|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | IVlelatonin ameliorates the adverse effects of leptin on sperm显示文摘 | Fayez A Almabhouh Khairul Osman Siti Fatimah Ibrahim Sergey Gupalo Justin Gnanou Effendi Ibrahim Harbindar Jeet Singh | 2017 | Asian Journal of Andrology2017，19，6： | 2 |
| 2 | Leptin and its actions on reproduction in males显示文摘Leptin, an adipocyte-derived hormone, serves numerous physiological functions in the body, particularly during puberty and reproduction. The exact mechanism by which leptin activates the gonadotropin-releasing hormone (GnRH) neurons to trigger puberty and reproduction remains unclear. Given the widespread distribution of leptin receptors in the body, both central and peripheral mechanisms involving the hypothalamic-pituitary-gonadal axis have been hypothesized. Leptin is necessary for normal reproductive function, but when present in excess, it can have detrimental effects on the male reproductive system. Human and animal studies point to leptin as a link between infertility and obesity, a suggestion that is corroborated by findings of low sperm count, increased sperm abnormalities, oxidative stress, and increased leptin levels in obese men. In addition, daily leptin administration to normal-weight rats has been shown to result in similar abnormalities in sperm parameters. The major pathways causing these abnormalities remain unidentified;however, these adverse effects have been attributed to leptin-induced increased oxidative stress because they are prevented by concurrently administering melatonin. Studies on leptin and its impact on sperm function are highly relevant in understanding and managing male infertility, particularly in overweight and obese men. | Ifrah Alam Malik Damayanthi Durairajanayagam Harbindar Jeet Singh | 2019 | Asian Journal of Andrology2019，21，3： | 2 |
| 3 | Tissue kallikrein and kininogen levels in fetoplacental tissues from normotensive pregnant women and women with pregnancy-induced hypertension显示文摘 | Mahaneem Mohamed Ernest T. Larmie Harbindar J. Singh Mohd. S. Othman | 2006 | European Journal of Obstetrics and Gynecology2006，，1： | 1 |
| 4 | 褪黑素对大鼠妊娠结局的影响(英文)显示文摘褪黑素能调节多项生理功能,但其对妊娠结局的影响所知甚少。本研究旨在探讨补充褪黑素对12~1aN龄的Wistar-Kyoto(WKY)和Sprague-Dawley(SD)大鼠妊娠结局的影响。动情前期确认后,每只雌性大鼠与一只同品种雄性大鼠同笼饲养过夜,第二天阴道涂片确认交配后,雌性大鼠转移至单独的代谢笼,WKY大鼠每天给予含0、25、50或100mg/kg褪黑素的饮水,SD大鼠则每天给予含0或100mg/kg褪黑素的饮水,从怀孕第一天持续至产后21天。记录母鼠体重、孕期、窝产仔数、仔鼠出生体重和出生后7~42d体重及仔鼠死亡率,使用重复测量的方差分析对数据进行分析。结果显示,与对照组相比,褪黑素组母鼠孕期体重增长较小(P〈0.01),窝产仔数减少(尸〈0.01),仔鼠平均出生体重仅在100mg/kg褪黑素组显著降低(P〈0.001),出生后7~42d仔鼠平均体重显著降低(P〈0.01)。25和100mg/kg褪黑素组WKY仔鼠死亡率分别为9.5%和21.6%,且都发生在断奶21天后。以上结果提示,产前和产后补充褪黑素会严重影响WKY和SD大鼠窝产仔数、仔鼠生长和死亡率。 | Harbindar Jeet Singh Hisham Ibrahim Saleh Sergey Gupalo Effat Omar | 2013 | 生理学报2013，65，2： | 1 |
| 5 | Tissue Kallikrein and kininogen levels in fetoplacental tissues from normotensive pregnant women and women with pregnancyin-duced hypertension显示文摘 | Mahaneem M Ernest TL Harbindar JS | 2007 | European Journal of Obstetrics & Gynecology and Reproductive Biology2007，134，1： | 1 |
| 6 | Tissue kal-likrein and kininogen levels in fetoplacental tissues from normo-tensive pregnant women and women with pregnancy-induced hypertension显示文摘 | Mahaneem M Ernest TL Harbindar JS | 2007 | European Journal of Obstetrics & Gynecolo-gy and Reproductive Biology2007，134，： | 1 |
| 7 | Tissue Kallikrein and kininogen levels in fetoplacental tissues from normotensive pregnant women and women with pregnancyinduced hypertension显示文摘 | Mahaneem M Emest TL Harbindar JS | | 0，，01： | 1 |
| 8 | Tissue kallikrein and kininogen levels in fetoplacental tissues from normotensive pregnant women and women with pregnancy-induced hypertension显示文摘 | Mahaneem M Ernest T L Harbindar J S | | 0，，01： | 1 |
| 9 | Tissue kallikrein and kininogen levels in fetoplacental tissues from normotensive pregnant women and women with pregnancyinduced hypertension显示文摘 | Mahaneem M Ernest TL Harbindar JS | 2007 | European Journal of Obstetrics & Gynecology and Reproductive Biology2007，134，1： | 1 |
| 10 | Tissue kallikrein and kininogen levels in fetoplaeental tissues from normotensive pregnant women and women with pregnancy-in duced hypertension显示文摘 | Mahaneem M Ernest TL Harbindar JS | 2007 | European Journal of Obstetrics &Gynecology and Reproductive Biology2007，134，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员