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| 1 | EGF基因多态性与结直肠癌的关系显示文摘 | 吴国洋 Michael Keese Till Hasenberg Jrg W.Sturm | 2005 | 中华普通外科杂志2005，20，11： | 9 |
| 2 | 结直肠癌术后吻合口瘘与表皮生长因子、转化生长因子-β1、血管内皮生长因子基因多态性的关系显示文摘目的观察表皮生长因子(EGF)61*G/A、转化生长因子-β1(TGF-β1)-509*TIC、血管内皮生长因子(VEGF)936*T/C基因功能多态性对术后结肠吻合口瘘的影响。方法采用聚合酶链反应-限制性片段长度多态性(PCR—RFLP)方法检测伴有和不伴有术后结肠吻合口瘘结直肠癌患者的EGF 61*G/A,TGF-β1—509*T/C,VEGF 936*T/C基因型。结果伴有术后结肠吻合口瘘的结直肠癌患者TGF-β1-509*T/T基因型比例(0.0%)低于无术后吻合口瘘的患者(15.2%),两者差异有统计学意义(P〈0.05)。伴有术后结肠吻合口瘘的VEGF 936*C/C基因型和C等位基因比例(65.9%和80.6%)低于无术后吻合口瘘的患者(82.6%和90.5%),两者差异有统计学意义(基因型x^2=5.755,P〈0.05;等位基因x^2=5.275,P〈0.05)。伴有术后结肠吻合口瘘的结直肠癌患者EGF 61*G/G基因型比例(25.0%)低于无术后吻合口瘘的患者(55.5%),但两者差异无统计学意义(x^2=1.591,P〉0.05)。结论TGF-β1-509*T/T基因型,VEGF 936*C/C基因型或936*C等位基因有助于减少术后结肠吻合口瘘的发生。 | 吴国洋 王效民 Michael Keese Till Hasenberg Jǒrg W. Sturm | 2008 | 中华实验外科杂志2008，25，3： | 5 |
| 3 | 血管内皮生长因子936T/C基因多态性与结直肠癌及术后吻合口瘘的关系显示文摘目的通过研究血管内皮生长因子(VEGF)936T/C基因多态性了解该因子对结直肠癌生成及术后结肠吻合口瘘的影响。方法采用聚合酶链反应-限制性片段长度多态性(PCR-RFLP)方法检测结直肠癌及正常对照的VEGF936T/C基因型。结果结直肠癌患者VEGF936T/C基因型或等位基因与对照组相比无差异。伴有术后结肠吻合口瘘的结直肠癌患者其VEGF936C/C基因型及C等位基因比例低于无术后结肠吻合口瘘的患者,两者差异有统计学意义(P<0·05)。结论VEGF936C/C基因型或936C等位基因与结直肠癌的发生无关,但提示术后结肠吻合口瘘的发生率降低。 | 吴国洋 王效民 Michael Keese Till Hasenberg Jrg W. Sturm | 2006 | 中华外科杂志2006，44，21： | 4 |
| 4 | TGF-β1-509 T/T基因型与结直肠癌患者术后结肠吻合口瘘的关系显示文摘目的通过研究转化生长因子-β1(TGF-β1)基因功能的多态性,了解TGF-β1因子对结直肠癌术后结肠吻合口瘘的影响。方法采用PCR-RFLP方法检测结直肠癌组内157例伴有或不伴有术后结肠吻合口瘘患者及对照组117例的TGF-β1-509 T/C基因型。结果伴有术后结肠吻合口瘘的患者TGF-β1-509 T/T。基因型比例(0)低于无吻合口瘘的患者(13.2%),两者差异有统计学意义(P=0.012)。结直肠癌组TGF-β1-509基因型或等位基因与对照组差异无统计学意义(基因型χ^2=0.981,P〉0.05;等位基因χ^2=0.000,P〉0.05)。结论具TGF-β1-509 T/T基因型者术后结肠吻合口瘘的发生率较低。而TGF-β1-509 T/C基因多态性与结直肠癌的发生及发展无关。 | 吴国洋 王效民 Michael Keese Till Hasenberg Jorg W. Sturm | 2007 | 中华普通外科杂志2007，22，5： | 2 |
| 5 | A survey of perioperative therapy for elective colon resection in Germany, 2006显示文摘 | Hasenberg T Rittler P Post S | 2007 | Der Chirurg2007，78，9： | 1 |
| 6 | Perioperanve quality of care is modulated by process management with clinical pathways for fast-tracksurgery of the colon 显示文摘 | Sehwarzbaeh M Hasenberg T Linkc M | 2011 | Int J Colorectal Dis2011，26，12： | 1 |
| 7 | Intestinal barrier dysfunction in developing liver cirrhosis:an in vivo analysis of bacterial translocation显示文摘 | Palma P Mihaljevic N Hasenberg T | 2007 | Hepatol Res2007，37，1： | 1 |
| 8 | Mast cell and maerophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation 显示文摘 | De Filippo K Dudeck A Hasenberg M | 2013 | Blood2013，121，24： | 1 |
