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| 1 | Exercise and non-alcoholic fatty liver disease: A systematic review and meta-analysis显示文摘 | Shelley E. Keating Daniel A. Hackett Jacob George Nathan A. Johnson | 2012 | Journal of Hepatology2012,,1: | 4 |
| 2 | Regulatory issues for genetically modified animals显示文摘Precision genetics and breeding have the potential to meet the agricultural needs and goals of the world in the 21 st century.These needs include increasing the efficiency of production of animals and improving their products with minimal impact on the environment.The USA is the major innovator in genomic science and the acknowledged leader in formulating policies to regulate genetic applications in medicine and agriculture.However,governments worldwide have been exceedingly reluctant to support the introduction of genetically modified(GM)animals into agriculture.Regulatory policies have stagnated due to legal guidelines that could not anticipate the needs and solutions that are evident today.This must change if we are to maintain planetary integrity.I propose a new,market-based regulatory model for GM livestock that has both a strong scientific foundation and has worked for 10000 years.The model is similar to that for information technology in which specific algorithms drive computer and cell phone applications.Genome engineers write genetic algorithms that drive the traits in biological organisms.Accordingly,GM products should be viewed in terms of their use and public benefit rather than by limitations to the genetic programing coming from a few highly vocal groups.Genetic algorithms(Genapps)of the 21st century will include not only introduction of synthetic genes,but also complete natural and synthetic biochemical pathways to produce agricultural products that are maximally efficient,healthy to humans and animals,and sustainable in an era of changing climates while avoiding environmental degradation. | Perry Bradbury HACKETT | 2020 | Frontiers of Agricultural Science and Engineering2020,7,2: | 2 |
| 3 | Detection of genetic diversity in tea (Camellia sinensis) using RAPD markers显示文摘 | Wachira F N Waugh R Hackett C A | 1995 | Genome1995,38,2: | 2 |
| 4 | A prospective trial of volumetric intensity-modulated arc therapy vs conventional intensity modulated radiation therapy in advanced head and neck cancer显示文摘AIM: To prospectively compare volumetric intensitymodulated arc therapy(VMAT) and conventional intensity-modulated radiation therapy(IMRT) in coverage of planning target volumes and avoidance of multiple organs at risk(OARs) in patients undergoing definitive chemoradiotherapy for advanced(stage Ⅲ or Ⅳ)squamous cell cancer of the head and neck. METHODS: Computed tomography scans of 20 patients with advanced tumors of the larynx, naso-, oroand hypopharynx were prospectively planned using IMRT(7 field) and VMAT using two arcs. Calculated doses to planning target volume(PTV) and OAR were compared between IMRT and VMAT plans. Dose-volume histograms(DVH) were utilized to obtain calculated doses to PTV and OAR, including parotids, cochlea,spinal cord, brainstem, anterior tongue, pituitary and brachial plexus. DVH's for all structures were compared between IMRT and VMAT plans. In addition the planswere compared for dose conformity and homogeneity. The final treatment plan was chosen by the treating radiation oncologist. RESULTS: VMAT was chosen as the ultimate plan in 18 of 20 patients(90%) because the plans were thought to be otherwise clinically equivalent. The IMRT plan was chosen in 2 of 20 patients because the VMAT plan produced concentric irradiation of the cord which was not overcome even with an avoidance structure. For all patients, VMAT plans had a lower number of average monitor units on average(MU = 