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| 1 | Single-cell omics analyses with single molecular detection:challenges and perspectives显示文摘The ultimate goal of single-cell analyses is to obtain the biomolecular content for each cell in unicellular and multicellular organisms at different points of their life cycle under variable environmental conditions.These require an assessment of:a)the total number of cells,b)the total number of cell types,and c)the complete and quantitative single molecular detection and identification for all classes of biopolymers,and organic and inorganic compounds,in each individual cell.For proteins,glycans,lipids,and metabolites,whose sequences cannot be amplified by copying as in the case of nucleic acids,the detection limit by mass spectrometry is about 105 molecules.Therefore,proteomic,glycomic,lipidomic,and metabolomic analyses do not yet permit the assembly of the complete single-cell omes.The construction of novel nanoelectrophoretic arrays and nano in microarrays on a single 1-cm-diameter chip has shown proof of concept for a high throughput platform for parallel processing of thousands of individual cells.Combined with dynamic secondary ion mass spectrometry,with 3D scanning capability and lateral resolution of 50 nm,the sensitivity of single molecular quantification and identification for all classes of biomolecules could be reached.Further development and routine application of such technological and instrumentation solution would allow assembly of complete omes with a quantitative assessment of structural and functional cellular diversity at the molecular level. | Gradimir Misevic | 2021 | The Journal of Biomedical Research2021，35，4： | 4 |
| 2 | Uric acid levels in sera from patients with multiple sclerosis显示文摘 | Jelena Drulovi? Irena Dujmovi? Neboj?a Stojsavljevi? ?arlota Mesaro? Slobodanka Andjelkovi? Djordje Miljkovi? Vesna Peri? Gradimir Dragutinovi? Jelena Marinkovi? Zvonimir Levi? Marija Mostarica Stojkovi? | 2001 | Journal of Neurology2001，，： | 1 |
| 3 | Design of Shell-and-Tube Heat Exchangers by Using CFD Technique Part one: Thermo Hydraulic Calculation 显示文摘 | Zarko Stevanovie Gradimir Ilic Nenad Radojkovie | 2001 | Me chanical Engineering2001，8，1： | 1 |
| 4 | Apoptosis in Bone Marrow of Myelodysplastic Syndrome Patients显示文摘 | Gradimir M Jankovic | 1996 | Blood1996，87，： | 1 |
| 5 | Apoptosis in bone marrow of myelodysplastic syndrome patients显示文摘 | Bogdanovic AD Gradimir M Jankovic | 1996 | Blood1996，87，7： | 1 |
| 6 | Uric acid levels in sera from patients with multiple sclerosis显示文摘 | Jelena Drulovi? Irena Dujmovi? Neboj?a Stojsavljevi? ?arlota Mesaro? Slobodanka Andjelkovi? Djordje Miljkovi? Vesna Peri? Gradimir Dragutinovi? Jelena Marinkovi? Zvonimir Levi? Marija Mostarica Stojkovi? | 2001 | Journal of Neurology2001，，2： | 1 |
| 7 | Design of Shell - and - Tube Heat Exchangers by Using CFD Technique - Part one 显示文摘 | Zarko Stevanovic Gradimir Ilic Nenad Radojkovic etc | 2001 | Thermo - Hydraulic Calculation Mechanical Engineering2001，8，1： | 1 |
| 8 | A new approach to the prediction and design of shell and tube heat exchangers 显示文摘 | MICA Vukic GRADIMIR Ilic NENAD Radojkovic el al | 2000 | Mechanical Engineering2000，1，7： | 1 |
| 9 | Binary relations and algebras on multisets显示文摘 | Silvia G Jovanka P Gradimir V | 2014 | Publications De Linstitut Matbematique2014，95，109： | 1 |
| 10 | Reliability allocation application in vehicle design显示文摘 | Ivanovic Gradimir | 2000 | International Journal of Vehicle Design2000，24，2： | 1 |
| 11 | The reliability allocation application in vehicledesign 显示文摘 | Gradimir lvanovic | 2004 | International Journal of Vehicle Design2004，24，23： | 1 |
| 12 | Design of Shell-and-Tube Heat Exchangers by Using CFD Technique-Part one:Thermo-Hydraulic Calculation显示文摘 | Zarko Stevanovic Gradimir Ilic | 2001 | Mechanical Engineering2001，1，8： | 1 |
| 13 | Prediction of the surface roughness of wood for machining显示文摘The surface quality of solid wood is very important for its effective response in manufacturing processes. The effects of feed rate, cutting depth and rake angle on surface roughness and power consumption were investigated and modeled. Neuro-fuzzy methodology was applied and shown that it could be useful, reliable and an effective tool for modeling the surface roughness of wood.Thus, the results of the present research can be successfully applied in the wood industry to reduce time, energy and high experimental costs. | Damjan Stanojevic Marija Mandic Gradimir Danon Srdjan Svrzic | 2017 | Journal of Forestry Research2017，28，6： | 0 |
| 14 | Editorial commentary on the special issue of Advances in Nanomedicine显示文摘Nanomedicine is a vast multidisciplinary field of life sciences.It assembles branches of the fundamental research disciplines biology,physics,and chemistry with medicine and their associated application technologies and instrumentation.Diagnostics and therapeutics are the two major application areas of nanomedicine. | Erik Reimhult Gradimir Misevic | 2021 | The Journal of Biomedical Research2021，35，4： | 0 |
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