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| 1 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 2 | Peripheral and mesenteric serum levels of CEA and cytokeratins,staging and histopathological variables in colorectal adenocarcinoma显示文摘瞄准:为了评估在外设和 mes 伤寒浆液之间存在的差别,与颜色在病人 carcinoembryonic 铺平抗原(CEA ) 和 cytokeratins 表面的腺癌。方法:有颜色的 138 个病人表面的腺癌在在 1993 年 12 月和 2000 年 3 月之间的医院 Sao Paulo (UNIFESP-EPM 的外科的肠胃病学的纪律) 经历了外科的人,回顾地被分析。CEA 和 cytokeratin (TPA-M ) 之间的差别在外部血(P) 并且在 mes 伤寒血(M) 的层次被学习。协会在外设和 mes 伤寒层次和阶段和组织病理学说的变量(细胞分化,宏观的外观,肿瘤尺寸和淋巴、静脉的侵略的存在的度) 之间被调查。结果:差别在标记层次的数字价值被观察:CEA (M)(39.10 mg/L +/- 121.19 mg/L ) 对 CEA (P)(38.5 mg/L +/- 122.55 mg/L ) , P <
0.05;TPA-M (M)(325.06 U/L +/- 527.29 U/L ) 对 TPA-M (P)(279.48 U/L +/- 455.81 U/L ) , P <
0.01。mes 伤寒 CEA 层次在更先进的肿瘤是更高的(P <
0.01 ) ,在生长损害(34.44 mg/L +/- 93.07 mg/L )(P <
0.01 ) 并且与静脉的侵略(48.41 mg/L +/- 129.86 mg/L )(P <
0.05 ) 。外部 CEA 与更先进的阶段是更高的(P <
0.01 ) 并且在有静脉的侵略的损害(53.23 mg/L +/- 158.57 mg/L )(P <
0.05 ) 。病人表明了有更多的 TPA-M 层次预付肿瘤的伤寒、外部的增加的 mes (P <
0.01 并且 P <
0.01 ) 并且在非溃烂的损害[530.45 U/L +/- 997.46 U/L (P <
0.05 ) 并且 457.95 U/L +/- 811.36 U/L (P <
0.01 )] 。结论:肿瘤标记 CEA 和 cytokeratins 的 mes 伤寒层次比在这些的外部层次渲染表面的腺癌病人高。这些生物学的肿瘤标记的高水平与癌的传播的一个先进状态被联系。 | Ivan Gregório Ivankovics Luis César Fernandes Sarhan Sydeney Saad Delcio Matos | 2008 | World Journal of Gastroenterology2008，14，43： | 4 |
| 3 | Osteopontin: a leading candidate adhesion molecule for implantation in pigs and sheep显示文摘Osteopontin(OPN; also known as Secreted Phosphoprotein 1, SPP1) is a secreted extra-cellular matrix(ECM) protein that binds to a variety of cell surface integrins to stimulate cell-cell and cell-ECM adhesion and communication. It is generally accepted that OPN interacts with apically expressed integrin receptors on the uterine luminal epithelium(LE)and conceptus trophectoderm to attach the conceptus to the uterus for implantation. Research conducted with pigs and sheep has significantly advanced understanding of the role(s) of OPN during implantation through exploitation of the prolonged peri-implantation period of pregnancy when elongating conceptuses are free within the uterine lumen requiring extensive paracrine signaling between conceptus and endometrium. This is followed by a protracted and incremental attachment cascade of trophectoderm to uterine LE during implantation, and development of a true epitheliochorial or synepitheliochorial placenta exhibited by pigs and sheep, respectively. In pigs, implanting conceptuses secrete estrogens which induce the synthesis and secretion of OPN in adjacent uterine LE. OPN then binds to αvβ6 integrin receptors on trophectoderm, and the αvβ3 integrin receptors on uterine LE to bridge conceptus attachment to uterine LE for implantation. In sheep, implanting conceptuses secrete interferon tau that prolongs the lifespan of CL. Progesterone released by CL then induces OPN synthesis and secretion from the endometrial GE into the uterine lumen where OPN binds integrins expressed on trophectoderm(αvβ3) and uterine LE(identity of specific integrins unknown) to adhere the conceptus to the uterus for implantation. OPN binding to the αvβ3 integrin receptor on ovine trophectoderm cells induces in vitro focal adhesion assembly, a prerequisite for adhesion and migration of trophectoderm, through activation of: 1) P70S6 K via crosstalk between FRAP1/MTOR and