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174篇 您的检索式：作者名="Hansen JM"

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	题名	作者	年代	出处	被引量
1	Interferon-γ inhibits ghrelin expression and secretion via a somatostatin-mediated mechanism显示文摘AIM:To investigate if and how the proinflammatory cytokine interferon γ(IFNγ) affects ghrelin expression in mice.METHODS:The plasma concentration of ghrelin,andgastric ghrelin and somatostatin expression,were examined in wild-type mice and mice infected with Helicobacter pylori(H.pylori).Furthermore,ghrelin expression was examined in two achlorhydric mouse models with varying degrees of gastritis due to bacterial overgrowth.To study the effect of IFNγ alone,mice were given a subcutaneous infusion of IFNγ for 7 d.Finally,the influence of IFNγ and somatostatin on the ghrelin promoter was characterized.RESULTS:H.pylori infection was associated with a 50% reduction in ghrelin expression and plasma concentration.Suppression of ghrelin expression was inversely correlated with gastric inflammation in achlorhdyric mouse models.Subcutaneous infusion of IFNγ suppressed fundic ghrelin mRNA expression and plasma ghrelin concentrations.Finally,we showed that the ghrelin promoter operates under the control of somatostatin but not under that of IFNγ.CONCLUSION:Gastric infection and inflammation is associated with increased IFNγ expression and reduced ghrelin expression.IFNγ does not directly control ghrelin expression but inhibits it indirectly via somatostatin.	Jesper AB Strickertsson Kristina BV DΦssing Anna JM Aabakke Hans-Olof Nilsson Thomas VO Hansen Ulrich Knigge Andreas Kjr Torkel Wadstrm Lennart Friis-Hansen	2011	World Journal of Gastroenterology2011，17，26：	2
2	Thl and Thl7 ceils: adversaries and collaborators显示文摘	Damsker JM Hansen AM Caspi RK	2010	Ann N Y Acad Sci2010，1183，1：	1
3	The importance of caloric re-striction in the early improvements in insulin sensitivity after Roux-en-Y gastric bypass surgery显示文摘	Isbell JM Tamboli RA Hansen EN	2010	Diabetes Care2010，33，7：	1
4	The role of PK/PD parameters to avoid selection and increase of resistance:mutant prevention concentration显示文摘	Blondeau JM Hansen G Metzler K	2004	J Chemother2004，16，3：	1
5	Detection of Campylobacter concisus and other Campylobaeter species in colonic biopsies from adults with ulcerative colitis 显示文摘	Mukhopadhya I Thomson JM Hansen R	2011	PLoS One2011，6，21：	1
6	Repeat CT imaging and re- planning during the course of IMRT for head - and - neck cancer 显示文摘	Hansen EK Bueel MK Quivey JM	2006	Int J Radiat Oncol Biol Phys2006，64，2：	1
7	A replicon-based bioassay for the measurement of interferons in patients with chronic hepatitis C显示文摘	Vrolijk JM Kaul A Hansen BE	2003	J Virol Methods2003，110，2：	1
8	Eight - year clinical and ra- diological follow- up of the Bryan cervical disc arthroplasty 显示文摘	Quan GM Vital JM Hansen S	2011	Spine2011，8，：	1
9	Oxidative stress as a mechanism of teratogenesis显示文摘	Hansen JM	2006	Birth Defects Res C Embryo Today2006，78，4：	1
10	Repeat CT imaging and replanning during the course of IMRT for head-and-ncck cancer 显示文摘	Hansen EK Bucci MK Quivey JM	2006	Int J Radiat Oncol Bial Phys2006，64，：	1
11	The transplanted human kidney does not achieve functional reinnervation显示文摘	Hansen JM Abildgaard U Fogh-Andersen N		0，，：	1
12	Eight-year clinical and radiological follow-up of the bryan cervical disc arthroplasty 显示文摘	Quan GM Vital JM Hansen S	2011	Spine2011，36，8：	1
13	Repeat CT imaging and replanning during during the course of IMRT for head-and-neck cancer显示文摘	Hansen EK Bucci MK Quivey JM	2006	Int J Radiat Oncol Biol Phys2006，64，：	1
14	Evaluation of a radioimmunoassay and establishment of a reference interval for salivary cortisol in healthy subjects in Denmark显示文摘	Hansen AM Garde AH Christensen JM	2003	Scand J Clin Lab Invest2003，63，4：	1
15	Calcitonin Gene-relat- edpeptide does not cause migraine attacks in patients with famil- ialhemiplegic migraine显示文摘	Hansen JM Thomsen LL Jes Olesen	2011	Headache2011，51，4：	1
16	Nuclear and mitochondrial compartmentation of oxidative stress and redox signaling显示文摘	Hansen JM Go YM Jones DP	2006	Annu Rev Pharmacol Toxicol2006，46，4：	1
17	Trigger factors for familial hemiplegic migraine 显示文摘	Hansen JM Hange AW Ashina M	2011	Cephalalgia2011，31，12：	1
18	Risk stratification of patientssuspected of coronary artery disease:Comparison of five differentmodels显示文摘	Jensen JM Voss M Hansen VB	2012	Atherosclerosis2012，220，2：	1
19	Evaluation of a radioimmunoassay and establishment of a reference interval for salivary cortisol in healthy subjects in Denmark显示文摘	Hansen AM Garde AH Christensen JM		0，，04：	1
20	Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation 显示文摘	Imhoff BR Hansen JM	2010	Cell Biol Toxicol2010，26，：	1

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