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| 1 | Clinical characteristics, treatment and prognosis of patients with idiopathic dilated cardiomyopathy: a tertiary center experience显示文摘Background Contemporary heart failure medications have led to considerable improvement in the survival of patients with heart failure. However,limited evidence is available regarding the effect of those medications in patients with idiopathic dilated cardiomyopathy (IDCM),particularly in China. We sought to analyze the trends in clinical characteristics and the prescription rate of recommended therapies and its prognostic impact in patients with IDCM. Methods From 2009 to 2016,1441 consecutive patients (age: 55±14 years,68% men,LVEF: 33%± 12%) fulfilling World Health Organization criteria for IDCM were enrolled in the current retrospective cohort study. Temporal trends of baseline clinical characteristics,treatment and prognosis were analyzed,and potential influential factors were explored. Results Rates of patients receiving angiotensin-converting enzyme inhibitors/angiotensin II receptors blockers,β-blockers,aldosterone receptor antagonists and diuretics increased from 55%,45%,58%,51% in 2009 to 67%,69%,71%,64% in 2016,respectively (P < 0.05);whereas,the proportion of patients receiving digoxin decreased from 39% in 2009 to 28% in 2016 (P < 0.05). The overall proportion of patients with optimal guideline-directed medical therapy (GDMT) was 44.6%;however,that rate increased from 33% in 2009 to 41%,49% and 56% in 2012,2014 and 2016 respectively (P < 0.05). Patients with optimal GDMT had a better outcome than those without,but there was no temporal trend toward improvement in the overall long-term prognosis of IDCM patients with the years. There was a trend towards admission of patients with milder disease and toward increased admission to a cardiology ward with the years. Conclusions An improvement in prescription rates of guideline-recommended medications in IDCM patients was observed. However,it remains suboptimal,and there is still some room for improvement. The prognosis of patients with optimal GDMT was better than those without. Moreover,the following patient category also had an improved prognosis: patients with LVEF ≥ 40%,with device therapy,and those admitted to a cardiology ward. | Abdullah Hagar Xiao-Bo PU Shi-Jian CHEN Jageshwar-Prasad Shah Mao CHEN | 2019 | Journal of Geriatric Cardiology2019，16，4： | 4 |
| 2 | 柴油乳化液喷雾闪急沸腾与微爆现象的激光阴影试验研究(英文)显示文摘在常压定容室内,应用ND:YAG激光阴影法、高分辨率CCD照相机和粒径分析软件,对不同含水量的柴油乳化液雾油滴的闪急沸腾与微爆现象以及油滴粒径分布进行了试验测量与变参数对比分析,探讨了在130℃温度条件下,乳化油含水量对乳化油喷雾液滴闪急沸腾和微爆的影响,揭示了微爆效应在喷雾雾化和液滴碎化中的作用机理。试验结果表明,包覆于油中的水相颗粒受热闪急沸腾所形成的高压蒸气团冲破无水边界层是导致油滴发生微爆和进一步破碎分裂的首要原因;微爆现象随乳化油含水量的增高而趋强;喷雾索特平均直径(SMD)的细化率随乳化油含水量和喷雾贯穿距的增加而增大,且乳化油含水量对喷雾SMD细化率的影响程度也随喷雾贯穿距的增加更加显著。 | MEDHAT Elkelawy 张煜盛 Alm El-Din Hagar 余敬周 El Zahaby A M El Shenawy E A Khalil A | 2009 | 内燃机学报2009，27，4： | 3 |
| 3 | An experimental study of particle transport in a deviated wellbore显示文摘 | | 1995 | The Journal of Canadian Petroleum Technology1995，34，2： | 1 |
| 4 | Crisis, farming &community 显示文摘 | Hagar C Haythornthwaite C | 2005 | The Journal of Community Informatics2005，1，3： | 1 |
| 5 | Cytoplasmic LPS activates caspase-11:implications in TLR4-independent endotoxic shock显示文摘 | Hagar JA Powell DA Aachoui Y | 2013 | Science2013，341，6151： | 1 |
| 6 | In vivo and in vitro antioxidant activity of ghrelin: Attenuation of gastric ischemic injury in the rat 显示文摘 | E1 Eter E A1 Tuwailiri A Hagar H | 2007 | J Gastroenterol Hepatol2007，22，11： | 1 |
| 7 | Cysteinyl leukotriene receptor antagonism alleviates renal injury induced by ischemia-reperfusion in rats显示文摘 | Hagar HH Abd El Tawab R | 2012 | J Surg Res2012，178，1： | 1 |
| 8 | Discontinuous Galerkin methods for ordinary differential equations 显示文摘 | DELFOUR M TROCHU F HAGAR W | 1981 | Mathematics of Com- putation1981，36，154： | 1 |
| 9 | Microglia cyclooxygenase-2 activity in experimental gliomas:possible role in cerebral edema formation显示文摘 | BADIE B SCHARTNER J M HAGAR A R | 2003 | Clin Cancer Res2003，9，2： | 1 |
| 10 | Study of cardiac and hemo- dynamic changes with airway pressure release ventilation and pressure control ventilation in ehildren with acute respiratory dis- tress syndrome显示文摘 | Hamed H Hagar A Gaber R | 2012 | Eur Respir J2012，40，9： | 1 |
| 11 | Arginine therapy:a new treatment for pulmonary hypertension in sickle cell disease 显示文摘 | Morris C R Morris S M Jr Hagar W | 2003 | Am J Respir Crit Care Med2003，168，1： | 1 |
| 12 | Effects of cyclic compressive loading on chaondrogenesis of rabbit bonemarrow derived mesenchymal stem cells 显示文摘 | HUANG C Y HAGAR K L FROST L E | 2004 | Stem Cells2004，22，3： | 1 |
| 13 | Caspase- 11 protects against bacteria that escape the vacuole显示文摘 | Aachoui ~ Leaf I A Hagar J A | 2013 | Science2013，339，6122： | 1 |
| 14 | Group and home-based tai chi in elderly subjects with knee osteoarthritis:a randomized controlled trial显示文摘 | Brismée JM Paige RL Chyu MC Boatright JD Hagar JM McCaleb JA | | 0，，： | 1 |
| 15 | Nuclear factor-kappaB inhibition by pyrrolidinedithiocarbamate attenuates gastric ischemia-reperfusion injury in rats显示文摘 | El Eter E Hagar HH Al-Tuwaijiri A | 2005 | Can J Physiol Pharmaeol2005，83，6： | 1 |
| 16 | Evaluation of energy recovery of multiple skin facades-The approach of DIGITHON 显示文摘 | Miehele De Carli Hagar Elarga Angelo Zarrella | 2014 | Energy and Buildings2014，85，： | 1 |
| 17 | Taurine attenuates hypertension and renal dysfunction induced by cyclosporine A in rat显示文摘 | Hagar H H Etter E Arafa M | 2006 | Clin Experim Pharmaco Physiol2006，33，3： | 1 |
| 18 | Ginkgo bilo-ba attenuates mucosal damage in a rat model of ulcerative colitis显示文摘 | Mustafa A El-Medany A Hagar HH | 2006 | Pharrnaco Res2006，53，4： | 1 |
| 19 | Comparative evaluation of a new family of transformerless modular DC-DC converters for high power applications显示文摘 | HAGAR A A LEHN P W | 2014 | IEEE Trans on Power Delivery2014，29，44： | 1 |
| 20 | Taurine attenuates hypertension and renal dysfunction induced by cyclosporine A in rats显示文摘 | Hagar HH El Etter E Arafa M | 2006 | Clin Exp Pharmacol Physiol2006，33，3： | 1 |
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