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| 1 | Fluid resuscitation in acute pancreatitis: Normal saline or lactated Ringer's solution?显示文摘AIM: To investigate whether administration of Ringer's solution(RL) could have an impact on the outcome of acute pancreatitis(AP).METHODS: We conducted a retrospective study on 103 patients [68 men and 35 women,mean age 51.2 years(range,19-92 years)] hospitalized between 2011 and 2012. All patients admitted to the Department of Gastroenterology of the Central Clinical Hospital of the Ministry of Interior(Poland) with a diagnosis of AP who had disease onset within 48 h of presentation were included in this study. Based on the presence of persistent organ failure(longer than 48 h) as a criterion for the diagnosis of severe AP(SAP) and the presence of local complications [diagnosis of moderately severe AP(MSAP)],patients were classified into 3 groups: mild AP(MAP),MSAP and SAP. Data were compared between the groups in terms of severity(using the revised Atlanta criteria) and outcome. Patients were stratified into 2 groups based on the type of fluid resuscitation: the 1-RL group who underwent standard fluid resuscitation with a RL 1000 m L solution or the 2-NS group who underwent standard fluid resuscitation with 1000 m L normal saline(NS). All patients from both groups received an additional 5% glucose solution(1000-1500 m L) and a multi-electrolyte solution(500-1000 m L).RESULTS: We observed 64(62.1%) patients with MAP,26(25.24%) patients with MSAP and 13(12.62%) patients with SAP. No significant difference in the distribution of AP severity between the two groups was found. In the 1-RL group,we identified 22(55.5%) MAP,10(25.5%) MSAP and 8(20.0%) SAP patients,compared with 42(66.7%) MAP,16(24.4%) MSAP and 5(7.9%) SAP cases in the 2-NS group(P = 0.187). The volumes of fluid administered during the initial 72-h period of hospitalization were similar among the patients from both the 1-RL and 2-NS groups(mean 3400 m L vs 3000 m L,respectively). No significant differences between the 1-RL and 2-NS groups were found in confirmed pancreatic necrosis [10 patients(25%) vs 12 patients(19%),respectively,P = 0.637]. There were no statistically significant differences between the 1-RL and 2-NS groups in the percentage of patients who required enteral nutrition(23 patients vs 17 patients,respectively,P = 0.534). Logistic regression analysis confirmed these findings(OR = 1.344,95%CI: 0.595-3.035,P = 0.477). There were no significant differences between the 1-RL and 2-NS groups in mortality and the duration of hospital stay(median of 9 d for both groups,P = 0.776).CONCLUSION: Our study failed to find any evidence that the administration of RL in the first days of AP leads to improved clinical outcomes. | Michal Lipinski Alicja Rydzewska-Rosolowska Andrzej Rydzewski Grazyna Rydzewska | 2015 | World Journal of Gastroenterology2015，21，31： | 21 |
