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| 1 | Effect of early enteral nutrition on postoperative nutritional status and immune function in elderly patients with esophageal cancer or cardiac cancer显示文摘Objective: To explore the effect of early enteral nutrition (EN) on postoperative nutritional status, intestinal permeability, and immune function in elderly patients with esophageal cancer or cardiac cancer. Methods: A total of 96 patients with esophageal cancer or cardiac cancer who underwent surgical treatment in our hospital from June 2007 to December 2010 were enrolled in this study. They were divided into EN group (n=50) and parenteral nutrition (PN) group (n=46) based on the nutrition support modes. The body weight, time to first flatus/defecation, average hospital stay, complications and mortality after the surgery as well as the liver function indicators were recorded and analyzed. Peripheral blood samples were collected on the days 1, 4 and 7 after surgery. The plasma diamine oxidase (DAO) activity and D-lactate level were determined to assess the intestinal permeability. The plasma endotoxin levels were determined using dynamic turbidimetric assay to assess the protective effect of EN on intestinal mucosal barrier. The postoperative blood levels of inflammatory cytokines and immunoglobulins were determined using enzyme- linked immunosorbent assay (ELISA). Results: After the surgery, the time to first flatus/defecation, average hospital stay, and complications were significantly less in the EN group than those in the PN group (P<0.05), whereas the EN group had significantly higher albumin levels than the PN group (P<0.05). On the 7th postoperative day, the DAO activity, D-lactate level and endotoxin contents were significantly lower in the EN group than those in the PN group (all P<0.05). In addition, the EN group had significantly higher IgA, IgG, IgM, and CD4 levels than the PN group (P<0.05) but significantly lower IL-2, IL-6, and TNF-α levels (P<0.05). Conclusions: In elderly patients with esophageal cancer or cardiac cancer, early EN after surgery can effectively improve the nutritional status, protect intestinal mucosal barrier (by reducing plasma endoxins), and enhance the immune | Guiping Yu Guoqiang Chen Bin Huang Wenlong Shao Guangqiao Zeng | 2013 | Chinese Journal of Cancer Research2013，25，3： | 67 |
| 2 | Review of nanofluids for heat transfer applications显示文摘Research on nanofluids has progressed rapidly since its enhanced thermal conductivity was first reported about a decade ago,though much controversy and inconsistency have been reported,and insufficient understanding of the formulation and mechanism of nanofluids further limits their applications.This work presents a critical review of research on heat transfer applications of nanofluids with the aim of identifying the limiting factors so as to push forward their further development. | Dongsheng Wen Guiping Lin Saeid Vafaei Kai Zhang | 2009 | Particuology2009，7，2： | 30 |
| 3 | Neuroprotective effects of rutaecarpine on cerebral ischemia reperfusion injury显示文摘Rutaecarpine,an active component of the traditional Chinese medicine Tetradium ruticarpum,has been shown to improve myocardial ischemia reperfusion injury.Because both cardiovascular and cerebrovascular diseases are forms of ischemic vascular disease,they are closely related.We hypothesized that rutaecarpine also has neuroprotective effects on cerebral ischemia reperfusion injury.A cerebral ischemia reperfusion model was established after 84,252 and 504 μg/kg rutaecarpine were given to mice via intraperitoneal injection,daily for 7 days.Results of the step through test,2,3,5-triphenyl tetrazolium chloride dyeing and oxidative stress indicators showed that rutaecarpine could improve learning and memory ability,neurological symptoms and reduce infarction volume and cerebral water content in mice with cerebral ischemia reperfusion injury.Rutaecarpine could significantly decrease the malondialdehyde content and increase the activities of superoxide dismutase and glutathione peroxidase in mouse brain.Therefore,rutaecarpine could improve neurological function following injury induced by cerebral ischemia reperfusion,and the mechanism of this improvement may be associated with oxidative stress.These results verify that rutaecarpine has neuroprotective effects on cerebral ischemia reperfusion in mice. | Chunlin Yan Ji Zhang Shu Wang Guiping Xue Yong Hou | 2013 | Neural Regeneration Research2013，8，22： | 20 |
