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| 1 | IL-10high producing genotype predisposes HIV infected individuals to TB infection显示文摘 | Ramaseri Sunder S Hanumanth SR Nagaraju RT | 2012 | Hum Immunol2012，73，6： | 1 |
| 2 | A clinical and biochemical study of chronic fluoride toxicity in children of kheruthanda of gulbarga district,Karnataka,India显示文摘 | Shivashankara AR Shivaraja SYM Hanumanth RS | 2000 | Fluoride2000，，33： | 1 |
| 3 | Antihepatotoxic Effect of Punica granatum . Acetone Extract Against Isoniazid- and Rifampicin-Induced Hepatotoxicity显示文摘 | Surinderkumar Yogeeta Hanumanth Rao Balaji Ragavender Thiruvengadam Devaki | 2007 | Pharmaceutical Biology2007，，： | 1 |
| 4 | 基于筛选安全的共低积累基因型评价空心菜对镉和硝酸盐积累的变异(英文)显示文摘目的:筛选镉-硝酸盐共低积累空心菜基因型,并研究降低空心菜重金属含量,提高营养品质的农艺措施。创新点:首次筛选得到镉-硝酸盐共低积累空心菜基因型,并研究空心菜可食部污染物、矿质元素和营养指标之间的相关性,提出进一步降低空心菜可食部镉和硝酸盐含量的农艺措施。方法:共38个空心菜基因型收集于世界各地,种植在连作了7年的中度镉-硝酸盐复合污染土壤上(Cd1.10 mg/kg,NO_3^-235.2 mg/kg),4周后收获。用HNO_3-HClO_4(体积比5:1)消煮,电感耦合等离子体质谱仪(ICP-MS)测定各种金属元素,水杨酸-硫酸比色法测定硝酸盐含量,钒钼黄比色法测定磷含量,2,6-二氯靛酚滴定法测定维生素C含量,乙醇-丙酮(体积比2:1)比色法测定叶绿素含量。结论:本试验筛选得到镉-硝酸盐共低积累空心菜基因型4个(Cd<0.71 mg/kg DW,NO_3^-<3100 mg/kgFW),分别是JXDY、GZQL、XGDB和B888,可以在中轻度镉-硝酸盐复合污染土壤上安全生产。空心菜地上部镉与铅、锌含量呈正相关,而这3种元素均与磷量呈负相关。这些结果表明镉、铅和锌通过相同的途径被空心菜吸收,可以同时被治理。增加磷肥供应率可以抑制复合污染土壤中的镉和硝酸盐向空心菜可食部的转移。 | Lin TANG Wei-jun LUO Zhen-li HE Hanumanth Kumar GURAJALA Yasir HAMID Kiran Yasmin KHAN Xiao-e YANG | 2018 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2018，19，2： | 1 |
| 5 | Association of TAP 1 and 2 gene polymorphisms with human immunodeficiency virus- tuberculosis co-infection 显示文摘 | Sunder SR Hanumanth SR Gaddam S | 2011 | Hum Immunol2011，72，10： | 1 |
| 6 | Particle incorporation by melt stirring for the production of metal matrix composites显示文摘 | Hanumanth G S | 1993 | J Mater Sci1993，28，9： | 1 |
| 7 | Irons显示文摘 | HANUMANTH G | 1993 | Journal of Materials Science1993，28，： | 1 |
| 8 | Wing morphology and flight development in the short- nosed fruit bat Cynopterus sphinx 显示文摘 | VADAMALAI E ELANGOVAN Y S P HANUMANTH R | 2007 | Zoology2007，110，： | 1 |
| 9 | Association of TAP1 and 2 gene polymorphisms with human immunodeficiency virus-tuberculosis co-infection显示文摘 | Sunder S R Hanumanth S R Gaddam S | 2011 | Human immunology2011，72，10： | 1 |
| 10 | A clinical and biochemical study of chronic fluoride toxicity in children of kheru thanda of gulbarga district, Karnataka, India显示文摘 | Shivashankara AR Shivaraja SYM Hanumanth RS | 2000 | Fluoride2000，33，： | 1 |
| 11 | A chinical and biochemical study of chronic fluoride toxicity in children of kheruthanda of gulbarga district,Kamataka,India显示文摘 | SHIVASHANKARA A R SHIVARAJA S Y M HANUMANTH R S | 2000 | Fluoride2000，，33： | 1 |
| 12 | Particle incorporation by melt stirring for the production of metal-matrix composites 显示文摘 | Irons G A | 1993 | J Mater Sci1993，28，： | 1 |
| 13 | Three-dimensional aspects of formulation excipients in drug discovery:a critical assessment on orphan excipients,matrix effects and drug interactions显示文摘Formulation/pharmaceutical excipients play a major role in formulating drug candidates,with the objectives of ease of administration,targeted delivery and complete availability.Many excipients used in pharmaceutical formulations are orphanized in preclinical drug discovery.These orphan excipients could enhance formulatability of highly lipophilic compounds.Additionally,they are safe in preclinical species when used below the LD50 values.However,when the excipients are used in formulating compounds with diverse physico-chemical properties,they pose challenges by modulating study results through their bioanalytical matrix effects.Excipients invariably present in study samples and not in the calibration curve standards cause over-/under-estimation of exposures.Thus,the mechanism by which excipients cause matrix effects and strategies to nullify these effects needs to be revisited.Furthermore,formulation excipients cause drug interactions by moderating the pathways of drug metabolizing enzymes and drug transport proteins.Although it is not possible to get rid of excipient driven interactions,it is always advised to be aware of these interactions and apply the knowledge to draw meaningful conclusions from study results.In this review,we will comprehensively discuss a)orphan excipients that have wider applications in preclinical formulations,b)bioanalytical matrix effects and possible approaches to mitigating these effects,and c)excipient driven drug interactions and strategies to alleviate the impacts of drug interactions. | Vijayabhaskar Veeravalli Hanumanth Srikanth Cheruvu Pratima Srivastava Lakshmi Mohan Vamsi Madgula | 2020 | Journal of Pharmaceutical Analysis2020，10，6： | 0 |
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