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| 1 | Power management unit chip design for automobile active-matrix organic light-emitting diode display module显示文摘A power management unit (PMU) chip supplying dual panel supply voltage, which has a low electro-magnetic interference (EMI) characteristic and is favorable for miniaturization, is designed. A two-phase charge pump circuit using external pumping capacitor increases its pumping current and works out the charge-loss problem by using bulk-potential biasing circuit. A low-power start-up circuit is also proposed to reduce the power consumption of the band-gap reference voltage generator. And the ring oscillator used in the ELVSS power circuit is designed with logic devices by supplying the logic power supply to reduce the layout area. The PMU chip is designed with MagnaChip’s 0.25 μm high-voltage process. The driving currents of ELVDD and ELVSS are more than 50 mA when a SPICE simulation is done. | KIM J H PARK J H KIM J H CAO T V LEE T Y BAN H J YANG K KIM H G HA P B KIM Y H | 2009 | Journal of Central South University2009，16，4： | 4 |
| 2 | 全球药物滥用的疾病负担:来自2010年全球疾病负担研究显示文摘背景:直到目前还没有研究者系统地估计过全球及区域性的苯丙胺类、大麻、可卡因和阿片类药物依赖的患病率及其造成的疾病负担。我们旨在用伤残损失寿命年(YLDs)、过早死亡损失寿命年(YLLs)和伤残调整寿命年(DALYs)来估计药物依赖的患病率和其造成的疾病负担。方法:采用贝叶斯Meta回归的方法(Dis Mod-MR)对药物依赖的流行病学研究及2010年全球疾病、伤害及危险因素负担研究(GBD 2010)进行了系统综述,估计人群水平的药物依赖患病率。GBD 2010通过代表性社区调查和基于互联网的调查计算出新的失能权重。我们把估计的药物依赖患病率和新的失能权重结合起来估算药物依赖导致的YLDs、YLLs、DALYs和其作为相关疾病危险因素时导致的YLDs、YLLs和DALYs。结果:2010年,药物依赖直接造成了2千万的DALYs(95%UI(不确定区间)1.3-2.54千万),占全球全因DALYs的0.8%(0.6%-1.0%)。世界范围内,相比于其他药物,越来越多的人依赖于阿片类和苯丙胺类药物。阿片类药物依赖直接造成的疾病负担最大(DALYs为920万,95%UI为710-1140万)。在某些地区,药物依赖导致的DALYs所占比例比其他地区高出20倍,收入越高的国家药物依赖造成的负担所占比例也越高。注射吸毒所致HIV感染造成210万的DALYs(95%UI 110-360万),所致HCV感染导致50.2万的DALYs(95%UI 28.6-89.1万)。苯丙胺类药物依赖所致自杀造成85.4万的DALYs(95%UI 29.1-179.1万),阿片类药物依赖所致自杀造成67.1万的DALYs(95%UI 32.9-173.0万),可卡因依赖所致自杀造成32.4万的DALYs(95%UI 10.9-68.2万)。药物依赖导致的疾病负担最高的国家(>650 DALYs/10万人)包括美国,英国,俄罗斯和澳大利亚。结论:药物滥用是造成全球疾病负担的一个重要因素。为减少人群水平的疾病负担,我们需采取有效的措施(比如给予阿片类药物依赖者替代治疗及针具交换等)降低阿片类药物依赖和注射吸毒导致的疾病负担。 | 王同瑜 Degenhardt L Whiteford HA Ferrari AJ Baxter AJ Charlson FJ Hall WD Freedman G Burstein R Johns Engell RE Flaxman A Murray CJ Vos T | 2015 | 中国药物依赖性杂志2015，24，6： | 3 |
| 3 | Multicenter evaluation of recurrence in endoscopic submucosal dissection and endoscopic mucosal resection in the colon:A Western perspective显示文摘BACKGROUND While colon endoscopic mucosal resection(EMR)is an effective technique,removal of larger polyps often requires piecemeal resection,which can increase recurrence rates.Endoscopic submucosal dissection(ESD)in the colon offers the ability for en bloc resection and is well-described in Asia,but there are limited studies comparing ESD vs EMR in the West.AIM To evaluate different techniques in endoscopic resection of large polyps in the colon and to identify factors for recurrence.METHODS The study is a retrospective comparison of ESD,EMR and knife-assisted endoscopic resection performed at Stanford University Medical Center and Veterans Affairs Palo Alto Health Care System between 2016 and 2020.Knife-assisted endoscopic resection was defined as use of electrosurgical knife to facilitate snare resection,such as for circumferential incision.Patients≥18 years of age undergoing colonoscopy with removal of polyp(s)≥20 mm were included.The primary outcome was recurrence on follow-up.RESULTS A total of 376 patients and 428 polyps were included.Mean polyp size was greatest in the ESD group(35.8 mm),followed by knife-assisted endoscopic resection(33.3 mm)and EMR(30.5 mm)(P<0.001).ESD achieved highest en bloc resection(90.4%)followed by knife-assisted endoscopic resection(31.1%)and EMR(20.2%)(P<0.001).A total of 287 polyps had follow-up(67.1%).On follow-up analysis,recurrence rate was lowest in knife-assisted endoscopic