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| 1 | Contribution of the Compass satellite navigation system to global PNT users显示文摘As one of the four global satellite navigation systems,Compass not only enhances satellite visibility and availability for positioning,navigation and timing (PNT) for users in China and the surrounding areas,but also improves PNT precision for global users.The improvements in satellite visibility and the dilution of precision are analyzed under GNSS compatibility and interoperation conditions.The contribution of the Compass satellite navigation system to global users,especially the benefits that users can acquire from the combination of Compass,GPS,GLONASS,and Galileo navigation systems,is analyzed using simulation data. | YANG YuanXi LI JinLong XU JunYi TANG Jing GUO HaiRong HE HaiBo | 2011 | Chinese Science Bulletin2011，56，26： | 90 |
| 2 | The recommendations of Chinese Parkinson’s disease and movement disorder society consensus on therapeutic management of Parkinson’s disease显示文摘Background:Parkinson’s disease(PD)is a chronic,progressive and debilitating disease,which affects over 2.5 million people in China.PD is characterized clinically by resting tremor,muscular rigidity,bradykinesia and postural instability.As the disease progresses,additional complications can arise such as non-motor and neurobehavioral symptoms.Pharmacological treatment and surgical intervention for PD have been implemented in China.Until 10 years ago,there was lack of standardization for the management of PD in different regions and among different physicians,leading to different treatment levels in different regions and different physicians.Since then,the Chinese Parkinson’s Disease and Movement Disorder Society have published three versions of guidelines for the management of PD in China,in 2006,2009 and 2014,respectively.Correspondingly,the overall level of treatment for PD in China improved.Objectives:To update the treatment guidelines based on current foreign and domestic practice guidelines and clinical evidence,and to improve the treatment options available to physicians in the management of PD.Summary:A variety of treatment recommendations in the treatment guidelines have been proposed,including physical activity and disease-modifying medication,which should be initiated at the early-stage of the disease.The principles of dosage titration should be followed to avoid acute adverse reactions to the drugs,to achieve a satisfactory clinical effect with a low dose and to reduce the incidence of long-term motor complications.Moreover,different treatment strategies should be considered at different stages of the disease.Importantly,treatment guidelines and personalized treatments should be valued equally.A set of treatment recommendations has been developed to assist physicians to improve and optimize clinical outcomes for patients with PD in China. | Shengdi Chen Piu Chan Shenggang Sun Haibo Chen Baorong Zhang Weidong Le Chunfeng Liu Guoguang Peng Beisha Tang Lijuan Wang Yan Cheng Ming Shao Zhenguo Liu Zhenfu Wang Xiaochun Chen Mingwei Wang Xinhua Wan Huifang Shang Yiming Liu Pingyi Xu Jian Wang Tao Feng Xianwen Chen Xingyue Hu Anmu Xie Qin Xiao | 2016 | Translational Neurodegeneration2016，5，1： | 23 |
| 3 | Microstructure and mechanical properties of hybrid fabricated 1Cr12Ni2WMoVNb steel by laser melting deposition显示文摘Laser melting deposition was carried out to deposit a 1Cr12Ni2WMoVNb steel bar on a wrought bar of same material. Room-temperature tensile properties of the hybrid fabricated 1Cr12Ni2WMoVNb steel sample were evaluated, and microstructure, fracture surface morphology, and hardness profile were analyzed by an optical microscope (OM), a scanning electron microscope (SEM), and a hardness tester. Results show that the hybrid fabricated 1Cr12Ni2WMoVNb steel sample consists of laser deposited zone, wrought substrate zone, and heat affected zone (HAZ) of the wrought substrate. The laser deposited zone has coarse columnar prior austenite grains and fine well-aligned dendritic structure, while the HAZ of the wrought substrate has equiaxed prior austenite grains which are notably finer than those in the wrought substrate zone. Besides, austenitic transformation mechanism of the HAZ of the wrought substrate is different from that of the laser deposited zone during the reheating period of the laser deposition, which determines the different prior austenite grain morphologies of the two zones. Microhardness values of both the laser deposited zone and the HAZ of the wrought substrate are higher than that of the wrought substrate zone. Tensile properties of the hybrid fabricated 1Cr12Ni2WMoVNb steel sample are comparable to those of the wrought bar, and fracture occurs in the wrought substrate zone during the tensile test. | Wang Yudai Tang Haibo Fang Yanli Wang Huaming | 2013 | Chinese Journal of Aeronautics2013，26，2： | 15 |