542.85) than IMRT plans(MU = 1612.58)(P < 0.001). Using the conformity index(CI), defined as the 95% isodose volume divided by the PTV, the IMRT plan was more conformal with a lower conformity index(CI = 1.61) than the VMAT plan(CI = 2.00)(P = 0.003). Dose homogeneity, as measured by average standard deviation of dose distribution over the PTV, was not different with VMAT(1.45 Gy) or IMRT(1.73 Gy)(P = 0.069). There were no differences in sparing organs at risk.CONCLUSION: In this prospective study, VMAT plans were chosen over IMRT 90% of the time. Compared to IMRT, VMAT plans used only one third of the MUs, had shorter treatment times, and similar sparing of OAR. Overall, VMAT provided similar dose homogeneity but less conformity in PTV irradiation compared to IMRT. This difference in conformity was not clinically significant. | Simon D Fung-Kee-Fung Rachel Hackett Lee Hales Graham Warren Anurag K Singh | 2012 | World Journal of Clinical Oncology2012,3,4: | 2 |
| 5 | Frequency, Management, and Predictors of Abnormal Mood After Stroke: The Auckland Regional Community Stroke (ARCOS) Study, 2002 to 2003显示文摘 | Maree L. Hackett Craig S. Anderson | 2006 | Stroke2006,,: | 2 |
| 6 | Detection of genetic diversity in tea(Camellia sinensis) using RAPD Markers显示文摘 | Wachira F N Waugh R Hackett C A | 1995 | Genome1995,38,: | 1 |
| 7 | Detection of genetic diversity in tea (Camellia sinensis) using RAPD Markers显示文摘 | Wachira F N Waugh R Hackett C A | 1995 | Genome1995,38,: | 1 |
| 8 | Molecular reconstruction of Sleeping Beauty, a Tcl-like transposon from fish, and its transposition in human cells 显示文摘 | Ivics Z Hackett P B Plasterk R H | 1997 | Cell1997,91,4: | 1 |
| 9 | Microwave energy in the founndry显示文摘 | Schroeder R E HacKett W S | 1971 | Br Foundryman1971,,8: | 1 |
| 10 | Leader-member Exchange as a Mediator of the Relationship Between Transformational Leadership and Followers' Performance and Organizational Citizenship Behavior 显示文摘 | Wang H Law KS Hackett R_D | 2005 | Academy of Management Journal2005,,3: | 1 |
| 11 | Enzyme-multiplied immunoassay digoxin assay compared with fluorescence polarization immunoassay and amerlex 125I-radioimmunoassay at two Australian centers显示文摘 | Saccoia NC Hackett LP Mortis RG | 1996 | Ther Drug Monit1996,18,6: | 1 |
| 12 | Detection of genetic diversity in tea (Camellia Sinensis) using RAPD markers显示文摘 | Wichita F N Waugh R Hackett C A | 1995 | Genome1995,38,: | 1 |
| 13 | Molecular reconstruction of Sleeping Beauty,a Tcl like transposon from fish,and itstransposition in human cells显示文摘 | Ivics Z Hackett PB Plasterk RH | 1997 | Cell1997,91,4: | 1 |
| 14 | Further assessment of Meyer and Allen'S(1991)three-component model of organizational commitment显示文摘 | HACKETT R D BYCIO P HAUSDORF P A | 1994 | Journal of Applied Psychology1994,,79: | 1 |
| 15 | Differential dihydroflavonol reductase transcription and anthocyanin pigmentation in the juvenile and mature phase of ivy (Hedera helix)显示文摘 | Murray J R Smith A G Hackett W P | 1994 | Plant a1994,19,4: | 1 |
| 16 | Oxidative damage in age-re|ated macular degeneration显示文摘 | Shen JK Dong A Hackett SF | 2007 | Histol Histopatho12007,22,: | 1 |
| 17 | High-altitude illness 显示文摘 | Hackett P H Roach R C | 2001 | New England Journal of Medicine2001,345,: | 1 |
| 18 | The single,ancient origin of chromist plastids显示文摘 | Yoon H S Hackett J D Pinto G | | 0,,: | 1 |
| 19 | Subdivisions of audito- ry cortex and ipsilateral cortical connections of the parabelt au- ditory cortex in macaque monkeys显示文摘 | Hackett TA Stepniewska I Kaas JH | 1998 | J Comp Neurol1998,394,: | 1 |
| 20 | Adenovirus- mediated delivery of an anti- v antigen monoclonal anti- body protects mice against a lethal yersinia pestis chal- lenge显示文摘 | Sofer- Podesta C Ang J Hackett NR | | Infect Immun0,77,: | 1 |