| 4 | Experimental study of an aircraft fuel tank inerting system显示文摘In this work, a simulated aircraft fuel tank inerting system has been successfully established based on a model tank. Experiments were conducted to investigate the influences of different operating parameters on the inerting effectiveness of the system, including flow rate of the inert gas(nitrogen-enriched air), inert gas concentration, fuel load of the tank and different inerting approaches. The experimental results show that under the same operating conditions, the time span of a complete inerting process decreased as the flow rate of inert gas was increased; the time span using the inert gas with 5% oxygen concentration was much longer than that using pure nitrogen;when the fuel tank was inerted using the ullage washing approach, the time span increased as the fuel load was decreased; the ullage washing approach showed the best inerting performance when the time span of a complete inerting process was the evaluation criterion, but when the decrease of dissolved oxygen concentration in the fuel was also considered to characterize the inerting effectiveness, the approach of ullage washing and fuel scrubbing at the same time was the most effective. | Cai Yan Bu Xueqin Lin Guiping Sun Bing Zeng Yu Li Zixuan | 2015 | Chinese Journal of Aeronautics2015，28，2： | 15 |
| 5 | Macleaya cordata extract alleviated oxidative stress and altered innate immune response in mice challenged with enterotoxigenic Escherichia coli显示文摘This study examines the effects of dietary Macleaya cordata extract(MCE) on bacterial burden and resistance to enterotoxigenic Escherichia coli(ETEC) in ICR mice. ICR mice were randomly distributed into one of the following groups:(i) basal diet;(ii)basal diet with 200 mg kg–1 MCE;(iii) basal diet challenged with ETEC;and(iv) basal diet with 200 mg kg–1 MCE and challenged with ETEC. Following a 7-day period of pre-treatment, CTRL-ETEC and MCE-ETEC mice were subjected to oral infection using 5×108 E. coli SEC 470. The results showed dietary 200 mg kg–1 MCE markedly reduced intestinal ETEC burden(P<0.05) and the disease-associated mortality was significantly alleviated in the MCE treated group(P<0.05). In addition,dietary MCE markedly alleviated ETEC-induced oxidative stress, evidenced by the lowered methane dicarboxylic aldehyde(MDA) abundance and enhanced activities of catalase and glutathione peroxidase(P<0.05). Furthermore, MCE mice exhibited higher immune activity, which might have further mediated ETEC infection. These results indicate MCE plays a preventative role with respect to ETEC infection. Future research should aim to develop MCE as a therapeutic approach to the promotion of intestinal health and a safeguard against ETEC infection. | Guiping Guan Sujuan Ding Yulong Yin Veeramuthu Duraipandiyan Naif Abdullah Al-Dhabi Gang Liu | 2019 | Science China(Life Sciences)2019，62，8： | 12 |
| 6 | Experimental investigation on operating instability of a dual compensation chamber loop heat pipe显示文摘The operating instability of a dual compensation chamber loop heat pipe (DCC-LHP) including temperature hysteresis, reverse flow and temperature oscillation is described and explained in this paper. Test results indicate that the steady state operating temperature under the variable conductance mode is not the same during the power cycle tests with the same heat load, and it is lower during the power reduction cycle than that during the power increase cycle. Orientation has an effect on the heat load range when temperature hysteresis occurs, and the effect of power variation amplitude can be ignored. Reverse flow tends to occur in some of the startups at low heat loads, even if vapor existed in the vapor grooves initially, which is caused by a higher pressure inside the wick due to evaporation in the evaporator core or vapor penetration into it. Temperature oscillation tends to occur in some of the startups at low head loads or some steady-state operations at high heat loads. Especially when the compensation chamber with the bayonet through is above the evaporator, the incidence rate of temperature oscillation is high. | FENG JianTing LIN GuiPing BAI LiZhan | 2009 | Science China(Technological Sciences)2009，52，8： | 11 |
