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| 1 | Risk factors for colonic diverticular bleeding:A Westernized community based hospital study显示文摘AIM:To evaluate the risk factors-other than nonsteroidal anti-inflammatory drugs-for colonic diverticular bleeding in a westernized population. METHODS:One hundred and forty patients,treated for symptomatic diverticular disease in a community based hospital,were included.Thirty(21%) had signs of diverticular bleeding.Age,gender,and the results of colonoscopy were collected and compared to a group of patients with nonbleeding symptomatic diverticulosis.Records were reviewed for comorbidities,such as obesity,alcohol consumption,smoking habits and metabolic diseases.Special emphasis was put on arterial hypertension,cardiovascular events,diabetes mellitus,hyperuricemia and hypercholesterinemia. RESULTS:There was no difference between patients with diverticular hemorrhage and those with nonbleeding symptomatic diverticulosis regarding gender ratio(male/female 9/21 vs 47/63) and diverticular localisation.Bleeding patients differed in respect to age(73.4±9.9 vs 67.8±13.0,P<0.013) . Significant differences were found between both groups regarding the presence of hyperuricemia and use of steroids and nonsteroidal anti-inflammatory drugs.Patients with three concomitant metabolic diseases were also identified as being at risk of bleeding.A forward stepwise logistic regression analysis revealed steroids,hyperuricemia and the use of calcium-channel blockers as independent risk factors of bleeding.CONCLUSION:Beside nonsteroidal anti-inflammatory steroid drug use,antihypertensive medication and concomitant arteriosclerotic diseases are risk factors for colonic diverticular hemorrhage.Our results support the hypothesis of an altered arteriosclerotic vessel as the source of bleeding. | Antje Jansen Sabine Harenberg Uwe Grenda Christoph Elsing | 2009 | World Journal of Gastroenterology2009，15，4： | 3 |
| 2 | Implementation of a criti- cal pathway for distal pancreatectomy at an academic institution 显示文摘 | Kennedy EP Grenda TR Sauter PK | 2009 | Journal of Gastrointestinal Surgery2009，13，5： | 1 |
| 3 | Implementation of a cvitical pathaway for distal pancreatectomy at an academic institution显示文摘 | Kennedy EP Grenda TR Sauter PK | 2009 | J Gastrointest Surg2009，13，5： | 1 |
| 4 | Implementa-tion of a critical pathway for distal pancreatectomy at anacademic institution显示文摘 | Kennedy EP Grenda TR Sauter PK | 2009 | J Gastrointestinal Surg2009，13，5： | 1 |
| 5 | Determination of umequine and doxycycline in milk by a simple thin-layer chromatographic method 显示文摘 | Choma I Grenda D Malinowska I | 1999 | J Chromatogr B1999，，734： | 1 |
| 6 | Randomized trial of tacrolimus versus cyclosporin microemulsion in renal transplantation显示文摘 | Trompeter R Filler G Webb NJ Watson AR Milford DV Tyden G Grenda R Janda J Hughes D Ehrich JH Klare B Zacchello G Bjorn Brekke I McGraw M Perner F Ghio L Balzar E Friman S Gusmano R Stolpe J | 2002 | Pediatr Nephrol2002，17，3： | 1 |
| 7 | Urinary excretion of endothelin - 1 ( ET - 1 ) , transforming growth factor - betal ( TGF - betal ) and vascular endothelial growth factor (VEGF165) in paediatric chronic kidney diseases : Results of the ESCAPE trial 显示文摘 | Grenda R Wuhl E Litwin M | 2007 | Nephrol Dial Transplant2007，22，12： | 1 |
| 8 | Implementation of a Critical Pathway for Distal Pancreatectomy at an Academic Institution显示文摘 | Eugene P. Kennedy Tyler R. Grenda Patricia K. Sauter Ernest L. Rosato Karen A. Chojnacki Francis E. Rosato Jr Bernadette C. Profeta Cataldo Doria Adam C. Berger Charles J. Yeo | 2009 | Journal of Gastrointestinal Surgery2009，，5： | 1 |
| 9 | Margin positive pancreaticoduodenectomy is superior to palliative bypass in locallyadvanced pancreatic ductal adenocarcinoma显示文摘 | Lavu H Mascaro AA Grenda DR | 2009 | J Gastrointest Surg2009，13，11： | 1 |
| 10 | Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis 显示文摘 | Grenda DS Murakami M Ghatak J | 2007 | Blood2007，110，13： | 1 |
| 11 | Determination of flumequine and doxycycline in milk by asimple thin-lay chromatographic method显示文摘 | CHOMA I GRENDA D MALINOWSKA I | 1999 | J Chromatogr B1999，734，1： | 1 |
| 12 | Evaluation of the genetic background of standard-immunosup- pressant-related toxicity in a cohort of 200 paediatric renal allograft recipients-a retrospective study 显示文摘 | Grenda R Prokural S Ciechanowicz A | 2009 | Ann Transplant2009，14，3： | 1 |
| 13 | Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded response and cellular apoptosis显示文摘 | Grenda DS Murakami M Ghatak J | 2007 | Blood2007，110，13： | 1 |
| 14 | Intravenous calcitriol for treatment of hyperparathyroidism in children on hemodialysis显示文摘 | Greenbaum LA Grenda R Qiu P | 2005 | Pediatr Nephrol2005，20，5： | 1 |
| 15 | Determination of flumequine and doxycycline in milk by a simple thin-layer chromatographic method显示文摘 | Irena Choma Dorota Grenda Irena Malinowska Zdzis?aw Suprynowicz | 1999 | Journal of Chromatography B: Biomedical Sciences and Applications1999，，1： | 1 |
| 16 | Interaction between ACE I/D and ACTN3 R557X poly- morphisms in polish competitive swimmers显示文摘 | GRENDA A LEO H SKA-DUNIEC A KACZMARCZYK M | 2014 | J Hum Kinet2014，42，： | 1 |
| 17 | hn- plementation of a critical pathway for distal pancreatectomy at an a- cademic institution显示文摘 | Eugene P Kennedy Tyler R Grenda Jacqueline F Byers | 2009 | J Gastrointest Surg2009，13，5： | 1 |
| 18 | Implementation of a critical pathway for distal pancr- eatectomy at an academic institution显示文摘 | Eugene P Kennedy Tyler R Grenda Jacqueline F Byers | 2009 | J Gastrointest Surg2009，13，5： | 1 |
| 19 | Margin positive pancreaticoduodenectomy is superior to palliative bypass in locally advanced pancreatic ductal adenocarcinoma显示文摘 | Lavu H Mascaro AA Grenda DR | 2009 | J Gastrointest Surg2009，13，11： | 1 |
| 20 | Implementation of a critical pathway for distal pancreatectomy at an academic institution显示文摘 | Kennedy EP Grenda TR Sauter PK | 2009 | J Gastrointest Surg2009，13，5： | 1 |
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