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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Nuclear magnetic resonance studies of 5,7-dihydroxyflavonoids 显示文摘 | Shen C C Chang Y S Ho L K | 1993 | Phytochem1993，34，3： | 1 |
| 3 | The architecture of the atrioventricular conduction axis in dog compared to man 显示文摘 | Ho S Y Kilpatrick L Kanai T | 1995 | J Cardiovasc Electrophysiol1995，6，1： | 1 |
| 4 | Stability and bifurcation of a rigidrotor-magnetic bearing system equipped with a thrustmagnetic bearing显示文摘 | Ho Y S Liu H Yu L | 2001 | Proc Inst Mech Engrs Part J: Journalof Engineering Tribology2001，215，5： | 1 |
| 5 | An incremental method for studying the steady state performance of induction motors using time stepping finite Transactions on Magnetics, element model显示文摘 | S L Ho W N Fu | 1997 | IEEE1997，33，2： | 1 |
| 6 | The chemistry and biotransformation of tea constitu- ents 显示文摘 | Sang S M Joshua D L Ho C T | 2011 | Pharmacological Research2011，64，： | 1 |
| 7 | Antiviral effect of epigallocatechin gallate on enterovirus 71显示文摘 | Ho H Y Cheng M L Weng S F | | 0，，14： | 1 |
| 8 | Suppressive oligonucleotides protect against collagen-induced arthritis in mice 显示文摘 | Dong L ho S Ishii K J | 2004 | Arthritis Rheum2004，50，5： | 1 |
| 9 | Theaflavin-3,3'-digallat from black tea blocks the nitric oxide synthase by down-regulating the aetivation of NF- kappaB in macrophages 显示文摘 | Lin Y L Tsai S H Lin-Shiau S Y Ho C T Lin J K | 1999 | Eur J Pharmaeol1999，367，： | 1 |
| 10 | Tuning of PID controllers based on gain and phase margin specifications 显示文摘 | Ho W K Hang C C Cao L S | 1995 | Automatica1995，31，3： | 1 |
| 11 | A Particle Swarm Optimization Method with Enhanced Global Search Ability for Design Optimizations of Electromagnetic Devices显示文摘 | Ho S L Yang S Y Ni G Z | 2006 | IEEE Trans on Magnetics2006，42，4： | 1 |
| 12 | NKG2D Recruits Two Distinct Adapters to Trigger NK Cell Activation and Costimulation显示文摘 | Gilfillan S Ho E L Cella M | 2002 | Nat Immunol2002，3，12： | 1 |
| 13 | herative learning control with initial rectifying action for nonlinear continuous systems 显示文摘 | Li X D Ho J K L Chow T W S | 2009 | lET Proc Control Theory and Applications2009，3，1： | 1 |
| 14 | Psychometric properties of the Chinese version of the mini-mental adjustment to cancer (MINI-MAC) scale显示文摘 | Ho S M Y Kam Fung W Chan C L W | 2003 | Psycho Oncol2003，12，6： | 1 |
| 15 | Agrobacterium-mediated production of transgenic rice plants expressing a chimeric α-amylase promoter β-glucuronidase gene显示文摘 | CHAN M T CHANG H H HO S L | 1993 | Plant Mol Biol1993，22，： | 1 |
| 16 | Analysis of the M/G/1 queue with n-policy and multiple vacations显示文摘 | Ho W L Soon S L | 1994 | Journal of Applied Probabality1994，31，： | 1 |
| 17 | Melt strength of linear lowdensity polyethylene/low-density polyethylene blends显示文摘 | Ho K Kale L Montgomery S | 2002 | Journal of Applied Polymer Science2002，85，： | 1 |
| 18 | Mango malformation disease in South China caused by Fus arium p roliferotum显示文摘 | ZHAN R L YANG S J HO H H LIU F ZHAO Y L CHANG J M HE Y B | 2010 | Journal of Phytopathology2010，158，： | 1 |
| 19 | Persistent genital human papillom avirus infection as a risk factor for persistent cervical dysplasia显示文摘 | Ho GY Burk RD Klein S et a l | 1995 | J Natl Cancer Inst1995，87，18： | 1 |
| 20 | Identification of linear time varying systems by Haar wavelet 显示文摘 | Chen S L Lai H C Ho K C | 2006 | Interna tional Journal of System Science2006，37，： | 1 |
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