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| 1 | Clinical decision support for drug related events: Moving towards better prevention显示文摘Clinical decision support(CDS) systems with automated alerts integrated into electronic medical records demonstrate efficacy for detecting medication errors(ME) and adverse drug events(ADEs). Critically ill patients are at increased risk for ME, ADEs and serious negative outcomes related to these events. Capitalizing on CDS to detect ME and prevent adverse drug related events has the potential to improve patient outcomes. The key to an effective medication safety surveillance system incorporating CDS is advancing the signals for alerts by using trajectory analyses to predict clinical events, instead of waiting for these events to occur. Additionally, incorporating cutting-edge biomarkers into alert knowledge in an effort to identify the need to adjust medication therapy portending harm will advance the current state of CDS. CDS can be taken a step further to identify drug related physiological events, which are less commonly included in surveillance systems. Predictive models for adverse events that combine patient factors with laboratory values and biomarkers are being established and these models can be the foundation for individualized CDS alerts to prevent impending ADEs. | Sandra L Kane-Gill Archita Achanta John A Kellum Steven M Handler | 2016 | World Journal of Critical Care Medicine2016，5，4： | 2 |
| 2 | Use of the piggyBac transposon for germline transformation of insects 显示文摘 | Handler A M | 2002 | Insect Biochemistry and Molecular Biology2002，32，： | 1 |
| 3 | Use of the piggyBac tmnsposon for germ-line transformation of insects 显示文摘 | HANDLER A M | 2002 | Insect Biochemistry and Molecular Bidogy2002，32，10： | 1 |
| 4 | Temporal relationship of hepatobiliary function and morphology in rats following alphanaphylisothiocy-anate(ANIT) administration显示文摘 | Kossor D C Meunier P C Handler J A | 1993 | Toxicol Applphamacol1993，119，： | 1 |
| 5 | The lepidopter an transposon vector, piggyBac, mediates germline transforma- tion in the Mediterranean fruitfly 显示文摘 | Handler A M McCombs S D Fraser M J | 1998 | Proe Natl Aead Sei USA1998，95，13： | 1 |
| 6 | The lepidopteran transposon vector,piggyBac ,mediates germ-line transformation in the Med- iterranean fruit fly 显示文摘 | HANDLER A M MCCOMBS S D FRASER M J | 1998 | Science Geneties1998，195，： | 1 |
| 7 | Germline transponmation of Drosophilia melanogaster with the piggyBac transposon vector显示文摘 | HANDLER A M HARRELL II R A | 1999 | Insect Mol Biol1999，8，4： | 1 |
| 8 | Salivary gland neoplasms in children: a10-year survey at The Children's Hospital of Philadelphia显示文摘 | Kessler A Handler SD | 1994 | Int J Pediatr Otorhinolaryngol1994，29，3： | 1 |
| 9 | A stable genomic source of P element transposase in drosophila melanogaster and related drosophilids显示文摘 | Sheliachu P Gomez Alfres M Handler | 1991 | Mol gen genet1991，，225： | 1 |
| 10 | The sidely conserved Era G-protein containis an RNA-binding domain required for Era function in vivo显示文摘 | Johnstone B H Handler A A Chao D K | 1999 | Mol Microbiol1999，33，6： | 1 |
| 11 | Highly similar piggyBae elements in Bactrocera that share a common lineage with elements in noctuid moths 显示文摘 | Handler A M Zimowska G J Armstrong K F | 2008 | Insect Molecular Biology2008，17，4： | 1 |
| 12 | Proterozoic lithosphere in Marie Byrd Land,West Antarctica:Re-Os systematics of spinel peridotite xenoliths显示文摘 | Wysoczanski R J Gamble J A | 2003 | Chemical Geology2003，196，： | 1 |
| 13 | Intracranial germ cell tumors:a single institution experience and review of the literature显示文摘 | SMITH A A WENG E HANDLER M | 2004 | J Neurooncol2004，68，2： | 1 |
| 14 | The Widely Conserved Era G-protein Contains an RNA-binding Domain Required for Era Function in Vivo 显示文摘 | JOHNSTONE B H HANDLER A A CHAO D K | 1999 | Mol Microbiol1999，33，： | 1 |
| 15 | A new method for classifying pat- terns of prenatal care utilization using cluster analysis 显示文摘 | Rosenberg D Handler A Furner S | 2004 | Matem Child Health2004，8，1： | 1 |
| 16 | The lepidopteran transposon vector,piggyBac,mediates germ-line transformation in the Mediterranean fruit fly显示文摘 | Handler A M McCombs S D Fraser M J | 1998 | Proc Natl Acad Sci USA1998，95，13： | 1 |
| 17 | Direct numerical simulation of the turbulent channel flow of a polymer solution 显示文摘 | Sureshkumar R Beris A N Handler R A | 1997 | Phys Fluids1997，9，： | 1 |
| 18 | Note on the cancellation of contaminating noise in the measurement of turbulent wall pressure fluctuations显示文摘 | HORNE M P HANDLER R A | 1991 | Experiments in Fluids1991，，12： | 1 |
| 19 | Intraeranial germcell tumors:a single institution experience and review of the titerature显示文摘 | Weng E Handler M | 2004 | Jnenroonce 12004，68，2： | 1 |
| 20 | Platinum stable isotope analysis of geological standard reference materials by double-spike MC-ICPMS 显示文摘 | Creech J B Baker J A Handler M R Bizzarro M | 2014 | Chemical Geology2014，363，： | 1 |
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