| 2 | Loss of FHIT expression in gastric mucosa of patients with family histories of gastric cancer and Helicobacter pylori infection显示文摘AIM: To answer the question whether FHIT gene expression is affected by the family history of gastric carcinoma and the presence of Helicobacter pylori (Hpylori) in the gastric mucosa of patients with dyspepsia.METHODS: FHIT gene expression in two different topographic sites of the gastric mucosa of twenty-one patients with dyspepsia and with or without familial gastric carcinoma, infected or not infected with H pylori, was evaluated by reverse transcription-PCR (RT-PCR) and IMAGE QUANT methods. A rapid urease test and histopathological examination were used to determine H pylori colonization.RESULTS: In the gastric mucosa of patients with family histories of gastric carcinoma, the amount of FHIT protein mRNA was reduced down to 32%, and for patients with H pylori colonization, to 24% in comparison to controls with dyspepsia and without cancer in the family. FHIT expression was independent of the topography of specimens (corpus vsantrum), and for the control patients it was less sensitive to infection with H pylori. A considerable statistical difference in FHIT levels was observed in the gastric mucosa from the corpus of patients with family histories of gastric carcinoma in respect to H pylori colonization (P = 0.06). Macroscopic evaluation of the gastric mucosa demonstrated that pathologic changes classified according to the Sydney system had no significant influence on FHIT expression within each tested group of patients.CONCLUSION: Loss of FHIT expression was observed in patients with dyspepsia and family histories of gastric carcinoma, especially those infected with H pylori. Such results may constitute an early indication of the development of gastric carcinoma, which is associated with family factors including heredity and H pylori infection. The loss of the FHIT gene may serve as a marker for early diagnosis and prevention of gastric carcinoma, especially in context of early monitoring of H pylori infection in individuals with a record of familial stomach cancer. | Krystyna Stec-Michalska Slawomir Antoszczyk Grazyna Klupinska Barbara Nawrot | 2005 | World Journal of Gastroenterology2005，11，1： | 17 |
| 3 | 不同改性Hummers法合成氧化石墨(英文)显示文摘通过不同的Hummers法和重铬酸钠氧化法,以商业石墨为原料,合成出不同氧含量和官能团的氧化石墨。采用元素分析、FTIR、XPS、SEM和XRD对氧化石墨进行化学和结构表征。重铬酸钾氧化能得到一种氧含量低的氧化石墨,主要形成羟基和环氧基。Hummers法是更有效的一种氧化方法。使用Na NO3氧化2 h,得到的氧化石墨具有最高的氧含量(>40 wt%),形成C—O和C=O键。SEM和XRD结果表明,在这些条件中,Hummers法合成的氧化石墨的石墨层间距最大。因此,用相同的氧化方法,通过改变反应条件能调控氧化石墨的化学结构。 | Roksana Muzyka Monika Kwoka Lukasz Smedowski Noel Díez Grazyna Gryglewicz | 2017 | 新型炭材料2017，32，1： | 16 |