| 7 | FGF21 treatment ameliorates alcoholic fatty liver through activation of AMPK-SIRT1 pathway显示文摘成纤维细胞生长因素 21 (FGF21 ) , FGF 总科的一个最近识别的成员,主要从肝和脂肪质的纸巾被分泌并且在改进新陈代谢的症候群和动态平衡起一个重要作用。这研究的目的是在含酒精的脂肪肝疾病(AFLD ) 评估 FGF21 的角色并且决定它是否在 AFLD 上有治疗学的效果。在这份报纸,我们在长期的乙醇 gavage 和对待白酒的 HepG2 房间的一个鼠科的模型在导致白酒的肝损害上测试了 FGF21 的效果。男千米;公里老鼠每天收到了 5 g/kg 乙醇 gavage 的单个剂量 6 个星期,它导致了重要脂肪肝和肝损害。导致白酒的脂肪肝房间模型被在 75 公里的最后的集中增加乙醇进 HepG2 房间文化的媒介 9 天完成。结果与 recombinant FGF21 显示出那个处理在长期的乙醇 gavage 和对待白酒的 HepG2 房间的一个鼠科的模型的改善含酒精的脂肪肝和肝损害。另外, FGF21 处理下面调整丰满的酸的肝的表示合成的关键酶,激活的肝的 AMPK-SIRT1 小径和显著地下面调整的肝的氧化压力蛋白质。一起拿, FGF21 由 AMPK-SIRT1 小径的激活在 vitro 并且在 vivo 改正 AFLD 的多重新陈代谢的参数。 | Shenglong Zhu Lei Ma Yunzhou Wu Xianlong Ye Tianyuan Zhang Qingyang Zhang Lubna Muhi Rasoul Yunye Liu MO Guo Bing Zhou Guiping Ren Deshan Li | 2014 | Acta Biochimica et Biophysica Sinica2014，46，12： | 11 |
| 8 | Unruptured pregnancy in a noncommunicating rudimentary horn at37 weeks with a live fetus:a case report显示文摘We report an extremely rare case of an unruptured non-communicating rudimentary horn full-term pregnancy.A woman who had a uterine malformation was misdiagnosed as uterus didelphys and gave birth to a live,healthy fetus.The correct diagnosis was not made until cesarean section at 37 4/7 weeks.The case suggests that women who are pregnant in a rudimentary horn could obtain a full-term delivery and give birth to a live and healthy baby. | Chen Cheng Weiwei Tang Lei Zhang Mei Luo Meihua Huang Xiuling Wu Guiping Wan | 2015 | The Journal of Biomedical Research2015，29，1： | 11 |
| 9 | Spatial pattern of soil organic carbon in desert grasslands of the diluvial-alluvial plains of northern Qilian Mountains显示文摘The soil properties in arid ecosystems are important determinants of vegetation distribution patterns.Soil organic carbon(SOC)content,which is closely related to soil types and the holding capacities of soil water and nutrients,exhibits complex variability in arid desert grasslands;thus,it is essentially an impact factor for the distribution pattern of desert grasslands.In the present study,an investigation was conducted to estimate the spatial pattern of SOC content in desert grasslands and the association with environmental factors in the diluvial-alluvial plains of northern Qilian Mountains.The results showed that the mean values of SOC ranged from 2.76 to 5.80 g/kg in the soil profiles,and decreased with soil depths.The coefficients of variation(CV)of the SOC were high(ranging from 48.83%to 94.67%),which indicated a strong spatial variability.SOC in the desert grasslands of the study region presented a regular spatial distribution,which increased gradually from the northwest to the southeast.The SOC distribution had a pattern linked to elevation,which may be related to the gradient of climate conditions.Soil type and plant community significantly affected the SOC.The SOC had a significant positive relationship with soil moisture(P<0.05);whereas,it had a more significant negative relationship with the soil bulk density(BD)(P<0.01).However,a number of the variations in the SOC could be explained not by the environmental factors involved in this analysis,but rather other factors(such as grazing activity and landscape).The results provide important references for soil carbon storage estimation in this study region.In addition,the SOC association with environmental variables also provides a basis for a sustainable use of the limited grassland resources in the diluvial-alluvial plains of northern Qilian Mountains. | Rong YANG YongZhong SU Min WANG Tao WANG Xiao YANG GuiPing FAN TianChang WU | 2014 | Journal of Arid Land2014，6，2： | 11 |
