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1Tobacco Transcription Factors NtMYC2a and NtMYC2b Form Nuclear Complexes with the NtJAZ1 Repressor and Regulate Multiple Jasmonate-lnducible Steps in Nicotine Biosynthesis显示文摘关於生命、不能生活的应力在栽培烟草(Nicotiana tabacum L.) 导致烟碱和相关 pyridine 碱的生合成的 jasmonic 酸(JA ) 和它的衍生物和激活的提高的层次。在 JA 应答的基因之中是 NtPMT1a,编码 putrescine N 甲基 transferase,在烟碱形成的关键规章的酶。我们描绘了三基因(NtMYC2a, b, c ) 其表达式被 JA 和那很快明确地导致的编码基本 helix-loop-helix (bHLH ) 抄写因素(TF ) 由绑定激活 JA 可诱导的 NtPMT1a 表示在 NtPMT1a 倡导者在以内的一个 G 盒子主题在 vivo 并且在 vitro 试金。用 split-YFP 试金,我们进一步证明当 JA 不在时, NtMYC2a 和 NtMYC2b 与 NtJAZ1 抑压者表现为原子建筑群。 RNA 干扰( RNAi )调停了在在编码涉及烟碱和次要的碱生合成的另外的酶的抄本的JA可诱导的 NtPMT1a 抄本层次,以及减少的层次的重要减少的 NtMYC2a 和 NtMYC2b 表示结果击倒,包括在编码通常认为的烟碱 synthase 基因 NtA662 的抄本的水平的8090%减小。相反, NtMYC2a 和 NtMYC2b 的宫外的 overexpression 没当面在 NtPMT1a 表示上有效果或外长地增加的 JA 的缺席。这些数据建议那 NtMYC2a, b, c 是在烟碱 biosynthetic 小径的多重基因的 JA 可诱导的表示的要求的部件并且可以在 JA 回答的激活 additively 行动。Hong-Bo Zhang Marta T. Bokowiec Paul J. Rushton Sheng-Cheng Han Michael R Timko 2012Molecular Plant2012,5,1:47
2术前肌电图和脑干听觉诱发电位与面肌痉挛微血管减压术后迟发性面瘫发生的关系(英文)显示文摘Background Delayed facial palsy ( DFP) after microvascular decompression ( MVD) in patients with hemifacial spasm ( HFS) is not uncommon,but the cause remains unknown. Objectives To assess whether intraoperative electromyography ( EMG) and brainstem auditory evoked potential ( BAEP) can predict DFP after MVD. Methods Between September 2009 and February 2011 we examined 86 patients,9 of whom ( 10. 4% ) developed DFP after MVD on the same side. All patients underwent MVD and were followed - up for a median period of 13 months ( range 6-22) . We retrospectively examined intraoperative facial EMG and BAEP findings using our MVD patients' registry. We excluded secondary HFS and immediate postoperative facial palsy after MVD in this study. We assessed the prevalence and clinical characteristics of DFP and compared EMG and BAEP findings between DFP and non-DFP groups. Results: All pa- tients recovered completely,with a mean time to recovery of 37. 8 days ( range 22-57) . There were no significant differences between DFP and non - DFP patients in terms of the amplitude and latency of intraoperative EMG and BAEP. Conclusion The usefulness of intraoperative facial EMG and BAEP is limited and cannot predict DFP after MVD for HFS. We speculate that DFP after MVD is not associated with permanent nerve damage according to the EMG findings.Kim HJ Park YS Ryu JS Huh R Han I Shin DA Kim TG Cho KG Chung SS 2012中华神经外科疾病研究杂志2012,11,4:13
3Distribution of Crystal Organic Fertilizer-N in Soil-plant System显示文摘The distribution of crystal organic fertilizer, urea and compound fertilizer-N in soil and plant system was researched with 15N-trace under tobacco pot experiment. The results showed that the leaf yield of tobacco used crystal organic fertilizer was 23.1% and 14.6 % higher than that of urea and compound fertilizer treatments respectively. Compound fertilizer also resulted in higher yield of 8.5% comparing with the urea treatment. Nitrogen content of the plant from the crystal organic fertilizer treatment was 138.6% and 145.7% as high as that of the compound fertilizer and urea treatments respectively. The absorbed N from the organic fertilizer was 25.1% and 27.9% more than that from the compound fertilizer and urea respectively.However, the absorbed N from the soil with the organic fertilizer was 47.4% and 58.3% more than that with compound fertilizer and urea respectively. The N use efficiency of the organic fertilizer was 9.4% and 10.1%higher than that of the compound fertilizer and urea. It indicated that the crystal organic fertilizer not only had high N use efficiency, but also stimulated tobacco taking up more N