| 4 | 云南常见牛肝菌属真菌中汞含量及食用安全评价显示文摘汞(Hg)是危害人类健康的主要重金属元素之一,多数食用菌对Hg有很强的富集能力,测定食用菌中Hg含量,并对其进行食用安全性评价具有重要意义。采用冷原子吸收直接测汞仪系统测定85份云南常见牛肝菌属真菌菌盖、菌柄中总Hg含量;以同一牛肝菌子实体菌盖与菌柄总Hg含量比(Q(C/S))分析牛肝菌属真菌对Hg的富集特征;根据联合国粮农组织和世界卫生组织(FAO/WHO)现行每周Hg允许摄入量(provisional tolerable week—lyintake,PTWI)标准和中国GB2762—2012规定的食用菌中Hg限量标准评价样品的食用安全性。结果表明,菌盖和菌柄中总Hg含量分别在0.13—22.00、0.20~8.40mg·kg^-1DW,不同产地、种类及不同采集年份的样品中总Hg含量存在明显差异;同一牛肝菌菌盖、菌柄总Hg含量比(Q(C/S))在0.28~4.08,92%的样品Q((C/S))〉1,表明多数样品中菌盖对Hg的富集能力强于菌柄。根据GB2762-2012规定的食用菌及其制品中总Hg含量限量标准(≤0.1mg·kg^-1),发现所有测试样品的总Hg含量均超标;根据PTWI标准,假设成年人(60kg)每周食用300g新鲜牛肝菌,则多数样品Hg摄入量低于允许摄入量,无安全风险,而少数样品Hg摄入量高于允许摄入量,食用有一定的潜在风险。同时,牛肝菌总Hg含量与种类、产地、采集时间等因素密切相关,采食及安全评价需综合考虑这些因素。 | 杨天伟 张霁 Jerzy FALANDYSZ Grazyna KRASIИSKA Martyna SABA 王元忠 刘鸿高 | 2015 | 生态学杂志2015，34，12： | 12 |
| 5 | N-acetylcysteine does not prevent post-endoscopic retrograde cholangiopancreatography hyperamylasemia and acute pancreatitis显示文摘瞄准:尖锐胰腺炎(AP ) 是最普通、经常严重的复杂并发症内视镜后退 cholangiopancreatography (ERCP ) 。在尖锐胰腺炎的致病的早步可能是毛状的内皮损害由导出氧的自由基调停了。N-acetylcysteine - 自由基 scavenger 可能在阻止尖锐胰腺炎和它是的 post-ERCP 是潜在地有效的也知道那个 N-acetylcysteine (ACC ) 罐头在 AP 的试验性的模型减少疾病的严厉。方法:106 个病人随机被分配到二个组。55 个病人被给 N-acetylcysteine (口头上地,在 ERCP 和 600 mg 前的 24 和 12 h 被给 iv 的二 600 mg 剂量,两次为在 ERCP 以后的二天的一天) 。控制组由被给 iv 的 51 个病人组成了。等渗盐两次为在 ERCP 以后的二天的一天。浆液和尿淀粉酶活动在过程以后在 ERCP 和 8 和 24 h 前被测量。主要结果参数是尖锐胰腺炎和第二等的结果参数是的 post-ERCP 在浆液和尿淀粉酶活动的组之间的差别。结果:处于在二个组之间的 post-ERCP 胰腺炎的率没有有效差量(10 病人外套, 4 在 ACC 组织, 6 在控制组织) 。也在在 ACC 组和控制组之间的基线和 post-ERCP 浆液和尿淀粉酶活动没有有效差量。结论:N-acetylcysteine 没能在 post-ERCP 胰腺炎上,以及在浆液和尿淀粉酶活动上表明任何重要预防效果。 | Janusz Milewski Grazyna Rydzewska Malgorzata Degowska Maciej Kierzkiewicz Andrzej Rydzewski | 2006 | World Journal of Gastroenterology2006，12，23： | 10 |
| 6 | Nitric Oxide in Plants: Production and Cross-talk with Ca^2+ Signaling显示文摘氮的氧化物(没有) 是在动物在生理的过程的一个宽数组执行关键功能的两价的气体。过去的几年在植物关于它的角色揭示了大部分。被硝酸盐 reductase (NR ) 并且经由化学小径不从亚硝酸根综合,这很好被建立。为没有生产是从由到目前为止非识别的酶的 L 精氨酸的 catalysed 的一条其他的在小径的出现正在增加证据。矛盾的结果处于特定的生理的条件关于这些酶的各自的参与被报导了。尽管大部分尚待被证明,我们假设这些矛盾能被说明因为由过去常不压制合成的药理学代理人的有限特性而且由象在硝酸盐的硝酸盐可渗透的阴离子隧道的迟钝一样的 L 精氨酸的减少的内容 reductase- 或 nitrate/nitrite-deficient 种。另一个未解决的问题使不在植物位于效果下面的分子的机制担心。这里,我们提供证据包括 MAPK 和 SnRK2 的第二送信人 Ca2+ ,以及蛋白质 kinases,是很嘴巧的调停人没有信号。这些调查结果关于在植物的不基于的发信号的开的新观点。 | Angelique Besson-Bard Cecile Courtois Adrien Gauthier Jennifer Dahan Grazyna Dobrowolska Sylvain Jeandroz Alain Pugin David Wendehenne | 2008 | Molecular Plant2008，1，2： | 9 |
| 7 | Coexistence of hepatocellular carcinoma and gastrointestinal stromal tumor:A case report显示文摘恶意的胃肠的基质肿瘤(大意) 是从胃肠道的墙发源的稀罕间充质的肿瘤。他们有从另外的胚层发源的另外的肿瘤的共存是唯一的。我们报导了作为与肝的肿瘤联系的一个腹上部的团介绍的一个 63 岁的大意病人的一个案例。组织学地, mes 伤寒肿瘤由棱形细胞出现组成神经并且平滑肌区别。Immunohistochemical 检查显示出为 CD117, vimentin, S-100,和 SMA 的积极染色,当 CD34 抗原是否定的时。肝的肿瘤作为肝细胞癌(HCC ) 被诊断。就我们的知识而言,这是大意和 HCC 共存的第一个案例。然而,案例的稀有不应该导致在鉴别诊断忽略如此的可能性。 | RadoslawJaworski TomaszJastrzebski MaciejSwierblewski KamilDrucis Grazyna Kobierska-Gulida | 2006 | World Journal of Gastroenterology2006，12，4： | 9 |