| 10 | Research on Glutamate Synthase Activity in Sugar Beet(Beta Vulgaris L.)under Different Levels of Nitrogen显示文摘ResearchonGlutamateSynthaseActivityinSugarBeet(BetaVulgarisL.)underDifferentLevelsofNitrogenYanGuiping,MaFengming,LiWenhuaand... | Yan Guiping, Ma Fengming, Li Wenhua and Gao Jiguo (Northeast Agricultural University, Harbin 150030 PRC) | 1998 | Journal of Northeast Agricultural University(English Edition)1998，5，1： | 7 |
| 11 | The R2R3-MYB transcription factor GhMYB1a regulates flavonol and anthocyanin accumulation in Gerbera hybrida显示文摘Anthocyanins and flavonols have vital roles in flower coloration,plant development,and defense.Because anthocyanins and flavonols share the same subcellular localization and common biosynthetic substrates,these pathways may compete for substrates.However,the mechanism regulating this potential competition remains unclear.Here,we identified GhMYB1a,an R2R3-MYB transcription factor involved in the regulation of anthocyanin and flavonol accumulation in gerbera(Gerbera hybrida).GhMYB1a shares high sequence similarity with that of other characterized regulators of flavonol biosynthesis.In addition,GhMYB1a is also phylogenetically grouped with these proteins.The overexpression of GhMYB1a in gerbera and tobacco(Nicotiana tabacum)resulted in decreased anthocyanin accumulation and increased accumulation of flavonols by upregulating the structural genes involved in flavonol biosynthesis.We further found that GhMYB1a functions as a homodimer instead of interacting with basic helix-loop-helix cofactors.These results suggest that GhMYB1a is involved in regulating the anthocyanin and flavonol metabolic pathways through precise regulation of gene expression.The functional characterization of GhMYB1a provides insight into the biosynthesis and regulation of flavonols and anthocyanins. | Chunmei Zhong Yi Tang Bin Pang Xukun Li Yuping Yang Jing Deng Chengyong Feng Lingfei Li Guiping Ren Yaqin Wang Jianzong Peng Shulan Sun Shan Liang Xiaojing Wang | 2020 | Horticulture Research2020，7，1： | 7 |
| 12 | Flexible, Porous, and Metal–Heteroatom?Doped Carbon Nanofibers as Efficient ORR Electrocatalysts for Zn–Air Battery显示文摘Developing an e cient and durable oxygen reduction electrocatalyst is critical for clean-energy technology, such as fuel cells and metal–air batteries. In this study, we developed a facile strategy for the preparation of flexible, porous, and well-dispersed metal–heteroatom-doped carbon nanofibers by direct carbonization of electrospun Zn/Co-ZIFs/PAN nanofibers(Zn/Co-ZIFs/PAN). The obtained Zn/Co and N co-doped porous carbon nanofibers carbonized at 800 °C(Zn/Co–N@PCNFs-800) presented a good flexibility, a continuous porous structure, and a superior oxygen reduction reaction(ORR) catalytic activity to that of commercial 20 wt% Pt/C, in terms of its onset potential(0.98 V vs. RHE), half-wave potential(0.89 V vs. RHE), and limiting current density(-5.26 mA cm^(-2)). In addition, we tested the suitability and durability of Zn/Co–N@PCNFs-800 as the oxygen cathode for a rechargeable Zn–air battery. The prepared Zn–air batteries exhibited a higher power density(83.5 mW cm^(-2)), a higher specific capacity(640.3 mAh g^(-1)), an excellent reversibility, and a better cycling life than the commercial 20 wt% Pt/C + RuO_2 catalysts. This design strategy of flexible porous non-precious metal-doped ORR electrocatalysts obtained from electrospun ZIFs/polymer nanofibers could be extended to fabricate other novel, stable, and easy-to-use multi-functional electrocatalysts for clean-energy technology. | Qijian Niu Binling Chen Junxia Guo Jun Nie Xindong Guo Guiping Ma | 2019 | Nano-Micro Letters2019，11，1： | 7 |
| 13 | Preparation of multi-color quantum dots and its application to immunohistochemical analysis显示文摘Quantum dots (QDs) have the potential to be used in the multiplexed bioanalysis for their unique property:multi-color QDs can be excited at the same single wavelength light. In this work,high quan-tum yield multi-color core/shell QDs were prepared. After being water-solubilized by amphiphilic polymer based on self-assembling,the QDs would be labeled by two different IgGs and used in the multiplexed biodetection. Fluorescence resonance energy transfer (FRET) should be avoided in the multiplexed biodetection. In this work,spectral analysis showed that no FRET appeared in water-soluble QDs modified by amphiphilic polymer. The immunofluorescence in vitro indicated that the QDs-IgGs bioconjugates had excellent species-specific detection ability with nearly non-specific binding. The setting of this model will help to support the application of multi-color QDs in the multiplexed bioanalysis communities. | ZHANG BingBo LIU XuHui LI DeNa TIAN Hui MA GuiPing CHANG Jin | 2008 | Chinese Science Bulletin2008，53，13： | 6 |
