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| 1 | Differing profiles of people diagnosed with acute and chronic hepatitis B virus infection in British Columbia,Canada显示文摘AIM To describe the characteristics of people diagnosed with acute and chronic hepatitis B virus(HBV) infection in British Columbia(BC).METHODS We used data from the BC Hepatitis Testers Cohort(BCHTC),which includes all individuals tested for hepatitis C virus(HCV) or human immunodeficiency virus(HIV) or those diagnosed with HBV or active tuberculosis in BC since 1990.These data were integrated with prescription drug,medical visit,hospitalization and mortality data.HBV cases were classified as acute or chronic according to provincial guidelines.We compared characteristics of individuals by HBV infection group(acute,chronic and negative).Factors associated with acute or chronic HBV infection were assessed with multinomial logistic regression models in comparison to the HBV negative group.RESULTS46498 of the 1058056 eligible BC-HTC participants were diagnosed with HBV infection.4.3% of HBV positive individuals were diagnosed with acute HBV infections while 95.7% had chronic infections.Problematic alcohol use,injection drug use,and HIV or HCV co-infection were more common among individuals diagnosed with acute HBV compared to those with chronic infections and HBV negative individuals.In multivariable multinomial logistic regression models,we observed significant associations between acute or chronic HBV diagnosis and being male,age at HBV diagnosis or birth cohort,South and East Asian ethnicity,HCV or HIV infection,and injection drug use.The odds of acute HBV decreased with increasing age among people who inject drugs,while the opposite was true for chronic HBV.Persons with acute HBV were predominantly White(78%) while those with chronic HBV were mostly East Asian(60%).Relative to Whites,East Asians had 12 times greater odds of being diagnosed with chronic HBV infection.These odds increased with increasing socioeconomic deprivation.CONCLUSION Differences in the profiles of people diagnosed with acute and chronic HBV infection necessitate differentiated screening,prevention,care and treatment programs. | Mawuena Binka Zahid A Butt Stanley Wong Mei Chong Jane A Buxton Nuria Chapinal Amanda Yu Maria Alvarez Maryam Darvishian Jason Wong Gina McGowan Mikhail Torban Mark Gilbert Mark Tyndall Mel Krajden Naveed Z Janjua | 2018 | World Journal of Gastroenterology2018，24，11： | 3 |
| 2 | Performance of full cells containing carbonate-based Li FSI electrolytes and silicon-graphite negative electrodes显示文摘 | TRASK S E PUPEK K Z GILBERT J A | 2016 | Journal of the Electrochemical Society2016，163，3： | 1 |
| 3 | Are tropical fungalendophytes hyperdiverse显示文摘 | Arnold A E Maynard Z Gilbert G S | 2000 | Ecological Letters2000，3，4： | 1 |
| 4 | Guillain - Barr6 syndrome - related Campylobacter jejuni in Bangla- desh: ganglioside mimicry and cross -reactive antibodies 显示文摘 | Islam Z Gilbert M Mohammad QD | 2012 | PlosOne2012，7，43： | 1 |
| 5 | Geochemical application of steranes and triterpane biomarkers to a description of oils from the Taranaki basin in New Zealand显示文摘 | Czochanska Z Gilbert T D Philp R P | 1988 | Organic Geochemistry1988，12，： | 1 |
| 6 | Diclofenac residues as the cause of vulture population decline in Pakistan显示文摘 | Oaks J L Gilbert M Virani M Z | 2004 | Nature2004，427，： | 1 |
| 7 | Structure and properties of talc-filled polypropylene:Effect of phosphate coating显示文摘 | Liu Z Gilbert M | 1996 | J Appl Poly Sei1996，59，7： | 1 |
| 8 | Special phase transformation and crystal growth pathways observed in nanoparticles 显示文摘 | GILBERT B ZHANG H Z HUANG F FINNEGAN M P WAYCHUNAS G A BANFIELD J F | 2003 | Geochemical Transactions2003，4，4： | 1 |
| 9 | Tissue-plas- minogen activator is induced as an immediate-early gene dur- ing seizure, kindling and long- term potentiation 显示文摘 | QIAN Z GILBERT M E COLICOS M A | 1993 | Nature1993，361，6411： | 1 |
| 10 | Genetic characterization of QTL associated with resistance to Fusarium head blight in a doubled haploid spring wheat population显示文摘 | Yang Z P Gilbert J Fedak G | 2005 | Genome2005，48，： | 1 |
| 11 | Are tropical fungal endophytes hyperdiverse显示文摘 | ARNOLD A E MAYNARD Z GILBERT G S | 2000 | Ecological Letters2000，3，4： | 1 |
| 12 | Wavelet neural networks for function learning 显示文摘 | Gilbert G W Yubo M | 1995 | IEEE Transactions on Signal Processing1995，43，6： | 1 |
| 13 | Fungal endophytes in dicotyledonous neotropical trees:patterns of abundance and diversity显示文摘 | Arnold A E Maynard Z Gilbert G S | 2001 | Mycol Res2001，105，： | 1 |
| 14 | Wavelet neural networks for function learning 显示文摘 | JUN Z GILBERT G W YUBO M | 1995 | IEEE Transactions on Signal Processing1995，43，6： | 1 |
| 15 | Surgical anatomy of spinal accessory nerve:is trapezius functional deficit inevitable after division of the nerve?显示文摘 | DAILIANA Z H MEHDIAN H GILBERT A | 2001 | J Hand Surg[Br]2001，26，2： | 1 |
| 16 | Endothelin receptor antagonism ameliorates mast cel infiltration,vascular hypertrophy,and epidermal growth factor expression in experimental diabetes显示文摘 | Gilbert RE Rumble JR Cao Z | | 0，，02： | 1 |
| 17 | Geochemical Application of Sterane and Triterpane Biomarkers to a Description of Oils from the Taranaki Basin in New Zealand显示文摘 | Gilbert T D Philp R P | 1988 | Organic Geochemistry1988，12，2： | 1 |
| 18 | Immunoaffinity column clean-up tech- niques in food analysis: A review 显示文摘 | Senyuva H Z Gilbert J | 2010 | Journal of Chromatogra phy B2010，，878： | 1 |
| 19 | Supplier encroachment under asymmetric information显示文摘 | LI Z X GILBERT S M LAI G M | 2014 | Management Science2014，60，2： | 1 |
| 20 | Determination of aflatoxins and ochratoxin A in high-sugar-content traditional Turkish foods by affinity column cleanup and LC fluorescence detection显示文摘 | SENYUVA H Z CIMEN D GILBERT J | 2009 | J AOAC Int2009，92，4： | 1 |
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