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| 1 | miR-221/222 activate the Wnt/β-catenin signaling to promote triple-negative breast cancer显示文摘 | Sanhong Liu Zifeng Wang Zukai Liu Shuo Shi Zhaoran Zhang Jiawei Zhang Haifan Lin | 2018 | Journal of Molecular Cell Biology2018,10,4: | 16 |
| 2 | piRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism显示文摘piRNAs,小非编码的 RNA 的一个类把蛋白质与 PIWI 联系了,在 germline 开发, transposon silencing,和 epigenetic 规定有宽广函数。在多样的有机体,从重复序列导出的 piRNAs 的一个子集经由在二 PIWI 蛋白质之间的相互影响被生产。这机制,称为的 “ ping-pong”周期,在初发的老鼠睾丸的 PIWI 蛋白质之中操作;然而,它在出生后的睾丸的参与留下逃犯。这里,我们证明成年阴囊的 piRNAs 是乒乓球机制的生产独立人士。我们在与 MILI 和 MIWI 联系的成年、出生后的发展中的睾丸识别了并且描绘 piRNAs 的大人口,在这些睾丸可检测的唯一的 PIWI 蛋白质。在为在他们的 piRNAs 之中的乒乓球机制的 MILI 和 MIWI 或顺序特征之间的相互作用都没在成年睾丸被检测。联系 MILI 、联系 MIWI 的 piRNAs 的多数在一样的 loci 以内从一样的 DNA 海滨发源。piRNAs 的两张人口为 5 ′ 被偏导;Uracil 然而并非为第 10 核苷酸位置,和显示上的腺嘌没有补充。而且在 Miwi 异种,联系 MILI 的 piRNAs 不是 downregulated,但是相反 upregulated。这些结果显示成年阴囊的 piRNAs 是主要,如果不只,由主要处理机制生产了而不是乒乓球机制。在这条主要小径,联系 MILI 、联系 MIWI 的 piRNAs 的生物的续生说可以为一样的先锋竞争;生产的 piRNAs 的类型趋于被可得到的先锋非有选择地在房间规定;并且在处理了成 piRNAs 以前,有 introns 的先锋趋于被拼接。 | Ergin Beyret Na Liu Haifan Lin | 2012 | Cell Research2012,22,10: | 7 |
| 3 | PIWI proteins and their interactors in piRNA biogenesis,germline development and gene expression显示文摘PIWI-interacting RNAs(piRNAs) are a complex class of small non-coding RNAs that are mostly 24–32nucleotides in length and composed of at least hundreds of thousands of species that speciically interact with the PIWI protein subfamily of the ARGONAUTE family. Recent studies revealed that PIWI proteins interact with a number of proteins, especially the TUDOR-domain-containing proteins, to regulate piRNA biogenesis and regulatory function. Current research also provides evidence that PIWI proteins and pi RNAs are not only crucial for transposon silencing in the germline, but also mediate novel mechanisms of epigenetic programming, DNA rearrangements, m RNA turnover, and translational control both in the germline and in the soma. hese new discoveries begin to reveal an exciting new dimension of gene regulation in the cell. | Hsueh-Yen Ku Haifan Lin | 2014 | National Science Review2014,1,2: | 6 |
| 4 | Two Na^+ and Cl^- Hyperaccumulators of the Chenopodiaceae显示文摘The authors found five sodium (Na+) and chloride (Cl-) hyperaccumulating halophytes in the Temperate Desert of Xinjiang, China and studied two of them (Suaeda salsa (L.) Pall. and Kalidium folium (Pall.) Moq.). K. folium and S. salsa had a NaCl content of 32.1% and 29.8%, respectively, on a dry weight basis. X-ray microanalysis of the Na+ in the vacuole, apoplasts and cytoplasm of the two plants indicated a ratio of 7.3:5.6:1.0 in K. folium and 7.3:6.6:1.0 in S. salsa. These data show that K. folium and S. salsa both have a high Na+ and Cl-accumulating capacity, which is related to high activity oftonoplast H+-ATPase and H+-PPase. | Ke-FuZHAO HaiFAN JieSONG Ming-XiaSUN Bao-ZengWANG Sheng-QiangZHANG I.A.UNGAR | 2005 | Journal of Integrative Plant Biology2005,47,3: | 5 |
| 5 | Progress on AlGaN-based solar-blind ultraviolet photodetectors and focal plane arrays显示文摘Solar-blind ultraviolet(UV)photodetectors(PDs)have attracted tremendous attention in the environmental,industrial,military,and biological fields.As a representative Ill-nitride material,AlGaN alloys have broad development prospects in the field of solar-blind detection due to their superior properties,such as tunable wide bandgaps for intrinsic UV detection.In recent decades,a variety of AlGaN-based PDs have been developed to achieve high-precision solar-blind UV detection.As integrated optoelectronic technology