| 14 | Using autologistic spatial models to simulate the distribution of land-use patterns in Zhangjiajie, Hunan Province显示文摘Nowadays,spatial simulation on land use patterns is one of the key contents of LUCC.Modeling is an important tool for simulating land use patterns due to its ability to inte-grate measurements of changes in land cover and the associated drivers.The conventional regression model can only analyze the correlation between land use types and driving factors, but cannot depict the spatial autocorrelation characteristics.Land uses in Yongding County, which is located in the typical karst mountain areas in northwestern Hunan province,were investigated by means of modeling the spatial autocorrelation of land use types with the purpose of deriving better spatial land use patterns on the basis of terrain characteristics and infrastructural conditions.Through incorporating components describing the spatial autocor-relation into a conventional logistic model,we constructed a regression model(Autologistic model),and used this model to simulate and analyze the spatial land use patterns in Yong- ding County.According to the comparison with the conventional logistic model without con- sidering the spatial autocorrelation,this model showed better goodness and higher accuracy of fitting.The distribution of arable land,wood land,built-up land and unused land yielded areas under the ROC curves(AUC)was improved to 0.893,0.940,0.907 and 0.863 respec- tively with the autologistic model.It is argued that the improved model based on autologistic method was reasonable to a certain extent.Meanwhile,these analysis results could provide valuable information for modeling future land use change scenarios with actual conditions of local and regional land use,and the probability maps of land use types obtained from this study could also support government decision-making on land use management for Yongding County and other similar areas. | WU Guiping ZENG Yongnian XIAO Pengfeng FENG Xuezhi HU Xiaotian | 2010 | Journal of Geographical Sciences2010，20，2： | 6 |
| 15 | Experimental study of curvature effects on jet impingement heat transfer on concave surfaces显示文摘Experimental study of the local and average heat transfer characteristics of a single round jet impinging on the concave surfaces was conducted in this work to gain in-depth knowledge of the curvature effects.The experiments were conducted by employing a piccolo tube with one single jet hole over a wide range of parameters:jet Reynolds number from 27000 to 130000,relative nozzle to surface distance from 3.3 to 30,and relative surface curvature from 0.005 to 0.030.Experimental results indicate that the surface curvature has opposite effects on heat transfer characteristics.On one hand,an increase of relative nozzle to surface distance(increasing jet diameter in fact)enhances the average heat transfer around the surface for the same curved surface.On the other hand,the average Nusselt number decreases as relative nozzle to surface distance increases for a fixed jet diameter.Finally,experimental data-based correlations of the average Nusselt number over the curved surface were obtained with consideration of surface curvature effect.This work contributes to a better understanding of the curvature effects on heat transfer of a round jet impingement on concave surfaces,which is of high importance to the design of the aircraft anti-icing system. | Zhou Ying Lin Guiping Bu Xueqin Bai Lizhan Wen Dongsheng | 2017 | Chinese Journal of Aeronautics2017，30，2： | 6 |
