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| 1 | 加压螺钉治疗舟骨骨折的临床疗效显示文摘目的 评价加压螺钉内固定治疗舟骨骨折的临床疗效。方法 对 46例 (4 7侧 )舟骨骨折采用切开复位加压螺钉内固定治疗的患者 ,术后进行随访。从术后疼痛程度、腕关节活动度、手部握力、影像学检查、Krimmer腕关节评分和DASH(DisabilityofArm Shoulder Hand)问卷调查表等进行随访和疗效评估。结果 术后腕关节疼痛程度静息时为 2 ,用力时为 13。腕关节屈伸活动度 12 4°(达健侧 92 % ) ,尺桡偏5 7°(达健侧 91% ) ,平均握力 47kg(达健侧 90 % )。X线片及CT检查 :6例螺钉穿透骨皮质 ,4例发生腕关节炎 ,1例舟骨骨折不愈合及 1例畸形愈合。Krimmer评分总体疗效 :优 3 9侧 ,良 5侧 ,满意 3侧。DASH值为8 3。DASH问卷调查表结果显示 ,术后腕关节功能良好 ,仅有轻微不适症状。结论 应用切开复位加压螺钉内固定治疗舟骨骨折手术操作简便、疗效可靠。 | 陈振兵 洪光祥 王发斌 Germann G | 2005 | 中华手外科杂志2005，21，1： | 31 |
| 2 | Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: Clinico-pathogenic aspects显示文摘Toll-like receptors (TLRs) recognize specific motifs which are frequently present in bacteria, fungi, prokaryotes and viruses. Amongst TLRs, TLR9 can be activated by such bacterial or viral DNA fragments, immunoglobulin-DNA complexes or synthetic oligonucleotides, which all contain unmethylated cytosineguanine nucleotide sequences (CpGs). Emerging data indicate that TLR9 signaling has a role in, and may influence, colorectal carcinogenesis and colonic inflammation. CpGs are classified into three groups according to their influence on both the antigen-specific humoraland cellular immunity, and the production of type 1 interferons and proinflammatory cytokines. TLR9 activation via CpGs may serve as a new therapeutic target for several cancerous and various inflammatory conditions. Due to its probable anti-cancer effects, the application possibilities of TLR9-signaling modulation may be extremely diverse even in colorectal tumors. In this review we aimed to summarize the current knowledge about TLR-signaling in the pathogenesis and therapy of inflammatory bowel diseases and colorectal cancer. Due to the species-specific differences in TLR9 expression, however, one must be careful in translating the animal model data into the human system, because of the differences between CpG-oligodeoxynucleotide-responsive cells. TLR9 agonist DNA-based immunomodulatory sequences could also represent a promising therapeutic alternative in systemic inflammatory conditions and chronic colonic inflammations as their side effects are not significant. | István Fri Ferenc Sipos Tiana M Germann Alexandra Kalmár Zsolt Tulassay Béla Molnár Gyrgyi Mzes | 2013 | World Journal of Gastroenterology2013，19，26： | 14 |
| 3 | 高分辨率CT在舟骨骨折诊断和治疗中的应用价值显示文摘目的 评价高分辨率CT在急性舟骨骨折诊断和治疗中的应用价值。方法 术前对 46例47侧舟骨骨折患者进行腕关节常规X线片检查 ,其中对 2 7例采用高分辨率CT检查。术后对全部 47侧腕关节进行X线片及CT检查。结果 术前 42侧腕关节X线检查显示舟骨骨折 ,5侧未能显示。CT检查明确显示 2 7例舟骨骨折的部位、骨折移位和粉碎的情况。术后发生舟骨骨折不愈合、畸形愈合、螺钉的位置以及创伤性关节炎等均可在CT扫描时清楚显示。结论 CT检测能提高舟骨骨折的诊断水平 ,为临床制定治疗方案提供可靠依据。 | 陈振兵 洪光祥 Germann G | 2004 | 中华手外科杂志2004，20，3： | 9 |
| 4 | Martin螺钉经皮穿针内固定治疗非移位性舟骨骨折显示文摘 | 陈振兵 洪光祥 Germann G | 2006 | 中华骨科杂志2006，26，2： | 7 |
| 5 | Antioxidative properties of the gastrointestinal phytopharmaceutical remedy STW 5 (Iberogast ? )显示文摘 | I. Germann D. Hagelauer O. Kelber B. Vinson S. Laufer D. Weiser H. Heinle | 2006 | Phytomedicine2006，，： | 2 |
| 6 | Cerebral gnathostomiasis as a cause of an extended intracranial bleeding显示文摘 | Germann R Sch chtele M Nessler G | 2003 | Kiln Padiatr2003，215，4： | 1 |
| 7 | Microscopic view of structural phase transitions induced by shock waves显示文摘 | Kadau K Germann T C Lomdahl P S | 2002 | Science2002，296，： | 1 |
| 8 | Macropores and water flow in soils显示文摘 | Beven K Germann P | 1982 | Water Resources Research1982，18，5： | 1 |
| 9 | Are urban green spaces opti- mally distributed to act as social integration? Results of a geographical information system (GIS) approach for urban forestry research 显示文摘 | GERMANN C SEELAND K | 2004 | Forest Policy and Economics2004，6，： | 1 |
| 10 | Locally applied vascular endothelial growth factor A increases the osteogenic healing capacity of human adipose-derivedstem cells by promoting osteogenic and endothelial differentiation显示文摘 | Behr B Tang C Germann G | 2011 | Stem Cells2011，29，2： | 1 |
| 11 | Complications after emergency tube thoracostomy:assessment with CT显示文摘 | Baldt MM Bankier AA Germann PS | | 0，，02： | 1 |
| 12 | The value of early enteral nutrition in the prophylaxis of stress ulceration in the severely burned patient显示文摘 | Raff T Germann G Hartmann B | 1997 | Burns1997，23，4： | 1 |
| 13 | Neurobehavioral evaluation of rhesus monkey infants fed cow's milk formula,soy formula,or soy formula with added manganese显示文摘 | Golub MS Hogrefe CE Germann SL | | 0，，04： | 1 |
| 14 | Paroxetine hydrochloride显示文摘 | P Germann D Ma G Han F | 2013 | rofiles Drug Subst Excip Relat Methodol2013，38，： | 1 |
| 15 | Water flow in soil macropores Ⅱ :A combined flow model显示文摘 | Beven K Germann P | 1981 | J Soil Sci1981，32，： | 1 |
| 16 | Regulation of laccase synthesis in induced Neurospora crassa cultures显示文摘 | Linden R M Schilling B C Germann U A | 1991 | Current Genetics1991，19，5： | 1 |
| 17 | Interleukin-12 profoundly up -regulates the synthesis of antigen -specific complement-fixing IgG2a, IgG2b and IgG3 antibody subclasses in vivo显示文摘 | Germann T Bongartz M Dlugonska H | 1995 | Eur J Immunol1995，25，： | 1 |
| 18 | Microscopic view of structural phase transitions induced by shock waves显示文摘 | Kadau K Germann T C Lomdahl P S | 2002 | Science2002，296，5573： | 1 |
| 19 | Administration of interleukin 12 in combination with type Ⅱ collagen induces severe arthritis in DBA/1mice显示文摘 | Szeliga J Storkel S | 1995 | Proc Natl Acad Sci USA1995，92，11： | 1 |
| 20 | Specification of fine steering mir- rors for line-of-sight stabilization sytems显示文摘 | GERMANN L M | 1991 | SHE1991，1543，： | 1 |
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