advances,AlGaN-based focal plane arrays(FPAs)are manufactured and exhibit outsta nding solar-blind imaging capability.Con sidering the rapid development of AlGaN detection techniques,this paper comprehensively reviews the progress on AlGaN-based solar-blind UV PDs and FPAs.First,the basic physical properties of AlGaN are presented.The epitaxy and p-type doping problems of AlGaN alloys are then discussed.Diverse PDs,including photoconductors and Schottky,metal-semiconductor-metal(MSM),p-i-n,and avalanche photodiodes(APDs),are dem on strated,and the physical mechanisms are analyzed to improve device performance.Additionally,this paper summarizes imaging technologies used with AlGaN FPAs in recent years.Benefit!ng from the development of AlGaN materials and optoelectronic devices,solar-blind UV detection technology is greeted with significant revolutions. | Qing Cai Haifan You Hui Guo Jin Wang Bin Liu Zili Xie Dunjun Chen Hai Lu Youdou Zheng Rong Zhang | 2021 | Light(Science & Applications)2021,10,6: | 4 |
| 6 | Microstructures and Properties of 550 MPa Grade High Strength Thin-walled H-beam Steel显示文摘The microstructures and mechanical properties of 550 MPa grade lightweight high strength thin-walled H-beam steel were experimentally studied. The experimental results show that the microstructure of the air-cooled H-beam steel sample is consisted of ferrite, pearlite and a small amount of granular bainites as well as fine and dispersive V(C,N) precipitates. The microstructure of the water-cooled steel sample is consisted of ferrite and bainite as well as a small amount of fine pearlites. The microstructure of the water-cooled sample is finer than that of the air-cooled sample with the average intercept size of the surface grains reaching to 3.5 μm. The finish rolling temperature of the thin-walled high strength H-beam steel is in the range of 750 ℃-850 ℃. The lower the finish rolling temperature and the faster the cooling rate, the finer the ferrite grains, the volume fraction of bainite is increased through water cooling process. Grain refinement strengthening and precipitation strengthening are used as major strengthening means to develop 550 MPa grade lightweight high strength thin- walled H-beam steel. Vanadium partially soluted in the matrix and contributes to the solution strengthening. The 550 MPa grade high-strength thin-walled H-beam steel could be developed by direct air cooling after hot rolling to fully meet the requirements of the target properties. | CHEN Jiping KANG Yonglin QIAN Jianqing LI Shengzhi QIAN Haifan | 2013 | Journal of Wuhan University of Technology(Materials Science)2013,28,6: | 2 |
| 7 | miwi , a Murine Homolog of piwi , Encodes a Cytoplasmic Protein Essential for Spermatogenesis显示文摘 | Wei Deng Haifan Lin | 2002 | Developmental Cell2002,,6: | 2 |
| 8 | Simulation of stationary Gaussian stochastic wind velocity field 显示文摘 | Ding Quanshun Zhu Ledong Xiang Haifan | 2006 | Wind and Structures2006,9,3: | 1 |
| 9 | Frequency regulation in alternation-current transports across metal to insulator transitions of thin film correlated perovskite nickelates显示文摘Although the metal to insulator transition(MIT)observed in d-band correlated metal oxides enables promising applications(e.g.,correlated logical devices and Mottronic devices),its present recognition is mainly limited on the direct current(DC)electrical transports.Up to date,the MIT from the perspective of alternation current(AC)transport and its potential electronic applications remains yet unclear.Herein,we demonstrate the frequency(f_(AC))dependence in the impedance(Z=Z’+iZ″)of typical