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| 1 | Multivariate statistical analysis of clinicopathologic factors influencing survival of patients with bile duct carcinoma显示文摘AIM: To evaluate the influence of various clinicopathologicfactors on survival of patients with bile duct carcinoma aftercurative resection.METHODS: A retrospective analysis was made for 86 casesof bile duct carcinoma treated from January 1981 toSeptember 1995. Fifteen clinicopathologic factors possiblyinfluencing survival were selected. Independent variableswere first analyzed by univariate methods. Survival forvariable was estimated by the method of Kaplan and Meier.The variables that were statistically significant by univarlateanalysis were included in a multivariate analysis, which wereconfirmed using the Cox stepwise proportion hazard modelwith the help of SPSS 10.0 for Windows software.RESULTS: The overall cumulative survival rate was 72.6 %at 1 year, 32.4 % at 3 years, and 18.7 % at 5 years. Theresults of univariate analysis showed that the majorsignificant prognostic factors influencing survival of thesepatients were histological type of lesion, lymph nodemetastasis, pancreatic invasion, duodenal invasion, pedneuralinvasion, macroscopic vessel involvement, resected surgicalmargin and depth of cancer invasion (P=0.02, 0.02, 0.004,0.005, 0.01, 0.43, 0.03 and 0.04). Age, sex, location of tumor,size of tumor, macroscopic type of lesions, hepaticmetastasis, and hepatic invasion were not significantlyassociated with prognosis (P>0.05). Pancreatic invasion,perineural invasion and lymph node metastases were thethree most important prognostic factors by multivariateanalysis using the Cox proportional hazards model.CONCLUSION: Pancreatic invasion, pedneural invasion andlymph node metastases are the most important prognosticfactors for bile duct carcinoma after curative resection. | He, P Shi, JS Chen, WK Wang, ZR Ren, H Li, H | 2002 | World Journal of Gastroenterology2002,8,5: | 10 |
| 2 | Effects of radical cholecystectomy on nutritional and immune status in patients with gallbladder carcinoma显示文摘INTRODUCTION Carcinoma of the gallbladder is the most commonneoplasm in biliary tract,and its incidence has beenrising in recent years.The rate of correct diagnosisin early gallbladder carcinoma has been raised afterthe wide use of CT,ultrasound scans and frozensection examination.Now radical cholecystectomyis advocated as the best management for patientswith early gallbladder carcinoma.In the | Jiao XY Shi JS Wang JS Yang YJ He P | 2000 | World Journal of Gastroenterology2000,6,3: | 6 |
| 3 | Glyco-poly-L-lysine is better than liposomal delivery of exogenous genes to rat liver显示文摘AIM To compare the effects of liposomes andglyco-poly-L-lysine on liver targeted uptake andexpression of plasmid in rat liver.METHODS After binding with lipofectamine orgalactose-terminal glyco-poly-L-lysine,theplasmid could be expressed in eukaryotic cellswhen injected into Wistar rats by intravenousroute.At different time intervals after the injection,the distribution and expression of the plasmid inliver of rats were observed and compared using insitu hybridization and immunohistochemistry.RESULTS The expression of the plasmid bindingto liposomes or G-PLL could be markedly observed24 h later,and began to decrease one week later,but it still could be observed up to three weeks.Both liposomes and G-PLL could deliver theplasmid to the liver effectively,but the effect of thelatter was better than the former concerning thedistribution and expression of the plasmid targeteduptake in the liver.CONCLUSION G-PLL is better than liposome asthe targeted carrier for delivering exogenous genesto the liver. | Yang, CQ Wang, JY He, BM Liu, JJ Guo, JS | 2000 | World Journal of Gastroenterology2000,6,4: | 3 |
| 4 | Molecular diversity of microbial community in acid mine drainages of Yunfu sulfide mine显示文摘 | He ZG Xiao SM Xie XH Zhong H Hu YH Li QH Gao FL Li GY Liu JS Qiu GZ | 2007 | 中国生物学文摘2007,21,6: | 2 |
| 5 | High mobility group box I protein interacts with multiple Toll-like receptors 显示文摘 | Park JS Gamboni-Robertson F He Q | 2006 | Am J Physiol Cell Physiol2006,290,3: | 1 |
| 6 | Involvement of toll-like receptor 2 and 4 in cellular activation by high mobility group box 1 protein 显示文摘 | Park JS Svetkauskaite D He Q | 2004 | J Biol Chem2004,279,9: | 1 |
| 7 | Mitochondrial permeability transition: a common pathway to necrosis and apoptosis 显示文摘 | Kim JS He L Lemasters JJ | 2003 | Biochem Biophys Res Commun2003,304,3: | 1 |
| 8 | Atest of the generality of leaf trait relationships on the Tibetan Plateau 显示文摘 | HE JS WANGZ H WANGXP | 2006 | New Phytologist2006,170,4: | 1 |
| 9 | A LASSO-based approach to analyzing rare variants in genetic association studies 显示文摘 | Brennan JS He Y Calixte R | 2011 | BMC Proc2011,59,: | 1 |
| 10 | Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein显示文摘 | Park JS Svetkauskaite D He Q | 2004 | J Biol Chem2004,279,9: | 1 |
| 11 | A non-traumatic Staphylococcus aureus osteomyelitis model in pigs显示文摘 | Jensen HE Nielsen OL Agerholm JS | 2010 | In Vivo2010,24,3: | 1 |
| 12 | Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein显示文摘 | Park JS Svetkauskaite D He Q et 'al | 2004 | J Biol Chem2004,279,9: | 1 |
| 13 | Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein显示文摘 | Park JS Svetkauskaite D He Q | 2004 | J Biol Chem2004,279,9: | 1 |
| 14 | Mitochondrial permeability transition: a common pathway to necrosis and apoptosis显示文摘 | Kim JS He L Lemasters JJ | 2003 | Biochem Biophys Res Commun2003,304,3: | 1 |
| 15 | 查看详情显示文摘 | Lv RJ He JS Fu YH | | 0,,: | 1 |
| 16 | Saffloflavonesides A and B, two rearranged derivatives of flavonoid C-glycosides with a furan-tetrahydrofuran ring from Carthamu~ tinctorius 显示文摘 | He J Yang YN Jiang JS et 01 | 2014 | Org Lett2014,16,21: | 1 |
| 17 | A pharmacological,pharmacokinetic and clinical overview of risperidone,a new antipsychotic that blocks serotonin 5-HT2 and dopamine D2 receptors显示文摘 | Richardoson JS | 1995 | Int Clin Psychopharmacol1995,10,1: | 1 |
| 18 | High mobility group box 1 protein interacts with multiple Toll-like receptors显示文摘 | Park JS Gamboni RF He QB | 2006 | Am J Physiol Cell Physiol2006,290,3: | 1 |
| 19 | High mobility group box 1 protein interacts with multiple Toll-like receptors显示文摘 | Park JS Gamboni-Robertson F He Q | 2006 | Am J Physiol Cell Physiol2006,290,3: | 1 |
| 20 | A novel peptide probe for imagingand targeted delivery of liposomal doxorubicin to lung tumor显示文摘 | He X Na MH Kim JS | 2011 | Mol Pharm2011,8,2: | 1 |