from soil.LIU Yi-xin, HAN Yi-wang, WANG Yan-ting, HONG Li-fang XU Xi-min,TANG Shen, LIN Guan-ya and LIU Wu-ding(Department of Environmental Science , Institute of Earth and Space , University of Science and Technology of China , Hefei 230026 , P. R . China Department of Tobacco Science , University of Science and Technology of China , Hefei 230052 , P. R . China Department of Science , Technology and Education of Tobacco Monopoly Administration of China , Beijing 100052 , P. R . China Institute of Soil and Fertilizer , Yunnan Academy of Agricultural science , Kunmin 650231 , P. R . China Sanmin Tobacco Branch Company of Fujians , Sanmin 365010 , P. R . China Yongzhou Tobacco Branch Company of Hunan , Yongzhou 425000 , P. R . China Sinan Tobacco Company of Guizhou , Sinan 565100 , P. R . China Department of Resources , Environment and Agrochemistry , Huazhong Agricultural University, Wuhan 430070 , P.R.China) 2002Agricultural Sciences in China2002,1,9:8
4Impaired contractility and remodeling of the upper gastrointestinal tract in diabetes mellitus type-1显示文摘AIM: To investigate that both the neuronal function of the contractile system and structural apparatus of the gastrointestinal tract are affected in patients with longstanding diabetes and auto mic neuropathy. METHODS: The evoked esophageal and duodenal contractile activity to standardized bag distension was assessed using a specialized ultrasound-based probe. Twelve type-1 diabetic patients with autonomic neuropathy and severe gastrointestinal symptoms and 12 healthy controls were studied. The geometry and biomechanical parameters (strain, tension/stress, and stiffness) were assessed. RESULTS: The diabetic patients had increased frequency of distension-induced contractions (6.0 ± 0.6 vs 3.3 ± 0.5, P < 0.001). This increased reactivity was correlated with the duration of the disease (P = 0.009). Impaired coordination of the contractile activity in diabetic patients was demonstrated as imbalance between the time required to evoke the first contraction at the distension site and proximal to it (1.5 ± 0.6 vs 0.5 ± 0.1, P = 0.03). The esophageal wall and especially the mucosa-submucosa layer had increased thickness in the patients (P < 0.001), and the longitudinal and radial compressive stretch was less in diabetics (P <0.001). The esophageal and duodenal wall stiffness and circumferential deformation induced by the distensions were not affected in the patients (all P > 0.14). CONCLUSION: The impaired contractile activity with an imbalance in the distension-induced contractions likely reflects neuronal abnormalities due to autonomic neuropathy. However, structural changes and remodeling of the gastrointestinal tract are also evident and may add to the neuronal changes. This may contribute to the pathophysiology of diabetic gut dysfunction and impact on future management of diabetic patients with gastrointestinal symptoms.Jens BrΦndum FrΦkjΦr SΦren Due Andersen Niels EjskjΦr Peter Funch-Jensen AsbjΦrn Mohr Drewes Hans Gregersen 2007World Journal of Gastroenterology2007,13,36:8
5Electro-Pulse-Boring(EPB): Novel Super-Deep Drilling Technology for Low Cost Electricity显示文摘The inexhaustible heat deposit in great depths(5–10km) is a scientific fact. Such deposit occurs around the globe. Thereby,everybody is enabled to generate autonomously clean and renewable energy,ample electricity and heat. The economical exploration and exploitation of this superdeep geothermal heat deposit requires a novel drilling technique,because the currently only deep drilling method(Rotary) is limited to about 5km,due to the rising costs,depending exponentially on depth. Electro-pulse-boring(EPB) is a valuable option to Rotary drilling. EPB,originally