MAPK pathways; 2) MTOR,PI3 K, MAPK3/MAPK1(Erk1/2) and MAPK14(p38) signaling to stimulate trohectoderm cell migration; and 3) focal adhesion assembly and myosin II motor activity to induce migration of trophectoderm cells. Further large in vivo focal adhesions assemble at the uterine-placental interface of both pigs and sheep and identify the involvement of sizable mechanical forces at this interface during discrete periods of trophoblast migration, attachment and placentation in both species. | Greg A Johnson Robert C Burghardt Fuller W Bazer | 2015 | Journal of Animal Science and Biotechnology2015，6，2： | 4 |
| 4 | Activitybased costing accounting for a market orientation 显示文摘 | Daniel J G Greg W M William B C | 1998 | Industrial Marketing Management1998，，127： | 1 |
| 5 | Effect of loading parameters on the fatigue behavior of impact damaged composite laminates 显示文摘 | Milan M Hahn H T Greg P C | 1999 | Composites Science and Technology1999，59，14： | 1 |
| 6 | Campbell development of automatic, continuous partial discharge monitoring systems to detect motor and generator partial discharges显示文摘 | Greg C Stone Blake A Lloyd Steve R | 1997 | IEEE1997，，2： | 1 |
| 7 | Hysteretic modeling of wood joints and structural systems 显示文摘 | FOLIENTE Greg C | 1995 | Journal of Structural Engineering1995，，121： | 1 |
| 8 | Numerical simulation of explosion phenomena显示文摘 | Robertson N J Hayhurst C J Greg E F | 1994 | Ijcat1994，7，36： | 1 |
| 9 | Virtual instrumentation applied to monitoring of nuclear reactor refuel process 显示文摘 | Hurd Greg L Haun Melvin C | 1998 | Laboratory Robotics and Automation (S1098-2728)1998，10，2： | 1 |
| 10 | 显示文摘 | Greg P S Frederik C K Carl M L | 2008 | Sol Energy Mater Sol Cells2008，92，： | 1 |
| 11 | The free radical theory of aglng: A critical review显示文摘 | Roll JM Greg C | 1985 | Adv Free Radical Biol Med1985，1，1： | 1 |
| 12 | Containment of regulated genetically modified cotton in the field显示文摘 | DANNY L Chris T Greg C | 2007 | Agriculture Ecosys- tems & Environment2007，121，4： | 1 |
| 13 | Regulation of flowering in Arabidopsls by an FLC homologue 显示文摘 | Oliver J Ratcliffe Greg C Nadzan T Lynne Reuber et | 2001 | Plant Physiol2001，126，： | 1 |
| 14 | Analysis of patient variables affecting neurologic outcome after traumatic cervical facet dislocation显示文摘 | Greg Anderson D Voets C Ropiak R | 2004 | Spine J2004，4，5： | 1 |
| 15 | Anti-interleukin5 but not anti-IgE prevents airway inflammation and airway hyperresponsiveness显示文摘 | Eckard H Greg C Jorgen S | 1999 | Am J Respir Crit Care Med1999，160，3： | 1 |
| 16 | Chemoprevention of mouse intestinal tumorigenesis by the cyclin-dependent kinase inhibitor SNS-032显示文摘 | Amelie B Tina C Greg H E | 2009 | Cancer Prey Res (Phila)2009，2，9： | 1 |
| 17 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 1 |
| 18 | Macro-to-Micro links in the relation between income inequality and mortality显示文摘 | Mary C D Greg J D George A K | 1998 | The Milbank Quarterly1998，76，： | 1 |
| 19 | Dielectric spectroscopy of polystyrene/poly (ethylene oxide) composites 显示文摘 | Thomas W S Martin A A Greg C C | 1996 | Macromolecules1996，29，14： | 1 |
| 20 | Leac- hing and recovery of gold using ammoniacal thiosulfate leach liquors( a review) 显示文摘 | Andrew C Grosse Greg W Dicinoski Matthew J Shaw | 2003 | Hydrometallurgy2003，69，： | 1 |
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