| 8 | Secretion of melatonin and 6-sulfatoxymelatonin urinary excretion in functional dyspepsia显示文摘AIM:To evaluate blood concentration of melatonin and urinary excretion of its metabolite,6-sulfatoxymelatonin(6-OHMS),in functional dyspepsia(FD).METHODS:Ninety individuals were enrolled in the study:30 in each study group:patients with postprandial distress syndrome(PDS),epigastric pain syndrome(EPS),and controls.Blood samples were drawn at 02:00 and 09:00 h and 24-h urine collection was performed.Serum melatonin and urinary 6-OHMS concentrations were measured by enzyme-linked immunosorbent assay.RESULTS:Serum melatonin concentration at night and in the morning was significantly(P < 0.001) higher in PDS patients [at 02:00 h-93.3 pg/mL,quartile range(QR):79.8-116.2;at 09.00 h-14.3 pg/mL,QR:7.06-19.0] than in EPS(57.2 pg/mL,QR:42.6-73.1;8.1 pg/mL,QR:4.1-9.3) and control patients(57.7 pg/mL,QR:51.2-62.5;8.1 pg/mL,QR:5.4-10.3).A similar relationship was observed for urinary 6-OHMS excretion.Patients with severe PDS symptoms had a higher melatonin concentration than these with moderate syndromes,whereas patients with severe EPS had a lower urinary 6-OHMS excretion than patients with moderate symptoms.CONCLUSION:Evaluation of melatonin serum concentrations and 24-h urinary 6-OHMS excretion are useful methods for differential diagnosis of various clinical forms of FD. | Cezary Chojnacki Tomasz Poplawski Grazyna Klupinska Janusz Blasiak Jan Chojnacki Russel J Reiter | 2011 | World Journal of Gastroenterology2011，17，21： | 8 |
| 9 | Evaluation of enterochromaffin cells and melatonin secretion exponents in ulcerative colitis显示文摘AIM: To study an assessment of the number of enterochromaffin cells and expression of hydroxyindole-Omethyltransferase in colonic mucosa and urine excretion of 6-sulfatoxymelatonin in patients with ulcerative colitis. METHODS: The study included 30 healthy subjects (groupⅠ-C), 30 patients with ulcerative proctitis [group Ⅱ-ulcerative proctitis (UP)] and 30 patients with ulcerative colitis [group Ⅲ-ulcerative colitis (UC)] in acute phases of these diseases. The number of enterochromaffin cells (EC) was estimated in rectal and colonic mucosa. Bioptates were assembled from many different parts of the large intestine. Immunorective cells collected from various parts of the colon were counted according to the Eurovision DAKO (Dako A/S, Copenhagen, Denmark) System in the range of 10 fields in each bioptate at × 200 magnification. The level of mRNA expression of hydroxyindole-O-methyltransferase (HIOMT) in colonic mucosa was estimated with RT-PCR. Urine 6-sulfatoxymelatonin (6-HMS) excretion was determined immunoenzymatically using an IBL (IBL International GmbH, Hamburg, Germany) kit (RE 54031). RESULTS: The number of EC cells in healthy subjects (C) was 132.40 ± 31.26. In patients of group Ⅱ (UP) and group Ⅲ (UC) the number of these cells was higher 225.40 ± 37.35 (P < 0.001) and 225.24 ± 40.50 (P < 0.001) respectively. Similar differences were related to HIOMT expression, which was 1.04 ± 0.36 in group C, 1.56 ± 0.56 (P < 0.01) in group UP and 2.00 ± 0.35 (P < 0.001) in group UC. Twenty-four hour 6-HMS urinary excretion was as follows: C 16.32 ± 4.95 μg/24 h, UP 26.30 ± 7.29 μg/24 h (P < 0.01), UC 42.30 ± 12.56 μg/24h (P < 0.001). A correlation between number of EC cells and 6-HMS excretion was noted in all groups: r = 0.766 in patients with UP, r = 0.703 with UC and r = 0.8551 in the control group; the correlation between the results is statistically significant. CONCLUSION: In the acute phases of both UP and UC, proliferation of EC cells and high expression of HIOMT and urine excretion of 6-HMS is noted. These changes may represent a beneficial response in the anti-inflammatory and defense mechanism. | Cezary Chojnacki Maria Wisniewska-Jarosińska Grazyna Kulig Ireneusz Majsterek Russel J Reiter Jan Chojnacki | 2013 | World Journal of Gastroenterology2013，19，23： | 5 |
| 10 | Factors associated with irritable bowel syndrome symptoms in hemodialysis patients显示文摘AIM: To investigate clinical characteristics associated with the presence of irritable bowel syndrome (IBS) symptoms in hemodialysis (HD) patients.METHODS: This was a cross-sectional study. A questionnaire based on the Bowel Disease Questionnaire that records gastrointestinal symptoms was given to 294 patients in 4 dialysis centers. A total of 196 (67%) subjects returned the survey. A multivariable logistic regression model was used to identify factors significantly associated with IBS symptoms. RESULTS: Symptoms compatible with IBS were present in 27 (13.8%) subjects and independently associated with low post-dialysis serum potassium [OR = 0.258, 95% CI (0.075-0.891), P = 0.032], paracetamol use [OR = 3.159, 95% CI (1.214-8.220), P = 0.018], and Kidney Disease Quality of Life (KDQOL) cognitive function score [OR = 0.977, 95% CI (0.956-0.999), P = 0.042]. Univariate regressions were also performed and the reported significance is for multivariate analysis. No association was detected for age, gender, depressed mood, smoking (present or past), body mass index, albumin level, Kt/V, sodium preor post-dialysis level, change in potassium level during HD, proton pump inhibitor or H2 blocker use, aspirin use, residual diuresis, hepatitis B or C infection, diabetes mellitus, marital status and education level. CONCLUSION: This study examined potential risk factors for symptoms compatible with IBS in HD patients and identified an association with paracetamol use, post-dialysis potassium level and KDQOL-cognitive function score. | Bartosz Fiderkiewicz Alicja Rydzewska-Rosoowska Micha Myliwiec Magdalena Birecka Bozenna Kaczanowska Grazyna Rydzewska Andrzej Rydzewski | 2011 | World Journal of Gastroenterology2011，17，15： | 5 |
