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| 1 | Conventional, but not remote ischemic preconditioning, reduces iNOS transcription in liver ischemia/reperfusion显示文摘AIM:To study the effects of preconditioning on inducible nitric oxide synthase(iNOS)and interleukin 1(IL-1)receptor transcription in rat liver ischemia/reperfusion injury(IRI).METHODS:Seventy-two male rats were randomized into 3 groups:the one-hour segmental ischemia(IRI,n=24)group,the ischemic preconditioning(IPC,n=24)group or the remote ischemic preconditioning(RIPC,n=24)group.The IPC and R-IPC were performed as 10 min of ischemia and 10 min of reperfusion.The iNOS and the IL-1 receptor mRNA in the liver tissue was analyzed with real time PCR.The total Nitrite and Nitrate(NOx)in continuously sampled microdialysate(MD)from the liver was analyzed.In addition,the NOx levels in the serum were analyzed.RESULTS:After 4 h of reperfusion,the iNOS mRNA was significantly higher in the R-IPC(ΔCt:3.44±0.57)group than in the IPC(ΔCt:5.86±0.82)group(P=0.025).The IL-1 receptor transcription activity was reduced in the IPC group(ΔCt:1.88±0.53 to 4.81±0.21),but not in the R-IPC group,during reperfusion(P=0.027).In the MD,a significant drop in the NOx levels was noted in the R-IPC group(12.3±2.2 to 4.7±1.2μmol/L)at the end of ischemia compared with the levels in early ischemia(P=0.008).A similar trend was observed in the IPC group(11.8±2.1 to 6.4±1.5μmol/L),although this difference was not statistically significant.The levels of NOx rose quickly during reperfusion in both groups.CONCLUSION:IPC,but not R-IPC,reduces iNOS and IL-1 receptor transcription during early reperfusion,indicating a lower inflammatory reaction.NOx is consumed in the ischemic liver lobe. | Bergthor Bjornsson Anders Winbladh Linda Bojmar Tommy Sundqvist Per Gullstrand Per Sandstrom | 2014 | World Journal of Gastroenterology2014，20，28： | 5 |
| 2 | Induction of apoptosis in monocytes and lymphocytes by serum from patients with systemic lupus erythematosus - an additional mechanism to increased autoantigen load? 显示文摘 | Bengtsson AA Sturfelt G Gullstrand B | 2004 | Clin Exp Immunol2004，135，3： | 1 |
| 3 | Measurements of vertical displacement in running,a methodological comparison显示文摘 | Gullstrand L Halvorsen K Tinmark F | 2009 | Gait Posture2009，30，1： | 1 |
| 4 | Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease显示文摘 | Leffler J Martin M Gullstrand B | 2012 | J Immunology2012，188，： | 1 |
| 5 | Evaluation of splenic embolization monitored by the video dilution technique显示文摘 | Alwmark A Bengmark S Gullstrand P | 1982 | AnnSurg1982，198，： | 1 |
| 6 | Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus acti-vate complement exacerbating the disease显示文摘 | Leffler J Martin M Gullstrand B | 2012 | J Immunol2012，188，： | 1 |
| 7 | Remote or Conventional Ischemic Preconditioning –Local Liver Metabolism in Rats Studied with Microdialysis显示文摘 | Bergthor Bj?rnsson Anders Winbladh Linda Bojmar Lena M. Trulsson Hans Olsson Tommy Sundqvist Per Gullstrand Per Sandstr?m | 2012 | Journal of Surgical Research2012，，1： | 1 |
| 8 | Firm and destination - specific export costs: The case of the Swedish food sector 显示文摘 | Gullstrand J | 2011 | Food Policy2011，36，2： | 1 |
| 9 | Evaluation of splenic embolization in patients with hypertension and hypersplenism显示文摘 | Alwark A Bengmork S Gullstrand P | 1998 | Ann Surg1998，196，： | 1 |
| 10 | Complement clas- sical pathway components are all important in clearance of apoptotic and secondary necrotic ceils 显示文摘 | Gullstrand B Mgtrtensson U Sturfeh G | 2009 | Clin Exp Immunol2009，156，2： | 1 |
| 11 | IncreASed derum levels ofS100A8/A9 and S100A12 are associated with cardiov AScular dis-ease in patients with inactive systemic lupus erythmatosus显示文摘 | Tyden H Lood C Gullstrand B | 2013 | Rheumatology2013，52，： | 1 |
| 12 | Evaluation of Splenic Embolization in Patients with Portal Hypertension and Hypersplenism显示文摘 | ANDERS ALWMARK STIG BENGMARK PER GULLSTRAND B O JOELSSON ANDERS LUNDERQUIST TORBEN OWMAN | 1982 | Annals of Surgery1982，，： | 1 |
| 13 | Evaluation of splenic embolization in patients with portal hypertension and hypersplenism显示文摘 | Bengmark S Gullstrand P | 1982 | Ann Surg1982，196，5： | 1 |
| 14 | Characterization of non-expressed C4 genes in a case of complete C4 deficiency: identification of a novel point mutation leading to a premature stop codon显示文摘 | Fredrikson GN Gullstrand B Schneider PM | 1998 | Hum Immunol1998，59，11： | 1 |
| 15 | Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease显示文摘 | Leffler J Martin M Gullstrand B | 2012 | J Immunol2012，188，7： | 1 |
| 16 | Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease 显示文摘 | Leffler J Martin M Gullstrand B | 2012 | J Immunol2012，188，7： | 1 |
| 17 | Die dioptrit des angles In handbuch de physiologischeopitc 3 AuH edited by helmohotz H显示文摘 | Gullstrand A | 1990 | J Hanmburgl ceipzig1990，41，： | 1 |
| 18 | Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease显示文摘 | Leffler J Martin M Gullstrand B | 2012 | J Immunol2012，188，7： | 1 |
| 19 | Blood sampiing during continuous running and 30-second intervals on a treadmill:Effects on the lactate threshold results显示文摘 | GULLSTRAND L SJUDIN B SVEDENHAG J | 1994 | Scand J Sports Sci1994，4，4： | 1 |
| 20 | Increased serum levels of S100A8/ A9 and S100A12 are associated withcardiovascular disease in patients-with inactive systemic lupus erythematosus 显示文摘 | Tyden H Lood C Gullstrand B | 2013 | Rheumatology ( Oxford)2013，52，11： | 1 |
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