investigated in Russia,is ready to be developed for industrialization. The feasibility of EPB is proven by many boreholes drilled up to 200 m in granite(crystalline). Estimates show outstanding low costs for drilling by EPB: 100 €/m for a borehole with a large diameter such as 20'(50 cm),independent on depth and applicable likewise for sediments and crystalline rocks,such as granite. The current rate of penetration(ROP) of 3 m per hour is planned to be augmented up to 35m per hour,and again,irrespective whether in sedimentary or crystalline formations. Consequently,a 10km deep borehole with 50 cm will ultimately be drilled within 12 days. EPB will create new markets,such as:(i) EPB shallow drilling for geotechnics,energy piles,measures in order to mitigate natural hazards,etc.,(ii) EPB deep drilling(3–5km) for hydro-geothermics,exploration campaigns etc. and(iii) EPB super-deep drilling(5–10km) for petro-geothermics,enabling the economic generation of electricity. The autonomous and unlimited supply with cost efficient electricity,besides ample heat,ensures reliably clean and renewable energy,thus,high supply security. Such development will provide a substantial relief to cope with the global challenge to limit the climate change below 2 oC. The diminution of fossil fuels,due to the energy transition in order to mitigate the climate change,implies likewise the decrease of air pollution.Hans O.Schiegg Arild Rdland Guizhi Zhu David A.Yuen 2015Journal of Earth Science2015,26,1:8
6Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk显示文摘AIM: To investigate the role that single nucleotide polymorphisms (SNPs) in the promoter of the tumour necrosis factor-alpha (TNF-α) gene play in the risk of inflammatory bowel diseases (IBDs) in a New Zealand population, in the context of international studies. METHODS: DNA samples from 388 patients with Crohn's disease (CD), 405 ulcerative colitis (UC), 27 indeterminate colitis (IC) and 201 randomly selected controls, from Canterbury, New Zealand were screened for 3 common polymorphisms in the TNF-α receptor: -238 G→A, -308 G→A and -857C→T, using a TaqmanR assay. A meta-analysis was performed on the data obtained on these polymorphisms combined with that from other published studies. RESULTS: Individuals carrying the -308 G/A allele had a significantly (OR = 1.91, χ2 = 17.36, P < 0.0001) increased risk of pancolitis, and a 1.57-fold increased risk (OR = 1.57, χ2 = 4.34, P = 0.037) of requiring a bowel resection in UC. Carrying the -857 C/T variant decreased the risk of ileocolonic CD (OR = 0.56, χ2 =4.32, P = 0.037), and the need for a bowel resection (OR = 0.59, χ2 = 4.85, P = 0.028). The risk of UC was reduced in individuals who were smokers at diagnosis, (OR = 0.48, χ2 = 4.86, P = 0.028). CONCLUSION: TNF-α is a key cytokine known to play a role in inflammatory response, and the locus for the gene is found in the IBD3 region on chromosome 6p21, known to be associated with an increased risk for IBD. The -308 G/A SNP in the TNF-α promoter is functional, and may account in part for the increased UC risk associated with the IBD3 genomic region. The -857 C/T SNP may decrease IBD risk in certain groups. Pharmaco- or nutrigenomic approaches may be desir- able for individuals with such affected genotypes.Lynnette R Ferguson Claudia Huebner Ivonne Petermann Richard B Gearry Murray L Barclay Pieter Demmers Alan McCulloch Dug Yeo Han 2008World Journal of Gastroenterology2008,14,29:7
7A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software packageYU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden 2001Chinese Science Bulletin2001,46,23:6
