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| 1 | Paresthesias in dentistry 显示文摘 | Moore PA Haas DA | 2010 | Dent Clin North Am2010，54，4： | 1 |
| 2 | Mortality incidence in outpatient anesthesia for dentistry in Ontario 显示文摘 | Nkansah P Haas DA Saso MA | 1997 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod1997，83，6： | 1 |
| 3 | Complete pathologic re- sponse after preoperative chemotherapy for pcolorectal liver me- tastases: myth or reality显示文摘 | Adam R Wicherts Da de Haas R J | 2008 | J Clin Oncol2008，26，10： | 1 |
| 4 | Patients with initially unresectable colorectal liver metastases: is there a possibility of cure? 显示文摘 | Adam R Wicherts DA de Haas RJ | 2009 | J Clin Oneol2009，27，11： | 1 |
| 5 | R1 resectionby necessity for colorectal liver metastases : is it still acontraindication to surgery 显示文摘 | de Haas RJ Wicherts DA Flores E | 2008 | Ann Surg2008，248，： | 1 |
| 6 | Is hepatic resectionjustified after chemotherapy in patients with colorectal livermetastases and lymph node involvement 显示文摘 | Adam R de Haas RJ Wicherts DA | 2008 | J Clin Oncol2008，26，： | 1 |
| 7 | Repeat hepatectomyfor recurrent colorectal metastases显示文摘 | Wicherts DA de Haas RJ Salloum C | 2013 | Br J Surg2013，100，6： | 1 |
| 8 | Evaluation of poly(L-lactic acid) as material for intravascular polymeric stents显示文摘 | Agrawal CM Haas KF Leopold DA | 1992 | Biomaterials1992，13，： | 1 |
| 9 | Molecular targets and mechanisms of radiosensitization using DNA damage response pathways 显示文摘 | Raleigh DR Haas - Kogan DA | 2013 | Future Oncology2013，9，2： | 1 |
| 10 | Patients with initially unresectable colorectal liver metastases:is there a possibility of cure 显示文摘 | Adam R Wicherts DA de Haas ILl | 2009 | J Clin Oncol2009，27，11： | 1 |
| 11 | In vivo kinematics of the low contact stress rotating platform total knee显示文摘 | Haas BD Komistek RD Dennis DA | | 0，，2： | 1 |
| 12 | Comparison of articaine and prilocaine anesthesia by infiltration in maxillary and mandibular arches显示文摘 | Haas DA Harper DG Saso MA | 1990 | Anesth Prog1990，37，5： | 1 |
| 13 | Comparison of simulta- neous or delayed liver surgery for limited synchronous colorectal metastases显示文摘 | de Haas R J Adam R Wicherts DA | 2010 | Br J Surg2010，97，8： | 1 |
| 14 | Concomitant extrahepatic disease in patients with colorectal liver metastases:when is there a place for surgery显示文摘 | Adam R de Haas R J Wicherts DA | | Annals of Surgery0，，： | 1 |
| 15 | Fulllength transcriptome assembly from RNA-Seq datawithout a reference genome显示文摘 | Grabherr M G Haas B J Yassour M Levin J Z Thompson DA Amit I Adiconis X Fan L Raychowdhury R Zeng Q | 2011 | Nature Biotechnology2011，29，7： | 1 |
| 16 | Patients with initially unresectable colorectal liver metastases: is there a possibility of cure显示文摘 | Adam R Wicherts DA de Haas R J | 2009 | J Clin Oncol2009，27，11： | 1 |
| 17 | Long-term outcome in patients with adrenal metastases following resection of colorectal liver metastases显示文摘 | de Haas RJ Rahy Martin AC Wicherts DA | | 0，，08： | 1 |
| 18 | Comparison of articaine and prilocaine anesthetia by infiltration in maxillary and mandibular arches显示文摘 | Haas DA Harper DG Saso MA | 1990 | Anesth Prog1990，37，5： | 1 |
| 19 | Co-nanoencapsulated meloxicam and curcumin improves cognitive impairment induced by amyloid-beta through modulation of cyclooxygenase-2 in mice显示文摘Alzheimer’s disease is a progressive brain disorder and complex mechanisms are involved in the physiopathology of Alzheimer’s disease.However,there is data suggesting that inflammation plays a role in its development and progression.Indeed,some non-steroidal antiinflammatory drugs,such as meloxicam,which act by inhibiting cyclooxygenase-2 have been used as neuroprotective agents in different neurodegenerative disease models.The purpose of this study was to investigate the effects of co-nanoencapsulated curcumin and meloxicam in lipid core nanocapsules(LCN)on cognitive impairment induced by amyloid-beta peptide injection in mice.LCN were prepared by the nanoprecipitation method.Male Swiss mice received a single intracerebroventricular injection of amyloid-beta peptide aggregates(fragment 25–35,3 nmol/3μL)or vehicle and were subsequently treated with curcumin-loaded LCN(10 mg/kg)or meloxicam-loaded LCN(5 mg/kg)or meloxicam+curcumin-co-loaded LCN(5 and 10 mg/kg,respectively).Treatments were given on alternate days for 12 days(i.e.,six doses,once every 48 hours,by intragastric gavage).Our data showed that amyloid-beta peptide infusion caused long-term memory deficits in the inhibitory avoidance and object recognition tests in mice.In the inhibitory avoidance test,both meloxicam and curcumin formulations(oil or co-loaded LCN)improved amyloid-beta-induced memory impairment in mice.However,only meloxicam and curcumin-co-loaded LCN attenuated non-aversive memory impairment in the object recognition test.Moreover,the beneficial effects of meloxicam and curcuminco-loaded LCN could be explained by the anti-inflammatory properties of these drugs through cortical cyclooxygenase-2 downregulation.Our study suggests that the neuroprotective potential of meloxicam and curcumin co-nanoencapsulation is associated with cortical cyclooxygenase-2 modulation.This study was approved by the Committee on Care and Use of Experimental Animal Resources,the Federal University of Pampa,Brazil(approval No.02-2015)on April 16,2015. | Maria Eduarda Ziani Gutierrez Anne Suély Pinto Savall Edina da Luz Abreu Kelly Ayumi Nakama Renata Bem Dos Santos Marina Costa Monteiro Guedes Daiana SilvaÁvila Cristiane Luchese Sandra Elisa Haas Caroline Brandão Quines Simone Pinton | 2021 | Neural Regeneration Research2021，16，4： | 1 |
| 20 | Mortality incidence in outpatient anesthesia for dentistry in Ontario 显示文摘 | Nkansah P Haas DA Saso MA | 1997 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod1997，83，6： | 1 |
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