| 16 | Dicer-independent RNA-directed DNA methylation in Arabidopsis显示文摘指导 RNA 的 DNA methylation (RdDM ) 是在工厂的一条重要 de novo DNA methylation 小径。小介入 RNA (siRNAs ) 从 RNA 聚合酶 IV (Pol IV ) 由 Dicers 产生了抄本被认为指导顺序特定的 DNA methylation。到进 RdDM 的机制的获得卓见,我们执行了许多 Arabidopsis 异种定序的整个染色体的重亚硫酸盐,包括在 Pol IV (nrpd1 ) 或 Dicer (dcl1/2/3/4 ) 缺乏的工厂活动。出人意料地, RdDM 目标 loci,那要求了 Pol IV 或 Pol V,仅仅 16% 充分依赖于 Dicer 活动。DNA methylation 部分或完全独立于在留下的 Pol IV- 或 Pol 的 Dicer 活动 V 依赖的 loci,尽管有 24-nt siRNAs 的损失。相反, DNA methylation 层次至多与 Pol IV 依赖的 25-50 nt RNA 的累积相关在 Dicer 变异的植物的 loci。我们的结果建议在植物的 RdDM 被骰子无关的非编码的 RNA 的一个以前未得到欣赏的班大部分指导,并且那 siRNAs 被要求在仅仅 loci 的一个子集维持 DNA methylation。 | Dong Lei Yang Guiping KaiFang Jingwen Lan Yang HuanHuang HengZhung Jian Kang zhu | 2016 | Cell Research2016，26，1： | 5 |
| 17 | Experimental investigation and correlation development of jet impingement heat transfer with two rows of aligned jet holes on an internal surface of a wing leading edge显示文摘Extensive experimental studies on the heat transfer characteristics of two rows of aligned jet holes impinging on a concave surface in a wing leading edge were conducted, where50000 Rej 90000, 1.74 H/d 27.5, 66° a 90°, and 13.2 r/d 42.03. The finding was that the heat transfer performance at the jet-impingement stagnation point with two rows of aligned jet holes was the same as that with a single row of jet holes or the middle row of three-row configurations when the circumferential angle of the two jet holes was larger than 30°. The attenuation coefficient distribution of the jet impingement heat transfer in the chordwise direction was so complicated that two zones were divided for a better analysis. It indicated that: the attenuation coefficient curve in the jet impingement zone exhibited an approximate upside-down bell shape with double peaks and a single valley; the attenuation coefficient curve in the non-jet impingement zone was like a half-bell shape, which was similar to that with three rows of aligned jet holes; the factors,including Rej, H/d and r/d, affected the attenuation coefficient value at the valley significantly.When r/d was increased from 30.75 to 42.03, the attenuation rates of attenuation coefficient increased only by 1.8%. Consequently, experimental data-based correlation equations of the Nusselt number for the heat transfer at the jet-impingement stagnation point and the distributionof the attenuation coefficient in the chordwise direction were acquired, which play an important role in designing the wing leading edge anti-icing system with two rows of aligned jet holes. | Jia YU Long PENG Xueqin BU Xiaobin SHEN Guiping LIN Lizhan BAI | 2018 | Chinese Journal of Aeronautics2018，31，10： | 5 |
| 18 | Application of Constructed Wetlands on Wastewater Treatment for Aquaculture Ponds显示文摘A group of constructed wetlands (CWs) were applied to the recir-culating aquaculture system. This study assessed the performance of CWs in treating the aquaculture wastewater, examined the water quality condition of aquaculture ponds and the growth and the survival rate of 'target' species (Ictalurus punctatus and Megalobrama amblycephala). The results showed that CWs were effective on reducing the concentrations of 5-day biochemical oxygen demand (BOD5, at 70.5%), total suspended solids (TSS, at 81.9%), chlorophyll a (Chl-a, at 91.9%), ammonium (NH4+, at 61.5%) and nitrate nitro-gen (NO3--N, at 68.0%). Effect of CWs on phosphate (PO43--P) removal was relatively lower (at 20.0%). The concentrations of BOD5, TSS, Chl-a, NH4+ and TN, TP in the recirculating culture pond were significantly lower than that in the control pond( p0.05∧). CWs could help to increase total yield, survival rate of the 'target' species and significantly decrease feed conversion ratio ( p0.05∧). | LI Gu WU Zhenbin CHENG Shuiping LIANG Wei HE Feng FU Guiping ZHONG Fei | 2007 | Wuhan University Journal of Natural Sciences2007，12，6： | 5 |