8Reprogramming fibroblasts into induced pluripotent stem cells with Bmil显示文摘Jai-Hee Moon June Seok Heo Jun Sung Kim Eun Kyoung Jun Jung Han Lee Aeree Kim Jonggun Kim Kwang Youn Whang Yong-Kook Kang Seungeun Yeo Hee-Joung Lim Dong Wook Han Dong-Wook Kim Sejong Oh Byung Sun Yoon Hans R Scholet Seungkwon You 2011Cell Research2011,21,9:6
9Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients.Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder 2009World Journal of Gastroenterology2009,15,9:6
10Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogenactivated protein kinase in mouse lung显示文摘Xin-qi PENG Mahendra DAMARLA Jarrett SKIRBALL Stephanie NONAS Xiao-ying WANG Eugenia J HAN Emile J HASAN Xuan CAO Adel BOUEIZ Rachel DAMICO Rubin M TUDER Alfred M SClUTO Dana R ANDERSON Joe GNGARCIA David A KASS Paul M HASSOUN Jun-tian ZHANG 2010Acta Pharmacologica Sinica2010,31,2:6
11Voltage rise mitigation for solar PV integration at LV grids Studies from PVNET.dk显示文摘Solar energy from photovoltaic(PV)is among the fastest developing renewable energy systems worldwide.Driven by governmental subsidies and technological development,Europe has seen a fast expansion of solar PV in the last few years.Among the installed PV plants,most of them are situated at the distribution systems and bring various operational challenges such as power quality and power flow management.The paper discusses the modelling requirements for PV system integration studies,as well as the possible techniques for voltage rise mitigation at low voltage(LV)grids for increasing PV penetration.Potential solutions are listed and preliminary results are presented.Guangya YANG Francesco MARRA Miguel JUAMPEREZ Søren Bækhøj KJÆR Seyedmostafa HASHEMI JacobØSTERGAARD Hans Henrik IPSEN Kenn H.B.FREDERIKSEN 2015Journal of Modern Power Systems and Clean Energy2015,3,3:5
12Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn’s disease: an open randomised trial显示文摘Geert D’Haens Filip Baert Gert van Assche Philip Caenepeel Philippe Vergauwe Hans Tuynman Martine De Vos Sander van Deventer Larry Stitt Allan Donner Severine Vermeire Frank J Van De Mierop Jean-Charles R Coche Janneke van der Woude Thomas Ochsenkühn Ad A 2008The Lancet2008,,9613:5
13Pathological and biochemical alterations of astrocytes in ovariectomized rats injected with D-galactose:A potential contribution to Alzheimer's disease processes显示文摘Astrocytes are implicated in the pathological changes of Alzheimer's disease. Our previous studies have demonstrated that estrogen deprivation and oxidative stress act synergistically to accelerate the progress of Alzheimer's disease. Long-term D-galactose injection combined with ovariectomy may serve as a rodent model for Alzheimer's disease. To address the potential contribution of astroglia to the Alzheimer's disease pathogenesis, we investigated pathological and biochemical alterations of astrocytes under this animal model. Ovadectomized rats injected with D-galactose for 2 weeks showed extensive localization of glial fibrillary acidic protein immunoreactive astrocytes and slightly elevated glutathione levels in the hippocampus without significant impairments in the water maze test and deficits of the cholinergic analyses, compared to the saline-injected rats. Ovariectomized rats injected with D-galactose for 6 weeks, however, exhibited degeneration of astrocytes and decreased glutathione levels in the hippocampus, accompanied with severe dysfunction of behavioral test and deficiency of cholinergic terminals. Electron microscopy further confirmed the pathological changes of astrocytes, especially in the aggregated area of synapse and brain microvessels. Consistent with degeneration of perivascular astrocytic endfeet, analysis of the horseradish peroxidase demonstrated an impairment of the blood-brain barrier permeability. These findings indicate that biochemical and pathological alterations of astrocytes may partially contribute to exacerbating neuronal deficits in the course of Alzheimer's disease. Restoring neuroprotective potential of astrocytes may be a useful therapeutic target for Alzheimer's disease and other neurodegenerative diseases.Hua, X. D. Lei, M. Ding, H. Han, Q. Y. Hu, G. Xiao, M. Nanjing Med Univ,Dept Anat Histol & Pharmacol,Jiangsu Prov Key Lab Neurodegenerat,Nanjing 210029,Peoples R China. 2008南京医科大学学报(自然科学版)2008,28,6:4
14Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c显示文摘AIM To determine whether successful treatment with direc-tacting antivirals(DAA) is associated with improvements in hemoglobin A1 c(HbA1 c) and if type 2 diabetes mellitus(T2 DM) or metabolic syndrome affects sustained virologic response(SVR).METHODS We performed a retrospective analysis of all hepatitis C virus(HCV) patients at the VA Greater Los Angeles Healthcare System treated with varying DAA therapy between 2014-2016. Separate multivariable logistic regression was performed to determine predictors of HbA1 c decrease ≥ 0.5 after DAA treatment and predictors of SVR 12-wk post treatment(SVR12).RESULTS A total of 1068 patients were treated with DAA therapy between 2014-2016. The presence of T2 DM or metabolic syndrome did not adversely affect SVR12. 106 patients had both HCV and T2 DM. Within that cohort,patients who achieved SVR12 had lower mean HbA1 c pre treatment(7.35 vs 8.60,P = 0.02),and lower mean HbA1 c post-treatment compared to non-responders(6.55 vs 8.61,P = 0.01). The mean reduction in HbA1 c after treatment was greater for those who achieved SVR12 than for non-responders(0.79 vs 0.01,P = 0.03). In adjusted models,patients that achieved SVR12 were more likely to have a HbA1 c decrease of ≥ 0.5 than those that did not achieve SVR12(adjusted OR = 7.24,95%CI: 1.22-42.94). CONCLUSION In HCV patients with T2 DM,successful treatment with DAA was associated with a significant reduction in HbA1 c suggesting that DAA may have a role in improving insulin sensitivity. Furthermore,the presence of T2 DM or metabolic syndrome does not adversely affect SVR12 rates in patients treated with DAA.Tien S Dong Elizabeth S Aby Jihane N Benhammou Jenna Kawamoto Steven-Huy Han Folasade P May Joseph R Pisegna 2018World Journal of Hepatology2018,10,9:4
15饲喂玉米秸秆和混合粗饲料日粮对荷斯坦奶牛乳脂肪酸组成的影响显示文摘本试验研究了调整日粮精粗比对奶牛乳脂中脂肪酸组成的影响,比较了玉米秸秆和优质粗饲料的饲喂效果。将24头荷斯坦奶牛(泌乳日龄136d±37d)分为2组,分别饲喂2种日粮,即高粗饲料日粮(MF日粮,日粮精粗比(F︰C)=60︰40),粗饲料来源为苜蓿干草、玉米青贮和羊草,以及以玉米秸秆为单一粗饲料来源的低粗饲料日粮(CS日粮,(F︰C)=40︰60)。试验期9周。试验期间测定产奶量、乳脂肪含量和乳脂肪中脂肪酸组成。日粮处理对产奶量和乳脂肪含量无影响,而干物质采食量(P<0.01)和乳脂肪产量(P<0.05)MF组均高于CS组。与CS组相比,饲喂MF日粮提高了总不饱和脂肪酸的摄入量及乳脂肪中C18:0和C18:3含量(P<0.01),然而,<16C脂肪酸含量下降(P<0.05)。乳中总饱和脂肪酸、单不饱和脂肪酸和多不饱和脂肪酸含量差异均不显著。MF组乳脂肪中总不饱和脂肪酸与其每日摄取量之比较CS组低,说明高比例粗饲料更易导致瘤胃氢化作用。Han R W 孙鹏 2014中国畜牧兽医2014,41,3:4
16Anisotropic plastic deformation behavior of as-extruded ZK60 magnesium alloy at room temperature显示文摘The anisotropic plastic deformation behavior of as-extruded ZK60 magnesium alloy at room tempera-ture (RT) was investigated by compressive and tensile testing in different directions, i.e. the loading axis oriented at 0°, 45° and 90° to the extrusion direction. The relationship between texture and plastic deformation behavior were examined. The results show that the extruded ZK60 alloy exhibits a strong ring fiber texture. The mechanical properties are strongly orientation dependent. In tension testing, the 0° specimen exhibited higher yield strength and lower elongation. In compression testing, however, ZK60 alloy exhibited almost the same yield strength in three directions. The anisotropic plastic defor-mation behavior is due to strong fiber texture and the lower symmetry of the hexagonal close packed (hcp) structure of ZK60 alloy. The correlation between texture and mechanical behaviour offers the possibility to improve the mechanical properties of magnesium alloy by optimization of the material production process.HANS J R 2009Science China(Technological Sciences)2009,52,1:4
