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| 1 | 基于模糊逻辑的车辆侧偏角估计方法显示文摘提出了一种基于模糊逻辑的汽车侧偏角估计方法。它利用模糊逻辑和汽车运动学模型,将汽车转向盘转角、车轮转速、汽车加速度和横摆角速度信息相融合,进行车辆侧偏角估计。试验结果显示,该方法的鲁棒性和精确性较好,而且响应频率较高,可以满足ESP的控制需要。 | 施树明 Henk Lupker Paul Bremmer Joost Zuurbier | 2005 | 汽车工程2005，27，4： | 29 |
| 2 | Application of the Conditional Nonlinear Optimal Perturbation Method to the Predictability Study of the Kuroshio Large Meander显示文摘A reduced-gravity barotropic shallow-water model was used to simulate the Kuroshio path variations.The results show that the model was able to capture the essential features of these path variations.We used one simulation of the model as the reference state and investigated the effects of errors in model parameters on the prediction of the transition to the Kuroshio large meander (KLM) state using the conditional nonlinear optimal parameter perturbation (CNOP-P) method.Because of their relatively large uncertainties,three model parameters were considered:the interfacial friction coefficient,the wind-stress amplitude,and the lateral friction coefficient.We determined the CNOP-Ps optimized for each of these three parameters independently,and we optimized all three parameters simultaneously using the Spectral Projected Gradient 2 (SPG2) algorithm.Similarly,the impacts caused by errors in initial conditions were examined using the conditional nonlinear optimal initial perturbation (CNOP-I) method.Both the CNOP-I and CNOP-Ps can result in significant prediction errors of the KLM over a lead time of 240 days.But the prediction error caused by CNOP-I is greater than that caused by CNOP-P.The results of this study indicate not only that initial condition errors have greater effects on the prediction of the KLM than errors in model parameters but also that the latter cannot be ignored.Hence,to enhance the forecast skill of the KLM in this model,the initial conditions should first be improved,the model parameters should use the best possible estimates. | 王强 穆穆 Henk A.DIJKSTRA | 2012 | Advances in Atmospheric Sciences2012，29，1： | 25 |
| 3 | 外科-正畸联合矫治骨性下颌前突显示文摘为探讨正畸治疗和外科手术在矫治骨性下颌前突中的作用及相互关系,作者对159例患者的治疗计划及矫治结果进行分析,总结出正畸治疗在外科-正畸联合矫治下颌前突中的作用。主要包括:去除前牙代偿、排齐牙列、调整牙弓的相容性、调整关系、保持的稳定性,并强调去代偿是术前正畸治疗的主要目的。术前正畸治疗与后退下颌骨或(和)骨段的外科术式的选择之间有着密切关系,下颌体部截骨和升支部垂直截骨构成了经术前正畸准备后矫治下颌骨前突的主要外科术式。 | 琚泽程 徐宝华 Henk Tideman | 1996 | 中华口腔医学杂志1996，31，3： | 16 |
| 4 | 面向标准竞争优势的动态知识管理能力:形成机理与提升路径显示文摘[目的/意义]标准竞争优势的形成实质上是动态能力发挥作用的结果。从过程和内容视角构建基于资源和能力的整合框架,不仅是应对环境不确定性和复杂性的必然选择,也是改善组织绩效的现实要求。[方法/过程]在明晰关键知识构成要素的基础之上,阐述了动态知识管理能力的特征和影响因素。由“知识传导—动态能力—企业成长”的逻辑关系入手,从流程、位置和路径三个层面构建了动态知识管理能力的整合分析框架,揭示了动态知识管理能力的形成机理,并进一步归纳了其提升路径。[结果/结论]研究发现,标准知识宽度、标准知识深度与知识整合机制有效解释了动态知识管理能力的提升机理,动态知识管理能力的提升路径主要包括基础层、转化层和应用层,以此为企业获取技术标准竞争优势提供了理论依据。 | 吴玉浩 姜红 Henk de Vries | 2019 | 情报杂志2019，38，12： | 14 |
| 5 | h指数构建有创意 用于评价要慎重显示文摘Hirsch(美国加州大学物理系教授)提出的文献计量学指标,即h指数毫无疑问是最富有创意的。h指数已经引起了广泛的关注。通过Web of Science数据库(由汤姆森公司开发)可以收集到论文作者的所有文章及这些文章的被引次数。将这些论文按照其引文数降序排列,然后从排序最高的论文开始向下逐条计数,一直到某篇论文的排序号与该篇论文的引文数大敛相当为止,则该篇论文的序号数就是h指数数值。 | Henk F. Moed 刘俊婉(翻译) 金碧辉(审校) | 2006 | 科学观察2006，1，1： | 11 |