| 4 | Theoretical analysis on water-inrush mechanism of concealed collapse pillars in floor显示文摘以便从机械看法学习隐藏的倒塌支柱的水流入机制,为倒塌支柱的水流入的一个机械模型在这份报纸基于有弹性的力学的厚板理论被建立了。在水压力和批评的水压力的表示的行动下面由解决这为抗水的岩石阶层的变丑建模因为倒塌支柱水流入被获得了研究结果显示那:抗水的阶层的边界条件和力量在影响倒塌支柱的水流入起重要作用。批评水流入压力被相对厚度和抗水的阶层的绝对厚度决定。 | Tang Junhua Bai Haibo Yao Banghua WU YU | 2011 | Mining Science and Technology2011，21，1： | 12 |
| 5 | Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases显示文摘Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of novel therapeutics.In this study,we report the autopsy findings from the lungs and lymphatic organs of 12 COVID-19 decedents—findings that evaluated histopathological changes;immune cell signature and inflammatory factor expression in the lungs,spleen and lymph nodes.Here we show that the major pulmonary alterations included diffuse alveolar damage,interstitial fibrosis and exudative inflammation featured with extensive serous and fibrin exudates,macrophage infiltration and abundant production of inflammatory factors(IL-6,IP-10,TNFo?and IL-I f).The spleen and hilar lymph nodes contained lesions with tissue structure disruption and immune cell dysregulation,including lymphopenia and macrophage accumulation.These findings provide pathological evidence that links injuries of the lungs and lymphatic organs with the fatal systematic respiratory and immune malfunction in critically ill COVID-19 patients. | Qian Liu Yu Shi Jun Cai Yaqi Duan Rongshuai Wang Hongyan Zhang Qiurong Ruan Jiansha Li Lei Zhao Yifang Ping Rong Chen Liang Ren Xiaochun Fei Heng Zhang Rui Tang Xi Wang Tao Luo Xindong Liu Xuequan Huang Zhenhua Liu Qilin Ao Yong Ren Jing Xiong Zhicheng He Haibo Wu Wenjuan Fu Pengnan Zhao Xinwei Chen Guoqiang Qu Yunyun Wang Xi Wang Jia Liu Dongfang Xiang Sanpeng Xu Xiaowei Zhou Qingrui Li Jinghong Ma Heng Li Jie Zhang Sizhe Huang Xiaohong Yao Yiwu Zhou Chaofu Wang Dingyu Zhang Guoping Wang Liang Liu Xiu-Wu Bian | 2020 | National Science Review2020，7，12： | 6 |
| 6 | Effect of cream, prepared with Tripterygium wilfordii Hook F and other four medicinals, on joint pain and swelling in patients with rheumatoid arthritis: a double-blinded, randomized, placebo controlled clinical trial显示文摘OBJECTIVE: To investigate the effectiveness a cream onjoint pain and swelling in patients with rheumatoid arthritis(RA). The cream, topically used, in was prepared with Tripterygium wilfordii Hook F(TwHF), Mangxiao(Nalrii Sulfas), Chuanxiong(Rhizoma Chuanxiong), stir-frying with liquid adjuvant Ruxiang(Olibanum), and stir-frying with liquid adjuvant Moyao(Myrrh).METHODS: Patients were 1∶1 randomized to addon TwHF cream twice a day or placebo for 4 weeks.The primary endpoint was achievement rate of20% improvement in American College of Rheuma-tology criteria(ACR20) at week 4. Secondary endpoints were ACR50, 28-joint count Disease Activity Score(DAS28) improvement and safety profiles.Statistical analyses were performed using intention to treat analysis(ITT) set.RESULTS: A total of 70 active RA patients were enrolled. At week 4, the ACR20 was 34.3%(12/35) in TwHF cream group and 11.4%(4/35) in placebo group(P = 0.015). Similarly, a higher ACR50 responder proportion was seen in TwHF cream group with 17.1%(6/35) comparing to it in placebo group with 2.9%(1/35)(P = 0.046). The TwHF cream group also had more improvement than the placebo group on DAS28-ESR(1.1 vs 0.5, P = 0.001), DAS28-CRP(1.4 vs 0.7, P = 0.001), tender joint count(5.5 vs2.6, P = 0.018), swollen joint count(3.5 vs 1.6, P =0.003) and Physician's global assessment(25.8 vs13.0, P = 0.002), as well as C-reactive protein(11.2 vs 2.7, P = 0.048). Except 2 skin allergy events in TwHF cream group, no other substantive adverse events were observed.CONCLUSION: On the short term, TwHF cream is likely to be an effective and safety complimentary treatment in patients with active RA. | Jiao Juan Wei Chengchung Tang Xiaopo Gong Xun Yin Haibo Jiang Quan | 2019 | Journal of Traditional Chinese Medicine2019，39，1： | 6 |