17Solid-pseudopapillary tumor of the pancreatic tail显示文摘We report a case of the rare solid-pseudopapillary tumor of the pancreas. In contrast to other pancreatic tumors,the solid-pseudopapillary tumor has a favorable prognosis.The 60-year-old female patient we report on here was treated by left pancreatic resection combined with splenectomy for a non-metastasizing tumor of the pancreas. A solid-pseudopapillary tumor was found on histology. The patient had no signs of metastases at present.Since a microscopically invasive tumor growth is assumed,oncologically curative resection should be preferred vs the less radical enucleation. The rare solid-pseudopapillary tumor of the pancreas has a good prognosis after successful oncological resection.Frank Eder Hans-Ulrich Schulz Christoph R(o|¨)cken Hans Lippert 2005World Journal of Gastroenterology2005,11,26:4
18Development of Temperature-Humidity Independent Control Air-Conditioning Unit for Residential Buildings显示文摘Cooling panels are increasingly used in domestic residential buildings.To provide medium temperature cold water for the cooling panel,and dehumidify the indoor air simultaneously,a new kind of temperature-humidity independent control air-conditioning unit was developed for single residential house by utilizing multi-variable technology.First,the supply air temperature was studied to determine the proper supply air flow rate for the humidity control.Then,the energy consumption of different temperature-humidity independent control systems was studied.The analysis indicates that unity evaporating temperature can be used to handle the moisture load and sensible heat load in two evaporators.So the unit scheme was put forward.Two evaporators were used to produce medium temperature water and dry air separately,and electric expansion valves were used to control the refrigerant distribution between the two evaporators.Then,experimental work was carried out to investigate the influence of compressor frequency,refrigerant distribution on the dehumidification capacity,energy efficiency and refrigeration capacity.In the end,the paper concludes that both compressor frequency and refrigerant distribution can control the dehumidification capacity,but the former influences the EER more than the latter,while the latter influences the refrigeration capacity more than the former.We can find a proper running point at certain sensible and latent cooling load by adjusting both compressor frequency and electric expansion valve.The energy consumption of this kind of unit was estimated and compared with present room air conditioners,which shows that it can save about 41% cooling energy consumption.HAN Xing1,ZHANG Xu1,LIU Jin-tao2,GAO Si-yun2,KANG Yue2(1.Institute of HVAC & Gas,College of Mechanical Engineering,Tongji University,Shanghai 200092,China 2.Hisense R&D Center,Qingdao,266000,China) 2009湖南大学学报(自然科学版)2009,36,S1:3
19油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%.刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F 2021中华高血压杂志2021,29,2:3
20基因对于儿童肥胖的影响在小于胎龄儿童中或不重要显示文摘小于胎龄儿在日后的生活中面临着更高的患肥胖症和代谢性疾病的风险,目前认为这种风险主要与小于胎龄儿出生后生长加速有关。研究人员对奥克兰出生体重协作研究项目中的小于胎龄儿和适于胎龄儿做了研究,测量并计算这些儿童的BMI-Z评分,研究与成人肥胖相关的常见基因变异是否会与小于胎龄儿出生后生长加速有关。研究者将547名欧洲儿童(228名小于胎龄儿和319名适于胎龄儿)进行基因分型,他们被分为共计37个单核苷酸多态性(SNPs)候选基因。重复测量儿童的BMI,并以Z评分法评估肥胖程度。Dug Yeo Han Rinki Murphy Angharad R Morgan 郭婧 张帆 2013营养健康新观察2013,0,1:2
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