| 6 | Near-infrared fluorescence sentinel lymph node detection in gastric cancer: A pilot study显示文摘AIM: To investigate feasibility and accuracy of nearinfrared fluorescence imaging using indocyanine green: nanocolloid for sentinel lymph node(SLN) detection in gastric cancer.METHODS: A prospective, single-institution, phaseI feasibility trial was conducted. Patients suffering from gastric cancer and planned for gastrectomy were included. During surgery, a subserosal injection of 1.6 m L ICG:Nanocoll was administered around the tumor. NIR fluorescence imaging of the abdominal cavity was performed using the Mini-FLARE? NIR fluorescence imaging system. Lymphatic pathways and SLNs were visualized. Of every detected SLN, the corresponding lymph node station, signal-to-background ratio and histopathological diagnosis was determined. Patients underwent standard-of-care gastrectomy. Detected SLNs outside the standard dissection planes were also resected and evaluated.RESULTS: Twenty-six patients were enrolled. Four patients were excluded because distant metastases were found during surgery or due to technical failure of the injection. In 21 of the remaining 22 patients, at least 1 SLN was detected by NIR Fluorescence imaging(mean 3.1 SLNs; range 1-6). In 8 of the 21 patients, tumor-positive LNs were found. Overall accuracy of the technique was 90%(70%-99%; 95%CI), which decreased by higher p T-stage(100%, 100%, 100%, 90%, 0% for respectively Tx, T1, T2, T3, T4 tumors). All NIR-negative SLNs were completely effaced by tumor. Mean fluorescence signal-to-background ratio of SLNs was 4.4(range 1.4-19.8). In 8 of the 21 patients, SLNs outside the standard resection plane were identified, that contained malignant cells in 2 patients.CONCLUSION: This study shows successful use of ICG:Nanocoll as lymphatic tracer for SLN detection in gastric cancer. Moreover, tumor-containing LNs outside the standard dissection planes were identified. | Quirijn RJG Tummers Leonora SF Boogerd Wobbe O de Steur Floris PR Verbeek Martin C Boonstra Henricus JM Handgraaf John V Frangioni Cornelis JH van de Velde Henk H Hartgrink Alexander L Vahrmeijer | 2016 | World Journal of Gastroenterology2016，22，13： | 9 |
| 7 | Mechanical thrombectomy in patients with M1 occlusion and NIHSS score≤5:a single-centre experience显示文摘Background:The recent success of several mechanical thrombectomy trials has resulted in a significant change in management for patients presenting with stroke.However,it is still unclear how to manage patients that present with stroke and low National Institutes of Health Stroke Scale(NIHSS)≤5.We sought to review our experience of mechanical thrombectomy in patients with low NIHSS and confirmed M1 occlusion.Methods:We retrospectively analysed our prospectively maintained database of all patients undergoing mechanical thrombectomy between January 2008 and August 2016.We identified 41 patients with confirmed M1 occlusion and low NIHSS(≤5)on admission to our hospital.We collected demographic,radiological,procedural and outcome data.Results:The mean age of patients was 72±14,with 20 male patients.Associated medical conditions were common with hypertension seen in∼80%.Just over 50%presented with NIHSS 4 or 5.The average ASPECTS score on admission was 8.8(range 6–10),and the average clot length 10 mm.Angiographically Thrombolysis in Cerebral Infarction(TICI)≥2b was obtained in 87.8%of patients.7 patients had haemorrhage on follow-up,2 of which were symptomatic.Of 40 patients with 90-day follow-up,75%had modified Rankin Scale(mRS)score 0–2.There were 3 deaths at 90 days.Conclusions:Mechanical thrombectomy in patients with low NIHSS and proximal large vessel occlusion is technically possible and carries a high degree of success with good safety profile.Patients with low NIHSS and confirmed occlusion should be considered for mechanical thrombectomy. | P Bhogal P Bucke O Ganslandt H Bazner H Henkes M Aguilar Perez | 2016 | Stroke & Vascular Neurology2016，1，4： | 9 |
