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| 1 | Gallbladder function and dynamics of bile flow in asymptomatic gallstone disease显示文摘AIM:To investigate the effects of gallbladder stones on motor functions of the gallbladder and the dynamics of bile flow in asymptomatic gallstone disease.METHODS:Quantitative hepatobiliary scintigraphy was performed to detect the parameters of gallbladder motor function [gallbladder ejection fraction(GBEF),gallbladder visualization time(GBVT),gallbladder time to peak activity(GBTmax),gallbladder half emptying time(GBT1/2),and transit time of bile to duodenum(TTBD)] in 24 patients with asymptomatic cholelithiasis who were diagnosed incidentally during routine abdominal ultrasonographic examination and 20 healthy subjects with normal gallbladder.RESULTS:Even though there was no significant difference in the clinical and laboratory parameters between the patient and control groups,all parameters of gallbladder function except TTBD were found to differ significantly between the two groups.GBEF in the patient group was decreased(P=0.000) and GBVT,GBTmax,GBT1/2 in the patient group were longer(P=0.000,P=0.015,P=0.001,respectively).CONCLUSION:Our results showed that even if there were not any clinical and laboratory findings,gallbladder filling and emptying could be impaired in patients with gallstone disease. | Sevim Süreyya eri Feride Meltem zbek Celal eri Bahattin Baykal Hasan Erol Eroglu Zeynep Baykal Mustafa Yildiz Semahat Saglam Ahmet Yesildag | 2009 | World Journal of Gastroenterology2009，15，22： | 8 |
| 2 | Gut microbiota profile in healthy Indonesians显示文摘BACKGROUND Recently, gut microbiota has been associated with various diseases other than intestinal disease. Thus, there has been rapid growth in the study of gut microbiota. Considering the numerous factors influencing gut microbiota such as age, diet, etc., area-based research is required. Indonesia has numerous different tribes and each of these tribes have different lifestyles. Hence, it is expected that each tribe has a specific gut microbiota. A deeper insight into the composition of gut microbiota can be used to determine the condition of gut microbiota in Indonesians and to consider which treatment may be suitable and effective to improve health status.AIM To investigate the gut microbiota of Indonesian subjects represented by Javanese and Balinese tribes by analyzing fecal samples.METHODS Fecal samples were collected from a total of 80 individuals with 20 in each of the young groups ranging from 25-45 years and the elderly group aged 70 years or more from two different regions, Yogyakarta and Bali. Fecal sample collection was performed at the end of the assessment period(day 14 ± 1 d) during which time the subjects were not allowed to consume probiotic or antibiotic products.The quantification of various Clostridium subgroups, Lactobacillus subgroups,Enterococcus, Streptococcus, Staphylococcus, Bacteroides fragilis group and Prevotella,Bifidobacterium and Atopobium cluster, Enterobacteriaceae and Pseudomonas was performed using the Yakult intestinal flora-scan(YIF-SCAN).RESULTS The bacterial population in younger subjects' feces was higher than that in the elderly population, with a total of approximately 10.0 – 10.6 log10 bacterial cells/g feces. The most abundant bacteria in all groups were Clostridium, followed by Prevotella, Atopobium, Bifidobacterium and Bacteroides. In the elderly, an increase in Enterobacteriaceae, Coliform and Escherichia coli was found. In terms of bacterial counts in Yogyakarta, total bacteria, Clostridium coccoides(C. coccoides) group,Bifidobacterium, Prevotella, Lactobacillus plantarum subgroup, and Streptococcus were significantly higher(P < 0.05) in younger than elderly subjects, while the Lactobacillus gasseri subgroup, Lactobacillus casei subgroup, and Lactobacillus reuteri subgroup counts were significantly lower(P < 0.05) in younger subjects. In Balinese subjects, total bacteria, C. coccoides group, Clostridium leptum subgroup,Bacteroides fragilis group, and Prevotella were significantly higher(P < 0.05) in younger compared to elderly individuals, while the Lactobacillus ruminis subgroup, and Enterobacteriaceae were significantly lower(P < 0.05) in younger subjects. The results also revealed that, besides the C. coccoides group and Clostridium leptum group being the most abundant gut microbiota in both Yogyakarta and Balinese people, the latter was indicated by a higher Clostridium perfringens count, which was almost 10 times that of Yogyakarta subjects. This may be a response to different lifestyles in the different tribes; however, this phenomenon requires further extensive study.CONCLUSION Bacterial populations were higher in younger than in elderly subjects. Most abundant bacterial groups were Clostridium, Prevotella, Atopobium, Bifidobacterium,and Bacteroides. The level of Clostridium perfringens in Yogyakarta subjects was lower than that in Balinese subjects. | Endang Sutriswati Rahayu Tyas Utami Mariyatun Mariyatun Pratama Nur Hasan Rafli Zulfa Kamil Ryan Haryo Setyawan Fathyah Hanum Pamungkaningtyas IskANDar Azmy Harahap Devin Varian Wiryohanjoyo Putrika Citta Pramesi Muhammad Nur Cahyanto I Nengah Sujaya Mohammad Juffrie | 2019 | World Journal of Gastroenterology2019，25，12： | 6 |