MIT materials,such as thin film rare-earth nickelates(Re NiO_(3)),across the critical MIT temperature(T_(MIT)).Apart from the abrupt change in the impedance modulus(|Z|)across the critical temperature(T_(MIT))similar to the DC transport,the MIT also triggers non-continuous variation in the impedance phase(θ),and this enables the f_(AC)-regulations in the Z’-T tendencies(Z’=|Z|cosθ).At the critical f_(AC) range(e.g.,104-106 Hz),the con-versing variations in|Z|-T and cosθ-T across T_(MIT) result in non-monotonic delta-shape Z’-T tendency in Sm_(x) Nd_(1-x) NiO_(3),the full width half maximum of which is effectively narrowed compared to the situation with the absence of MIT.Further imparting lower or higher f_(AC) elevate the domination in|Z|-T and cosθ-T,respectively,but also enables abrupt Z’-T tendencies across T_(MIT) showing negative temperature coefficient of resistance(NTCR)or positive temperature coefficient of resistance(PTCR).By introducing f_(AC) as a new freedom,the MIT behavior can be more comprehensively regulated electronically,and this extends the vision in exploring the new electronic applications based on the correlated MIT materials from the AC perspective. | Haifan Li Fanqi Meng Yi Bian Xuanchi Zhou Jiaou Wang Xiaoguang Xu Yong Jiang Nuofu Chen Jikun Chen | 2023 | Journal of Materials Science & Technology2023,,17: | 1 |
| 10 | Alongwind static equivalent wind loads and responses of tall building: Part I: Unfavorable distributions of static equivalent wind loads 显示文摘 | Zhou Yin Gu Ming Xiang Haifan | 1999 | Journal of Wind Engineering and Industrial Aerodynamics1999,,79: | 1 |
| 11 | Refinements on aerodynamic stability analysis of super long-span bridges 显示文摘 | Xiang Haifan Ge Yaojun | 2002 | Journal of Wind Engineering and Industrial Aerodynamics2002,90,12131415: | 1 |
| 12 | NASAB: a finite element software for the nonlinear aerostatic stability analysis of cable-supported bridges显示文摘 | Cheng Jin Rucheng Xiao Xiang Haifan | 2003 | Advances in Engineering Software2003,34,: | 1 |
| 13 | The research and application progress of diagnosis of tumor markers for early primary liver cancer显示文摘 | Xie Xiaoming Xu Haifan | 2010 | Journal of Hai Nan Medical College2010,16,10: | 1 |
| 14 | Application of a reliability analysis model to bridge flutter under extreme winds 显示文摘 | Ge Yaojun Xiang Haifan Tanaka H | 2000 | Journal of Wind Engineering and Industrial Aerodynamics2000,86,23: | 1 |
| 15 | The Biogenesis and Function of PIWI Proteins and piRNAs: Progress and Prospect显示文摘 | Travis Thomson Haifan Lin | 2009 | Annual Review of Cell and Developmental Biology2009,,: | 1 |
| 16 | Nonlinear aerostatic and aerodynamic analysis of long-span suspension bridges considering wind-structure interactions显示文摘 | Zhang Xinjun Sun Bingnan Xiang Haifan | 2002 | Journalof Wind Engineering and Industrial Aerodynamics2002,90,9: | 1 |
| 17 | Nonlinear aerostatie and aerodynamic analysis of long-span cable-stayed bridges considering wind-structure interaetions显示文摘 | ZHANG Xinjun SUN Bingnan XIANG Haifan | 2002 | Journal of wind Engineering and Industrial Aerodynamics2002,90,9: | 1 |
| 18 | Identification of flutter derivatives of bridge decks 显示文摘 | Gu Ming Zhang Ruoxue Xiang Haifan | 2000 | Journal of Wind Engineering and Industrial Aerodynamics2000,84,2: | 1 |
| 19 | Simulation of stationary Gaussian stochastic wind velocity field 显示文摘 | Ding Quanshun Zhu Ledong Xiang Haifan | 2006 | Wind and Structures2006,9,3: | 1 |
| 20 | Simulation of stationary Gaussian stochastic wind velocity field 显示文摘 | Ding Quanshun Zhu Ledong Xiang Haifan | 2006 | Wind and Structures2006,9,3: | 1 |