| 8 | 羧甲基木薯淀粉的取代方式研究显示文摘采用高效液相色谱(HPLC)和核磁共振波谱(1HNMR)分析了混水/有机介质中合成羧甲基木薯淀 粉的取代方式。发现HPLC是一种测定不同条件下合成的羧甲基木薯淀粉取代度(DS)的可靠方法。在测量 的范围内,未取代、一取代、二取代和三取代无水葡萄糖单元的摩尔分数分布和Spurlin模型非常吻合。用高 分辨率500MHz1HNMR分析了木薯淀粉羧甲基过程的取代度和反应顺序。依据淀粉和羧甲基淀粉(CMS) 的结构确定了各个峰位置。比较所得数据发现:依据HPLC计算的DSHPLC小于从500MHz1HNMR计算所得 的DS。无水葡萄糖单元中C2、C3和C6的羧甲基化反应顺序为C6>C2>C3。 | 姚杰 尤宏 包正 沈晋 Klaassien J Ganzeveld Jan Henk Marsman Hero J Heeres 陈文仁 | 2005 | 分析化学2005，33，2： | 8 |
| 9 | Cavernous hemangioma of adult pancreas: A case report and literature review显示文摘Pancreatic hemangioma is a rare type of benign vascular tumor.Low clinical suspicion and inability of current cross sectional imaging techniques to differentiate it from other pancreatic lesions,contribute to the difficulty in making the correct diagnosis.Without a definitive diagnosis,and due to concern for malignancy,in many instances,surgery is performed.We report a case of pancreas cavernous hemangioma in an 18-yearold female.The patient presented with three-month history of epigastric pain.Physical examination and routine blood tests were normal.Abdominal Computed Tomography scan revealed a 5 cm × 6 cm complex nonenhancing cystic mass in the head of pancreas.Magnetic resonance imaging,endoscopic ultrasonography(EUS) and EUS guided fine needle aspiration cytology were non-diagnostic.Because of uncontrolled symptoms,the patient underwent surgical resection.Histopathology and Immunohistochemical staining confirmed the diagnosis of cavernous hemangioma of pancreas. | Utpal Mondal Nichole Henkes David Henkes Laura Rosenkranz | 2015 | World Journal of Gastroenterology2015，21，33： | 7 |
| 10 | Subcutaneous cervical emphysema and pneumomediastinum due to a lower gastrointestinal tract perforation显示文摘This case report describes a 69-year-old man presen-ting with an extensive subcutaneous emphysema in his neck and generalized peritonitis caused by a lower gastrointestinal tract perforation. This case emphasizes that subcutaneous emphysema patients with negative thoracic findings should be scrutinized for signs of retroperitoneal hollow viscus perforation. | Georg B Schmidt Maarten W Bronkhorst Henk H Hartgrink Lee H Bouwman | 2008 | World Journal of Gastroenterology2008，14，24： | 6 |
| 11 | Amylopectin structure and crystallinity explains variation in digestion kinetics of starches across botanic sources in an in vitro pig model显示文摘Background: Starch is the main source of energy in commonly used pig diets.Besides effects related to the extent of starch digestion,also several effects related to variation in digestion rate have recently been demonstrated in non-ruminants.Different rates of starch digestion in animals and in in vitro models have been reported,depending on the botanic origin of starch.Starches from different botanic sources differ widely in structural and molecular properties.Predicting the effect of starch properties on in vitro digestion kinetics based on existing literature is hampered by incomplete characterization of the starches,or by a selective choice of starches