| 19 | Overaccumulation of glycine betaine makes the function of the thylakoid membrane better in wheat under salt stress显示文摘Wheat(Triticum aestivum L.) lines T1, T4, and T6 were genetically modified to increase glycine betaine(GB) synthesis by introduction of the BADH(betaine aldehyde dehydrogenase, BADH)gene from mountain spinach(Atriplex hortensis L.). These transgenic lines and WT of wheat(T. aestivum L.) were used to study the effect of increased GB synthesis on wheat tolerance to salt stress. Salt stress due to 200 mmol L-1Na Cl impaired the photosynthesis of the four wheat lines, as indicated by declines in net photosynthetic rate(Pn), stomatal conductance(Gs),maximum photochemical efficiency of PSII(Fv/Fm), and actual photochemical efficiency of PSII(ФPSII) and an increase in intercellular CO2concentration(Ci). In comparison with WT, the effect of salinity on the three transgenic lines was mild. Salt stress caused disadvantageous changes in lipids and their fatty acid compositions in the thylakoid membrane of the transgenic lines and WT. Under salt stress, the three transgenic lines showed slightly higher chlorophyll and carotenoid contents and higher Hill reaction activities and Ca2+-ATPase activity than WT. All the results suggest that overaccumulation of GB resulting from introduction of the BADH gene can enhance the salt tolerance of transgenic plants, especially in the protection of the components and function of thylakoid membranes, thereby making photosynthesis better. Changes in lipids and fatty acid compositions in the thylakoid membrane may be involved in the increased salt stress tolerance of the transgenic lines. | Fengxia Tian Wenqiang Wang Chao Liang Xin Wang Guiping Wang Wei Wang | 2017 | The Crop Journal2017，5，1： | 4 |
| 20 | New insights into the associations among feed efficiency, metabolizable efficiency traits and related QTL regions in broiler chickens显示文摘Background: Improving the feed efficiency would increase profitability for producers while also reducing the environmental footprint of livestock production. This study was conducted to investigate the relationships among feed efficiency traits and metabolizable efficiency traits in 180 male broilers. Significant loci and genes affecting the metabolizable efficiency traits were explored with an imputation-based genome-wide association study. The traits measured or calculated comprised three growth traits, five feed efficiency related traits, and nine metabolizable efficiency traits.Results: The residual feed intake(RFI) showed moderate to high and positive phenotypic correlations with eight other traits measured, including average daily feed intake(ADFI), dry excreta weight(DEW), gross energy excretion(GEE), crude protein excretion(CPE), metabolizable dry matter(MDM), nitrogen corrected apparent metabolizable energy(AMEn), abdominal fat weight(Ab F), and percentage of abdominal fat(Ab P). Greater correlations were observed between growth traits and the feed conversion ratio(FCR) than RFI. In addition, the RFI, FCR, ADFI, DEW,GEE, CPE, MDM, AMEn, Ab F, and Ab P were lower in low-RFI birds than high-RFI birds(P < 0.01 or P < 0.05), whereas the coefficients of MDM and MCP of low-RFI birds were greater than those of high-RFI birds(P < 0.01). Five narrow QTLs for metabolizable efficiency traits were detected, including one 82.46-kb region for DEW and GEE on Gallus gallus chromosome(GGA) 26, one 120.13-kb region for MDM and AMEn on GGA1, one 691.25-kb region for the coefficients of MDM and AMEn on GGA5, one region for the coefficients of MDM and MCP on GGA2(103.45–103.53 Mb), and one 690.50-kb region for the coefficient of MCP on GGA14. Linkage disequilibrium(LD) analysis indicated that the five regions contained high LD blocks, as well as the genes chromosome 26 C6 orf106 homolog(C26 H6 orf106), LOC396098, SH3 and multiple ankyrin repeat domains 2(SHANK2), ETS homologous factor(EHF), and histamine receptor H3-like(HRH3 L), which are known to be involved in the regulation of neurodevelopment, cell proliferation and differentiation, and food intake.Conclusions: Selection for low RFI significantly decreased chicken feed intake, excreta output, and abdominal fat deposition, and increased nutrient digestibility without changing the weight gain. Five novel QTL regions involved in the control of metabolizable efficiency in chickens were identified. These results, combined through nutritional and genetic approaches, should facilitate novel insights into improving feed efficiency in poultry and other species. | Wei Li Ranran Liu Maiqing Zheng Furong Feng Dawei Liu Yuming Guo Guiping Zhao Jie Wen | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 4 |
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