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42篇 您的检索式:作者名="Hanoun"
    题名 作者 年代 出处 被引量
1MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer显示文摘Despite tremendous efforts from scientists and clinicians worldwide, pancreatic adenocarcinoma(PDAC) remains a deadly disease due to the lack of early diagnostic tools and reliable therapeutic approaches. Consequently, a majority of patients(80%) display an advanced disease that results in a low resection rate leading to an overall median survival of less than 6 months. Accordingly, robust markers for the early diagnosis and prognosis of pancreatic cancer, or markers indicative of survival and/or metastatic disease are des-perately needed to help alleviate the dismal prognosis of this cancer. In addition, the discovery of new therapeutic targets is mandatory to design effective treatments. In this review, we will highlight the translational studies demonstrating that microRNAs may soon translate into clinical applications as long-awaited screening tools and therapeutic targets for PDAC.Marion Gayral Sébastien Jo Naima Hanoun Alix Vignolle-Vidoni Hubert Lulka Yannick Delpu Aline Meulle Marlène Dufresne Marine Humeau Maёl Chalret du Rieu Barbara Bournet Janick Sèlves Rosine Guimbaud Nicolas Carrère Louis Buscail Jérome Torrisani Pierre Cordelier 2014World Journal of Gastroenterology2014,20,32:4
2A comparison of the treatment effects of the Forsus fatigue resistance de- vice and the twin block appliance in patients with class II malocclusions显示文摘Hanoun A A1-Jewair TS Tabbaa S 2014Clin Cosmet Investig Dent2014,6,2:1
3Anterior skull base reconstruction显示文摘Hanoun G Sova M Smrcka M 2006Rozhl Chir2006,85,12:1
4Formaldehyde measurements in libraries: Comparison between infrared diode laser spectroscopy and a DNPH-derivatization method 显示文摘Hanoune B LeBris T Allou L 2006Atmospheric Environment2006,40,30:1
5Long-term treatment with the antioxidant drug EGb761 at senescence restored some neurobehavioral effects of chronic uhramild stress exposure seen in young mice 显示文摘Pardon M C Hanoun N Perez-Diaz F 2004Neurobiol Aging2004,25,8:1
6The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis显示文摘Hanoun N Delpu Y Suriawinata AA 0,,:1
7Formaldehyde measurements in libraries: Comparison between infrared diode laser spectroscopy and a DNPH-derivatization method显示文摘HANOUNE B LEBRISA T ALLOU L 2006Atmospheric Environment2006,40,:1
8Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene显示文摘Eddahibi S Hanoun N Lanfumey L 2000J Clin Invest2000,105,:1
9Blockade of β1-and desensitization of β2-adrenoceptors reduce isoprenaline-induced cardiac fibrosis显示文摘Fazia Brouri Naima Hanoun Odile Mediani 2004Eur J Pharmacol2004,485,:1
10Anterior skull base reconstruction 显示文摘Hanoun G Sova M Smrcka M 2006Rozhl Chit2006,85,12:1
11Anterior skull base reconstruction 显示文摘HANOUN G SOVA M SMRCKA M 2006Rozhl Chir2006,85,12:1
12Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice显示文摘Jzikki M Hanoun N Marcos E 2007Am J Physiol Lung Cell Mol Physiol2007,293,4:1
13The Role of the 3' untranslated region in the post -transcriptional regulation of KLF6 gene expression in hepatocellutar carcinoma显示文摘DIAB T HANOUN N BUREAU C 2013Canc- ers (Basel)2013,6,1:1
14The SV2 variant of KLF6 is downregulated in hepatocellular carcinoma and displays anti-proliferative and pro-apoptotic functions显示文摘Hanoun N Bureau C Diab T 2010J Hepatol2010,53,:1
15A Step Toward NOTES Total Mesorectal Excision for Rectal Cancer: Endoscopic Transanal Proctectomy显示文摘Jean-Jacques Tuech Mehdi Karoui Bernard Lelong Cécile De Chaisemartin Valerie Bridoux Gilles Manceau Jean-Robert Delpero Laurent Hanoun Francis Michot 2015Annals of Surgery2015,,2:1
16Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase显示文摘Defer N Best-Belpomme M Hanoune J 2000Am J Physiol Renal Physiol2000,279,3:1
17The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis显示文摘Hanoun N Delpu Y Suriawinata AA 0,,07:1
18Anterior skull base recon- struction 显示文摘Hanoun G Sova M Smrcka M 2006Rozhl Chir2006,85,12:1
19Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase显示文摘Defer N Best-Belpomme M Hanoune J 2000Am J Physiol Ren Physio12000,279,:1
20Regulation and role of adenylyl cyclase isoforms 显示文摘Hanoune J Defer N 2001Annu Rev Pharmacol Toxicol2001,41,:1
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