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| 1 | 卒中治疗专业学术圆桌会议临床前推荐更新版显示文摘首份卒中治疗专业学术圆桌会议(Stroke Yherapy Academic Industry Roundtable,STAIR)推荐于1999年出版,旨在提高潜在的急性卒中治疗方法的临床前研究质量。虽然这些推荐意见被认为是合理的,但并未得到严格的遵循和验证。为了更好地向临床转化,有关候选急性卒中疗法的临床前试验的质量和广度已取得实质性进展。更新后的STAIR临床前推荐进一步强调了最初提出的建议,即通过适当的生理学监测在多种动物物种中采用组织学和功能结局来确定可重复的剂量反应和时间窗。更新后的STAIR推荐意见包括:高质量科学研究的基本原则应消除随机和评价偏倚,预先确定纳入和排除标准,计算合适的效能和样本量,并公开潜在的利益冲突。应在年轻的健康雄性动物中进行初步评价之后,在雌性、高龄动物和伴有合并症(如高血压、糖尿病和高胆固醇血症)的动物中做进一步研究。此外还要在动物实验中应用临床相关生物学标志物。尽管只有通过临床试验产生基于此的有效疗法之后才能证实该推荐意见的有效性,但遵循这些推荐有望提高成功的机会。 | Marc Fisher Giora Feuerstein David W. Howells Patricia D. Hum Thomas A. Kent Sean I. Savitz Eng H. Lo 吕志宿(译) 罗本燕(译) | 2009 | 国际脑血管病杂志2009，17，8： | 5 |
| 2 | Cultivable Microfungal Communities Inhabiting Biological Soil Crusts in the Tengger Desert, China显示文摘Biological soil crusts are essential components of arid ecosystems. We examined the variations in microfungal communities inhabiting different biological crust types in the vicinity of the Shapotou Research Station in the Tengger Desert, China. A total of134 species from 66 genera were isolated using the soil dilution plate method. The mycobiota of the crusts from the Tengger Desert,similar to that of the Negev Desert in Israel, was dominated by melanin-containing species with large multicellular spores. Abundance of these xeric species increased spatially with increasing xeric conditions from moss-dominated to cyanobacterial crusts. Density of microfungal isolates displayed the opposite trend and was positively correlated with chlorophyll content, indicating the possible significant influence of organic matter content and wetness duration on fungal biomass. Within a chronosequence of the localities of different periods after sand stabilization with revegetation, little variations were revealed in species composition and isolate density of the crust microfungal communities, while a tendency towards a decrease in the community diversity level with the crust age was noted Microfungal communities from stabilized localities differed from those of the natural localities in abundance of the dominant and some frequent species, and in the fluctuations of diversity characteristics between the cyanobacterial and moss-dominated crusts.The variations in mycobiotic parameters in the soil crusts of the Tengger Desert were apparently associated with the topographically induced variations in abiotic conditions, while the differences in microfungal community of soil crusts between the Tengger and Negev deserts, such as the significantly higher abundance of thermotolerant species in the crusts of the Tengger Deserts, were caused by the principal differences in their precipitation regimes, associated with different rainy seasons, winter and summer in the Negev and Tengger deserts, respectively. | Isabella GRISHKAN JIA Rong-Liang Giora J.KIDRON LI Xin-Rong | 2015 | Pedosphere2015，25，3： | 4 |
| 3 | Two-Year Outcomes After Sirolimus-Eluting Stent Implantation显示文摘 | Giora Weisz Martin B. Leon David R. Holmes Dean J. Kereiakes Mel R. Clark Barry M. Cohen Stephen G. Ellis Patrick Coleman Carolyn Hill Chunxue Shi Donald E. Cutlip Richard E. Kuntz Jeffrey W. Moses | 2006 | Journal of the American College of Cardiology2006，，7： | 2 |
| 4 | Possible Involvement of Stress-Activated Protein Kinase Signaling Pathway and Fas Receptor Expression in Prevention of Ischemia/Reperfusion-Induced Cardiomyocyte Apoptosis by Carvedilol显示文摘 | Tian-Li Yue Xin-Liang Ma Xinkang Wang Anne M. Romanic Gao-lin Liu Calvert Louden Juan-Li Gu Sanjay Kumar George Poste Robert R. Ruffolo Giora Z. Feuerstein | 1998 | Circulation Research1998，，2： | 2 |
| 5 | Understanding figurative and literal language: The graded salience hypothesis显示文摘 | Giora R | 1997 | Cognitive Linguistics1997，，7： | 1 |
| 6 | On the priority of salient meanings: Studies of literal and figurative language显示文摘 | Giora R | 1999 | Journal of Pragmatics1999，，31： | 1 |
| 7 | Adsorption-desorption of chlordimeform on montmorillonite: Effect of clay aggregation and competitive adsorption with cadmium 显示文摘 | Tomas Undabeytia Shlomo Nir Tamara Polubesova Giora Rytwo Esmeralda Morillo Celia Maqueda | 1999 | Environ Sci Technol1999，33，： | 1 |
| 8 | Salience and context effects: Two are better than one显示文摘 | Giora R | 2001 | Metaphor and Symbol2001，，16： | 1 |
| 9 | On the informativeness requirement显示文摘 | Giora V | | 0，，： | 1 |
| 10 | Understanding Figurative and Literal Language : The Graded Salience Hypothesis 显示文摘 | Giora Rachel | 1997 | Cognitive Linguistics1997，8，3： | 1 |
| 11 | Morphology-dependent resonances of a microsphere-optical fiber system 显示文摘 | GIORA G STEPHEN A | 1996 | Optics Letters1996，21，10： | 1 |
| 12 | When is Relevance? On the Role of Salience in Utterance Interpretation 显示文摘 | Giora Rachel | 1998 | Revista Alicantina de Estudios Ingleses1998，11，： | 1 |
| 13 | Upper airway length may be associated with the severity of obstructive sleep apnea syndrome显示文摘 | Yosef Segal & Atul Malhotra & Giora Pillar | 2008 | Sleep Breath2008，12，： | 1 |
| 14 | On the Priority of Salient Meanings: Studies of Literal and Figurative Language 显示文摘 | GIORA R | 1999 | Journal of Pragmaties1999，，31： | 1 |
| 15 | Partial purification and some properties of polyphanol oxidase extracted from litchi fruit pericarp 显示文摘 | Jiang Y M Giora Z Yoram F | 1997 | Po~tharvest Biology and Technology1997，10，3： | 1 |
| 16 | Minimal aspect distortion (mad) mosaicing of long scenes显示文摘 | ALEX Rav Acha GIORA Engel SHMUEL Peleg | 2008 | InternationalJournal of Computer Vision2008，78，23： | 1 |
| 17 | Discourse coherence and theory of relevance:Stumbling blocks in search of a unified theory显示文摘 | R | 1997 | Journal of Pragmatics1997，，27： | 1 |
| 18 | Seismic communication in a blind subterranean: A major somatosensory mechanism in adaptive evolution underground 显示文摘 | EVIATAR N GIORA H HILLEL P | 1991 | Proc Natl Acad Sci1991，88，： | 1 |
| 19 | Anticholinergic and antiglutamatergic agents protect against Soman-induced brain damage and cognitive dysfunction显示文摘 | Lily R Ben A W Giora C | 2003 | Toxicol Sci2003，75，： | 1 |
| 20 | Discourse coherence is an independent notion:A reply to Deidre Wilson显示文摘 | R | 1998 | Journal of Pragmatics1998，29，： | 1 |
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