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| 1 | CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis显示文摘 | Matilde Todaro Miriam Gaggianesi Veronica Catalano Antonina Benfante Flora Iovino Mauro Biffoni Tiziana Apuzzo Isabella Sperduti Silvia Volpe Gianfranco Cocorullo Gaspare Gulotta Francesco Dieli Ruggero De Maria Giorgio Stassi | 2014 | Cell Stem Cell2014，，3： | 3 |
| 2 | Mechanisms underlying lineage commitment and plasticity of human yo T cells显示文摘Phenotypic 和功能的异质是受动器和记忆 T 房间的特点。在抗原刺激之上, γ δT 房间区分进记忆 T 房间的二种主要类型:中央记忆房间,它巡逻血和第二等的淋巴的机关,和受动器记忆房间,它移居到外部纸巾。γ δT 房间在他们在常规 CD4 T 房间被观察的使人想起那的函数在 vitro 显示粘性的某个度。类似于 CD4 T 房间,在哪个专业化子集的过多影响主人反应, γ δT 房间可以乐意地并且很快假定不同 Th1- , Th2- , Th17- , T FH 和 T 象规章一样受动器功能,建议他们深刻地影响调停房间、体液的有免疫力的回答。除了在 cytokine 全部剧目的差别, γ δT 房间在 homing 展出差异,例如到淋巴节点滤泡的移植,到到煽动的纸巾的帮助 B 房间对移植。这里,我们考察我们 γ 的当前的理解; δT 房间系异质和灵活性与人的系统上的一个重音,并且建议受动器 γ 的一个分类; δT 房间基于不同功能的显型。 | Nadia Caccamo Matilde Todaro Guido Sireci Serena Meraviglia Giorgio Stassi Francesco Dieli | 2013 | Cellular & Molecular Immunology2013，10，1： | 2 |
| 3 | Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes Bax and Bcl-2 during left ventricular adaptations to chronic pressure overload in the rat显示文摘 | Condorelli Gianluigi Morisco Carmine Stassi Giorgio | 1999 | Circulation1999，99，： | 1 |
| 4 | Colorectal Cancer Stem Cells: From the Crypt to the Clinic显示文摘 | Ann Zeuner Matilde Todaro Giorgio Stassi Ruggero De Maria | 2014 | Cell Stem Cell2014，，6： | 1 |
| 5 | Erythropoietin Activates Cell Survival Pathways in Breast Cancer Stem–like Cells to Protect Them from Chemotherapy显示文摘 | Matilde Todaro Alice Turdo Monica Bartucci Flora Iovino Rosanna Dattilo Marco Biffoni Giorgio Stassi Giulia Federici Ruggero De Maria Ann Zeuner | 2013 | Cancer Research2013，，21： | 1 |
| 6 | Colon Cancer Stem Cells Dictate Tumor Growth and Resist Cell Death by Production of Interleukin-4显示文摘 | Matilde Todaro Mileidys Perez Alea Anna B. Di Stefano Patrizia Cammareri Louis Vermeulen Flora Iovino Claudio Tripodo Antonio Russo Gaspare Gulotta Jan Paul Medema Giorgio Stassi | 2007 | Cell Stem Cell2007，，4： | 1 |
| 7 | ROS and Lipid Droplet accumulation induced by high glucose exposure in healthy colon and Colorectal Cancer Stem Cells显示文摘Lipid Droplets(LDs)are emerging as crucial players in colon cancer development and maintenance.Their expression has been associated with high tumorigenicity in Cancer Stem Cells(CSCs),so that they have been proposed as a new functional marker in Colorectal Cancer Stem Cells(CR-CSCs).They are also indirectly involved in the modulation of the tumor microenvironment through the production of pro-inflammatory molecules.There is growing evidence that a possible connection between metabolic alterations and malignant transformation exists,although the effects of nutrients,primarily glucose,on the CSC behavior are still mostly unexplored.Glucose is an essential fuel for cancer cells,and the connections with LDs in the healthy and CSC populations merit to be more deeply investigated.Here,we showed that a high glucose concentration activated the PI3K/AKT pathway and increased the expression of CD133 and CD44v6 CSC markers.Additionally,glucose was responsible for the increased amount of Reactive Oxygen Species(ROS)and LDs in both healthy and CR-CSC samples.We also investigated the gene modulations following the HG treatment and found out that the healthy cell gene profile was the most affected.Lastly,Atorvastatin,a lipidlowering drug,induced the highest mortality on CR-CSCs without affecting the healthy counterpart. | Luca Tirinato Francesca Pagliari Simone Di Franco Elisa Sogne Maria Grazia Marafioti Jeanette Jansen Andrea Falqui Matilde Todaro Patrizio Candeloro Carlo Liberale Joao Seco Giorgio Stassi Enzo Di Fabrizio | 2020 | Genes & Diseases2020，7，4： | 0 |
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