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	题名	作者	年代	出处	被引量
1	COX-2 polymorphisms-765G→C and-1195A→G and colorectal cancer risk显示文摘AIM:To determine the possible modulating effect of the COX-2 polymorphisms,-765G→C and-1195A→G, on the risk of colorectal cancer(CRC)in a Dutch population. METHODS:This case-control study includes 326 patients with CRC and 369 age-and gender-matched controls.Genotypes of the COX-2 polymorphisms -765G→C and-1195A→G were determined by polymerase chain reaction-based restriction fragment length polymorphism.COX-2 genotypes and haplotypes were analyzed and odds ratios with 95%confi- dence intervals were estimated by logistic regression. RESULTS:The-765GG genotype was associated with an increased risk of developing CRC(OR,1.45; 95%CI,1.03-2.04).No significant difference was observed in the genotype distribution of the-1195A→ G polymorphism between patients and controls.The GG/AC haplotype was present significantly less often in patients than in controls(OR 0.44;95%CI,0.22-0.85). When the AC,AG and GG haplotypes were investigated separately,the AC haplotype showed a tendency to be less frequent in patients than in controls(OR(AG/AC)0.78; 95%CI,0.57-1.06). CONCLUSION:The-765GG genotype is associatedwith an increased risk of developing CRC and the GG/ AC haplotype seems to protect against CRC.These findings suggest a modulating role for the COX-2 polymorphisms-765G→C and-1195A→G in the development of CRC in a Dutch population.	Juliёt H Hoff Rene HM te Morsche Hennie MJ Roelofs Elise MJ van der Logt Fokko M Nagengast Wilbert HM Peters	2009	World Journal of Gastroenterology2009，15，36：	6
2	Analysis of chromosome 22markers in nine schizophrenia pedigrees 显示文摘	Coon H Holik J Hoff M	1994	Am J Med Genet1994，54，1：	1
3	Functional Genomics in Plants 显示文摘	BOUCHEZ D HOFF H	1998	Plant Physiology1998，118，：	1
4	The half-lives of uranium-234 and thorium-230显示文摘	Cheng H Edwards R L Hoff J A	2000	Chem Geol2000，169，：	1
5	Spherically symmetric solutions of the Navier-Stokes equations for compressible, isothermal flow with large discontinuous initial data 显示文摘	Hoff D Novotn:: A Petzeltov: H	1992	Indiana Univ Math J1992，41，：	1
6	Insecticidal crystal proteins of Bacillus thuringiensis显示文摘	HOFFE H WHITELEY H R	1989	Microbiol Mol Biol R1989，53，：	1
7	The use of mutants and transgenic plants to study nitrate assimilation 显示文摘	HOFF T TRUONG H N CABOCHE M	1994	Plant Cell Environ1994，17，5：	1
8	The water challenge: Joint Water Project显示文摘	Hoff H	2002	Global Change Newsletter2002，，：	1
9	Maximal strength-training effects on force-velocity and force-power relationships explain increases in aerobic performance in humans显示文摘	STERS H HELGERUD J HOFF J	2002	Eur J Appl Physiol2002，88，3：	1
10	Hydrophobic interaction in tannin-protein complexes显示文摘	Oh H I Hoff J E Armstrong G S	1980	J Agric Food Chem1980，28，：	1
11	Myofibroblasts in palatal wound healing:prospects for the reduetion of wound eontrae- tion after deft palate repair 显示文摘	Van BeurdeB H E Von Den Hoff JW Toren SMA R	2005	J Dent Res2005，84，10：	1
12	Changes in the Periodontal ligament after experimental tooth movementusing hi^i and low continuous forces in beagle dogs显示文摘	Van Bt^il M Maltha J Van den Hoff H KuijPers - Jagtman AM	2004	AngleOrthod2004，74，1：	1
13	Distributed generation an alternative to electric utility investments in system capacity显示文摘	Hoff T E Wenger H J Farmer B K	1996	Energy Policy1996，24，2：	1
14	The evolution of fluoropyrimidine therapy: From intravenous to oral 显示文摘	Hoff P M Cassidy J Schmoll H J	2001	Oncologist2001，4，：	1
15	CD25 regulatory T cells determine secondary but not primary remission in EAE : impact on long-term disease progression显示文摘	Gartner D Hoff H Gimsa U	2006	J Neuroimmunol2006，172，12：	1
16	Industrial aspects and literature survey: fleet composition and routing 显示文摘	HOFF A ANDERSSON H CHRISTIANSEN M	2010	Computers and Operations Research2010，37，12：	1
17	pH dependence of complex formation between condensed tannins and proteins显示文摘	OH H HOFF J	1990	Journal of Agricultural Food Science1990，53，2：	1
18	Sorafenib in combination with capecitabine: an oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer 显示文摘	Baselga J Segalla JG Roch6 H Del Giglio A Pinczowski H Ciruelos EM Filho SC G6mez P Van Eyll B Bermejo B Llombart A Garicochea B Durdn Md Hoff PM Espi6 M de Moraes AA Ribeiro RA Mathias C Gil Gil M Ojeda B Morales J Kwon Ro S Li S Costa F	2012	J Clin Oncol2012，30，13：	1
19	Hydrophobic interaction in tannin-protein complexes显示文摘	Oh H I Hoff J E Armstrong G S	1980	J Agric Food Chem1980，28，：	1
20	A multimodal laser Doppler and endosonographie distension device for studying meehanosensation and mueosal blood flow in the oesophagus 显示文摘	HOFF DA GREGERSEN H ODEGAARD S	2006	Neurogastroenterol Motil2006，18，：	1

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