| 7 | Efficient Carbon-Based CsPbBr_3 Inorganic Perovskite Solar Cells by Using Cu-Phthalocyanine as Hole Transport Material显示文摘Metal halide perovskite solar cells(PSCs) have attracted extensive research interest for next-generation solution-processed photovoltaic devices because of their high solar-to-electric power conversion efficiency(PCE)and low fabrication cost. Although the world's best PSC successfully achieves a considerable PCE of over 20% within a very limited timeframe after intensive efforts, the stability, high cost, and up-scaling of PSCs still remain issues. Recently, inorganic perovskite material, CsPbBr_3, is emerging as a promising photo-sensitizer with excellent durability and thermal stability, but the efficiency is still embarrassing. In this work, we intend to address these issues by exploiting CsPbBr_3 as light absorber, accompanied by using Cu-phthalocyanine(CuPc) as hole transport material(HTM) and carbon as counter electrode. The optimal device acquires a decent PCE of 6.21%, over 60% higher than those of the HTM-free devices. The systematic characterization and analysis reveal a more effective charge transfer process and a suppressed charge recombination in PSCs after introducing CuPc as hole transfer layer. More importantly, our devices exhibit an outstanding durability and a promising thermal stability, making it rather meaningful in future fabrication and application of PSCs. | Zhiyong Liu Bo Sun Xingyue Liu Jinghui Han Haibo Ye Tielin Shi Zirong Tang Guanglan Liao | 2018 | Nano-Micro Letters2018，10，2： | 5 |
| 8 | Tectonics-palaeogeomorphology in rift basins: controlling effect on the sequence architecture显示文摘The relationship between deposition and tectonics of sedimentary basins has been a significant subject in recent years.Using typical rift basins such as the Nanpu Sag as an example,combined with the analysis of the tectonics-palaeogeomorphology of basins,we undertook a detailed study of the differences of the third-order sequences in different basins,the combination of depositional systems within the sequence framework and the distribution of depocenters and subsidence centers.Our results revealed a significant relationship between the tectonics-palaeogeomorphology of rift basins and the filling styles of sedimentary sequences.The basin structure plays a primary role in controlling the development of the third-order sequences and the boundary of these sequences is easily formed in basins with gentle slopes,shallow water and a small area.The characteristics of the tectonics-palaeogeomorphology of rift basins are dominated by half-grabens of extensional faults,which affect the temporal and spatial combination of sedimentary systems within the sequences as well as the distribution of depocenters and subsidence centers.Based on the development rules of the faults dominating the half-grabens of extensional faults,rift basins are classified into two types: the single fault segmented-linkage type and the multi-fault combination type.The main controlling factors of the temporal and spatial combination of sedimentary systems and the distribution of depocenters and subsidence centers in different basins are different.The characteristics of early segmentation and later linkage of the faults play a critical role in controlling the sedimentary system combination within the sequence framework and the temporal and spatial differences of depocenters and subsidence centers of the single fault segmented-linkage rift basins,while the differences in fault activities are the dominating factors of the multi-fault combination rift basins. | Ji Hancheng Jia Haibo Sun Simin Chen Liang Tang Yang Chen Wei Geng Yikai Zhou Hang | 2013 | Petroleum Science2013，10，4： | 3 |
| 9 | In situ monitoring of the structural change of microemulsions in simulated gastrointestinal conditions by SAXS and FRET显示文摘Microemulsions are promising drug delivery systems for the oral administration of poorly watersoluble drugs. However, the evolution of microemulsions in the gastrointestinal tract is still poorly characterized,especially the structural change of microemulsions under the effect of lipase and mucus. To better understand the fate of microemulsions in the gastrointestinal tract, we applied small-angle X-ray scattering(SAXS) and fluorescence resonance energy transfer(FRET) to monitor the structural change of microemulsions under the effect of lipolysis and mucus. First, the effect of lipolysis on microemulsions was studied by SAXS, which found the generation of liquid crystalline phases. Meanwhile, FRET spectra indicated micelles with smaller particle sizes were generated during lipolysis, which could be affected by CaCl_2, bile salts and lecithin. Then, the effect of mucus on the structural change of lipolysed microemulsions was studied. The results of SAXS and FRET indicated that the liquid crystalline phases disappeared, and more micelles were generated. In summary, we studied the structural change of microemulsions in simulated gastrointestinal conditions by SAXS and FRET, and successfully monitored the appearance and disappearance of the liquid crystalline phases and micelles. | Xia Lv Shuguang Zhang Huipeng Ma Peipei Dong Xiaodong Ma Ming Xu Yan Tian Zeyao Tang Jinyong Peng Haibo Chen Jianbin Zhang | 2018 | Acta Pharmaceutica Sinica B2018，8，4： | 2 |