| 3 | Carvedilol vs endoscopic variceal ligation for primary and secondary prevention of variceal bleeding: Systematic review and metaanalysis显示文摘BACKGROUND Variceal hemorrhage is associated with high mortality and is the cause of death for 20–30%of patients with cirrhosis.Nonselectiveβblockers(NSBBs)or endoscopic variceal ligation(EVL)are recommended for primary prevention of variceal bleeding in patients with medium to large esophageal varices.Meanwhile,combination of EVL and NSBBs is the recommended approach for the secondary prevention.Carvedilol has greater efficacy than other NSBBs as it decreases intrahepatic resistance.We hypothesized that there was no difference between carvedilol and EVL intervention for primary and secondary prevention of variceal bleeding in cirrhosis patients.AIM To evaluate the efficacy of carvedilol compared to EVL for primary and secondary prevention of variceal bleeding in cirrhotic patients METHODS We searched relevant literatures in major journal databases(CENTRAL,MEDLINE,and EMBASE)from March to August 2018.Patients with cirrhosis and portal hypertension,regardless of aetiology and severity,with or without a history of variceal bleeding,and aged≥18 years old were included in this review.Only randomized controlled trials(RCTs)that compared the efficacy of carvedilol and that of EVL for primary and secondary prevention of variceal bleeding and mortality in patients with cirrhosis and portal hypertension were considered,irrespective of publication status,year of publication,and language.RESULTS Seven RCTs were included.In four trials assessing the primary prevention,no significant difference was found on the events of variceal bleeding(RR:0.74,95%CI:0.37-1.49),all-cause mortality(RR:1.10,95%CI:0.76-1.58),and bleedingrelated mortality(RR:1.02,95%CI:0.34-3.10)in patients who were treated with carvedilol compared to EVL.In three trials assessing secondary prevention,there was no difference between two interventions for the incidence of rebleeding(RR:1.10,95%CI:0.75-1.61).The fixed-effect model showed that,compared to EVL,carvedilol decreased all-cause mortality by 49%(RR:0.51,95%CI:0.33-0.79),with little or no evidence of heterogeneity.CONCLUSION Carvedilol had similar efficacy to EVL in preventing the first variceal bleeding in cirrhosis patients with esophageal varices.It was superior to EVL alone for secondary prevention of variceal bleeding in regard to all-cause mortality reduction. | Michael Dwinata David Dwi Putera Muhamad Fajri Adda’i Putra Nur Hidayat Irsan Hasan | 2019 | World Journal of Hepatology2019，11，5： | 6 |
| 4 | Can firms learn by observing? Evidence from cross-border M&As 显示文摘 | Francis B B Hasan I Sun X Waisman M | 2014 | Journal of Corporate Finance2014，25，： | 1 |
| 5 | Investigation of local- ized dryout versus CHF in saturated flow boiling显示文摘 | Konishi C Mudawar I Hasan M M | 2013 | Inter- national Journal of Heat and Mass Transfer2013，67，： | 1 |
| 6 | European Banking Performance Beyond Country Borders: What Really Matters? 显示文摘 | Lozano-Vivas A Pastor J T Hasan I | 2001 | The European Financial Review2001，5，： | 1 |
| 7 | “Privatization matters: Bank efficiency in transition countries”显示文摘 | Bonin J P Hasan I Wachtel P | 2005 | Journal of Banking & Finance2005，，29： | 1 |
| 8 | A fault syndromes simulator for random access memories显示文摘 | Hasan W Z W Halin I A Sidek R | 2008 | European Journal of Scientific Research2008，23，1： | 1 |
| 9 | “Ownership, Governance, and Bank Performance: Korean Experience”显示文摘 | Choi S Hasan I | 2005 | Financial Markets Institutions & Instruments2005，，： | 1 |
| 10 | Institutional Development, Financial Deepening and Economic Growth:Evidence from China 显示文摘 | HASAN I WACHTEL P ZHOU M | 2009 | Journal of Banking & Finance2009，33，： | 1 |
| 11 | Political connections and the process of going public:evidence from China显示文摘 | FRANCIS B B HASAN I SUN X | 2009 | Journal of International Money and Finance2009，，28： | 1 |
| 12 | Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention 显示文摘 | Williams JL Borgo S Hasan I | 2001 | Cancer Res2001，61，8： | 1 |
| 13 | Minimizing boil-off losses in liquefied natural gas transportation显示文摘 | Faruque Hasan M M Alfred Minghan Zheng Karimi I A | 2009 | Industrial & Engineering Chemistry Research2009，48，： | 1 |
| 14 | Further Evidence on the Link Between Finance and Growth: An International Analysis of Community Banking and Economic Performance 显示文摘 | Berger A N Hasan I Klapper L | 2004 | Journal of fi- nancial Services Research2004，，25： | 1 |
| 15 | Further Evidence on the Link Between Finance and Growth: An International Analysis of Community Banking and Economic Performance 显示文摘 | BERGER A N HASAN I KLAPPER L F | 2004 | Journal of Financial Services Research2004，25，： | 1 |
| 16 | Bank Ownership and Efficiency in China : What will Happen in the World's Largest Nation? 显示文摘 | Berger N A Hasan I Zhou M M | 2009 | Journal of Banking & Finance2009，，33： | 1 |
| 17 | Problems leading to conversion in laparoscopic cholecystectomy 显示文摘 | Ahmed S A|i AA Hasan M Awal A | 2013 | Mymensingh Med J2013，22，1： | 1 |
| 18 | Diverse sequence types of Klebsiella pneumoniae contribute to the dissenfination of blaNll in In- dia, Sweden, and the United Kingdom显示文摘 | Giske CG Froding I Hasan CM | 2012 | Antimicrob Agents Che- mother2012，56，5： | 1 |
| 19 | Elevated serum CCL2 concomitant with a reduced mycobacterium-induced response leads to disease dissemination in leprosy显示文摘 | Hasan Z Jamil B Zaidi I | | 0，，03： | 1 |
| 20 | Coupled Turbulent Flow, Heat, and Solute Transport in Continuous Casting Process显示文摘 | Aboutalebi M R Hasan M Guthrie R I L | 1995 | Metall Mater Trans1995，26，4： | 1 |
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