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	题名	作者	年代	出处	被引量
1	Molecular and systemic mechanisms of general anaesthesia: the ‘ multi - site and multiple mechanisms' concept 显示文摘	Grasshoff C Rudolph U Antkowiak B	2005	Curr Opin Anaesthesiol2005，18，4：	1
2	Disbography findings and results of percuta neous laser disk decomp ression(PLDD)显示文摘	Grasshoff H Kayser R Mahlfeld U etal	2001	Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr2001，173，3：	1
3	Diverse morphology of biliary atresia in an animal model显示文摘	Petersen C Grasshoff S Luciano L	1998	J Hepatol1998，28，4：	1
4	Efects of propofol on N-methyl-D-aspartatereceptor-mediated calcium increase in cultured rat cerebrocorticalneurons显示文摘	Grasshoff C Gillessen T	2005	Eur J Anaesthesiol2005，22，6：	1
5	Diverse morphology of biliary atresia in an animal model显示文摘	Petersen C Grasshoff S Luciano L	1998	J Hepatol1998，28，：	1
6	Contributors to individual quality of life after liver transplantation显示文摘	Christian Thiel Kerstin Landgrebe Evelyn Knubben Silvio Nadalin Ruth Ladurner Christian Grasshoff Alfred K?nigsrainer Martin Schenk Karolin Thiel	2012	European Journal of Clinical Investigation2012，，1：	1
7	Propofol and sevoflurane depress spinal neurons in vitro via different molecular targets 显示文摘	GRASSHOFF C ANTKOWIAK B	2004	Anesthesiology2004，101，5：	1
8	Propofol and sevoflurane depress spinal neurons in vitro via different molecular targets 显示文摘	Grasshoff C Antkowiak B	2004	Anesthesiology2004，101，5：	1
9	Mitochondrial permea-bility transition can be directly monitored in living neurons显示文摘	Gillessen T Grasshoff C Szinicz L	2002	Biomed Pharmacother2002，56，4：	1
10	Efects of propofol on N-methyl-D-aspartate receptor-mediated calcium increase in cultured rat cerebrocortical neurons显示文摘	Grasshoff C Gillessen T	2005	Eur J Anaesthesiol2005，22，6：	1
11	Porcine model characterizing various parameters assessing the outcome after acetaminophen intoxication induced acute liver failure显示文摘AIM To investigate the changes of hemodynamic and laboratory parameters during the course of acute liver failure following acetaminophen overdose.METHODS Eight pigs underwent a midline laparotomy following jejunal catheter placement for further acetaminophen intoxication and positioning of a portal vein Doppler flow-probe. Acute liver failure was realized by intrajejunal acetaminophen administration in six animals, two animals were sham operated. All animals were invasively monitored and received standardized intensive care support throughout the study. Portal blood flow, hemodynamic and ventilation parameters were continuously recorded. Laboratory parameters were analysed every eight hours. Liver biopsies were sampled every 24 h following intoxication and upon autopsy.RESULTS Acute liver failure (ALF) occurred after 28 ± 5 h resulted in multiple organ failure and death despite maximal support after further 21 ± 1 h (study end). Portal blood flow (baseline 1100 ± 156 m L/min) increased to a maximum flow of 1873 ± 175 m L/min at manifestation of ALF, which was significantly elevated(P < 0.01). Immediately after peaking, portal flow declined rapidly to 283 ± 135 m L/min at study end. Thrombocyte values (baseline 307 × 103/μL± 34 × 103/μL) of intoxicated animals declined slowly to values of 145 × 103/μL± 46 × 103/μL when liver failure occurred. Subsequent appearance of severe thrombocytopenia in liver failure resulted in values of 11 × 103/μL± 3 × 103/μL preceding fatality within few hours which was significant(P > 0.01).CONCLUSION Declining portal blood flow and subsequent severe thrombocytopenia after acetaminophen intoxication precede fatality in a porcine acute liver failure model.	Karolin Thiel Wilfried Klingert Kathrin Klingert Matthias H Morgalla Martin U Schuhmann Pamela Leckie Yalda Sharifi Nathan A Davies Rajiv Jalan Andreas Peter Christian Grasshoff Alfred Konigsrainer Martin Schenk Christian Thiel	2017	World Journal of Gastroenterology2017，23，9：	1
12	Molecular and systemic mechanisms of general anaesthesia: the ' multisite and multiple mechanisms' concept显示文摘	Grasshoff C Rudolph U Antkowiak B	2005	Curr Opin Anaesthesiol2005，18，：	1
13	The Hydrochemistry of Landlocked Basins and Fjords显示文摘	GRASSHOFF K	1974	Chemical Oceanography1974，2，：	1
14	Permanent thoracic myelopathy resulting from herniation of a calcified intervertebral disc in a child显示文摘	Mahlfeld K Kayser R Grasshoff H	2002	Pediatr Orthop2002，11，：	1
15	The effect of acetylcholinesterase- inhibition on depolarization-induced GABA release from rat striatal slices 显示文摘	GRASSHOFF C GILLESSEN T THIERMANN H	2003	Toxicol2003，184，23：	1
16	Fibroblasts surrounding melanoma express elevated levels of matrix metalloproteinase-1 (MMP-1) and intercellular adhesion molecule-1(ICAM-1) in vitro显示文摘	Wandel E Grasshoff A Mittag M	2000	Exp Dermatol2000，9，1：	1
17	Diverse morphology of biliaryat resia in a animal modle 显示文摘	Petersen C Grasshoff S Luciano L	1998	J Hepatol1998，28，：	1
18	Zur bestimmung von nitrat in Meer-und Trinkwasser显示文摘	Grasshoff K	1964	Kieler Meeresforschungen1964，20，1：	1
19	De novo MECP2 duplication in two females with random X-inactivation and moderate mental retardation 显示文摘	Grasshoff U Bonin M Goehring I	2011	Eur J Hum Genet2011，19，5：	1
20	Effects of propofol on N - methyl - D - asparate receptor - mediated calcium increase in cultured rat cerebrocortical neurons 显示文摘	Grasshoff C Gillessen T	2005	Eur J Anaesthesiol2005，22，6：	1

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