| 9 | ‘Fast-track’ colonic surgery in Austria and Germany-results from the survey on patterns in current perioperative practice显示文摘 | Hasenberg T Keese M Lngle F | 2009 | Colorectal Dis2009，11，2： | 1 |
| 10 | Association between EGF, TGF-betal, VEGF gene polymorphism and colorectal cancer 显示文摘 | Wu GY Hasenberg T Magdeburg R | 2009 | World Journal Surgery2009，33，1： | 1 |
| 11 | 'Fast-track' colonic surgery in Austria and Germany-results from the survey on patterns in current perioperative practice显示文摘 | Hasenberg T Keese M L(a)ngle F | 2009 | Colorectal Dis2009，11，2： | 1 |
| 12 | Early supplementation of parenteral nutrition is capable of improving quality of life,chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment Results from a prospective,randomized clinical trial显示文摘 | Hasenberg T Essenbreis M Herold A | 2010 | Colorectal Dis2010，12，： | 1 |
| 13 | 'Fast-track' colonic surgery in Austria and Germany-results from the survey on patterns in current perioperative practice 显示文摘 | Hasenberg T Keese M Langle F etal | 2009 | Colorectal Dis2009，11，2： | 1 |
| 14 | Cancer patients and characteristics of pulmonary embolism显示文摘 | Hasenberg U Paul T Feuersenger A | 2009 | Eur J Radiol2009，69，3： | 1 |
| 15 | Current perioperative practice in rectal surgery in Austria and Germany 显示文摘 | Hasenberg T L:ingle F Reibenwein B | 2010 | Int J Color- ectal Dis2010，25，7： | 1 |
| 16 | Persistent im- mune activation in HIV-1 infection is associated with progression to AIDS显示文摘 | Hasenberg MD Otto SA van Benthem BH | 2003 | AIDS2003，17，13： | 1 |
| 17 | 'Fast-track' colonic surgery in Austria and Germany-results from the survey on patterns in current perioperative practice显示文摘 | Hasenberg T Keese M L(a)ngle F | 2009 | Colorectal Dis2009，11，2： | 1 |
| 18 | “Fast-track” colonic surgery in austria and germany-result from the survey on patterns in current perioperative practice 显示文摘 | Hasenberg T Keese M angle L | 2009 | Colorectal Dis2009，11，2： | 1 |
| 19 | Mast cell and macrophage chemokines CXCL1/CXCI2 control the early stage of ncutrot,hi recruitment during tissue inflammation显示文摘 | De Hhppo K Dudeck A Hasenberg M | 2013 | Blood2013，121，24： | 1 |
| 20 | Perioperative quality of care is modulated by process management with clinical pathways for fast-track surgery of the colon显示文摘 | Schwarzbach M Hasenberg T Linke M | 2011 | Int J Colorectal Dis2011，26，： | 1 |
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