from a limited number of botanic sources.This research aimed to analyse the relationships between starch properties and in vitro digestion kinetics of pure starches isolated from a broad range of botanic origins,which are used in non-ruminant diets or have a potential to be used in the future.Therefore we studied starch digestion kinetics of potato,pea,corn,rice,barley,and wheat starches,and analysed the granule diameter,number of pores,type and amount of crystalline structure,amylose content and amylopectin side-chain length of all starches.Results: Multivariate analysis revealed strong correlations among starch properties,leading us to conclude that effects of most starch characteristics are strongly interrelated.Across all analysed botanic sources,crystalline type and amylopectin chain length showed the strongest correlation with in vitro digestion kinetics.Increased percentages of A–type crystalline structure and amylopectin side chains of DP 6–24 both increased the rate of digestion.In addition,within,but not across,(clusters of) botanic sources,a decrease in amylose content and increase in number of pores correlated positively with digestion kinetics.Conclusion: The type of crystalline structure and amylopectin chain length distribution of starch correlate significantly with digestion kinetics of starches across botanic sources in an in vitro pig model.Variation in digestion kinetics across botanic sources is not additively explained by other starch properties measured,but appears to be confined within botanical sources. | Bianca M.J.Martens Walter J.J.Gerrits Erik M.A.M.Bruininx Henk A.Schols | 2019 | Journal of Animal Science and Biotechnology2019，10，1： | 6 |
| 12 | Induction of desiccation tolerance in desiccation sensitive Citrus limon seeds显示文摘Many economically important perennial species bear recalcitrant seeds, including tea, coffee, cocoa, mango,citrus, rubber, oil palm and coconut. Orthodox seeds can be dried almost completely without losing viability, but so-called recalcitrant seeds have a very limited storage life and die upon drying below a higher critical moisture content than orthodox seeds. As a result, the development of longterm storage methods for recalcitrant seeds is compromised.Lowering this critical moisture content would be very valuable since dry seed storage is the safest, most convenient and cheapest method for conserving plant genetic resources.Therefore, we have attempted to induce desiccation tolerance(DT) in the desiccation sensitive seeds of Citrus limon. We show that DT can be induced by paclobutrazol(an inhibitor of gibberellin biosynthesis) and we studied its associated transcriptome to delineate the molecular mechanisms underlying this induction of DT. Paclobutrazol not only interfered with gibberellin related gene expression but also caused extensive changes in expression of genes involved in the biosynthesis and signaling of other hormones. Paclobutrazol induced a transcriptomic switch encompassing suppression of biotic-and induction of abiotic responses.We hypothesize that this is the main driver of the induction of DT by paclobutrazol in C. limon seeds. | Alexandre Marques Harm Nijveen Charles Somi Wilco Ligterink Henk Hilhorst | 2019 | Journal of Integrative Plant Biology2019，61，5： | 5 |