| 11 | 云南省野生牛肝菌总汞含量测定分析及健康风险评估显示文摘【目的】系统测定云南常见野生牛肝菌中总Hg含量,分析不同产地、种类及不同部位牛肝菌对Hg的富集规律和积累特征,评价野生牛肝菌的食用安全性,为野生食用菌产业的发展和食用安全评估提供数据依据。【方法】采用MA-2000直接测Hg仪—冷原子吸收光谱法测定牛肝菌菌盖、菌柄中总Hg含量,计算同一牛肝菌菌盖与菌柄总Hg含量比(QC/S),分析不同种类、部位牛肝菌中总Hg含量的差异和富集规律。根据中国《食品安全国家标准食品中污染物限量》(GB 2762—2012)规定的食用菌中Hg限量标准及联合国粮农组织和世界卫生组织(FAO/WHO)规定的每周Hg允许摄入量(provisional tolerable weekly intake,PTWI)现行标准,评价云南野生牛肝菌的食用安全性。【结果】同一子实体菌盖与菌柄的比值(QC/S)在0.3~8.8之间,95%牛肝菌样品菌盖、菌柄总Hg含量比(QC/S)≥1,表明多数牛肝菌菌盖对Hg的富集能力强于菌柄。本研究中多数野生牛肝菌菌盖、菌柄总Hg含量超过GB 2762—2012规定的食用菌中Hg含量限量标准(≤0.1 mg/kg);根据PTWI标准,假设成年人(60 kg)每周食用300 g新鲜牛肝菌,则多数样品Hg摄入量低于允许摄入量,无安全风险,而2013年采自玉溪大营街的美味牛肝菌,2012年采自楚雄永仁县的铜色牛肝菌及2014年采自玉溪新平的绒柄牛肝菌等少数样品Hg摄入量高于该标准。【结论】不同产地、种类牛肝菌菌盖、菌柄中总Hg含量存在明显差异,有少数牛肝菌总Hg含量超过相关标准,食用具有一定的潜在风险。 | 李杰庆 杨天伟 张霁 Jerzy FALANDYSZ Grazyna KRASINSKA Martyna SABA 王元忠 刘鸿高 | 2017 | 云南农业大学学报(自然科学版)2017，32，3： | 4 |
| 12 | Trace Elements in Leccinum scabrum Mushrooms and Topsoils from K odzka Dale in Sudety Mountains, Poland显示文摘In the current study, we determined concentrations and transfer rates of Ag, Al, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, Pb, P, Rb, Sr and Zn to Brown Birch Scaber Stalks (Leccinum scabrum) mushrooms emerged in the area of Sudety Mountains (Sudetes) in Poland. Fruiting bodies and topsoil samples beneath L. scabrum were collected form the K odzka Dale. The trace elements were determined using validated method and inductively coupled plasma - atomic emission spectroscopy (ICP-AES) for final measurement. Mushrooms contained Ag, Cr, Hg, Co, Ni and Sr at < 1.0 μg/g dry weight; Ba and Pb at ~1.0 μg/g dw; Cd at < 5 μg/g dw; Cu and Mn at > 10 μg/g dw; Al and Ca at ~100 μg/g dw; Fe, Na, Rb and Zn at 100 to 500 μg/g dw, Mg at ~1,000 μg/g dw; P at ~5,000 μg/g dw and K at ~30,000 μg/g dw. Ca, Mn and Ni were nearly equally distributed between stipes and caps; stipes compared to caps were enriched in Ba, Na and Sr, while caps were enriched in Ag, Al, Cd, Co, Cr, Cu, Fe, K, P, Pb, Rb and Zn. The values of bioconcentration factor (BCF) varied highly depending on chemical element and were >1 for Ag, Cd, Cu, K, Mg, Na, P, Rb and Zn, while <1 for Al, Ba, Ca, Co, Cr, Fe, Mn, Ni, Pb and Sr. Topsoil showed elevated content of lead and mean concentration was 99 ± 32 μg/g dw, while cadmium was at 0.41 ± 0.15 and those two highly toxic to human elements occurred in edible caps of L. scabrum at 4.5 ± 2.2 and 2.9 ± 2.0 μg/g dw, respectively. | ZHANG Dan ZHANG Yu MORAWSKA Ewa BIELAWSKI Leszek KRASINSKA Grazyna DREWNOWSKA Ma gorzata PANKAVEC Sviatlana SZYMANSKA Karolina FALANDYSZ Jerzy | 2013 | Journal of Mountain Science2013，10，4： | 4 |
| 13 | Microenvironment Elements Involved in the Development of Pancreatic Cancer Tumor显示文摘 | Katarzyna Gardian S?awa Janczewska Marek Durlik Grazyna Rydzewska | 2012 | Gastroenterology Research and Practice2012，，： | 2 |
| 14 | 血糖控制良好的2型糖尿病患者血清VEGF-A及其受体VEGFR1和VEGFR2含量检测(英文)显示文摘研究目的:探讨血糖控制良好的2型糖尿病患者血管内皮生长因子-A(VEGF-A)及其受体VEGFR1和VEGFR2含量及其临床意义。研究方法:本文以31例血糖得到良好控制且没有明显大血管或微血管病变的2型糖尿病患者作为研究对象(实验组),30位健康志愿者为对照组,同期检测患者及健康志愿者的空腹血糖、血脂、糖化血红蛋白水平,及血清VEGF-A、VEGFR1和VEGFR2含量,并加以比较和统计学分析。重要结论:研究结果表明,血糖控制良好的2型糖尿病患者血清中的VEGF-A及其受体VEGFR1和VEGFR2的含量和健康志愿者基本一致,两者无统计学意义,这可能显示血糖水平的合理控制能延缓血管并发症的产生。同时,2型糖尿病患者的血清VEGFR2含量和高密度脂蛋白胆固醇水平之间存在负相关,而血清VEGF-A、VEGFR2含量和甘油三脂水平之间存在正相关,这也表明糖尿病患者的血脂紊乱可能参与了血管生成的调节。 | Barbara RUSZKOWSKA-CIASTEK Alina SOKUP Maciej W. SOCHA Zofia RUPRECHT Lidia HALAS Barbara GóRALCZYK Krzysztof GóRALCZYK Grazyna GADOMSKA Danuta ROSC | 2014 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2014，15，6： | 2 |
