|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Differential secretome analysis reveals CST6 as a suppressor of breast cancer bone metastasis显示文摘骨头转移从疾病是乳癌的经常的复杂并发症和病态和死亡的一个普通原因。在转移期间,分泌蛋白质在在癌症房间和主人基质之间的相互作用起关键作用。为了描绘分泌蛋白质,那与乳癌骨头转移被联系,我们比较四个 MDA-MB-231 (MDA231 ) 衍生物房间的 secretomes 的没有标签的 proteomic 分析与骨头转移的改变的能力衬里的 preformed。128 蛋白质的一个总数被发现是一致地在骨头回归线癌症房间的调节媒介的 up-/down-regulated。改变的蛋白质的充实的分子的函数包括了受体绑定和 peptidase 抑制。通过乳癌房间的另外的 transcriptomic 分析,我们选择了 cystatin E/M (CST6 ) ,在骨头变形的房间下面调整的一个半胱氨酸朊酶禁止者,为进一步功能的研究。我们的结果证明 CST6 压制了乳癌房间的增长,殖民地形成,迁居和侵略。对癌症房间活动性的镇压功能被癌症执行导出房间的可溶的 CST6。更重要地,在癌症房间的 CST6 的宫外的表示在动物学习救了老鼠免于公开 osteolytic 转移和死亡,当时 CST6 击倒的显著地提高的癌症房间骨头转移和弄短的动物幸存。总的来说,我们的学习提供了乳癌骨头向性的全身的 secretome 分析并且作为乳癌 osteolytic 转移的真正的 suppressor 建立了分泌 CST6。 | Lei Jin Yan Zhang Hui Li Ling Yao Da Fu Xuebiao Yao Lisa X Xu Xiaofang Hu Guohong Hu | 2012 | Cell Research2012，22，9： | 15 |
| 2 | 缺血性脑卒中后的中期血压变异性与临床结局的关系显示文摘本研究旨在探讨急性脑卒中患者发病7d内的中期血压变异性(blood pressure variability,BPV)与预后的关系。方法:本研究纳入873例急性缺血性脑卒中患者。通过计算发病7d内的收缩压和舒张压的变异系数来评价中期BPV。 | Wang Y Wang J Meng P Liu N Ji N Zhang G Xu B Zhou X Sun Y Xu Y Hui R He M 陈云 叶鹏 | 2018 | 中华高血压杂志2018，26，5： | 2 |
| 3 | Refinery planning under uncertainty 显示文摘 | Li W K Hui C W Li P Li A X | 2004 | Industrial & Engineering Chemistry Research2004，43，21： | 1 |
| 4 | Measuring customer satisfaction of FM service in housing sector:A structural equation model approach显示文摘 | HUI E C M ZHENG X | | 0，，5： | 1 |
| 5 | Evaluating tree species diversity based on neighborhood relationships显示文摘 | HUI G Y ZHAO X H ZHAO Z H | 2011 | Forest Science2011，57，： | 1 |
| 6 | Endolysosome involvement in LDL cholesterol-induced Alzheimer's disease-like pathology in primary cultured neurons显示文摘 | Hui L Chen X Geiger JD | 2012 | Life Sci2012，91，： | 1 |
| 7 | A comprehensive mapping of HIV-1genotypes in various risk groups and regions across China based on a nationwide molecular epidemiologic survey显示文摘 | Xiang H Hui X Yuhua R | 2012 | PLoS One2012，7，47： | 1 |
| 8 | Ultrasound enhanced heterogeneous activation of peroxydisulfate by magnetite catalyst for the degradation of tetracycline in water显示文摘 | HOU L HUI Z XUE X | 2012 | Separation & Purification Technology2012，84，2： | 1 |
| 9 | The R0-type fuzzy logic metric space and an algorithm for solving fuzzy modus ponens显示文摘 | Wang G J Hui X J Song J S | | (to appear)0，，： | 1 |
| 10 | Proteomic analysis of strawberry leaves infected with Colletotrichum fragariae显示文摘 | Fang X P Chen W Y Xin Y Hengmu Z Chengqi Y Hong Y Hui L Wenfei X Shuzhen W Guizhen Z Hongbo L Liang J Huasheng M Songlin R | 2012 | Journal of proteomics2012，75，： | 1 |
| 11 | Towards real-time community detection in large networks 显示文摘 | Leung I X Hui P Lio P | 2009 | Physical Review E2009，79，06： | 1 |
| 12 | Novel Cued Search Strategy Based on Information Gain for Phased Array Radar显示文摘 | L Jian-bin H Wei-dong X Hui | 2008 | Journal of Systems Engineering and Electronics(1004-4132)2008，19，2： | 1 |
| 13 | Cooperation Evolution and Dynamics in Metal Population: Stage Quilitrium Hypothesis 显示文摘 | Hui C Zhang F Han X | 2005 | Ecol Model2005，184，： | 1 |
| 14 | Effective-Medium for Weakly Nonlinear Composites显示文摘 | Bergman D J Hui P M | 1988 | Phys Rev B1988，38，10： | 1 |
| 15 | Reproductive effects of prenatal exposure to nonylphenol on zebrafish (Danio rerio)显示文摘 | YANG F X XU Y HUI Y | 2006 | Comparative Biochemistry and Physiology C2006，142，12： | 1 |
| 16 | Breast cancer following augmentation mammaplasty with polyacrylamide hydrogel (PAAG) injection显示文摘 | CHENG N X LIU L G HUI L | 2009 | Aesthetic Plast Surg2009，33，4： | 1 |
| 17 | Synthesis and characterization of surfactant- stabilized Pt/C nanocatalysts for fuel cellapplications显示文摘 | Prabhuram J Wang X C Hui L | 2003 | J Phys Chem B2003，107，11： | 1 |
| 18 | Optimization of cultivationconditions for extracellular polysaccharide and mycelium biomassby Morchella esculenta As51620显示文摘 | Hui X Lan S Ya S | 2008 | Biochem Eng J2008，39，1： | 1 |
| 19 | Studies of the electro-chemical behavior of epinephrine at a homocysteine self-assembled electrode显示文摘 | Zhang H M Zhou X L Hui R T | 2002 | Talanta2002，56，： | 1 |
| 20 | Effects of microstructure on fatigue crack growth behavior of Ti-6Al-2Zr-1Mo-1V ELI alloy显示文摘 | Li S K Xiong B Q Hui S X | 2008 | Materials Characterization2008，59，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员