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| 1 | Role of negative affects in pathophysiology and clinical expression of irritable bowel syndrome显示文摘Irritable bowel syndrome(IBS)is regarded as a multifactorial disease in which alterations in the brain-gut axis signaling play a major role.The biopsychosocial model applied to the understanding of IBS pathophysiology assumes that psychosocial factors,interacting with peripheral/central neuroendocrine and immune changes,may induce symptoms of IBS,modulate symptom severity,influence illness experience and quality of life,and affect outcome.The present review focuses on the role of negative affects,including depression,anxiety,and anger,on pathogenesis and clinical expression of IBS.The potential role of the autonomic nervous system,stress-hormone system,and immune system in the pathophysiology of both negative affects and IBS are taken into account.Psychiatric comorbidity and subclinical variations in levels of depression,anxiety,and anger are further discussed in relation to the main pathophysiological and symptomatic correlates of IBS,such as sensorimotor functions,gut microbiota,inflammation/immunity,and symptom reporting. | Maria Rosaria A Muscatello Antonio Bruno Giuseppe Scimeca Gianluca Polfo Rocco A Zoccali | 2014 | World Journal of Gastroenterology2014，20，24： | 9 |
| 2 | Alexithymia, Negative Emotions, and Sexual Behavior in Heterosexual University Students from Italy显示文摘 | Giuseppe Scimeca Antonio Bruno Gianluca Pandolfo Umberto Micò Vincenzo M. Romeo Elisabetta Abenavoli Adriano Schimmenti Rocco Zoccali Maria R. A. Muscatello | 2012 | Archives of Sexual Behavior2012，，1： | 1 |
| 3 | The Relationship between Alexithymia, Anxiety, Depression, and Internet Addiction Severity in a Sample of Italian High School Students显示文摘 | Giuseppe Scimeca Antonio Bruno Lucia Cava Gianluca Pandolfo Maria Rosaria Anna Muscatello Rocco Zoccali Manuel F. Casanova | 2014 | The Scientific World Journal2014，，： | 1 |
| 4 | Self-worth and psychological adjustment of obese children:An analysis through the Draw-A-Person显示文摘AIM To investigate psychopathological correlates of child obesity via the Draw-A-Person test(DAP).METHODS The participants were 50 children with a mean age of 9.74 years.Body mass index(BMI) was used as a measure of body fat.Children were divided into normal(n = 17),overweight(n = 14) and obese(n = 19).Two qualitative methods of scoring the DAP based on an integrative approach were used to assess self-concept(ESW) and overall level of children's adjustment(EAC).A procedure for judging interpretative skills of clinicians was implemented before they evaluated children's drawings.RESULTS As predicted by our hypothesis,BMI was negatively correlated with ESW,r(50) =-0.29,P < 0.05,but not with EAC,r(50) =-0.08,P = ns.To evaluate the effect of gender,Pearson correlations were re-computedregrouping the sample accordingly:BMI and EAC reached a significant negative correlation in female subjects,r(24) =-0.36,P < 0.05,and a positive correlation in male subjects,r(26) = 0.37,P = < 0.05;negative correlation between BMI and ESW became stronger in females,r(24) =-0.51,P < 0.01 but not in males,whose correlation disappeared resulting not-significant,r(26) =-0.06,P = ns.No effect of age was found.Results indicate that obesity has a negative correlation exclusively on overall adjustment and self-concept in female children.CONCLUSION It was concluded that there is a negative bias toward females that reveals how the stigma of obesity is widespread in Western society. | Giuseppe Scimeca Amelia Alborghetti Antonio Bruno Giulia Maria Troili Gianluca Pandolfo Maria Rosaria Anna Muscatello Rocco Antonio Zoccali | 2016 | World Journal of Psychiatry2016，6，3： | 0 |
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