| 13 | 标准化——多学科领域研究显示文摘本文通过一个系统的科学清单与标准化的特性相对照,指出了能够对标准化研究有贡献的学科,并且论证了标准化需要一个多学科的特殊方法来进行研究,其中管理学研究能够把其他学科的研究集成起来。 | Henk J.de Vries | 2011 | 中国标准化2011，，9： | 5 |
| 14 | 国产RPV钢铁离子辐照脆化行为的正电子湮灭研究显示文摘选取服役于我国高温气冷示范电站的反应堆压力容器(reactor pressure vessel,RPV)钢A508-3和纯Fe,采用3 Me V铁离子进行高温(250℃)与室温(约25℃)辐照,辐照损伤分别达0.1、0.5和1.0 dpa,对样品分别进行正电子湮灭和纳米压痕硬度研究。结果表明,辐照会使材料内部产生缺陷,这种缺陷以空位型缺陷和溶质原子团簇缺陷为主。且高温辐照产生的缺陷密度低于室温辐照,其中高温的退火效应使材料内部缺陷发生一定程度的回复。辐照后RPV钢和纯Fe都产生了一定程度的硬化,硬化程度随辐照损伤的增加而增高。对于RPV钢,高温辐照比室温辐照使材料内部产生更少的空位型缺陷和更多的溶质原子团簇型缺陷,因而RPV钢的辐照硬化可能主要是由溶质原子团簇型缺陷引起的。 | 张天慈 王海涛 李正操 SCHUT Henk 张征明 贺铭 孙玉良 | 2018 | 金属学报2018，54，4： | 5 |
| 15 | FSPM-P: towards a general functional-structural plant model for robust and comprehensive model development显示文摘在最后十年,功能结构的植物建模(FSPM ) 在庄稼和树生产成为了一个更广泛地接受的范例,当为最重要的庄稼的 3D 模型被建议了。给可得到的模型的更宽的公事包,在 FSPM 开发进入下一水平现在是适当的,由为模型开发介绍更有效的方法。这包括模型复用的考虑(由 modularisation ) ,联合和比较,和存在的改进当模特儿。便于这个过程,为设计的标准和要定义并且建立的通讯需要。我们在场第一步向一有效、一般,即,不是 speciesspecific FSPM,目前限制了为年度或每年两次的植物,但是与为扩展和进一步的归纳的潜力。模型结构是层次、面向对象的,与是的植物机关底级的目标和植物个人和华盖高度级的目标。,为生理的过程的多数的模块在有一个类似的目的另外的平台被合并(例如,光合作用,器官形成和生长) 。有从文学采用的几个一般参数集合的模拟跑证明能复制嘴巧的产量的现在的 prototypewas 为不同庄稼变化(油菜籽,大麦,等等)以动力学和最后的值(在收获时间)模型状态变量例如吸收生产,机关生物资源,叶区域和体系结构。 | Michael HENKE Winfried KURTH Gerhard H. BUCK-SORLIN | 2016 | Frontiers of Computer Science2016，10，6： | 5 |
| 16 | “国家环境与健康论坛”开幕式致词(节选)显示文摘经过政府多个部门协商,由卫生部、国家环保总局和世界卫生组织共同举办的“国家环境与健康论坛”于2005年11月18—19日在北京召开,有关部门的代表和各方面的专家围绕各自职能和专业就我国的环境与健康问题作了专题报告,并对我国“国家环境与健康行动计划(讨论稿)”进行了讨论。现将卫生部黄洁夫副部长、国家环保总局吴晓青副局长和世界卫生组织驻中国代表Dr.HenkBekedem在开幕式上的讲话(节选)刊出,以飨读者。 | 黄洁夫 吴晓青 Henk Bekedam | 2006 | 环境与健康杂志2006，23，1： | 4 |
| 17 | Emergency laparotomy in octogenarians: A 5-year study of morbidity and mortality显示文摘AIM: To determine the morbidity and mortality associated with emergency laparotomy for a clinically acute abdomen in patients aged ≥ 80 years. METHODS: In this retrospective audit, octogenarians undergoing emergency laparotomy between 1st January 2005 and 1 st January 2010 were identified using the Galaxy Theatre System. Patients undergoing abdominal surgery through groin crease incisions or Lanz or Gridiron incisions were excluded. Also simple appendectomies were excluded. All patients were aged 80 years or more at the time of their surgery. Data were obtained using casenote review with a standardised proforma to determine patient age, American Society of Anesthesiologists (ASA) grade, indications for surgery, early (within 30 d) and late (after 30 d) complications, mortality and length of stay. Data were inserted into a Microsoft Excel spreadsheet and analysed. RESULTS: One hundred patients were identified from the database (Galaxy) as having undergone emergency laparotomy. Of those, 55 underwent the procedure for intestinal procedures and 37 for secondary peritonitis.There was a 2:1 female predominance; average age 85 and ASA grade 3. Bowel resection was required in 51 out of the 100 patients and 22 (43%) died. Other procedures included appendicectomy, adhesiolysis, repair of AAA graft leak and colostomies for the pathological process resulting in an acute abdomen. Twelve of 100 patients (12%) suffered intra-operative complications, including splenic and bowel-serosal tears. Seventy patients (70%) had postoperative complications including myocardial infarction, wound infection, haematoma and sepsis. Overall mortality was 45/100 patients (45%). The major causes of death were sepsis (19/45 patients, 42%), underlying cancer (13/45 patients, 29%); with others including bowel obstruction (2/45 patients, 4%), myocardial and intestinal ischaemia and dementia. CONCLUSION: Emergency laparotomy in octogenarians carries a significant morbidity and mortality. In particular, surgery requiring bowel resection has higher mortality than without resection. | Gemma Green Irshad Shaikh Roland Fernandes Henk Wegstapel | 2013 | World Journal of Gastrointestinal Surgery2013，5，7： | 4 |
