamouti Ce Hao Gao-Hong He | 2018 | Chinese Journal of Polymer Science2018，36，1： | 2 |
| 3 | Differential activation of extracellular signal-regulated protein kinase 1/2 and p38 mitogen activated-protein kinase by AT1 receptors in vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats显示文摘 | Touyz RM He G El Mabrouk M | 2001 | J Hypertens2001，19，32： | 1 |
| 4 | Functional and structural con- neelivity between the perigenual anterior cingulate and amygda- la in bipolar disorder显示文摘 | Wang F Kalmar JH He Y el al | 2009 | Biol Psychiatry2009，66，5： | 1 |
| 5 | Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells 显示文摘 | Davenport EL Moore HE Dunlop AS | 2007 | Blood2007，110，7： | 1 |
| 6 | Thermokeratoplasty显示文摘 | Gasset AR Schaw EL Kaufman HE | 1973 | Trans Am Acard Ophthamal Otolaryngol1973，77，4： | 1 |
| 7 | Human endothelial progenitor cells tolerate oxidative stress due to intrinsical y high expression of manganese superoxide dismutase显示文摘 | He T Peterson TE Holmuhamedov EL | | 0，，11： | 1 |
| 8 | Tumor necrosis factor α blockade restores growth hormone signaling in murine colitis显示文摘 | Difedele LM He J Bonkowski EL | | 0，，05： | 1 |
| 9 | Themml characterization of an epoxy- I)ast underfill material for flip chip packaging 显示文摘 | He Y Moreira B E Overson A el al | 2000 | llmnnochinfiea Aeta2000，3573，14： | 1 |
| 10 | Estimating land use im- pacts on regional scale urban water balance and groundwa- ter recharge显示文摘 | He B Wang Y Takase K el al | 2009 | Water Resources Manage2009，，23： | 1 |
| 11 | Adiponectin gene polymorphisms in Egyptian type 2 diabetes mellitus patients with and without diabetic nephropathy显示文摘 | El Shal AS Zidan HE Rashad NM | 2014 | Mol Bid Rep2014，41，4： | 1 |
| 12 | Nuclear magnetic resonance conformational studies of the chemotactic tripeptide formyl-L-methionyl-L-leucyl-L-phenylalanine: a small 13 sheet 显示文摘 | Becker EL Bleich HE Day AR | 1979 | Biochemistry1979，18，21： | 1 |
| 13 | Effect of Mg and Si in the aluminum on the thermo-mechani- cal properties of presst, relcss infihrated SiCp/A1 com- posites显示文摘 | REN Hu-bin HE Xin-bo QU Xuan-hui el ell | 2007 | Composites Science arid Technology2007，67，10： | 1 |
| 14 | Role of lymphangiogenic factors in tumor metastasis显示文摘 | He Y Karpanen T Alitalo el al | 2004 | Biochimica Biophysica Acta2004，1654，1： | 1 |
| 15 | Clinical value of serum uric acid in patients with suspected coronary artery disease显示文摘 | Lira HE Kim SH Kim El | 2010 | Korean J Intern Med2010，25，1： | 1 |
| 16 | Asymptomatic periPheral arterial oculusive disease predicted cardiovascular morbidit y and mortality in a 7-year follow-up study显示文摘 | Hooi JD Kester AD Stoffers HE el al | 2004 | J Clin Epidemiol2004，57，： | 1 |
| 17 | Molecular Mimicry Regulates ABA Signaling by SnRK2 Kinases and PP2C Phosphatases显示文摘 | Soon F F Ng L M Zhou X E West G M Kovach A Tan M H Suino-Powell KM He Y Xu Y Chalmers MJ Brunzelle JS Zhang H Yang H Jiang H Li J Yong EL Cutler S Zhu JK Griffin PR Melcher K Xu HE | 2012 | Science2012，335，6064： | 1 |
| 18 | Filamin A-mediated Down-regu lation of the Exchange FactorRas-GRF1 Correlates with Decreased Matrix Metalloproteinase-9 Expression in Human Melanoma Cells显示文摘 | Zhu TN He H J Kole S el al | 2007 | J Biol Chem2007，282，14： | 1 |
| 19 | Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells 显示文摘 | Davenport EL Moore HE Dunlop AS | 2007 | Blood2007，110，7： | 1 |
| 20 | Experimental research on the electromagnetic emission of rock and coal burst failure显示文摘 | Dou Linming He Xueqiu Wang Engyuan et el | 2000 | Zeszyty Naukowe Politechniki Slaskiej2000，，246： | 1 |
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