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| 1 | Favorable lifestyle before diagnosis associated with lower risk of screen-detected advanced colorectal neoplasia显示文摘AIM: To investigate the association between adherence to health recommendations and detection of advanced colorectal neoplasia(ACN) in colorectal cancer(CRC) screening.METHODS: A total of 14832 women and men were invited to CRC screening, 6959 in the fecal immunochemical test arm and 7873 in the flexible sigmoidoscopy arm. These were also sent a self-reported lifestyle questionnaire to be completed prior to their first CRC screening. A lifestyle score was created to reflect current adherence to healthy behaviors in regard to smoking, body mass index, physical activity, alcohol consumption and food consumption, and ranged from zero(poorest) to six(best). Odds ratios(ORs) and 95%CIs were calculated using multivariable logistic regression to evaluate the association between the single lifestyle variables and the lifestyle score and the probability of detecting ACN.RESULTS: In all 6315 women and men completed the lifestyle questionnaire, 3323(53%) in the FIT arm and 2992(47%) in the FS arm. This was 89% of those who participated in screening. ACN was diagnosed in 311(5%) participants of which 25(8%) were diagnosed with CRC. For individuals with a lifestyle score of two, three, four, and five-six, the ORs(95%CI) for the probability of ACN detection were 0.82(0.45-1.16), 0.43(0.28-0.73), 0.41(0.23-0.64), and 0.41(0.22-0.73), respectively compared to individuals with a lifestyle score of zero-one. Of the single lifestyle factors, adherence to non-smoking and moderate alcohol intake were associated with a decreased probability of ACN detection compared to being a smoker or having a high alcohol intake 0.53(0.42-0.68) and 0.63(0.43-0.93) respectively.CONCLUSION: Adopted healthy behaviors were inversely associated with the probability of ACN detection. Lifestyle assessment might be useful for risk stratification in CRC screening. | Markus D Knudsen Thomas de Lange Edoardo Botteri Dung-Hong Nguyen Helge Evensen Chloé B Steen Geir Hoff Tomm Bernklev Anette Hjartaker Paula Berstad | 2016 | World Journal of Gastroenterology2016，22，27： | 3 |
| 2 | 5-Aminosalicy显示文摘 | Baan B Dihal AN Hoff E | 2012 | Gut2012，61，12： | 1 |
| 3 | Effect of intravenous anaesthetics on spontaneous and endotoxin-stimulated cytokine response in cultured human whole blood 显示文摘 | LERSEN B HOFF G WHILHELM W | 1998 | Anaesthesiology1998，89，： | 1 |
| 4 | Effect of intravenous anesthetics on spontaneous and endotoxin-stimulated cytokine response in cultured human whole blood显示文摘 | Larsen B Hoff G Wilhelm W | 1998 | Anethesiology1998，89，5： | 1 |
| 5 | Role of bone morphogenetic proteins in cardiac differentiation显示文摘 | Wijk B Moorman A Hoff M | | 0，，02： | 1 |
| 6 | A liquid-liquid extraction procedure followed by a low temperature purifi- cation step for the analysis of macrocyclic lactones in milk by liquid chromatography-tandem mass spectrometry and fluorescence detection显示文摘 | Sameness G Barreto F Hoff R B | 2011 | Anal Chim Acta2011，705，12： | 1 |
| 7 | Molecular cloning and immunological characterization of potential allergens from the mould Fusarium culmorum显示文摘 | HOFF M BALLMER-WEBER B K NIGGEMANN B | 2003 | Mol Immunol2003，39，15： | 1 |
| 8 | Dynamic imaging of emer-ging resistance during cancer therapy 显示文摘 | Lee K C Hall D E Hoff B A | 2006 | Cancer Res2006，66，9： | 1 |
| 9 | Biochemical interpretation of quantitative structure-activity relationships ( QSAR ) for biodegradation of N-Heterocycles: A complementary approach to predict biodegradability 显示文摘 | Philipp B Hoff M Germa F | 2007 | Environmental Science & Technology2007，41，4： | 1 |
| 10 | β-lactam antibiotics residues analysis in bovine milk by LC-ESIMS/MS:a simple and fast liquid-liquid extraction method显示文摘 | JANK L HOFF R B TAROUCO P C | 2012 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess2012，29，4： | 1 |
| 11 | Effect of intravenous anesthetics on spontaneousand endotoxin-stimulated cytokine response in cultured human wholeblood显示文摘 | Larsen B Hoff G Wihelm W | 1998 | Anesthesiology1998，89，： | 1 |
| 12 | Distributed generation an alternative to electric utility investments in system capacity显示文摘 | Hoff T E Wenger H J Farmer B K | 1996 | Energy Policy1996，24，2： | 1 |
| 13 | Epicardium and myocardium originate from a common cardiogenie precursor pool 显示文摘 | van Wijk B van den Hoff M | 2010 | Trends Cardiovasc Med2010，20，1： | 1 |
| 14 | Validation of the GerdQ questionnaire for the diagnosis of gastro-oesophageal reflux disease显示文摘 | Jonasson C Wernersson B Hoff DA | 2013 | Aliment Pharmaeol Ther2013，37，5： | 1 |
| 15 | AcFKH1,a novel member of the forkhead family,associates with the RFX transcription factor CPCR1 in the cephalosporin C-producing fungus Acremonium chrysogenum显示文摘 | Schmitt EK Hoff B Kück U | 2004 | Gene2004，342，2： | 1 |
| 16 | Structure,function and regulation of nitrate reductase in higher plants显示文摘 | Hoff T Stummann B M Henningsen K W | 1992 | Physiologia Plantarum1992，84，4： | 1 |
| 17 | Childhood pineoblastoma:experiences from the prospective multicenter trials HIT-SKK87,HIT-SKK92 and HIT91显示文摘 | Hinkes B G Von Hoff K V Deinlein F | 2007 | J Neurooncol2007，81，： | 1 |
| 18 | An efficient fungal RNA-silencing system usingthe DsRed reporter gene显示文摘 | Janus D Hoff B Hofmann E | 2007 | Appl Environ Mierobiol2007，73，3： | 1 |
| 19 | Sorafenib in combination with capecitabine: an oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer 显示文摘 | Baselga J Segalla JG Roch6 H Del Giglio A Pinczowski H Ciruelos EM Filho SC G6mez P Van Eyll B Bermejo B Llombart A Garicochea B Durdn Md Hoff PM Espi6 M de Moraes AA Ribeiro RA Mathias C Gil Gil M Ojeda B Morales J Kwon Ro S Li S Costa F | 2012 | J Clin Oncol2012，30，13： | 1 |
| 20 | Preva-lence of pituitary deficiency in pa-tients after aneurysmal subarachnoid hemorrhage显示文摘 | Hoff C Sailer B | 2004 | J Clin Endocrinol Metab2004，89，： | 1 |
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