| 15 | TT virus infection and pancreatic cancer: Relationship or accidental coexistence显示文摘TT virus (TTV) was first isolated in 1997 from the patient with acute post-transfusion hepatitis. This fact led to the conclusion that the virus was hepatotropic and could be one of the causative agents of acute hepatitis. Afterwards, however, the virus was found in other human tissues and serological studies revealed that it was widespread. Multiple tropisms of TTV and the fact of its high incidence in general population are considered to indicate no medical significance of TTV in human pathology. Here we present a report of two cases of TTV infection in patients who developed pancreas cancer. The patients were hospitalized at the Department of Infectious Diseases due to hepatitis of unknown origin. Since serological and virological markers of common primary and secondary hepatotropic viruses were negative, TTV-DNA was found in serum and was believed to be the only causative agent with probable hepatotropic action. The patients later developed pancreas cancer and they underwent operation. The relationship is difficult to confirm, however the cases we present should be treated as a preliminary report and a comment on the real role of TTV in human pathology. | Krzysztof Tomasiewicz Roma Modrzewska Anna Lyczak Grazyna Krawczuk | 2005 | World Journal of Gastroenterology2005，11，18： | 2 |
| 16 | Detection of PAHs in seawater using surface-enhanced Raman scattering (SERS)显示文摘 | Heinar Schmidt Nguyen Bich Ha Jens Pfannkuche Hans Amann Heinz-Detlef Kronfeldt Grazyna Kowalewska | 2004 | Marine Pollution Bulletin2004，，3： | 2 |
| 17 | A study of mechanisms responsible for incorporation of cesium and radiocesium into fruitbodies of king oyster mushroom( Pleurotus eryngii ) 显示文摘 | Grazyna Bystrzejewska-Piotrowska Michal A Bazata | 2008 | Journal of Enviromental Radioactivity2008，99，7： | 1 |
| 18 | Cloning,sequencing,and regulation of the glutathione reductase gene from the Cyanobacterium anabaena PCC 7120显示文摘 | Fanyi J Ulf H Grazyna E S | 1995 | J Biol Chem1995，270，22： | 1 |
| 19 | Note on the karyotype and NOR location of Siamese fighting fish Betta splendens (Perciformes, Osphronemidae)显示文摘 | Grazyna F S Fopp B D Jankun M | 2008 | Caryologia2008，61，4： | 1 |
| 20 | Surface activity of cationic surfactants, influence of molecular structure 显示文摘 | GRAZYNA PARA AGNIESZKA HAMERSKA - DUDRA KAZIMI- ERA ANNA WILK | 2010 | Colloids and Surfaces A:Physicochemical and Engineering Aspects2010，365，123： | 1 |
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