| 10 | Calibration of Mars Energetic Particle Analyzer (MEPA)显示文摘The first Mars exploration mission of China(Tianwen-1)is scheduled to be launched in 2020;a charged particle telescope,the Mars Energetic Particle Analyzer(MEPA),is carried as one of the payloads on the orbiter.The MEPA is designed to measure solar energetic particles(SEPs)and galactic cosmic rays(GCRs)in the near-Mars space and in the transfer orbit from Earth to Mars.Before the launch,the MEPA was calibrated in ground experiments with radioactive sources,electronic pulses,and accelerator beams.The calibration parameters,such as energy conversion constants,threshold values for the triggers,and particle identification criteria,were determined and have been stored for onboard use.The validity of the calibration parameters has been verified with radioactive sources and beams.The calibration results indicate that the MEPA can measure charged particles reliably,as designed,and that it can satisfy the requirements of the Tianwen-1 mission. | ShuWen Tang Yi Wang HongYun Zhao Fang Fang Yi Qian YongJie Zhang HaiBo Yang CunHui Li Qiang Fu Jie Kong XiangYu Hu Hong Su ZhiYu Sun YuHong Yu BaoMing Zhang Yu Sun ZhiPeng Sun | 2020 | Earth and Planetary Physics2020，4，4： | 2 |
| 11 | Spatial distribution and reconstruction potential of Japanese anchovy(Engraulis japonicus) based on scale deposition records in recent anaerobic sediment of the Yellow Sea and East China Sea显示文摘Many studies have revealed that anchovy has exhibited large variability in population size on decadal timescales. However, such works concerning anchovy population are mainly based on short historical catch records. In order to understand the causes of variability in fish stocks(natural and/or anthropogenic) and calibrate the error between catches and standing stocks, it is essential to develop long-term time series of fish stocks from the time when human impacts are minimal or negligible. Well preserved fish scales from sediment record are regarded as useful indicators revealing the history of fish population dynamics over the last centuries. Anchovy scales was first analyzed over the Yellow Sea and East China Sea and the largest abundance was found in the central South Yellow Sea where is regarded as the largest overwintering ground for Japanese anchovy(Engraulis japonicas). Thus in the central South Yellow Sea, two cores covering the last 150 years were collected for estimating fish scale flux. The scale deposition rate(SDR) records show that the decadal scale SDRs were obviously coherent between cores with independent chronologies. The calibration of downcore SDRs to the standing stocks of anchovy further validated that SDR is a reliable proxy to reconstruct the long-term anchovy population dynamic in the central South Yellow Sea where anoxic conditions prevail in the sediment. When assembled with other productivity proxies, it would be expected that SDR could be associated with changes in oceanic productivity and may make a contribution to determine the forcing factors and elucidate the mechanism of the process in future. | HUANG Jiansheng SUN Yao JIA Haibo YANG Qian TANG Qisheng | 2014 | Acta Oceanologica Sinica2014，33，12： | 2 |
| 12 | CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration显示文摘RNA-targeting CRISPR system Cas13 offers an efficient approach for manipulating RNA transcripts in vitro.In this perspective,we provide a proof-of-concept demonstration that Cas13-mediated Vegfa knockdown in vivo could prevent the development of laser-induced CNV in mouse model of Age-related macular degeneration. | Changyang Zhou Xinde Hu Cheng Tang Wenjia Liu Shaoran Wang Yingsi Zhou Qimeng Zhao Qiyu Bo Linyu Shi Xiaodong Sun Haibo Zhou Hui Yang | 2020 | National Science Review2020，7，5： | 2 |
