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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination显示文摘 | Kumar S Talis A L Howley P M | 1999 | J Biol Chem1999，274，18： | 1 |
| 3 | Association of human papillomavirus types 16 and 18 E6 protein with p53 显示文摘 | Werness B A Levine A J Howley P M | 1990 | Science1990，248，4951： | 1 |
| 4 | Transacti-vation of a bovine papilloma virus transcriptional regula-tory element by the E2 gene product显示文摘 | Spalholz B A Yang Y C Howley P M | 1985 | Cell1985，42，1： | 1 |
| 5 | Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines显示文摘 | Baker C C Phelps W C Lindgren V Braun M J Gonda M A Howley P M | 1987 | J Virol1987，61，： | 1 |
| 6 | Proteomic approaches to the study of papillomavirus-host interactions显示文摘 | WHITE E A HOWLEY P M | 2013 | Virology2013，435，1： | 1 |
| 7 | Association of human papillomavirus types 16 and 18 E6 proteins with p53 显示文摘 | Werness B A Levine A J Howley P M | 1990 | Science1990，248，4951： | 1 |
| 8 | Functional characterization of interferon regulatory factor 3a (IRF- 3a), an alternative splice isoform of IRF 3显示文摘 | Karpova A Y Ronco L V Howley P M | 2001 | Mol Cell Biol2001，21，： | 1 |
| 9 | A comparison of one-dimensional traveling waves in inverse and normal fluidized beds显示文摘 | HOWLEY M A GLASSER B J | 2005 | Physics D:Nonlinear Phenomena2005，201，： | 1 |
| 10 | A human herpesvirus 7 glycoprotein,U21,diverts major histocompatibility complex class I molecules to lysosmes显示文摘 | Hudson A W Howley P M Ploegh H L | 2001 | J Virol2001，75，12： | 1 |
| 11 | The role of E6AP in the regulation of p53 protein levels in human papillomavirus(HPV)-positive and HPV-negative cells显示文摘 | TALIS A L HUIBREGTSE J M HOWLEY P M | 1998 | J Biol Chem1998，273，11： | 1 |
| 12 | Association of human papillomavirus16 and 18 E6 protein with p53 显示文摘 | Werness B A Levine A J Howley P M | 1990 | Science1990，248，： | 1 |
| 13 | Perio-perative acupuncture and postoperative acupressurecan prevent postoperative vomiting following paedia-tric tonsillectomy or adenoidectomy:apragmatic ran-domised controlled trial显示文摘 | Liodden I Howley M Grimsgaard A S | 2011 | Acupunct Med2011，29，1： | 1 |
| 14 | Association of human papillomavirus type 16 and 18 E6 proteins with P53显示文摘 | WernessB A Levine A J Howley P M | 1990 | Science1990，248，： | 1 |
| 15 | Treatment of open apex teeth using two types of white mineral trioxide aggregate after initial dressing with calcium hydroxide in children显示文摘 | Moore A Howley M F O'Connell A C | 2011 | Dent Traumatol2011，27，3： | 1 |
| 16 | The papillomavirus E2 regulatory proteins显示文摘 | McBride A A Romanczuk H Howley P M | 1991 | J Biol Chem1991，266，18： | 1 |
| 17 | Functional characterization of interferon regulatory factor 3a (IRF-3a), an alternative splice isoform of IRF-3 显示文摘 | KARPOVA A Y RONCO L V HOWLEY P M | 2001 | Mol Cell Biol2001，21，13： | 1 |
| 18 | Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma celllines显示文摘 | Baker C C Phelps W C Lindgren V Braun MJ Gonda M A Howley P M | 1987 | J Virol1987，61，： | 1 |
| 19 | Association of human papillo- mavims type 16 and 18 E6 proteins with P53显示文摘 | WernessB A Levine A J Howley M | 1990 | Science1990，248，： | 1 |
| 20 | The papillomavirus E2 regulatory proteins显示文摘 | McBride A A Romanczuk H Howley P M | 1991 | J Biol Chem1991，266，18： | 1 |
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