resection(0.0%)and ESD(1.3%)and highest in EMR(12.9%)(P=0.0017).En bloc polyp resection had significantly lower rate of recurrence(1.9%)compared to non-en bloc(12.0%,P=0.003).On multivariate analysis,ESD(in comparison to EMR)adjusted for polyp size was found to significantly reduce risk of recurrence[adjusted hazard ratio 0.06(95%CI:0.01-0.57,P=0.014)].CONCLUSION In our study,EMR had significantly higher recurrence compared to ESD and knife-assisted endoscopic resection.We found factors including resection by ESD,en bloc removal,and use of circumferential incision were associated with significantly decreased recurrence.While further studies are needed,we have demonstrated the efficacy of ESD in a Western population. | Mike T Wei Margaret J Zhou Andrew A Li Andrew Ofosu Joo Ha Hwang Shai Friedland | 2023 | World Journal of Gastrointestinal Endoscopy2023，15，6： | 2 |
| 4 | Nucleotide excision repair gene XPD polymorphisms and genetic predisposition to melanoma显示文摘 | Tomescu D Kavanagh G Ha T | 2001 | Carcinogenesis2001，22，3： | 1 |
| 5 | The psychological impact of orthognathic surgery:A 9-month follow-up显示文摘 | Kiyak HA West RA Hohl T | 1982 | Am J Orthod1982，81，5： | 1 |
| 6 | Cementless alumina-on-a- lumina total hip arthroplasty in patients younger than 50 years:a 5 year minimum follow-up study显示文摘 | HA Y C KOO K H JEONG S T | 2007 | J Arthroplasty2007，22，2： | 1 |
| 7 | Activation of Toll - like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/rcperfusion 显示文摘 | Hua F Ma J Ha T | 2007 | J Neuroimmunol2007，190，12： | 1 |
| 8 | The journal impact factor: Too much of an impact 显示文摘 | Ha T Tan S Soo K | 2006 | Ann Acad Med Singapore2006，35，12： | 1 |
| 9 | Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism显示文摘 | Ha T Hua F Liu X | 2008 | Cardiovasc Res2008，78，3： | 1 |
| 10 | Selected compounds derived from Moutan Cortex stimulated glucose uptake and glycogen synthesisvia AMPK activation in human HepG2 cells 显示文摘 | Ha D T Trung T N Hien T T | 2010 | J Ethnopharmacol2010，131，2： | 1 |
| 11 | MicroRNA-125b protects against myocardial ischaemia/reperfusion injury via targeting p53-mediated apoptotic signalling and TRAF6 显示文摘 | Wang X Ha T Zou J | 2014 | Cardiovascular research2014，102，3： | 1 |
| 12 | Spline-based feature curves from point-sampled geometry显示文摘 | DANIELS II J OCHOTTA T HA L | 2008 | The Visual Computer2008，24，6： | 1 |
| 13 | Exposure to persistent organochlorine pollutants associates with human sperm Y:X chromosome ratio显示文摘 | Rignell HA Jonsson B | 2005 | Hum Reprod2005，20，： | 1 |
| 14 | Caregiver styles of feeding and child acceptance of food in rural Vietnam显示文摘 | Ha PB Bentley ME Sripaipan T | 2002 | Food Nutr Bull2002，23，4： | 1 |
| 15 | Early activation of IKKI3 during in vivo myocardial ischemia 显示文摘 | Li C Kao R L Ha T | 2001 | Am J Physiol Heart Circ Physiol2001，280，3： | 1 |
| 16 | Modulating Toll - like receptor mediated signaling by ( 1 - 3 ) - beta - D - glucan rapidly induces cardiop mtection 显示文摘 | Li C Ha T Kelley J | 2004 | Cardiovasc Res2004，61，3： | 1 |
| 17 | Differential effects of antipsychotic and antidepressant drugs on neurogenic re- gions in rats显示文摘 | Nasrallah HA Hopkins T Pixley SK | 2010 | Brain Res2010，1354，： | 1 |
| 18 | Prospective of 3 - dimen-sional volume rendered computerized tomography and conventional renal arteriorgraphy for surgieal planning in patiets undergoing laparseopie do- nor nephreetomy显示文摘 | E1 Fettouch HA Herts BR Nimeh T el al | 2003 | Urology2003，170，1： | 1 |
| 19 | Regulatory mechanism for the stimulatory action of genistein on glucose uptake in vitro and in vivo 显示文摘 | Ha BG Nagaoka M Yonezawa T | 2012 | Nutr Biochem2012，23，： | 1 |
| 20 | Apoptosis and cel ular vitality:issues in osteoarthritic cartilage degradation显示文摘 | Aigner T Kim HA | | 0，，08： | 1 |
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