| 18 | Anemia and long-term outcome in adjuvant and neoadjuvant radiochemotherapy of stage Ⅱ and Ⅲ rectal adenocarcinoma:The Freiburg experience(1989-2002)显示文摘AIM:To evaluate the long-term outcome of standard5-FU based adjuvant or neoadjuvant radiochemotherapyand to identify the predictive factors,especially anemiabefore and after radiotherapy as well as hemoglobinincrease or decrease during radiotherapy.METHODS:Two hundred and eighty-six patientswith Union International Contre Cancer(UICC)stageⅡ and Ⅲ rectal adenocarcinomas,who underwentresection by conventional surgical techniques(lowanterior or abdominoperineal resection),receivedeither postoperative(n=233)or preoperative(n=53)radiochemotherapy from January 1989 until July 2002.Overall survival(OAS),cancer-specific survival(CSS),disease-free survival(DFS),local-relapse-free(LRS)and distant-relapse-free survival(DRS)were evaluatedusing Kaplan-Meier,Log-rank test and Cox's proportionalhazards as statistical methods.Multivariate analysis wasused to identify prognostic factors.Median follow-uptime was 8 years.RESULTS:Anemia before radiochemotherapy was anindependent prognostic factor for improved DFS(riskratio 0.76,P=0.04)as well as stage,grading,R status(free radial margins),type of surgery,carcinoembryonicantigen(CEA)levels,and gender.The univariate analysisrevealed that anemia was associated with impaired LRS (better local control)but with improved DFS.In contrast,hemoglobin decrease during radiotherapy was anindependent risk factor for DFS(risk ratio 1.97,P=0.04).During radiotherapy,only 30.8% of RO-resected patientssuffered from hemoglobin decrease compared to 55.6%if R1/2 resection was performed(P=0.04).The 5-yearOAS,CSS,DFS,LRS and DRS were 47.0%,60.0%,41.4%,67.2%,and 84.3%,respectively.Significantdifferences between preoperative and postoperativeradiochemotherapy were not found.CONCLUSION:Anemia before radiochemotherapyand hemoglobin decrease during radiotherapy have nopredictive value for the outcome of rectal cancer.Stage,grading,R status(free radial margins),type of surgery,CEA levels,and gender have predictive value for theoutcome of rectal cancer. | Christian Weissenberger Geissler Michael Otto Florian Barke Annette Henne Karl von Plehn Georg Rein Alex Müller Christine Bartelt Susanne Henke Michael | 2006 | World Journal of Gastroenterology2006，12，12： | 4 |
| 19 | Gastric cancer显示文摘 | Henk H Hartgrink Edwin PM Jansen Nicole CT van Grieken Cornelis JH van de Velde | 2009 | The Lancet . 2009 (9688)2009，，9688： | 4 |
| 20 | 8-Year Follow-up of Randomized Trial: Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy Versus Systemic Chemotherapy in Patients with Peritoneal Carcinomatosis of Colorectal Cancer显示文摘 | Vic J. Verwaal MD PhD Sjoerd Bruin MD Henk Boot MD PhD Gooike Slooten MD Harm Tinteren ScM | 2008 | Annals of Surgical Oncology2008，，9： | 3 |
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