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10篇 您的检索式:作者名="Delpu"
    题名 作者 年代 出处 被引量
1MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer显示文摘Despite tremendous efforts from scientists and clinicians worldwide, pancreatic adenocarcinoma(PDAC) remains a deadly disease due to the lack of early diagnostic tools and reliable therapeutic approaches. Consequently, a majority of patients(80%) display an advanced disease that results in a low resection rate leading to an overall median survival of less than 6 months. Accordingly, robust markers for the early diagnosis and prognosis of pancreatic cancer, or markers indicative of survival and/or metastatic disease are des-perately needed to help alleviate the dismal prognosis of this cancer. In addition, the discovery of new therapeutic targets is mandatory to design effective treatments. In this review, we will highlight the translational studies demonstrating that microRNAs may soon translate into clinical applications as long-awaited screening tools and therapeutic targets for PDAC.Marion Gayral Sébastien Jo Naima Hanoun Alix Vignolle-Vidoni Hubert Lulka Yannick Delpu Aline Meulle Marlène Dufresne Marine Humeau Maёl Chalret du Rieu Barbara Bournet Janick Sèlves Rosine Guimbaud Nicolas Carrère Louis Buscail Jérome Torrisani Pierre Cordelier 2014World Journal of Gastroenterology2014,20,32:4
2The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis显示文摘Hanoun N Delpu Y Suriawinata AA 0,,:1
3The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis显示文摘Hanoun N Delpu Y Suriawinata AA 0,,07:1
4DNA methylation and cancerdiagnosis显示文摘Delpu Y Cordelier P Cho WC 2013Int J Mol Sci2013,14,15:1
5Genetic and Epigenetic Alterations in Pancreatic Carcinogenesis显示文摘Yannick Delpu Naima Hanoun Hubert Lulka Flavie Sicard Janick Selves Louis Buscail Jerome Torrisani Pierre Cordelier 2011Current Genomics2011,,1:1
6DNA methylation and cancer diagnosis显示文摘Delpu Y Cordelier P Cho WC 2013Int J Mol Sci2013,14,15:1
7DNA methylation and cancer diagnosis显示文摘Delpu Y Cordelier P Cho W C 2013Int J Mol Sci2013,14,15:1
8The silencing ofmicroRNA 148a production by DNA hypermethylation is anearly event in pancreatic carcinogenesis 显示文摘Hanoun N Delpu Y Suriawinata AA 2010Clin Chem2010,56,7:1
9The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis显示文摘Hanoun N Delpu Y Suriawinata AA 2010Clin Chem2010,56,7:1
10The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis显示文摘Hanoun N Delpu Y Suriawinata AA 0,,:1
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