| 13 | A Chance Constrained Optimal Reserve Scheduling Approach for Economic Dispatch Considering Wind Penetration显示文摘The volatile wind power generation brings a full spectrum of problems to power system operation and management, ranging from transient system frequency fluctuation to steady state supply and demand balancing issue. In this paper, a novel wind integrated power system day-ahead economic dispatch model, with the consideration of generation and reserve cost is modelled and investigated. The proposed problem is first formulated as a chance constrained stochastic nonlinear programming(CCSNLP), and then transformed into a deterministic nonlinear programming(NLP). To tackle this NLP problem, a three-stage framework consists of particle swarm optimization(PSO), sequential quadratic programming(SQP) and Monte Carlo simulation(MCS) is proposed. The PSO is employed to heuristically search the line power flow limits, which are used by the SQP as constraints to solve the NLP problem. Then the solution from SQP is verified on benchmark system by using MCS. Finally, the verified results are feedback to the PSO as fitness value to update the particles. Simulation study on IEEE30-bus system with wind power penetration is carried out, and the results demonstrate that the proposed dispatch model could be effectively solved by the proposed three-stage approach. | Yufei Tang Chao Luo Jun Yang Haibo He | 2017 | IEEE/CAA Journal of Automatica Sinica2017，4，2： | 1 |
| 14 | Experimental studies on reduction of evaporation from plain reservoirs in drought areas by benzene board covering technology显示文摘 | Jiang Haibo Tang Kai He Xinlin | 2015 | Journal of Coastal Research2015，31，5： | 1 |
| 15 | UltraStar:A Lightweight Simulator of Ultra-Dense LEO Satellite Constellation Networking for 6G显示文摘The mega-constellation network has gained significant attention recently due to its great potential in providing ubiquitous and high-capacity connectivity in sixth-generation(6G)wireless communication systems.However,the high dynamics of network topology and large scale of mega-constellation pose new challenges to the constellation simulation and performance evaluation.In this paper,we introduce UltraStar,a lightweight network simulator,which aims to facilitate the complicated simulation for the emerging mega-constellation of unprecedented scale.Particularly,a systematic and extensible architecture is proposed,where the joint requirement for network simulation,quantitative evaluation,data statistics and visualization is fully considered.For characterizing the network,we make lightweight abstractions of physical entities and models,which contain basic representatives of networking nodes,structures and protocol stacks.Then,to consider the high dynamics of Walker constellations,we give a two-stage topology maintenance method for constellation initialization and orbit prediction.Further,based on the discrete event simulation(DES)theory,a new set of discrete events is specifically designed for basic network processes,so as to maintain network state changes over time.Finally,taking the first-generation Starlink of 11927 low earth orbit(LEO)satellites as an example,we use UltraStar to fully evaluate its network performance for different deployment stages,such as characteristics of constellation topology,performance of end-to-end service and effects of network-wide traffic interaction.The simulation results not only demonstrate its superior performance,but also verify the effectiveness of UltraStar. | Xiaoyu Liu Ting Ma Zhixuan Tang Xiaohan Qin Haibo Zhou Xuemin(Sherman)Shen | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，3： | 1 |
| 16 | Disruption of a novel regu- latory locus results in decreased Bdnf expression, obesity, and type 2 diabetes in mice显示文摘 | Haibo Sha Jingyue Xu Jing Tang | 2007 | Physiol Genomics2007，31，： | 1 |
| 17 | Enhancement of the immune responses to foot-and-mouth disease vaccination in mice by oral administration of a Novel polysaccharide from the roots of Radix Cyathulae of fi cinalis Kuan (RC) Cellular Immunology 显示文摘 | Haibo Feng Xiaogang Du Jing Tang | 2013 | 281(2) : 111-1212013，281，2： | 1 |
| 18 | Privacy- conscious location-based queries in mobile environments 显示文摘 | Xu Jianliang Tang Xueyan Hu Haibo | 2009 | IEEE Transactions on Parallel and Distributed Systems2009，21，3： | 1 |
| 19 | Energy-storage-based low-frequency oscillation damping control using particle swarm optimization and heuristic dynamic programming显示文摘 | SUI Xianchao TANG Yanfei HE Haibo | 2014 | IEEE Tran- sactions on Power Systems2014，29，5： | 1 |
| 20 | Longitudinal propagation of fracture surface in cylindrical metal shells under explosive loading 显示文摘 | Hu Haibo Tang Tiegang Hu Bayi | 2007 | AIP Conference Proceedings2007，955，1： | 1 |
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